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GEORGE TOWN, KY, Oct 28, 2025 - (ACN Newswire via SeaPRwire.com) - Octo Horizon, a proprietary trading firm specializing in high-frequency trading (HFT), is advancing the next generation of trading infrastructure - where engineering excellence, low-latency systems, and high-performance software drive measurable results.octo-horizon-high-performance-infrastructureEngineering-driven infrastructure at Octo Horizon powers next-generation trading technology.The firm approaches trading as a large-scale engineering challenge, focusing on optimizing system performance, network throughput, and execution speed. Engineers at Octo Horizon work on cutting-edge infrastructure using C++, concurrency design, and deterministic architectures to ensure reliable, predictable operation under demanding conditions. Kernel-bypass networking, lock-free data structures, and real-time analytics are among the tools applied to reduce latency and maximize efficiency.Engineering at the CoreEngineering precision is central to Octo Horizon's philosophy. Teams collaborate on high-performance software, distributed systems, and real-time data processing, tuning every layer - from network drivers to execution logic - to achieve optimal performance. Continuous benchmarking, profiling, and performance analysis are embedded in the development workflow to maintain stable, predictable results.Developers also engage in rigorous testing frameworks, including unit, integration, and stress testing, to validate system reliability under peak load conditions. Tooling for monitoring, logging, and performance visualization is integrated into the workflow, allowing engineers to identify bottlenecks and optimize system throughput at the nanosecond scale.Technology PhilosophyFor Octo Horizon, trading is a technical pursuit. The firm emphasizes simplicity, reproducibility, and system-level optimization, solving complex problems in low-latency networking, asynchronous processing, and event-driven architectures. Teams design modular, maintainable systems that scale efficiently and adapt to evolving market conditions, while minimizing resource overhead.Real-time decision-making and deterministic behavior are central, with every system component evaluated for latency, concurrency, and stability. This approach ensures that the firm's technology remains reliable, resilient, and capable of supporting high-throughput electronic markets.Culture and CollaborationOcto Horizon fosters a collaborative and innovation-driven environment. Engineers, systems developers, and quantitative researchers work closely across disciplines to exchange ideas, review designs, and refine implementations. Autonomy, technical curiosity, and attention to detail are highly valued, creating a culture where individual expertise drives measurable impact and continuous improvement.Opportunities for Engineers and ResearchersOcto Horizon is expanding its technology and research teams and is actively hiring for the following positions:Quantitative ResearcherSoftware EngineerDevOps EngineerCandidates passionate about high-performance computing, distributed systems, and low-latency software are encouraged to apply. The firm offers an environment that rewards technical mastery, curiosity, and innovation - with the opportunity to work on challenging real-world problems with visible results.For more information and to apply, visit https://www.octo-horizon.com/jobsContact InformationMedia Octo Horizonservice@octo-horizon.comSOURCE: Octo Horizon Copyright 2025 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

Brisbane, Australia--(ACN Newswire via SeaPRwire.com - October 28, 2025) - Graphene Manufacturing Group Ltd. (TSXV: GMG) (OTCQX: GMGMF) ("GMG" or the "Company") is pleased to announce that Beijer Ref has agreed to offer the Company's proprietary THERMAL-XR® ENHANCE heat transfer coating as an optional coating solution on Beijer Ref and Kirby branded refrigeration evaporator coils, including the Beijer Patton and Kirby Guardian lines as seen in Figure 1, across all of Beijer Ref's and Kirby's approximately 73 wholesale locations in Australia starting from 17 November 2025. Beijer Ref customers electing to have the optional coating solution applied to their Beijer Ref or Kirby refrigeration evaporator coils will contract directly with Beijer Ref, who will enter into a bilateral agreement with the Company, subject to GMG's standard terms and conditions. This collaboration marks a significant milestone in GMG's commercialization of its innovative coating products for energy efficiency and corrosion resistance in the HVAC-R industry.Figure 1: Beijer Patton Evaporator Coil and Kirby Guardian Evaporator CoilTo view an enhanced version of this graphic, please visit:https://images.newsfilecorp.com/files/8082/272201_gmg_figure1_550.jpgWhile the collaboration is for an indeterminate period, the Company anticipates that as the advantages of THERMAL-XR® ENHANCE are experienced by customers electing to have the coating applied, the benefits to both Beijer Ref and the Company will support a long-term arrangement. However, at present either party may terminate the collaboration at any time.Beijer Ref is one of the world's largest global refrigeration and HVAC wholesalers, headquartered in Malmö, Sweden, with operations spanning more than 40 countries and over 500 branches worldwide, 6,000 employees and 200,000 customers. In Australia, Beijer Ref Group distributes through Kirby, Beijer Ref Australia, SCM REF Australia, and ACD Trade, providing air conditioning and refrigeration equipment, components, and engineering solutions. The company serves diverse sectors such as supermarkets, cold storage, and industrial refrigeration, combining expertise with local manufacturing and distribution capabilities.GMG's THERMAL-XR® ENHANCE coating utilizes the Company's unique graphene-based formulation to improve the thermal performance and longevity of heat exchange surfaces. The application of this coating to Beijer Patton and Kirby Guardian evaporator coils is expected to enhance corrosion resistance, cooling efficiency, reduce energy consumption and provide sustainability benefits across diverse cooling environments. This initiative extends the availability of GMG's product through Beijer Ref's extensive distribution network while offering Australian customers improved system performance and energy/emission reduction pathways.GMG plans to utilize a network of trained and approved HVAC contractors to apply its THERMAL-XR® ENHANCE coating on refrigeration and air-conditioning coils for this roll out for coating Beijer Ref products starting in the capital cities of mainland Australia. Each participating contractor will undergo GMG certification in the GMG SPRAY ACADEMY to ensure they are proficient in the coating's three-stage process: surface cleaning and preparation, graphene-based coating application, and post-application inspection and maintenance verification. This ensures consistent quality, adherence to safety protocols, and correct use of GMG's proprietary application methods.These certified contractors will deliver coating services on-site or at pre-approved GMG spray coating plants nationally, enabling GMG to scale deployment seamlessly through both direct and distributor channels, particularly in collaboration with Beijer Ref and Kirby stores. By drawing on established HVAC service professionals, the Company ensures local availability, rapid turnaround for installations, and full compliance with the quality standards required for quality assurance.This contractor program forms part of GMG's strategic commercialization model, where trained technicians act as frontline partners in the installation of graphene-enhanced coatings for end users. The approach maximizes accessibility, maintains warranty integrity, and strengthens GMG's reputation for technical excellence and customer support across Australia's HVAC-R market.GMG's Chief Executive Officer, Craig Nicol, commented: "We are proud to see THERMAL-XR® ENHANCE incorporated into Beijer Ref's and Kirby's product offerings in Australia as an option for their leading HVAC-R products. This partnership demonstrates the growing recognition of graphene-enhanced materials as a viable route to corrosion resistance and greater efficiency in conventional HVAC-R systems. The Company continues to expand its market reach globally through strategic channel partners and remains committed to advancing environmentally responsible technologies through graphene innovation."GMG's Chairman and Non-Executive Director, Jack Perkowski, commented "Congrats to the team – great to see this next step in the roll out of GMG's global leading energy saving products."About GMG:GMG is an Australian based clean-technology company which develops, makes and sells energy saving and energy storage solutions, enabled by graphene manufactured via in house production process. GMG uses its own proprietary production process to decompose natural gas (i.e. methane) into its natural elements, carbon (as graphene), hydrogen and some residual hydrocarbon gases. This process produces high quality, low cost, scalable, 'tuneable' and low/no contaminant graphene suitable for use in clean-technology and other applications.The Company's present focus is to de-risk and develop commercial scale-up capabilities, and secure market applications. In the energy savings segment, GMG has initially focused on graphene enhanced heating, ventilation and air conditioning ("HVAC-R") coating (or energy-saving coating) which is now being marketed into other applications including electronic heat sinks, industrial process plants and data centres. Another product GMG has developed is the graphene lubricant additive focused on saving liquid fuels initially for diesel engines.In the energy storage segment, GMG and the University of Queensland are working collaboratively with financial support from the Australian Government to progress R&D and commercialization of graphene aluminium-ion batteries ("G+AI Batteries"). GMG has also developed a graphene additive slurry that is aimed to improve the performance of lithium-ion batteries.GMG's 4 critical business objectives are:Produce Graphene and improve/scale cell production processesBuild Revenue from Energy Savings ProductsDevelop Next-Generation BatteryDevelop Supply Chain, Partners & Project Execution CapabilityFor further information please contact:Craig Nicol, Chief Executive Officer & Managing Director of the Company at craig.nicol@graphenemg.com, +61 415 445 223Leo Karabelas at Focus Communications Investor Relations, leo@fcir.ca, +1 647 689 6041Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accept responsibility for the adequacy or accuracy of this news release.Cautionary Note Regarding Forward-Looking Statements This news release includes certain statements and information that may constitute forward-looking information within the meaning of applicable Canadian securities laws. Forward-looking statements relate to future events or future performance and reflect the expectations or beliefs of management of the Company regarding future events. Generally, forward-looking statements and information can be identified by the use of forward-looking terminology such as "intends", "expects" or "anticipates", or variations of such words and phrases or statements that certain actions, events or results "may", "could", "should", "would" or will "potentially" or "likely" occur. This information and these statements, referred to herein as "forward‐looking statements", are not historical facts, are made as of the date of this news release and include without limitation, statements regarding the offering of THERMAL-XR® ENHANCE heat transfer coating on Beijer Ref and Kirby branded refrigeration evaporator coils, THERMAL-XR® ENHANCE's ability to enhance corrosion resistance, cooling efficiency, reduce energy consumption, and provide sustainability benefits across diverse cooling environments, improve system performance and energy/emission reduction pathways, the intention to utilize a network of trained and approved HVAC contractors to apply its THERMAL-XR® ENHANCE coating, the proficiency of contractors in the application of THERMAL-XR® ENHANCE, the delivery of coating services on-site or at pre-approved GMG spray coating plants, the Company's ability to scale deployment seamlessly, the Company's ability to ensure local availability, rapid turnaround for installations, and full compliance with the quality standards required for quality assurance, the strategic commercialization model's ability to maximize accessibility, maintain warranty integrity, and strengthen GMG's reputation for technical excellence and customer support across Australia's HVAC-R market, the growth in recognition of graphene-enhanced materials as a viable route to corrosion resistance and greater efficiency in conventional HVAC-R systems, the Company's continued expansion of its market reach globally through strategic channel partners and the Company's commitment to advancing environmentally responsible technologies through graphene innovation.Such forward-looking statements are based on a number of assumptions of management, including, without limitation, that GMG will be able to take orders and deliveries to meet distributor demand around the worldwide. Additionally, forward-looking information involves a variety of known and unknown risks, uncertainties and other factors which may cause the actual plans, intentions, activities, results, performance or achievements of GMG to be materially different from any future plans, intentions, activities, results, performance or achievements expressed or implied by such forward-looking statements. Such risks include, without limitation, that products may not be available for sales or delivery to meet customers' expectations.Although management of the Company has attempted to identify important factors that could cause actual results to differ materially from those contained in forward-looking statements or forward-looking information, there may be other factors that cause results not to be as anticipated, estimated or intended. There can be no assurance that such statements will prove to be accurate, as actual results and future events could differ materially from those anticipated in such statements. Accordingly, readers should not place undue reliance on forward-looking statements and forward-looking information. Readers are cautioned that reliance on such information may not be appropriate for other purposes. The Company does not undertake to update any forward-looking statement, forward-looking information or financial out-look that are incorporated by reference herein, except in accordance with applicable securities laws. To view the source version of this press release, please visit https://www.newsfilecorp.com/release/272201 Copyright 2025 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

- The 20th edition of Eco Expo Asia opens today for four days at AsiaWorld-Expo, gathering some 340 exhibitors from 13 countries and regions- The Expo features diverse activities and product technologies in response to the Policy Address, covering three key areas – Circular Economy and Waste Management, Green & Smart Mobility and ESG-related Services- The ‘Experience Sharing Forum on Promoting Environmental Business in Overseas Markets’ will be held tomorrow. Government officials and representatives of quasi-governmental organisations from Belt and Road countries will share strategies for local market development, to help green companies expand their international networksHONG KONG, Oct 28, 2025 - (ACN Newswire via SeaPRwire.com) – The 20th Eco Expo Asia, jointly organised by the Hong Kong Trade Development Council (HKTDC) and Messe Frankfurt (HK) Ltd and co-organised by the Environment and Ecology Bureau of the Government of the Hong Kong Special Administrative Region (HKSAR), opened at AsiaWorld-Expo today and runs until 31 October. Some 340 exhibitors from 13 countries and regions are showcasing innovative green technologies and products, as well as ESG and sustainable solutions. The last day of the Expo, 31 October, will open to the public for free, to encourage sustainable living practices.Yu Huiwen, Vice Minister of the Ministry of Ecology and Environment of the People’s Republic of China; Ding Zhijun, Deputy Director of the Department of Energy Conservation and Comprehensive Utilization, Ministry of Industry and Information Technology of the People’s Republic of China; Tse Chin-wan, Secretary for Environment and Ecology of the Hong Kong SAR Government; HKTDC Executive Director Sophia Chong; and Richard Li, Executive Director of Messe Frankfurt (HK) Ltd, attended Eco Expo’s opening ceremony today.HKTDC Executive Director Sophia Chong said: “This year, we celebrate a significant milestone of the Expo - its 20th edition. This not only marks our commitment to sustainability but also underscores our ongoing mission to develop the ecosystem for driving innovation and collaboration to support the green agenda. Under the theme ‘Green Innovations for Carbon Neutrality’, Eco Expo Asia provides invaluable opportunities for the green industry. This year, once again, we are bringing together leading players from the eco sector to pave the way for a more sustainable future, in alignment with the Hong Kong SAR Government’s net zero goals.”Speaking at the opening ceremony, the Secretary for Environment and Ecology, Tse Chin-wan, said, "In the global journey towards sustainability, Hong Kong serves as a ‘super connector’. With our unique position as an international city within the Guangdong-Hong Kong Macao Greater Bay Area and a bridge between Chinese Mainland and the world, Hong Kong brings together talent, technology, and capital to foster collaboration and scale up green innovation.Global exhibitors gather to showcase innovative environmental technologiesThis year’s Expo brings together 17 pavilions. For the first time, the Environmental Campaign Committee is hosting a pavilion, presenting 22 local green start-ups, alongside a joint government pavilion featuring 11 bureaux and departments, including the Environment and Ecology Bureau. Chinese Mainland delegations from Guangdong, including Guangzhou and Shenzhen, Guangxi, Hunan, Inner Mongolia and Shanghai are also joining the Expo. The ANSO Environmental Technology Industry Alliance, led by the Alliance of National and International Science Organizations for the Belt and Road Regions (ANSO), is making its debut, together with 11 mainland enterprises, showcasing technologies related to water resources and the atmospheric environment, and laying the foundation for future expansion overseas. New overseas pavilions include Italy and South Korea, while Canada, the Netherlands and Norway are returning this year.The Expo is also actively building a platform to support Hong Kong and mainland enterprises to go global and explore new opportunities in green trade, attracting buyers from Japan, Thailand, Indonesia, Malaysia, Singapore, Vietnam, Hungary and Poland to visit and source at the event. For tomorrow’s ‘Experience Sharing Forum on Promoting Environmental Business in Overseas Markets’, the Hong Kong SAR Government has invited government officials and representatives from quasi-governmental organisations from Belt and Road countries to share strategies to develop local markets. In collaboration with the Environment and Ecology Bureau, the Expo extends invitations to government service providers from the Chinese Mainland, as well as from ASEAN and Belt and Road countries, to visit and source green technologies and products.Three major green and smart areas supporting the Policy AddressEnvironmental protection has become a key policy focus in recent years. The Chinese Government recently released guidelines on advancing low-carbon transition and strengthening the development of China’s carbon trading market. This year’s Policy Address highlighted new directions in green policy in Hong Kong, including fostering green and low-carbon living environments, and expediting the application of green technologies. In line with industry development, the Expo brings together a diverse range of green tech, showcasing the latest achievements in Circular Economy and Waste Management, Green & Smart Mobility and ESG-related Services.In Circular Economy and Waste Management, Green AI Technology Limited (Booth No. 3-D38) displays its AI-powered smart sorting bin with real-time waste identification, demonstrating good recycling methods through interactive learning. Dynagreen Environmental Protection Group Co., Ltd (Booth No. 3-E30) showcases its comprehensive waste treatment project, contributing to sustainable urban development.In Green & Smart Mobility, SANY Turbo Fly Machine Limited (Booth No. 6-C26) from Hong Kong and Macao, a subsidiary of SANY Group, a leading equipment manufacturing company in the Chinese Mainland, brings its SANY Mobile Charging Power Station, which can charge two electric trucks simultaneously. CIMC Enric Investment Holding (Shenzhen) Co., Ltd. (Booth No. 3-F14), a leading manufacturer of advanced clean energy equipment, showcases innovative hydrogen and green methanol technology solutions for transportation and storage.The Expo also showcases ESG-related services. Llewellyn and Partners Company Limited (Booth No. 6-D14) displays AutoTwin, a patented AI-powered integrated management platform for the construction industry, which helps reduce building operating costs, time and carbon emissions. XSIM AI Canada Inc.,(Booth No. 6-C23), a Canadian technology company, empowers wastewater and industrial facilities with its AI-driven system to reduce downtime and lower operational costs, while cutting carbon emissions by up to 30% .Research institutions and start-ups also play a significant role in the Expo. In addition to the return of The Chinese University of Hong Kong (Booth No. 3-G24), Lingnan University (Booth No. 6-A25) and the Hong Kong Polytechnic University Jinjiang Technology and Innovation Research Institute (Booth No. 6-A23) are joining for the first time this year. The Hong Kong Science and Technology Parks Corporation (Booth No. 3-F20) presents start-up afterNATURE (Booth No. 3-F20), which is showcasing its Deep Hexagonal Basin product. This innovation creates habitats for marine life on its surface, helping to preserve coastal biodiversity. Another start-up, Formwork IO (Booth No. 3-F20), exhibits AtmosBrick and is globally debuting AtmosTile at the Expo. These ‘carbon-negative’ building materials are designed to help reduce carbon emissions.Eco Asia Conference brings together industry leaders, focusing on construction and transportation sectorsEco Expo’s highlight event, Eco Asia Conference, began today with the Government Session. Ding Zhijun, Deputy Director of the Department of Energy Conservation and Comprehensive Utilization, Ministry of Industry and Information Technology of the People’s Republic of China, shared the country’s latest environmental policies and trends. Officials from Myanmar, Sri Lanka, the Philippines and other Belt and Road countries also elaborated on their latest green policies and projects. Another session, ‘Revolutionising with Circular Economy: From Waste to Innovative Solutions’, featured experts led by the Business Environment Council, who explored the application of circular economy concepts in business operations. The Hong Kong Circular Built Environment Guidebook is also making its debut at the Conference, providing the latest green guidelines for the construction industry.On the third day of the Expo, on 30 October, the Conference will have two main themes: ‘Building a Sustainable Future: Gearing Towards a Net-Zero Built Environment’ and ‘Green & Smart Mobility – Envisioning the Future of Transportation’. Industry leaders and experts, including Pak-cheung Chan, Deputy Director, Electrical and Mechanical Services Department, Hong Kong SAR Government, and Dr Rick Mo, Head of the Centre of Advanced Power and Autonomous Systems (APAS), Hong Kong Productivity Council, will share insights and discuss how the construction and transportation industries can build sustainable cities through effective collaboration.Other exciting activities include the FHKI Q-Mark Low Carbon Restaurant Award 2025 on 28 October, the first day of the Expo. The 6th Hydrogen Economy Forum will be held on the second day of the Expo, on 29 October. Diane Wong, JP, Under Secretary for Environment and Ecology, Hong Kong SAR Government will deliver the keynote address, while Dr Wang Ziyuan, Vice President, China Hydrogen Development and Innovation Alliance for Urban Gas will share insights on the opportunities and challenges of hydrogen energy in the Guangdong-Hong Kong-Macao Greater Bay Area. The Expo also features various seminars, including ‘Startup Edge’, which promotes the development of green start-ups, featuring presentations by start-up representatives from various environmental fields.On 31 October, Eco Expo will open to the public free of charge, to encourage public participation in environmental initiatives through a series of talks, workshops and activities. These include a seminar on the recent hot topic of extreme weather by Man Yee Chan, Chief Experimental Officer, Hong Kong Observatory, and a presentation by Ocean Park on Mission R, an initiative to protect endangered wildlife and their habitats. The public can also participate in various environmental workshops, and purchase eco-friendly products from the Green Mart.Other concurrent eventsThe Hong Kong International Outdoor and Tech Light Expo takes place from 28 to 31 October at AsiaWorld-Expo, showcasing outdoor and professional technical lighting solutions for commercial and industrial use; while the Hong Kong International Lighting Fair (Autumn Edition) opened yesterday and will run until 30 October at the Hong Kong Convention and Exhibition Centre. Free shuttle bus services are offered between these venues and other locations in the city throughout the fair period. Please refer to the following page for details:https://www.hktdc.com/event/ecoexpoasia/en/travel-to-fairground-awePhoto download: https://bit.ly/48MjH8FThe 20th Eco Expo Asia, jointly organised by the Hong Kong Trade Development Council (HKTDC) and Messe Frankfurt (HK) Ltd, opened at AsiaWorld-Expo today and runs until 31 October, attracting some 340 exhibitors. Yu Huiwen, Vice Minister of the Ministry of Ecology and Environment of the People's Republic of China, Ding Zhijun, Deputy Director of the Department of Energy Conservation and Comprehensive Utilization, Ministry of Industry and Information Technology of the People’s Republic of China; Tse Chin-wan, Secretary for Environment and Ecology of the Hong Kong SAR Government; Sophia Chong, HKTDC Executive Director, and other honourable guests attended the opening ceremonyYu Huiwen, Vice Minister of the Ministry of Ecology and Environment of the People's Republic of China (third left), Tse Chin-wan, Secretary for Environment and Ecology of the Hong Kong SAR Government (third right), Sophia Chong, HKTDC Executive Director (second left), and other honourable guests visited the ExpoThe Hong Kong SAR Government has invited government officials and representatives of quasi-governmental organisations from Belt and Road countries and regions, including Cambodia, Myanmar and Sri Lanka, to attend the 20th Eco Expo AsiaThis year’s Expo brings together 17 pavilions. For the first time, the Environmental Campaign Committee is hosting a pavilion, presenting 22 local green start-upsKorea is a new pavilion from overseas, with a strong lineupGreen and Smart Mobility is a new zone that has been added this year, focusing on green transport solutions and productsIndustry newcomers, such as research institutions and start-ups, bring innovative green solutionsThe Eco Asia Conference gathers global officials, industry leaders and experts to exchange insights on environmental issuesWebsiteEco Expo Asia: www.ecoexpoasia.comMedia enquiriesPlease contact the HKTDC’s Communications and Public Affairs Department:Stanley SoTel: (852) 2584 4049Email: stanley.hp.so@hktdc.orgClayton Lauw Tel: (852) 2584 4472 Email: clayton.y.lauw@hktdc.orgThe HKTDC’s Media Room: http://mediaroom.hktdc.com/enAbout HKTDCThe Hong Kong Trade Development Council (HKTDC) is a statutory body established in 1966 to promote, assist and develop Hong Kong's trade. With over 50 offices globally, including 13 in the Chinese Mainland, the HKTDC promotes Hong Kong as a two-way global investment and business hub. The HKTDC organises international exhibitions, conferences and business missions to create business opportunities for companies, particularly small and medium-sized enterprises (SMEs), in the mainland and international markets. The HKTDC also provides up-to-date market insights and product information via research reports and digital news channels. For more information, please visit: www.hktdc.com/aboutus. About Messe FrankfurtThe Messe Frankfurt Group is one of the world’s leading trade fair, congress and event organisers with its own exhibition grounds. With a workforce of some 2,160 people at its headquarters in Frankfurt am Main and in 28 subsidiaries, it organises events around the world. Group sales in financial year 2022 were around €454 million. We serve our customers’ business interests efficiently within the framework of our Fairs & Events, Locations and Services business fields. One of Messe Frankfurt’s key strengths is its powerful and closely knit global sales network, which covers around 180 countries in all regions of the world. Our comprehensive range of services – both onsite and online – ensures that customers worldwide enjoy consistently high quality and flexibility when planning, organising and running their events. We are using our digital expertise to develop new business models. The wide range of services includes renting exhibition grounds, trade fair construction and marketing, personnel and food services. Sustainability is a central pillar of our corporate strategy. Here, we strike a healthy balance between ecological and economic interests, social responsibility and diversity.For more information, please visit our website at: www.messefrankfurt.com/sustainability. With its headquarters in Frankfurt am Main, the company is owned by the City of Frankfurt (60%) and the State of Hesse (40%). For more information, please visit our website at: www.messefrankfurt.com Copyright 2025 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

Rouyn-Noranda, Quebec--(ACN Newswire via SeaPRwire.com - October 28, 2025) - Radisson Mining Resources Inc. (TSXV: RDS) (OTCQX: RMRDF) ("Radisson" or the "Company") is pleased to announce assay results from fifteen new drill holes completed at its 100%-owned O'Brien Gold Project ("O'Brien" or the "Project") located in the Abitibi region of Québec. The fifteen holes represent step-outs below the existing geological model and the historic O'Brien Gold Mine and are part of an ongoing 140,000-metre drill program designed to test the overall scope of gold mineralization at the Project (see Radisson news release dated October 16, 2025). All holes intersected gold mineralization in characteristic quartz-sulphide-gold veins within alteration zones, and thirteen of the holes returned intercepts with grades and thicknesses consistent with the Project's existing mineral resources.Today's results include significant intercepts in three separate step-out locations (Figures 1 & 2), each of which has significance for the potential future growth of the Project's mineral resources. These are:Between Trends #1 and #2 at 1,000 Metres Vertical DepthOB-25-371W5 intersected 10.50 grams per tonne ("g/t") gold ("Au") over 6.5 metres, including 14.90 g/t Au over 1.5 metres and including 16.95 g/t Au over 1.0 metreOB-25-371W4 intersected 11.25 g/t Au over 2.5 metres, including 17.80 g/t Au over 1.5 metresOB-25-371W6 intersected 4.51 g/t Au over 9.0 metres, including 10.70 g/t Au over 1.5 metresBeneath the Historic "O'Brien Mine West" at 1,000 Metres Vertical Depth OB-25-376W1 intersected 9.16 g/t Au over 2.5 metres, including 14.70 g/t Au over 1.1 metresOB-25-376 intersected 8.05 g/t Au over 2.50 metres, including 15.75 g/t Au over 1.0 metreBeneath the Historic "O'Brien Mine" at 1,100 Metres Vertical DepthOB-24-337W11 intersected 7.00 g/t Au over 3.0 metres, including 12.60 g/t Au over 1.5 metres, and 13.00 g/t Au over 1.50 metresMatt Manson, President & CEO, commented: "Today's drill results illustrate the extension of classic, high-grade O'Brien gold mineralization across a broad front. We are reporting the first high-grade intercepts beneath the western portion of the historic mine, with drill hole OB-25-376W1 extending mineralization 160 metres below the former mine in this area. Drill hole OB-24-337W11 demonstrates continuity of high-grade mineralization below the main stope of the historic mine. Of particular note, drill holes OB-25-371W4 to W6 returned high-grade mineralization on the western edge of the deep extension of Trend #2, close to the observed extension of Trend #1 (Figures 1&2). This suggests that the apparent gap between these two trends is a function of drill coverage rather than geology, as we have suspected. Closing this gap with new drilling is a priority. With a fully-funded 140,000-metre drill program ongoing and an increase in rigs from the current four to an eventual eight, we are casting a wide net at O'Brien and seeing consistent success."Figure 1: Longitudinal Vertical Section and Plan View of Gold Vein Mineralization and Mineral Resources at the O'Brien Gold Project, with Today's Drill Holes IllustratedTo view an enhanced version of this graphic, please visit:https://images.newsfilecorp.com/files/10977/272164_3fafb92ae4c30b1d_002full.jpgNotes on Calculation of Drill Intercepts:The O'Brien Gold Project Mineral Resource Estimate effective May 6, 2025 ("MRE") utilizes a 2.20 g/t Au bottom cut-off, a US$2,000 gold price, a minimum mining width of 1.2 metres, and a 40 g/t Au upper cap on composites. Intercepts presented in Table 1 are calculated with a 3.00 g/t Au bottom cut-off. True widths, based on depth of intercept and drill hole inclination, are estimated to be 30-80% of core length. Table 2 presents additional drill intercepts calculated with a 1.00 g/t bottom cut-off over a minimum 1.0 metre core length so as to illustrate the frequency and continuity of mineralized intervals within which high-grade gold veins at O'Brien are developed. Lithology Codes: PON-S3: Pontiac Sediments; V3-S, V3-N, V3-CEN: Basalt-South, North, Central; S1P, S3P: Conglomerate; POR-S, POR-N: Porphyry South, North; TX: Crystal Tuff; ZFLLC: Larder Lake-Cadillac Fault Zone.Figure 2: Longitudinal Vertical Section of Gold Vein Mineralization and Mineral Resources at the O'Brien Gold Project, with Deep Step-Out Drill Holes Completed and/or Published by the Company since December 2024. To view an enhanced version of this graphic, please visit:https://images.newsfilecorp.com/files/10977/272164_3fafb92ae4c30b1d_004full.jpgGold Mineralization at O'BrienGold mineralizing quartz-sulphide veins at O'Brien occur within a thin band of interlayered mafic volcanic rocks, conglomerates, and porphyritic andesitic sills of the Piché Group occurring in contact with the east-west oriented Larder Lake-Cadillac Break ("LLCB"). Gold, along with pyrite and arsenopyrite, is typically associated with shearing and a pervasive biotite alteration, and developed within multiple Piché Group lithologies and, occasionally, the hanging-wall Pontiac and footwall Cadillac meta-sedimentary rocks.As mapped at the historic O'Brien mine, and now replicated in the modern drilling, individual veins are generally narrow, ranging from several centimetres up to several metres in thickness. Multiple veins occur sub-parallel to each other, as well as sub-parallel to the Piché lithologies and the LLCB. Individual veins have well-established lateral continuity, with near-vertical, high-grade shoots developed over significant lengths. Based on the historic data available, it is clear that the former mine was "high-graded", with mining focussed on a main central stope and parallel veins identified but left undeveloped.The historic O'Brien mine produced over half a million ounces of gold from such veins and shoots at an average grade exceeding 15 g/t Au and over a vertical extent of at least 1,000 metres. Modern exploration has focussed on delineating well developed vein mineralization to the east of the historic mine, with additional high-grade shoots becoming evident in the exploration data over what has been described as a series of repeating trends ("Trend #s 0 to 5").Step-Out Drilling at O'BrienSince the end of 2024, Radisson has been pursuing a program of broad step-outs beneath the historic O'Brien Gold mine and the existing mineral resources designed to test the extent of mineralization at the Project. This drilling is accomplished with pilot holes followed by wedges and directional drilling to maximize drill efficiency. On October 16, 2025 Radisson announced the expansion of the step-out drill program to 140,000 metres employing an eventual eight drill rigs.The origin of the step-out drill program was the deep pilot hole OB-24-337, which was the first exploration drill hole located below the former mine workings since mining ended in 1957. This hole intersected 31.24 g/t Au over 8.0 metres, including 242.0 g/t Au over 1.0 metre at approximately 1,500 metres vertical depth (see Radisson news release dated December 16, 2024). With today's results, assay results from a total of 11 wedges from OB-24-337 have now been reported and up to six gold-bearing veins have been delineated over an area of approximately 250 metres (east-west) by 500 metres (vertical). Included in today's results is the eleventh wedge, OB24-337-W11, which intersected 7.00 g/t Au over 3.0 metres, including 12.60 g/t Au over 1.5 metres, and 13.00 g/t Au over 1.50 metres approximately 100 metres below the final historic mining stope (Figure 1). This serves to demonstrate the continuity of mineralization from the former mine downwards towards the cluster previously published wedges (Figures 1 & 2; see Radisson news release dated July 16, 2025). Current drilling in this area is focussed on infilling with pilot holes and wedge extensions both above and below the OB-24-337 pattern of wedge branches to test the full continuity of mineralization from the historic mine down to 2 kilometres depth.Step-out drilling with wedge branches has also confirmed high-grade mineralization 170 metres below the base of the existing mineral resources at Trend #1 and 300 metres at Trend #2. These have included pilot hole OB-24-324, which intersected 27.61 g/t Au over 6.0 metres at Trend #1 (see Radisson news release dated October 30, 2024) and OB-24-363, which intersected 8.41 g/t Au over 2.20 metres, including 14.40 g/t Au over 1.20 metres and 9.07 g/t Au over 1.80 metres, including 12.10 g/t Au over 0.90 metres at Trend #2 (see Radisson news release dated September 8, 2025). Today's results include six wedges from drill hole OB-25-371, which demonstrate strongly developed, high-grade mineralization on the western edge of the deep extension of Trend #2. These holes include OB-25-371W5, which intersected 10.50 g/t Au over 6.5 metres, including 14.90 g/t Au over 1.5 metres and including 16.95 g/t Au over 1.0 metre (Figures 1&3). The significance of these holes is that the apparent separation of Trend #1 and Trend #2 is based, in part, on a data gap caused by drill rig access restrictions and a lack of drilling (Figure 2). Targeting this gap and testing for continuity of mineralization between Trends #1 and #2, as well as at depth, is a priority of the current drill program.Today's results also include the first drill holes located below the western portion of the historic O'Brien Gold Mine, designated "O'Brien Mine West". As with the main mining area, no exploration had been conducted below O'Brien Mine West since operations ended in 1957. From pilot hole OB-25-376 and wedge branches W1 to W5, five holes returned intercepts with grades and thicknesses consistent with the Project's mineral resources, including OB-25-376W1, which intersected 9.16 g/t Au over 2.5 metres, including 14.70 g/t Au over 1.1 metres (Figure 1). This now extends gold mineralization at O'Brien Mine West 160 metres below the base of the former mine workings (Figure 4).Figure 3: Vertical Cross Section through "Trend #2" with Drill Hole Wedges OB-25-371W2 to W6To view an enhanced version of this graphic, please visit:https://images.newsfilecorp.com/files/10977/272164_3fafb92ae4c30b1d_005full.jpg Figure 4: Vertical Cross Section through "O'Brien Mine West" with Drill Hole OB-25-376 and Wedges W1 to W5To view an enhanced version of this graphic, please visit:https://images.newsfilecorp.com/files/10977/272164_3fafb92ae4c30b1d_006full.jpgQA/QCAll drill cores in this campaign are NQ in size. Assays were completed on sawn half-cores, with the second half kept for future reference. The samples were analyzed using standard fire assay procedures with Atomic Absorption (AA) finish at ALS Laboratory Ltd, in Val-d'Or, Quebec. Samples yielding a grade higher than 10 g/t Au were analyzed a second time by fire assay with gravimetric finish at the same laboratory. Mineralized zones containing visible gold were analyzed with metallic sieve procedure. Standard reference materials, blank samples and duplicates were inserted prior to shipment for quality assurance and quality control (QA/QC) program.Qualified Persons Disclosure of a scientific or technical nature in this news release was prepared under the supervision of Mr. Richard Nieminen, P.Geo, (QC), a geological consultant for Radisson and a Qualified Person for purposes of NI 43-101. Mr. Luke Evans, M.Sc., P.Eng., ing, of SLR Consulting (Canada) Ltd., is the Qualified Person responsible for the preparation of the MRE at O'Brien. Each of Mr. Nieminen and Mr. Evans is independent of Radisson and the O'Brien Gold Project.About Radisson MiningRadisson is a gold exploration company focused on its 100% owned O'Brien Gold Project, located in the Bousquet-Cadillac mining camp along the world-renowned Larder-Lake-Cadillac Break in Abitibi, Québec. A July 2025 Preliminary Economic Assessment described a low cost and high value project with an 11-year mine life and significant upside potential based on the use of existing regional infrastructure. Indicated Mineral Resources are estimated at 0.58 million ounces (2.20 million tonnes at 8.2 g/t Au), with additional Inferred Mineral Resources estimated at 0.93 million ounces (6.67 million tonnes at 4.4 g/t Au). Please see the NI 43-101 "O'Brien Gold Project Technical Report and Preliminary Economic Assessment, Québec, Canada" effective June 27, 2025, and other filings made with Canadian securities regulatory authorities available at www.sedarplus.ca for further details and assumptions relating to the O'Brien Gold Project. For more information on Radisson, visit our website at www.radissonmining.com or contact:Matt MansonPresident and CEO416.618.5885mmanson@radissonmining.comKristina PillonManager, Investor Relations604.908.1695kpillon@radissonmining.comForward-Looking StatementsThis news release contains "forward-looking information" within the meaning of the applicable Canadian securities legislation that is based on expectations, estimates, projections, and interpretations as at the date of this news release. Forward-looking statements including, but are not limited to, statements with respect to the ability to execute the Company's plans relating to the O'Brien Gold Project as set out in the Preliminary Economic Assessment; the Company's ability to complete its planned exploration and development programs; the absence of adverse conditions at the O'Brien Gold Project; the absence of unforeseen operational delays; the absence of material delays in obtaining necessary permits; the price of gold remaining at levels that render the O'Brien Gold Project profitable; the Company's ability to continue raising necessary capital to finance its operations; the ability to realize on the mineral resource and mineral reserve estimates; assumptions regarding present and future business strategies; local and global geopolitical and economic conditions and the environment in which the Company operates and will operate in the future; planned and ongoing drilling; the significance of drill results; the ability to continue drilling; the impact of drilling on the definition of any resource; and the ability to incorporate new drilling in an updated technical report and resource modelling; the Company's ability to grow the O'Brien Gold Project; and the ability to convert inferred mineral resources to indicated mineral resources. Any statement that involves discussions with respect to predictions, expectations, interpretations, beliefs, plans, projections, objectives, assumptions, future events or performance (often but not always using phrases such as "expects", or "does not expect", "is expected", "interpreted", "management's view", "anticipates" or "does not anticipate", "plans", "budget", "scheduled", "forecasts", "estimates", "believes" or "intends" or variations of such words and phrases or stating that certain actions, events or results "may" or "could", "would", "might" or "will" be taken to occur or be achieved) are not statements of historical fact and may be forward-looking information and are intended to identify forward-looking information. Except for statements of historical fact relating to the Company, certain information contained herein constitutes forward-looking statements Forward-looking information is based on estimates of management of the Company, at the time it was made, involves known and unknown risks, uncertainties and other factors which may cause the actual results, performance or achievements of the companies to be materially different from any future results, performance or achievements expressed or implied by such forward-looking information. Such factors include, among others; the risk that the O'Brien Gold Project will never reach the production stage (including due to a lack of financing); the Company's capital requirements and access to funding; changes in legislation, regulations and accounting standards to which the Company is subject, including environmental, health and safety standards, and the impact of such legislation, regulations and standards on the Company's activities; price volatility and availability of commodities; instability in the global financial system; the effects of high inflation, such as higher commodity prices; the risk of any future litigation against the Company; changes in project parameters and/or economic assessments as plans continue to be refined; the risk that actual costs may exceed estimated costs; geological, mining and exploration technical problems; failure of plant, equipment or processes to operate as anticipated; accidents, labour disputes and other risks of the mining industry; delays in obtaining governmental approvals or financing; risks relating to the drill results at O'Brien; the significance of drill results; and the ability of drill results to accurately predict mineralization. Although the forward-looking information contained in this news release is based upon what management believes, or believed at the time, to be reasonable assumptions, the parties cannot assure shareholders and prospective purchasers of securities that actual results will be consistent with such forward-looking information, as there may be other factors that cause results not to be as anticipated, estimated or intended, and neither the Company nor any other person assumes responsibility for the accuracy and completeness of any such forward-looking information. The Company believes that this forward-looking information is based on reasonable assumptions, but no assurance can be given that these expectations will prove to be correct and such forward-looking statements included in this press release should not be unduly relied upon. The Company does not undertake, and assumes no obligation, to update or revise any such forward-looking statements or forward-looking information contained herein to reflect new events or circumstances, except as may be required by law. These statements speak only as of the date of this news release.Please refer to the "Risks and Uncertainties Related to Exploration" and the "Risks Related to Financing and Development" sections of the Company's Management's Discussion and Analysis dated April 29, 2025 for the year ended December 31, 2024, and the Company's Management's Discussion and Analysis dated August 27, 2025 for the three-month period ended June 30, 2025, all of which are available electronically on SEDAR+ at www.sedarplus.ca. All forward-looking statements contained in this press release are expressly qualified by this cautionary statement.Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this news release. No stock exchange, securities commission or other regulatory authority has approved or disapproved the information contained herein.To view the source version of this press release, please visit https://www.newsfilecorp.com/release/272164 Copyright 2025 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

深圳, 2025年10月27日 - (亞太商訊 via SeaPRwire.com) - 康哲藥業控股有限公司（「康哲藥業」）欣然宣佈，於2025年10月27日，康哲藥業通過子公司CMS VISION INTERNATIONAL MANAGEMENT LIMITED與Novartis Pharma Services AG （「諾華」）就雷珠單抗注射液（「諾適得(R)」）、布西珠單抗注射液（「倍優適(R)」）簽訂經銷協議（「協議」）。根據協議，康哲藥業獲得產品在中華人民共和國（為協議之目的，不含香港特別行政區、澳門特別行政區、台灣）的協議所約定之獨家進口、經銷、銷售、推廣權利；諾華繼續負責生產、供應產品。合作期限為協議約定的生效日起五年。兩款合作產品均已在中國獲批上市，其中諾適得(R)是中國首個獲批用於眼科的抗血管內皮生長因子（VEGF）藥物，具備成熟的臨床應用經驗，為眾多眼底疾病患者提供了可靠保障；諾適得(R)已被批准用於治療濕性年齡相關性黃斑變性（nAMD）、糖尿病性黃斑水腫(DME)、視網膜靜脈阻塞(RVO)繼發的黃斑水腫等多項眼底新生血管性疾病。另一款產品倍優適(R)為新一代抗VEGF藥物，2025年5月中國獲批用於DME，其憑藉獨特的超小分子（僅26kDa）、高濃度創新優勢，顯著改善視網膜解剖學結構，助力更多DME患者獲得視力改善，減輕治療負擔。康哲藥業眼科業務公司「康哲維盛」專注於在全球範圍內佈局、開發臨床急需的眼科藥械創新產品，致力於打造「中國眼科醫藥龍頭」，此次合作將提升康哲維盛在眼科領域的整體競爭力。康哲維盛已覆蓋眼底疾病、視疲勞、青光眼等眼科疾病領域，諾適得(R)及倍優適(R)加入後，將與在售獨家藥施圖倫滴眼液（七葉洋地黃雙苷滴眼液）、在售獨家醫療器械EyeOP1青光眼治療儀在客戶、專家資源、渠道網絡上產生高度協同，提升康哲維盛在眼科領域的學術品牌競爭力，為持續合作、開發臨床急需的眼科創新產品帶來正向推動作用，為眼科疾病患者提供更多元化的治療選擇。同時康哲維盛專業的眼科團隊將整合市場渠道與學術資源，提升團隊整體效能，並預期對康哲藥業業績產生積極正面影響。關於諾適得(R)及眼底新生血管性疾病的更多信息諾適得(R)是重組抗VEGF人源化單克隆抗體Fab片段，靶向抑制人血管內皮生長因子A（VEGF-A），以抑制血管內皮細胞增殖、新生血管生成和血管滲漏。諾適得(R)作為中國首個獲批用於眼科的抗VEGF藥物[3]，自2011年在中國上市以來，已被批准用於治療多項眼底新生血管性疾病，包括nAMD、DME、RVO繼發的黃斑水腫、脈絡膜新生血管(CNV)、糖尿病視網膜病變（DR）、早產兒視網膜病變(ROP)。諾適得(R)已於2017年被納入《國家基本醫療保險、工傷保險和生育保險藥品目錄》，具備成熟的臨床應用經驗，為眾多眼底疾病患者提供了可靠保障。眼底新生血管性疾病是一類以血管通透性增加、血管滲漏以及血管完整性的缺失為特徵的嚴重致盲性眼病，主要包括nAMD、DR、DME、RVO、CNV、ROP等。抗VEGF藥物是多個權威指南推薦治療眼底新生血管性疾病的一線療法[3, 4]。根據弗若斯特沙利文報告，中國眼底新生血管性疾病患者預計將從2019年的47.8百萬人增至2030年的61.2百萬人。中國抗VEGF眼科藥物市場預期將從2019年的24億元增長至2030年的186億元。根據《抗VEGF藥物治療眼底新生血管性疾病》，諾適得(R)作為中國首個獲批用於治療眼底新生血管性疾病的抗VEGF藥物，在多項臨床試驗中均顯示出良好的安全性和有效性，已被廣泛應用於治療眼底新生血管性疾病，它的問世代表了眼科臨床治療的一個重大進步[5]。關於倍優適(R)及DME適應症的更多信息倍優適(R)是一種靶向VEGF-A的新型人源化單鏈抗體片段，已於2025年5月獲得中國國家藥品監督管理局批准用於DME。作為目前分子量最小的抗VEGF藥物（僅26kDa），倍優適(R)治療DME負荷期每6周給藥一次（其他抗VEGF藥物負荷期每4周給藥1次），維持期每2至3個月給藥一次。倍優適(R)針對初治DME患者的全球3期KESTREL和KITE研究均達到主要療效終點且視力獲益持續至100周。倍優適(R)6mg組患者IRF（視網膜內積液）和/或SRF（視網膜下積液）更少。倍優適(R)首年中位注射次數（7次）少於阿柏西普（9次），同時總體安全性與後者相當[6]。中國真實世界研究BEST研究顯示，經治不達標的DME患者經倍優適(R)首針治療1周後BCVA即較基線提升6.1字母，注射第3針（12周）提升10字母，倍優適(R)為經治DME提供更優化的治療選擇[7]。DME是由於黃斑區毛細血管滲漏所致的視網膜增厚，是血視網膜屏障破壞的結果，主要影響中心視力[8]。據弗若斯特沙利文報告，2025年中國約有7.89百萬例DME患者。但即使按目前規範的抗VEGF藥物治療方案，仍有約30%-50%DME患者積液控制不佳[9-11]。《2022中國常見眼底病慢病管理現狀白皮書》調研顯示，我國患者治療依從性較差，30%以上DME患者未能完成負荷期治療。臨床亟需更強效、更持久、依從性更高的治療藥物以改善DME患者的診療現狀。新一代抗VEGF藥物倍優適(R)為解決這一難題提供了潛在方法，其憑藉獨特的超小分子、高濃度創新優勢，顯著改善視網膜解剖學結構，助力更多DME患者獲得視力改善，減輕治療負擔。關於諾華諾華是一家全球知名的醫藥企業，總部位於瑞士巴塞爾。諾華聚焦患者需求緊迫的四大核心治療領域（心血管、腎臟及代謝，腫瘤，免疫，神經科學）以及五大關鍵技術平台（化學療法、生物療法、xRNA療法、放射配體療法、基因和細胞療法）。關於康哲藥業康哲藥業是一家鏈接醫藥創新與商業化，把控產品全生命週期管理的開放式平台型企業，致力於提供有競爭力的產品和服務，滿足尚未滿足的醫療需求。康哲藥業專注於全球首創（FIC）及同類最優（BIC）的創新產品，並高效推進創新產品臨床研究開發和商業化進程，賦能科研成果向診療實踐的持續轉化，造福患者。康哲藥業聚焦專科領域，擁有被驗證的商業化能力，廣泛的渠道覆蓋和多疾病領域專家資源，核心在售產品已獲領先的學術與市場地位。康哲藥業圍繞優勢專科領域不斷縱深發展，以鞏固心腦血管/消化/眼科/皮膚健康業務競爭力，帶來專科規模效率，其中皮膚健康業務（德鎂醫藥）已成為其細分領域的龍頭企業，並擬於聯交所獨立上市。同時，康哲藥業持續推動研產銷全產業鏈在東南亞及中東區域運營發展，以獲取新興市場的增量，助力集團實現高質量可持續發展。參考文獻/資料1. 產品相關信息可在諾華官網查詢，網址：https://www.novartis.com.cn/news/big-news-noxtex-welcomes-the-approval-of-dual-indications2. Lim, Jennifer I et al. “Diabetic Retinopathy Preferred Practice Pattern(R).” Ophthalmology vol. 132,4 (2025): P75-P162. doi:10.1016/j.ophtha.2024.12.0203. 中華醫學會眼科學分會眼底病學組,中國醫師協會眼科醫師分會眼底病學組.中國年齡相關性黃斑變性臨床診療指南(2023年)[J].中華眼科雜誌,2023,59(5):347-366.4. 許迅,王建影.疾病譜變化驅動臨床藥物更迭[N].健康報,2023-07-05(005).5. 侯慧敏,常雪柯,靳雨佳,等.抗VEGF藥物治療眼底新生血管性疾病[J].國際眼科縱覽,2024,48(6):464-470.6. Wykoff CC, Garweg JG, Regillo C, et al. KESTREL and KITE Phase 3 Studies: 100-Week Results With Brolucizumab in Patients With Diaßbetic Macular Edema. Am J Ophthalmol. 2024;260:70-83.7. 餘洪華，2025中國眼底病論壇暨國際視網膜研討會，6月4日-7日，中國無錫8. 中華醫學會眼科學分會眼底病學組,中國醫師協會眼科醫師分會眼底病學組. 我國糖尿病視網膜病變臨床診療指南(2022年)[J]. 中華眼底病雜誌,2023,39(2):99-124.9. 戴虹, 盧穎毅. 糖尿病黃斑水腫治療策略的變化與面臨的問題[J].中華眼底病雜誌, 2022, 38(1): 6-9.10. Bressler, Neil M et al. “Persistent Macular Thickening Following Intravitreous Aflibercept, Bevacizumab, or Ranibizumab for Central-Involved Diabetic Macular Edema With Vision Impairment: A Secondary Analysis of a Randomized Clinical Trial.” JAMA ophthalmology vol. 136,3 (2018): 257-269.11. Chatziralli, I et al. “Identification of time point to best define 'sub-optimal response' following intravitreal ranibizumab therapy for diabetic macular edema based on real-life data.” Eye (London, England) vol. 31,11 (2017): 1594-1599.康哲藥業免責與前瞻性聲明本新聞無意向您做任何產品的推廣，非廣告用途。本新聞不對任何藥品和醫療器械和/或適應症作推薦。若您想瞭解具體疾病診療資訊，請遵從醫生或其他醫療衛生專業人士的意見或指導。醫療衛生專業人士作出的任何與治療有關的決定應根據患者的具體情況並遵照藥品說明書。由康哲藥業編制的此新聞不構成購買或認購任何證券的任何要約或邀請，不形成任何合約或任何其他約束性承諾的依據或加以依賴。本新聞由康哲藥業根據其認為可靠之資料及數據編制，但康哲藥業並無進行任何說明或保證、明述或暗示，或其他表述，對本新聞內容的真實性、準確性、完整性、公平性及合理性不應加以依賴。本新聞中討論的若干事宜可能包含涉及康哲藥業的市場機會及業務前景的陳述，該等陳述分別或統稱為前瞻性聲明。該等前瞻性聲明並非對未來表現的保證，存在已知及未知的風險、不明朗性及難以預知的假設。康哲藥業並不採納本新聞包含的第三方所做的任何前瞻性聲明及預測，康哲藥業對該等第三方聲明及預測不承擔責任。 Copyright 2025 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com

香港, 2025年10月28日 - (亞太商訊 via SeaPRwire.com) - 2025年10月28日，權威管理諮詢機構久謙諮詢發佈全球全景及運動相機市場研究報告。報告指出，近年全球運動相機與全景相機市場份額出現顯著變化，市場格局正經歷快速重構。在運動相機領域，曾經佔據全球主導地位的是美國品牌GoPro，2022-23年，GoPro依靠HERO系列穩居頭部，全球市場佔有率75%以上，但到2025年其收入佔全球市場份額已逐步收縮至18%。而經過三年，市場迎來"新王"——大疆憑藉多年戰略佈局、產品節奏及生態協同，快速崛起，到2025年Q3大疆在這個領域的收入佔全球市場份額已達66%，以絕對優勢成為全球運動相機市場第一。另一中國品牌影石目前則佔據約13%的市場份額。 全景相機的市場格局也迎來激烈變動。大疆於今年7月31日入局該領域，在不到三個月的時間內，其首款全景相機Osmo360，憑藉跨端應用與高性價比的優勢，分別在中國電商渠道獲得了49%的市場份額，全球市場份額達43%。加速推動全球全景相機市場格局重構。最近京東"運動相機金榜"出爐，也見證了整個運動相機賽道，已經徹底進入"大疆時間"。大疆Osmo Action 5 Pro、大疆Osmo Nano、大疆Osmo Action 4三款產品直接包攬運動相機金榜前三。從更詳細的市場表現上看，在京東"戶外全景運動相機熱賣榜"中，大疆Osmo 360發佈接近不到3個月也奪得榜首，且已經在此領域上佔據了49天的位置。大疆在運動相機和全景相機的市佔和銷量數據，不僅是中國品牌科技硬實力的證明，也顯示大疆在原來佔據絕對優勢的無人機行業之外，以持續成長的影像技術矩陣及生態佈局，在全球手持影像市場也取得了絕對優勢領跑的地位。 Copyright 2025 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com

香港, 2025年10月28日 - (亞太商訊 via SeaPRwire.com) - 2025年，整個冰激淩行業普遍處於謹慎和觀望的狀態，面對消費者需求的不斷變化，各家都在努力探索新的打法和方向。在這種充滿挑戰的局面下，作為行業領導者的蒙牛，卻率先找到了破局之道。上半年，憑藉一系列亮眼的產品和營銷創新，蒙牛的冰品業務交出了同比增長15%的優異答卷。這一增速，顯著超越了行業平均水平。考慮到七八月份，全國各地持續高溫，冰品消費熱度不減，市場對於蒙牛冰品在三季度乃至全年的業績增長也更添了幾分樂觀與期待。在現制茶飲跨界打劫、渠道日益碎片化的複雜局面下，一個深耕冰淇淋市場多年的傳統巨頭，為何能重拾增長動力，實現如此強勁的逆勢上揚？這背後，隱藏著一套怎樣的增長秘訣？ 經典為本+爆款不斷在快速消費品領域，一切商業邏輯的起點和終點，終究是產品本身。面對消費者需求的高度分化與迅速變換，蒙牛祭出了一套清晰而有力的組合拳，即所謂的「守正出奇」。所謂「守正」，是穩固基本盤。蒙牛將大量的核心資源聚焦於「隨變」與「綠色心情」兩大國民品牌，通過對經典大單品的持續優化，不斷夯實市場份額。數據顯示，整個上半年，兩大品牌的合計銷售佔比已穩步提升至55.2%，成為整個冰品業務最穩固的壓艙石，也奠定了全年業績增長的穩定基礎。而「出奇」，則是通過持續不斷地推出爆款新品，來製造新的增長勢能，點燃消費者對品牌的關注與熱情。如果說經典產品是蒙牛冰品這艘巨輪的船身，那麼爆款新品就是驅動它破浪前行的強大引擎。2025年上半年，蒙牛新上市了多款高品質、高質價比、高情緒價值的新品：無論是融合了經典懷舊造型的「隨變轉」，還是色彩繽紛、顏值出眾的「絢彩冰系列」，亦或是開闢了全新食用場景的「冰杯」，都成為了現象級的爆款，而一系列的奶冰產品更是備受消費者的青睞，新推出的鮮牛奶冰激淩系列、高端生牛乳冰激淩及活菌酸奶冰激淩，滿足了消費者對健康天然原料與美味的雙重需求。據統計，上半年共有9支新品強勢突破了千萬級銷量的門檻，新品整體銷售額佔比同比提升了2.7個百分點，創下歷史新高。除此之外，二三季度，蒙牛在杯裝產品上的持續發力，也讓線上線下的銷售熱度進一步攀升。這種「守正」與「出奇」的結合，展現出了一家老牌企業應有的戰略智慧：既有經典產品帶來的品牌信任與渠道忠誠度，又有爆款新品帶來的市場話題與增量用戶，二者共同構成了一個攻守兼備、富有韌性的產品矩陣組合。新興渠道與傳統渠道和諧共舞如果說產品是決定核心價值的1，那麼渠道就是1後面跟著的那一連串的0。面對近幾年線上流量持續分化、線下賣場客流下滑的嚴峻挑戰，蒙牛冰品的渠道策略完成了一次極為華麗的轉身——從過去的「廣度覆蓋」轉向了今年的全渠道全場景「深度運營」，而成功的關鍵，則是以一套多元化的產品組合，去精准適配不同渠道的用戶需求特點。這不再是簡單的「鋪貨」，而是一場新興渠道與傳統渠道協作共生的「雙人舞」。線上線下的新興渠道，已然成為業務增長最強勁的引擎。2025年上半年，新興渠道整體銷量猛增33%，其中生鮮電商的銷售增速更是超過40%，豆冰、水冰等品類全面超越競對，直營閃電倉的客單價實現了爆發性增長。這一系列的成績，證明了蒙牛對線上消費趨勢的敏銳捕捉和高效執行。而針對新興渠道的消費特點，蒙牛展現出了極強的策略適配能力。例如，今年借勢美團517吃貨節，蒙牛通過趣味內容植入美團外賣小哥形象，將媒介流量精准導向美團的銷售渠道，並聯動頭部便利店進行直播，實現了營銷動作與渠道銷售的無縫銜接，高效地放大了銷售效果。在傳統渠道，蒙牛同樣展現了強大的調整和適應能力。面對傳統商超賣場的人流量下滑，公司並未消極應對，而是主動出擊，將重心聚焦於校園、社區等高產出門店，通過提升冰櫃規模與專櫃管控，實現了大盤的穩定增長。在這個過程當中，蒙牛還通過引入一系列的數智化手段，成功的強化了對銷售終端的掌控力、優化了渠道的履約能力和運營效率。同時，為了尋找新的增長點，蒙牛大力開拓新賽道，積極發展會員店、零食量販店等新興零售業態，通過專供、聯名等模式打造渠道大單品，成功對沖了傳統商超渠道的流量挑戰。在定制業務方面，蒙牛的滲透同樣不遺餘力。通過積極拓展餐飲連鎖、熱門景區、交通樞紐等場景的覆蓋，產品得以觸達消費者生活的更多細微觸點，成功打造了多款基於不同場景的定制化產品，開拓銷售新增長點。除此之外，蒙牛的目光還投向了消費潛力更加廣闊的港澳台及海外市場。旗下高端品牌蒂蘭聖雪成功入駐香港市場，成為中國大陸首個獲批香港食環署牌照的冰淇淋品牌。這不僅是品質的證明，更是品牌破圈和高端佔位的一次關鍵落子。營銷的本質是情感共鳴在Z世代成為消費主力的今天，單純的功能性滿足，已經不足以贏得年輕人的青睞，能夠與消費者建立並維持長期的情感共鳴，才是一個消費類品牌真正的護城河。有鑑於此，蒙牛的營銷思路，已經逐漸超越了傳統的廣告投放，進化為「產品+內容+媒介+渠道」四位一體的高度整合，其最終目標，是要與年輕一代消費者建立深度、可持續的情感鏈接。為了實現這一目標，與國民級IP的聯名，就成為引爆新品勢能的快捷方式。「綠色心情紅豆雙皮奶」與國民熱劇《甄嬛傳》的聯動，以「一口紅豆雙皮奶，穿越到宮廷」的巧妙構思，迅速捕獲了年輕人的心，在直播首銷期就取得了非常好的銷售成績和話題熱度。而更深層次的打法，則是以場景驅動增長。蒙牛的營銷團隊一改過去的做法，不再被動地等待消費者的關注，而是主動地去創造和融入年輕人的生活場景，通過全年覆蓋11座城市的音樂節現場，將蒙牛品牌與潮流、自由的文化符號深度綁定，在年輕人當中了取得非常好的口碑和促銷效果，尤其是「把音樂節開去超市」的創意活動，更是在五四青年節期間沖上熱搜，成為微博熱門話題。在這一系列操作的背後，貫穿始終的是蒙牛對品牌年輕化戰略的堅定執行。通過一次次成功的破圈營銷，蒙牛不斷刷新著品牌在Z世代心中的形象。對於新一代的消費者，蒙牛不再僅僅是一個耳熟能詳的食品製造商，更是一個活躍在年輕人文化場景中的「玩伴」，是一個可以分享樂趣、有共同語言的夥伴。這樣的情感鏈接強度，已經遠遠超出了狹義的產品營銷範疇，而是成為新時代品效合一營銷思想的經典案例。整個二、三季度，蒙牛在線上的話題熱度和傳播效應，始終保持了極高的水平，也是對這一全新營銷思路的一次成功驗證。可持續的增長飛輪所有成功的戰略，最終都要回歸到財務數據的驗證。蒙牛冰品業務的價值，不僅在於當下令人矚目的高增長，更在於其增長邏輯的可持續性。從業績上看，上半年15%的同比增長，顯著跑贏了行業大盤，展示出了強大的增長潛力。更值得注意的是，冰品業務佔蒙牛總收入的比重從去年同期的7.5%提升至9.3%，對集團整體業績的貢獻度顯著增強，其戰略地位日益凸顯。從可持續性來看，當前的成績並非源於短期的市場刺激或單一的爆款效應，而是產品力、渠道力、營銷力三大戰略協同發力的必然結果。一個穩固的經典產品基本盤，一套能夠精准適配多元渠道的運營體系，一種能與新一代消費者同頻共振的品牌溝通能力，這三大支柱共同構建了蒙牛冰品業務面向未來的、可持續的增長飛輪。在消費者需求變化迅速、市場環境充滿挑戰的當下，蒙牛冰淇淋的逆勢增長，無疑為整個消費品行業提供了一個寶貴的範本：對於傳統快消領域的巨頭而言，只要能夠與時俱進，在產品、渠道、營銷等多個層面不斷自我革新，就依然能夠穿越週期，在龐大的現有基數之上，開啟更加令人期待的二次增長曲線。 Copyright 2025 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com

Oct 27, 2025 - (ACN Newswire via SeaPRwire.com) - The International Leo Tolstoy Peace Prize Jury announced the 2025 laureates in recognition of outstanding efforts contributing to regional harmony and security in Central Asia. The award honors the signing of the Treaty on the Junction Point of State Borders and the Khujand Declaration of Eternal Friendship in Khujand, Tajikistan, on March 31, 2025 — landmark agreements that strengthen legal frameworks for mutual trust and cross-border collaboration.Established on June 22, 2022, by the Russian Historical Society, the Russian Peace Foundation, and the Russian Military Historical Society, the International Leo Tolstoy Peace Prize Foundation convenes juries including prominent figures from Argentina, Belarus, India, China, Russia, France, South Africa, and Japan. Jury Chairman Valery Gergiev, renowned conductor and artistic director of the Mariinsky Theatre, emphasized the prize’s mission to “advance global understanding and mutual respect.” He noted the growing reach of the peace movement inspired by Russian writer-philosopher Leo Tolstoy, expressing hope that the prize could, like music, “help nations listen and truly hear one another.”The 2025 honor celebrates the joint efforts of:- Sadyr Japarov, Kyrgyz Republic- Emomali Rahmon, Republic of Tajikistan- Shavkat Mirziyoyev, Republic of UzbekistanTheir collaboration has strengthened stability, sustainable growth, and the international profile of Central Asia. The award ceremony date will be announced soon.About the PrizeThe International Leo Tolstoy Peace Prize is awarded by an international jury established by the founders of the L.N. Tolstoy International Peace Prize Foundation. The jury is composed of distinguished Russian and foreign figures of recognized international standing and moral authority.Candidates for the Prize may include individuals, initiative groups, national and international public foundations, organizations, movements, scientific and research centers, as well as educational institutions. Self-nomination is not permitted; however, nominators are encouraged to publicly discuss the candidates they propose. Rooted in the humanist ideals of Leo Tolstoy, the Prize honors those whose work embodies the pursuit of peace, moral integrity, and shared progress for humanity.Media contactOrganization: The International Leo Tolstoy Peace PrizeContact: Media teamWebsite: https://tolstoypeaceprize.org Copyright 2025 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

SHENZHEN, Oct 27, 2025 - (ACN Newswire via SeaPRwire.com) - China Medical System Holdings Limited (“CMS” or the “Group”) is pleased to announce that on 27 October 2025, the Group through its subsidiary CMS VISION INTERNATIONAL MANAGEMENT LIMITED entered into a Distribution Agreement (the “Agreement”) with Novartis Pharma Services AG (“Novartis”) for Ranibizumab Injection (“Lucentis®”) and Brolucizumab Injection (“Beovu®”). In accordance with the Agreement, the Group has obtained the exclusive right to import, distribute, sell and promote as specifically agreed upon in the Agreement in the People’s Republic of China (for the purpose of the Agreement, excluding the Hong Kong Special Administrative Region, the Macao Special Administrative Region and Taiwan) ; Novartis will continue to be responsible for the production and supply of the products. The term of cooperation comes into effect on the effective date of the Agreement and remains valid for a period of five years.Both collaborative products have been approved for marketing in China. Among them, Lucentis® is the first anti-vascular endothelial growth factor (VEGF) drug approved for ophthalmic use in China, and has accumulated mature clinical application experience, providing reliable support for numerous patients with ocular fundus diseases. Lucentis® has been approved for the treatment of multiple ocular neovascular diseases, including neovascular age-related macular degeneration (nAMD), diabetic macular edema (DME), macular edema following retinal vein occlusion (RVO), etc. Another product, Beovu®, is a next-generation anti-VEGF drug approved in China in May 2025 for the treatment of DME. Leveraging its innovative advantages of ultra-small molecular weight (only 26 kDa) and high concentration, Beovu® significantly improves retinal anatomical structure, helps more DME patients gain visual improvement, and alleviates treatment burden.The Group’s ophthalmology business company, “CMS Vision”, focuses on deploying and developing innovative ophthalmic pharmaceuticals and medical devices with urgent clinical needs on a global scale, striving to become a “leading ophthalmology pharmaceutical company in China”. This collaboration will enhance the overall competitiveness of CMS Vision in the field of ophthalmology. CMS Vision already covers ophthalmic disease areas such as fundus diseases, asthenopia and glaucoma. With the addition of Lucentis® and Beovu®, the portfolio will generate strong synergies with the marketed exclusive drug Augentropfen Stulln Mono Eye Drops (Esculin and Digitalisglycosides Eye Drops) and the marketed exclusive medical device EyeOP1 Glaucoma Treatment Device in terms of customer base, expert resources, and channel networks. This will further strengthen CMS Vision’s academic brand competitiveness in ophthalmology, provide positive momentum for sustained collaboration and the development of clinically needed innovative ophthalmic products, and offer patients more diverse treatment options. At the same time, CMS Vision’s professional ophthalmology team will integrate marketing channels and academic resources to improve the overall team efficiency. The collaboration is expected to have a positive impact on the Group’s financial results.More Information about LUCENTIS® and Ocular Neovascular DiseasesLucentis® is a recombinant humanized monoclonal antibody Fab fragment targeting VEGF. It targets and inhibits human vascular endothelial growth factor A (VEGF-A), thereby suppressing vascular endothelial cell proliferation, neovascularization, and vascular leakage. As the first anti-VEGF drug approved for ophthalmic use in China[3], Lucentis® has been approved for the treatment of multiple ocular neovascular diseases since its launch in China in 2011, including nAMD, DME, macular edema following RVO, choroidal neovascularization (CNV), diabetic retinopathy (DR), and retinopathy of prematurity (ROP). In 2017, Lucentis® was included in the National Reimbursement Drug List (NRDL) for Basic Medical Insurance, Work-Related Injury Insurance, and Maternity Insurance. It has accumulated mature clinical application experience, providing reliable support for numerous patients with ocular fundus diseases.Ocular neovascular diseases are a group of severe blinding ophthalmic conditions characterized by increased vascular permeability, vascular leakage, and loss of vascular integrity, mainly including nAMD, DR, DME, RVO, CNV, ROP, etc. Anti-VEGF drugs are recommended as first-line therapy for ocular neovascular diseases in multiple authoritative guidelines[3, 4]. According to a Frost & Sullivan report, the number of patients with ocular neovascular diseases in China is projected to increase from 47.8 million in 2019 to 61.2 million in 2030. The Chinese ophthalmic anti-VEGF drug market is expected to grow from RMB 2.4 billion in 2019 to RMB 18.6 billion in 2030. As stated in Anti-VEGF Drugs for Fundus Neovascular Diseases, Lucentis®—the first anti-VEGF drug approved for the treatment of ocular neovascular diseases in China—has demonstrated favorable safety and efficacy in multiple clinical trials. It has been widely used in the treatment of ocular neovascular diseases, and its launch represents a major advancement in clinical ophthalmic treatment[5].More Information about BEOVU® and the DME IndicationBeovu® is a novel VEGF-A-targeted humanized single-chain antibody fragment. It received approval from the National Medical Products Administration of China (NMPA) in May 2025 for the treatment of DME. As the current anti-VEGF drug with the smallest molecular weight (only 26 kDa), Beovu® is administered once every 6 weeks during the loading phase of the DME treatment (compared to once every 4 weeks for other anti-VEGF drugs) and once every two to three months during the maintenance phase. In the global Phase 3 KESTREL and KITE Studies for treatment-naive DME patients, Beovu® met all primary efficacy endpoints and the visual benefit persisted until Week 100. Additionally, patients in the Beovu® 6mg group had less intraretinal fluid (IRF) and/or subretinal fluid (SRF). The median number of injections of Beovu® in the first year (7 times) was lower than that of aflibercept (9 times), while its overall safety profile was comparable to the latter[6]. Data from the Chinese real-world study (BEST Study) showed that for previously treated and inadequately controlled DME patients, BCVA improved by 6.1 letters from baseline 1 week after the first injection of Beovu®, and by 10 letters after the third injection (Week 12). Beovu® provides a more optimized treatment option for previously treated DME patients[7].DME is a retinal thickening caused by capillary leakage in the macular area, which is the result of the breakdown of the blood retinal barrier and mainly affects central vision.[8]. According to a Frost & Sullivan report, there are approximately 7.89 million DME patients in China in 2025. However, even with the current standard anti-VEGF regimens, approximately 30%-50% of DME patients still exhibit suboptimal fluid control[9-11]. A survey in the 2022 White Paper on the Current Status of Chronic Disease Management for Common Ocular Fundus Diseases in China showed that treatment adherence among Chinese patients is relatively poor, with over 30% of DME patients failing to complete the loading phase treatment. There is an urgent clinical need for more potent, longer-lasting, and more adherence-friendly treatment options to improve the diagnosis and treatment of DME patients. As a next-generation anti-VEGF drug, Beovu® offers a potential solution to this challenge. Leveraging its innovative advantages of ultra-small molecular weight and high concentration, Beovu® significantly improves retinal anatomical structure, helps more DME patients gain visual improvement, and alleviates treatment burden.About NOVARTISNovartis is a globally renowned pharmaceutical company headquartered in Basel, Switzerland. The company focuses on four core therapeutic areas with urgent patient needs—Cardiovascular, Renal and Metabolic Disease, Oncology, Immunology, and Neuroscience—as well as five key technology platforms: Chemotherapy, Biotherapy, xRNA, Radioligand Therapy, and Gene and Cell Therapy.About CMSCMS is a platform company linking pharmaceutical innovation and commercialization with strong product lifecycle management capability, dedicated to providing competitive products and services to meet unmet medical needs.CMS focuses on the global first-in-class (FIC) and best-in-class (BIC) innovative products, and efficiently promotes the clinical research, development and commercialization of innovative products, enabling the continuous transformation of scientific research into clinical practices to benefit patients.CMS deeply engages in several specialty therapeutic fields, and has developed proven commercialization capabilities, extensive networks and expert resources, resulting in leading academic and market positions for its major marketed products. CMS continues to promote the in-depth development in its advantageous specialty fields, strengthening the competitiveness of the cardio-cerebrovascular/ gastroenterology/ ophthalmology/ skin health businesses, bringing economies of scale in specialty fields. Among them, the skin health business (Dermavon) has become a leading enterprise in its field, and is proposed to be listed independently on the SEHK. Meanwhile, CMS continuously promotes the operation and development of its integrated R&D, manufacturing and commercialization chain in Southeast Asia and the Middle East, capturing growth opportunities in emerging markets to support the high-quality and sustainable development of the Group. Reference:1. Product-related information can be found on the Novartis website at:https://www.novartis.com.cn/news/big-news-noxtex-welcomes-the-approval-of-dual-indications 2. Lim, Jennifer I et al. “Diabetic Retinopathy Preferred Practice Pattern®.” Ophthalmology vol. 132,4 (2025): P75-P162. doi:10.1016/j.ophtha.2024.12.0203. Chinese Vitreo-Retina Society of Chinese Medical Association, Fundus Disease Group of Chinese Ophthalmologist Association. Evidence-based guidelines for diagnosis and treatment of age-related macular degeneration in China(2023)[J]. Chinese Journal of Ophthalmology,2023,59(5):347-366. 4. Xu Xun, Wang Jianying. Changes in Disease Spectrum Drive the Evolution of Clinical Medications [N]. Health News, 2023-07-05(005).5. Hou Huimin, et al. Anti-VEGF drugs for fundus neovascular diseases[J].International Review of Ophthalmology,2024,48(6):464-470.6. Wykoff CC, Garweg JG, Regillo C, et al. KESTREL and KITE Phase 3 Studies: 100-Week Results With Brolucizumab in Patients With Diabetic Macular Edema. Am J Ophthalmol. 2024;260:70-83.7. Honghua Yu, 2025 China Forum on Fundus Diseases & International Retina Symposium, June 4-7, Wuxi, China.8. Chinese Vitreo-Retina Society of Chinese Medical Association, Fundus Disease Group of Chinese Ophthalmologist Association. Evidence-based guidelines for diagnosis and treatment of diabetic retinopathy in China (2022)[J]. Chinese Journal of Ocular Fundus Diseases,2023,39(2):99-124.9. Dai Hong, et al. Advances in the treatment strategies of diabetic macular edema and the problems[J]. Chinese Journal of Ocular Fundus Diseases,2022, 38(1): 6-9.10. Bressler, Neil M et al. “Persistent Macular Thickening Following Intravitreous Aflibercept, Bevacizumab, or Ranibizumab for Central-Involved Diabetic Macular Edema With Vision Impairment: A Secondary Analysis of a Randomized Clinical Trial.” JAMA ophthalmology vol. 136,3 (2018): 257-269.11. Chatziralli, I et al. “Identification of time point to best define 'sub-optimal response' following intravitreal ranibizumab therapy for diabetic macular edema based on real-life data.” Eye (London, England) vol. 31,11 (2017): 1594-1599.CMS Disclaimer and Forward-Looking StatementsThis press release is not intended to promote any products to you and is not for advertising purposes. This press release does not recommend any drugs, medical devices and/or indications. If you want to know more about the diagnosis and treatment of specific diseases, please follow the opinions or guidance of your doctor or other medical and health professionals. Any treatment-related decisions made by healthcare professionals should be based on the patient’s specific circumstances and in accordance with the drug package insert.This press release which has been prepared by CMS does not constitute any offer or invitation to purchase or subscribe for any securities, and shall not form the basis for or be relied on in connection with any contract or binding commitment whatsoever. This press release has been prepared by CMS based on information and data which it considers reliable, but CMS makes no representation or warranty, express or implied, whatsoever, and no reliance shall be placed on, the truth, accuracy, completeness, fairness and reasonableness of the contents of this press release. Certain matters discussed in this press release may contain statements regarding the Group’s market opportunity and business prospects that are individually and collectively forward-looking statements. Such forward-looking statements are not guarantees of future performance and are subject to known and unknown risks, uncertainties and assumptions that are difficult to predict. Any forward-looking statements and projections made by third parties included in this press release are not adopted by the Group and the Company is not responsible for such third-party statements and projections.Media ContactBrand: China Medical System Holdings Ltd.Contact: CMS Investor RelationsEmail: ir@cms.net.cnWebsite: https://web.cms.net.cn/en/home/ Copyright 2025 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

馬薩諸塞州特克斯伯里, 2025年10月27日 - (亞太商訊 via SeaPRwire.com) - CIL 的全球製造網絡遍佈北美、歐洲與亞洲，使公司能為製藥合作夥伴提供多元且具韌性的供應鏈。每一項 ISOAPI-D 產品皆於通過 ISO 9001 認證的設施中製造，確保在整個生產流程中達到最高的品質標準、法規遵循與完整的可追溯性。ISOAPI-DISOAPI-D Power of Deuterium: Smarter, Stronger TherapeuticsISOAPI-D 系列的核心組成之一為重水（D₂O），該原料僅由經核准的供應商提供。此產品具完整追溯性且不含氚（tritium），符合製藥產業嚴格的安全與法規要求。ISOAPI-D 系列同樣包含先進的中間體，可使合成途徑更加簡化。透過減少合成步驟並優化生產效率，這些中間體有助於降低製造成本，並加速新療法的上市進程。自 1981 年以來，CIL 一直是全球領先製藥與生物技術公司的優質去氘材料可信賴供應商。隨著 ISOAPI-D 的推出，CIL 將這份對品質與可靠性的長期承諾持續延伸，為客戶提供安全、高品質的關鍵試劑供應，並在研發流程中降低營運風險。CIL 去氘試劑應用業務開發經理 Tasha Agreste 表示：「ISOAPI-D 代表了我們持續推動製藥創新的下一步。我們擴展的製造能力、嚴謹的品質標準，以及數十年的專業經驗，使 CIL 成為能滿足業界不斷演變需求的可靠夥伴。」請於 10 月 28 日至 30 日蒞臨法蘭克福國際製藥原料展（CPhI Frankfurt）CIL 展位 #2.0G2，探索 ISOAPI-D —— 去氘化學推動製藥創新的未來。關於Cambridge Isotope Laboratories, Inc.CIL 為日本大塚製藥旗下子公司，是全球最大之穩定同位素及其標記化合物的製造商與供應商。自 1980 年以來，CIL 一直深受業界與學術界合作夥伴信賴，其產品廣泛應用於科研、診斷、環境監測、製藥、醫學檢測、OLED 與工業領域。CIL 的營運據點包括美國麻薩諸塞州波士頓地區的兩座設施、位於俄亥俄州錫尼亞（Xenia, OH）的大型同位素濃縮生產廠，以及 CIL 中國、CIL 加拿大、位於德國德勒斯登的 ABX（專門從事放射性同位素標記化合物，用於癌症診斷與治療），以及位於法國薩克雷（Saclay）的 Eurisotop。聯絡資訊Crissy Kriskocrissyk@isotope.com1.978.269.1930來源: Cambridge Isotope Laboratories, Inc. Copyright 2025 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com

TEWKSBURY, MA, Oct 27, 2025 - (ACN Newswire via SeaPRwire.com) - Cambridge Isotope Laboratories, Inc. (CIL), a global leader in stable isotope chemistry, announces the launch of ISOAPI-D™, a unified brand of deuterated intermediates for API synthesis. The new ISOAPI-D brand will be launched at CPhI Frankfurt, where CIL welcomes industry professionals to stand #2.0G2 from October 28-30.ISOAPI-DISOAPI-D Power of Deuterium: Smarter, Stronger Therapeutics"ISOAPI-D reagents are designed to support the development of next-generation active pharmaceutical ingredients (APIs) by leveraging the unique benefits of deuterium incorporation," said Cliff Caldwell, CEO of CIL. "With ISOAPI-D, our customers gain access to a trusted and secure supply chain, ensuring they have consistent, reliable access to the materials they need for robust and efficient drug development."CIL's global manufacturing network, including facilities in North America, Europe, and Asia, enables CIL to provide a diversified and resilient supply chain for pharmaceutical partners. Every ISOAPI-D product is manufactured in ISO 9001-certified facilities, ensuring the highest standards of quality, regulatory compliance, and full traceability throughout the production process.A core component of the ISOAPI-D line is heavy water (D₂O), which is sourced exclusively from approved suppliers. This product is fully traceable and tritium-free, aligning with stringent safety and regulatory requirements of the pharmaceutical industry.The ISOAPI-D range also features advanced intermediates that allow for more streamlined synthetic pathways. By reducing the number of synthesis steps and optimizing production efficiency, these intermediates can help lower manufacturing costs and accelerate the time to market for new therapeutics.Since 1981, CIL has been a trusted supplier of premium deuterated materials to leading pharmaceutical and biotechnology companies worldwide. This longstanding commitment to quality and reliability continues with the launch of ISOAPI-D, offering customers a secure, high-quality supply of essential reagents and reducing operational risk in their development pipelines."ISOAPI-D represents the next step in our ongoing mission to support pharmaceutical innovation," said Tasha Agreste, Business Development Manager Deuterated Reagent Applications, at CIL. "Our expanded manufacturing capabilities, rigorous quality standards, and decades of experience position CIL as a reliable partner for the industry's evolving needs."Visit CIL at CPhI Frankfurt, Stand #2.0G2, October 28-30, to discover ISOAPI-D, the future of deuterated chemistry for pharmaceuticals.About Cambridge Isotope Laboratories, Inc.CIL, a subsidiary of Otsuka Pharmaceutical in Japan, is the largest manufacturer and global supplier in the world of stable isotopes and stable isotope‑labeled compounds.Trusted by industrial and academic collaborators since 1980, CIL's products are used in research, diagnostics, environmental, pharmaceutical, medical diagnostic, OLED, and industrial applications. CIL's operations include two facilities in the Boston, MA, area; a large isotope‑enrichment production plant in Xenia, OH; CIL China; CIL Canada; ABX in Dresden, Germany (specializing in radioisotopic‑labeled compounds for cancer diagnosis and treatment); and Eurisotop in Saclay, France.Contact InformationCrissy Kriskocrissyk@isotope.com1.978.269.1930SOURCE: Cambridge Isotope Laboratories, Inc. Copyright 2025 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

麻薩諸塞州特克斯伯里與印度海德拉巴, 2025年10月27日 - (亞太商訊 via SeaPRwire.com) - Cambridge Isotope Laboratories, Inc.，(簡稱 CIL) 與手性與特種化學解決方案領導企業 Chemtatva Chiral Solutions 私人有限公司（Chemtatva Chiral Solutions, Pvt. Ltd.，簡稱 CCS）宣布已簽署諒解備忘錄，共同在印度海得拉巴（Hyderabad）成立Cambridge Isotope Laboratories, Pvt. Ltd.。此項舉措標誌著 CIL 全球版圖擴張的重要里程碑，並進一步強化其在去氘試劑及其他同位素富集產品開發與生產方面的能力。此合作將強化全球供應鏈韌性，為亞洲客戶提供即時支援，並實現多地點生產，確保全球客戶的業務持續運作。預計新實體 Cambridge Isotope Laboratories, Pvt. Ltd.將於 2025 年第 4 季正式成立，具體時程取決於常規盡職調查與交割流程。新公司的初期運營將在 CCS 現有設施中展開，並計劃於 2026 年啟動新廠建設。新設施將座落於印度海得拉巴郊區、佔地 2,000 英畝、快速成長的生命科學園區—— 基因谷（Genome Valley）。CIL 執行長 Cliff Caldwell 表示：「我們非常高興能與 CCS 攜手合作，結合雙方的化學專業，共同推進擴量技術的應用，以進一步支援製藥與工業領域的發展。這一舉措充分體現了我們對全球科研與研發工作的承諾，同時滿足製藥與電子產業對去氘標記與特種化學產品日益增長的商業需求。」CCS 執行長 Vishal Rajput 表示：「此次合作與新成立的公司將充分發揮 CCS 在印度強大的基礎設施與深厚的技術實力，同時結合 CIL 在同位素化學、品質系統、全球物流及市場推廣等方面的世界級標準。」Rajput 先生將擔任新成立之 Cambridge Isotope Laboratories, Pvt. Ltd. 的總經理。原有的 CCS 業務將保持獨立運作，雙方的共同目標是擴大全球客戶對高品質同位素標記及非標記化合物的獲取，特別聚焦於下游合成化合物的應用，並堅守各產業特定的產品品質要求。CIL、Eurisotop 與 CCS 所有品牌及製造的產品仍將透過現有渠道供應印度及全球客戶。關於 Cambridge Isotope Labs Pvt. Ltd. 的正式啟動及營運範圍，更多細節將於未來數月內公布。關於Cambridge Isotope Laboratories, Inc.CIL 為日本大塚製藥旗下子公司，是全球最大之穩定同位素及其標記化合物的製造商與供應商。自 1980 年以來，CIL 一直深受業界與學術界合作夥伴信賴，其產品廣泛應用於科研、診斷、環境監測、製藥、醫學檢測、OLED 與工業領域。CIL 的營運據點包括美國麻薩諸塞州波士頓地區的兩座設施、位於俄亥俄州錫尼亞（Xenia, OH）的大型同位素濃縮生產廠，以及 CIL 中國、CIL 加拿大、位於德國德勒斯登的 ABX（專門從事放射性同位素標記化合物，用於癌症診斷與治療），以及位於法國薩克雷（Saclay）的 Eurisotop。關於Chemtatva Chiral Solutions, Pvt. Ltd.CCS 成立於 2021 年，總部位於印度海得拉巴（Hyderabad），專精於手性化學、製程開發與客製化合成，服務對象涵蓋製藥及化學產業。作為生命科學領域值得信賴的全球合作夥伴，CCS 致力於提供創新的化學解決方案，以解決複雜挑戰並加速科學進步。聯絡資訊Crissy Kriskocrissyk@isotope.com1.978.269.1930來源: Cambridge Isotope Laboratories, Inc. Copyright 2025 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com

TEWKSBURY, MA AND HYDERABAD, INDIA, Oct 27, 2025 - (ACN Newswire via SeaPRwire.com) - Cambridge Isotope Laboratories, Inc. (CIL), and Chemtatva Chiral Solutions, Pvt. Ltd. (CCS), a leading provider of chiral and specialty chemical solutions, announce the execution of a signed Memorandum of Understanding to establish Cambridge Isotope Laboratories, Pvt. Ltd. in Hyderabad, India. This initiative marks a milestone in the expansion of CIL's global footprint and further enhances capabilities in the development and production of deuterated reagents and other isotopically enriched products. This partnership will enhance global supply chain strength and real-time support for customers in Asia and enable multi-site production for global customers focused on business continuity. The forthcoming entity, Cambridge Isotope Laboratories, Pvt. Ltd., is expected to be officially established in Q4 2025, subject to customary diligence and closing considerations. Operations for the newly formed entity will be initiated at existing CCS facilities, with a net new facility slated for groundbreaking in 2026. The new facility will be located in India's Genome Valley, a burgeoning 2,000-acre life sciences cluster located in suburban Hyderabad.Cliff Caldwell, CEO at CIL noted, "We are excited to partner with CCS to combine our chemistry expertise and pursue scale-up technologies to further support pharmaceutical and industrial applications. This initiative reflects our commitment to supporting global research and development efforts in scientific fields as well as supporting the growing commercial needs for deuterium labeled and specialty chemical products in the pharmaceutical and electronics industries."Vishal Rajput, CEO of CCS said, "The collaboration and newly formed entity will leverage CCS's strong infrastructure and deep technical capabilities in India, while integrating CIL's world-class standards in isotope chemistry, quality systems, global logistics and go-to market capabilities." Mr. Rajput will lead the newly formed entity as general manager of Cambridge Isotope Laboratories, Pvt. Ltd. The legacy CCS business will remain intact, with the collective intent to expand access to high quality, isotopically labeled and unlabeled compounds for customers worldwide, with an emphasis on downstream synthetic compounds and a commitment to industry-specific product quality requirements.All CIL, Eurisotop and CCS branded and manufactured materials remain available to Indian and worldwide customers through existing channels. Further details regarding the launch and operational scope of Cambridge Isotope Labs Pvt. Ltd. will be shared in the coming months.About Cambridge Isotope Laboratories, Inc.CIL, a subsidiary of Otsuka Pharmaceutical in Japan, is the largest manufacturer and global supplier in the world of stable isotopes and stable isotope‑labeled compounds. Trusted by industrial and academic collaborators since 1980, CIL's products are used in research, diagnostics, environmental, pharmaceutical, medical diagnostic, OLED, and industrial applications. CIL's operations include two facilities in the Boston, MA, area; a large isotope‑enrichment production plant in Xenia, OH; CIL China; CIL Canada; ABX in Dresden, Germany (specializing in radioisotopic‑labeled compounds for cancer diagnosis and treatment); and Eurisotop in Saclay, France.About Chemtatva Chiral Solutions, Pvt. Ltd.CCS is a Hyderabad-based company founded in 2021, specializing in chiral chemistry, process development, and custom synthesis for pharmaceutical and chemical industries. CCS is a trusted global partner in life sciences, delivering innovative chemistry solutions that solve complex challenges and accelerate scientific progress.Contact InformationCrissy Kriskocrissyk@isotope.com1.978.269.1930SOURCE: Cambridge Isotope Laboratories, Inc. Copyright 2025 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

香港, 2025年10月27日 - (亞太商訊 via SeaPRwire.com) - 周大福人壽今日宣佈，與港怡醫院、香港中文大學醫院（「中大醫院」）及香港浸信會醫院（「浸會醫院」）簽署合作備忘錄，建立策略性合作夥伴關係。周大福人壽更成為首間保險公司與港怡醫院其位於金鐘之日間醫療中心合作推出專屬計劃，為客戶提供健康管理方案。同時，「尚逸醫生網絡」全面升級，三家醫院及其附屬醫療中心正式加入，組成更強大的醫療網絡，覆蓋全港，為客戶提供優先轉介、預約及直接結算服務。周大福人壽執行董事兼行政總裁葉文傑表示：「我們非常高興與三家具領導地位的卓越醫院建立長遠合作關係，透過周大福集團生態圈的優勢，為客戶提供更靈活和優質的醫療服務方案，成為他們的人生規劃師 。是次合作不僅進一步鞏固我們全港的醫療網絡，同時亦進一步提升了周大福人壽的服務質量，讓客戶在不同人生階段，能享有更自主、便捷和全面的醫療服務體驗。我們堅信，醫療保障不應止於理賠，應延伸至預防、診斷、治療及康復的每一個階段，真正實踐開創健康新價值。」三區醫療網絡佈局 實現全港覆蓋三家醫院將分別成為周大福人壽於港島、九龍、新界區的指定醫療網絡，醫院醫生及心理健康治療師亦會加入「尚逸醫生網絡」，為客戶提供便捷、優質和全面的醫療服務。港島區：港怡醫院港怡醫院是港島區的指定醫療網絡。為進一步擴展服務範疇，周大福人壽更成為首間保險公司與港怡醫院位於金鐘、新開幕之港怡日間醫療中心合作，推出涵蓋「腸胃鏡檢查」及「疣切除」的專屬計劃，為客戶提供以預防為本的健康管理方案。新界區：中大醫院中大醫院將成為新界區的指定醫療網絡。中大醫院擁有由中大醫學院教授及專科醫生組成的頂尖醫護團隊，再配合其先進的醫療設施與科研實力，為客戶提供涵蓋多個專科的高端醫療服務。醫院致力將國際前沿醫研成果轉化為臨床服務，為客戶帶來世界級的診療體驗，惠及社會大眾。九龍區：浸會醫院浸會醫院將成為九龍區的指定醫療網絡。浸會醫院採用「一院多點」的營運模式，讓客戶能夠就近獲得所需醫療服務。其中，位於觀塘商貿區（牛頭角）的浸信會東九龍醫療中心（EKMC）提供白內障手術及腫瘤科預先批核直付服務; 其心理健康治療師團隊亦會為客戶提供身心靈全方位的照顧，秉持著「全人醫治．榮神益人」的精神。客戶專屬醫療服務 體現以人為本精神透過是次合作，三家醫院將為周大福人壽客戶提供以下服務：- 優先轉介及預約安排，大幅縮短輪候時間- 直接結算服務，客戶無需預先墊支醫療費用，減輕財務壓力- 一站式癌症治療服務，涵蓋診斷、治療、及術後康復，全程支援照顧- 高端醫療對接，為尊貴客戶安排教授級醫生及先進醫療設施，確保最優質的醫療照顧周大福人壽執行董事兼行政總裁葉文傑 (中) 、周大福人壽執行董事兼副行政總裁暨首席財務官徐志堅(右二) 、IHH醫療 (北亞洲) 區域首席執行官兼港怡醫院執行總裁曾慶亷醫生(左二)、香港中文大學醫院行政總裁鍾健禮醫生(右一) 以及香港浸信會醫院行政總監梁誌邦醫生(左一) 出席啟動禮，宣佈周大福人壽與三大醫院建立策略性合作夥伴關係。關於周大福人壽周大福人壽保險有限公司（「周大福人壽」）扎根香港40年，為周大福創建有限公司（「周大福創建」）（香港股份代號：659）的全資附屬公司，也是香港最具規模的壽險公司之一。作為周大福企業成員，周大福人壽緊扣鄭氏家族（「周大福集團」或「集團」）生態圈的雄厚資源，致力為客戶及其摯愛於「生活、成長、健康、傳承」的人生旅程中，提供個人化的匠心規劃、終身保障及優質體驗。憑藉集團財務實力及環球投資佈局，周大福人壽矢志成為亞太區領先的保險公司，持續開創保險新價值。傳媒聯絡周大福人壽企業傳訊部柳麗鳳+852 2591 8297vecinia.lau@ctflife.com.hk周大福人壽保險有限公司（於百慕達註冊成立之有限公司） Copyright 2025 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com

HONG KONG, Oct 27, 2025 - (ACN Newswire via SeaPRwire.com) – CTF Life today announced the signing of a Memorandum of Understanding with Gleneagles Hospital Hong Kong (“Gleneagles”), CUHK Medical Centre (“CUHKMC”), and Hong Kong Baptist Hospital (“HKBH”) to establish strategic partnerships. In a pioneering move, CTF Life has also become the first insurance company to collaborate with Gleneagles MediCentre in Admiralty to launch an exclusive programme to provide customers with health management solutions. At the same time, the PrimeChamp Doctor Network has been enhanced with the official inclusion of the three hospitals and their affiliated medical centres. This expanded medical network now spans across Hong Kong, offering customers priority referrals, appointment scheduling and direct billing services.Man Kit Ip, Executive Director and Chief Executive Officer of CTF Life, said, “We are pleased to forge long-term business partnerships with three leading and distinguished hospitals. Harnessing the strengths of the Chow Tai Fook Group ecosystem, we are committed to providing our customers with more flexible and superior medical service solutions, serving as their Life Planner. This collaboration not only further solidifies our medical network across Hong Kong, but also elevates the overall service experience at CTF Life, empowering customers with greater autonomy, convenience and comprehensive medical service experiences at every stage of their life journey. We firmly believe that medical protection should go beyond claims, it should accompany our customers across every stage from prevention and diagnosis to treatment and recovery, truly bringing to life our vision of creating value beyond healthcare.”Territory-wide Medical Network Coverage Across Hong KongThe three hospitals will respectively serve as CTF Life’s designated medical network partners on Hong Kong Island, Kowloon, and the New Territories. Their doctors and mental health therapists will also join the PrimeChamp Doctor Network, providing customers with convenient, high-quality, and comprehensive medical services.Hong Kong Island: Gleneagles Hospital Hong KongGleneagles serves as the appointed medical network partner for Hong Kong Island. CTF Life has also become the first insurance company to collaborate with the newly opened Gleneagles MediCentre in Admiralty, further expanding its service scope through exclusive programmes. These programmes include gastroscopy, colonoscopy and wart removal services, providing customers with prevention-oriented health management solutions.New Territories: CUHK Medical CentreCUHKMC will serve as the selected medical network partner for the New Territories. Backed by a top-tier medical team comprising professors from the CUHK Faculty of Medicine and specialists, coupled with advanced medical facilities and strong research capabilities, CUHKMC provides customers with premium, multi-specialty medical services. Dedicated to translating cutting-edge international medical research into clinical practice, CUHKMC delivers a world-class diagnostic and treatment experience that benefits both customers and the wider community.Kowloon: Hong Kong Baptist HospitalHKBH will serve as the designated medical network partner for Kowloon. Operating under a “One Hospital, Multiple Service Sites” synergy model, the hospital enables patients to conveniently access medical services close to their preferred location. Among these sites, the HKBH East Kowloon Medical Centre (EKMC), located in the Kwun Tong Business District (Ngau Tau Kok), provides pre-approved direct billing services for cataract surgery and oncology treatments. Additionally, mental health team offers professional guidance to help individuals better understand and manage their psychological well-being. Together, these services embrace the Hospital mission: “In the Service of Man, for the Glory of God.”Customer-Exclusive Medical Services Reflects a People-Centric ApproachThrough this collaboration, the three hospitals will offer the following services for CTF Life customers:- Priority referral and appointment scheduling, significantly reducing waiting time.- Direct billing services, allowing customers to receive treatment without upfront payment, easing financial pressure.- One-stop cancer treatment services, covering diagnosis, treatment, and post-surgery rehabilitation, providing comprehensive support throughout the care journey.- Access to premium medical services and coordination, arranging professor-level doctors and advanced medical facilities to ensure customers receive the highest quality of medical care.Man Kit Ip, Executive Director and Chief Executive Officer of CTF Life (middle); Ellick Tsui, Executive Director, Deputy Chief Executive Officer and Chief Financial Officer of CTF Life (second from right); Dr Kenneth Tsang, Regional Chief Executive Officer of IHH Healthcare North Asia and Chief Executive Officer of Gleneagles Hospital Hong Kong (second from left); Dr Chung Kin Lai, Chief Executive Officer of CUHK Medical Centre (first from right); and Dr Leung Chi Bon, Chief Executive Officer of Hong Kong Baptist Hospital (first from left), announce the establishment of strategic partnerships at the kick-off ceremony.About CTF LifeChow Tai Fook Life Insurance Company Limited (“CTF Life”) is proud of its rich, 40-year legacy in Hong Kong. CTF Life is a wholly-owned subsidiary of CTF Services Limited (“CTFS”) (Hong Kong Stock Code: 659) and one of the most well-established life insurance companies in Hong Kong. As a member of Chow Tai Fook Enterprises Limited, CTF Life consistently strengthens its collaboration with the Chow Tai Fook Group ecosystem to support customers and their loved ones in navigating life’s journey with personalised planning solutions, lifelong protection and diverse lifestyle experiences. By leveraging the Group’s robust financial strength and strategic investments across the globe, CTF Life aspires to become a leading insurance company in Asia while continuously creating value beyond insurance.Media enquiriesCTF LifeCorporate Communications DepartmentVecinia Lau+852 2591 8297vecinia.lau@ctflife.com.hk Chow Tai Fook Life Insurance Company Limited (Incorporated in Bermuda with limited liability) Copyright 2025 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

- The 27th Hong Kong International Lighting Fair (Autumn Edition) opened today and will run for four days, and the 10th Hong Kong International Outdoor and Tech Light Expo will open tomorrow. The twin lighting fairs bring together some 3,000 exhibitors from 20 countries and regions.- The returning Innovative Lighting Design Forum held today features case studies and global market insights.- Renowned lighting designer Tino Kwan will host a masterclass tomorrow (28 October) at HKCEC titled “The Language of Light: From Artistic Design to Everyday Experience.”- Several exhibitors set up immersive experience zones, to enable visitors to explore product trends in human-centric lighting, artificial intelligence, and the silver market.HONG KONG, Oct 27, 2025 - (ACN Newswire via SeaPRwire.com) – The 27th Hong Kong International Lighting Fair (Autumn Edition), organised by the Hong Kong Trade Development Council (HKTDC), opened today and will run for four days until 30 October at the Hong Kong Convention and Exhibition Centre, while the 10th Hong Kong International Outdoor and Tech Light Expo will take place from 28 to 31 October at AsiaWorld-Expo.Deputy Executive Director of the HKTDC Jenny Koo said: "The development of innovative lighting products is thriving, with significant growth potential. Under the theme “Illuminated Designs for a Smarter Future”, the twin lighting fairs showcase innovative products and smart lighting solutions from some 3,000 exhibitors across 20 countries and regions. The fairs are highly international, in addition to exhibitors from Hong Kong, the Chinese Mainland and Taiwan, we also welcome exhibitors from Denmark, Finland, Germany, the Netherlands, the United Kingdom and the United States.”Centred on innovation and smart design, the Hall of Connected Lighting, which was upgraded last year, returns as the event’s focal point. The hall features some 70 leading brands, with an increase in the number of brands, countries and regions represented. In addition to showcasing a wide range of innovative smart lighting products and solutions, the hall also features several specially designed experience zones, showcasing meticulously designed scenarios, cutting-edge applications, and technologies. In the experience zone, visitors will be immersed in a multi-dimensional light installation that fuses art and technology, and experience a hands-on encounter with AI integrated applications in health and wellness, as well as innovative solutions for the silver market. The Hall of Connected Lighting features renowned brands such as Casambi from Finland, Moorgen from Germany, Signify from the Netherlands, and Koizumi from Japan, showcasing award-winning designs, designer collections, and lamps and lighting solutions used in iconic projects around the world. Major industry alliances playing key roles in the fields of smart lighting and the Internet of Things are gathered at the fair, including the DALI Alliance and SILA-EMN Alliance, as well as new participants this year such as the Connectivity Standards Alliance and the Zhaga Consortium, collectively presenting the full spectrum of the smart lighting ecosystem. They bring together member enterprises from around the world, including Elite Intelligence, Broadlink and Inventronics from the Chinese Mainland, LEDiL from Finland, France’s Nicolaudie, and Germany’s CUPOWER to showcase the smart lighting ecosystem.Another highlight is the Hall of Aurora, which brings together some 540 renowned brands offering high-quality lighting products. They include Prosperity Group and General Lighting from Hong Kong, LEEDARSON, Tospo and Je Woo from the Chinese Mainland, Lival from Finland and Megaman from Germany. Other featured zones include Commercial Lighting, LED Essentials, LED Lighting, Residential Lighting and Testing, Certification & Inspection, providing buyers with one-stop sourcing opportunities.The Hong Kong International Outdoor and Tech Light Expo showcases a diverse range of outdoor commercial and industrial lighting solutions, enabling the development of smart cities. The Smart Pole and Solution Zone, introduced last year, will return to showcase innovative solutions that aid in enhancing the quality of life and energy efficiency optimisation. E-Lite Semiconductor Inc. showcases its smart light poles, equipped with energy-efficient LED lighting and Environmental Sensing technology. These poles monitor air quality, temperature, humidity, and noise levels, and assist with real-time traffic monitoring when integrated with traffic cameras and sensors. Furthermore, Shenzhen Zhongchuang Lighting Technology presents its patented modular square stadium lights in the Technical & Professional Lighting zone. Engineered for functionality, the product allows for individual module replacement in the event of damage – greatly simplifying installation and maintenance while reducing operational costs. The Horticultural Lighting zone showcases advanced horticultural lighting technologies and multifunctional lamps suitable for outdoor parks and home gardens. The Outdoor and Public Lighting zone continues to showcase lamps designed for outdoor public spaces and advertising.Twin fairs focus on multiple lighting trendsImmersive smart lighting experience and design master series Smart homes are becoming increasingly popular. According to Statista, smart lighting is projected to become a massive $44 billion market by 2030, allowing users to adjust brightness, colour and temperature as needed. Exhibitors at this year's Autumn Lighting Fair have also thoughtfully designed various settings to offer buyers hands-on experiences. For example, Casambi has created the Artisan Café, a boutique coffee space illuminated in collaboration with ERCO, a globally acclaimed architectural and commercial lighting brand. Combining digital lighting systems with on-site ambiance, the café offers attendees a unique and immersive experience to connect and exchange ideas while enjoying their coffee. The lighting is configured to simulate natural light at different times of the day, featuring four distinct scenario demonstrations. TUYA Smart has constructed scenes such as living room and a bedroom to demonstrate how lighting and AI technologies can be integrated into smart lighting solutions. Moorgen also presents several cross-over collections from global design masters, including smart lamps designed in collaboration with two receivers of the DFA World’s Outstanding Chinese Designer Award, Chi-wing Lo and Tino Kwan; acclaimed Hong Kong architect, interior and product designer Steve Leung; Spanish designer Jorge Herrera; and internationally renowned design studio Yabu Pushelberg. Among the innovations on show, the Flower of Paris Motorised Track Light makes its global debut at the Autumn Lighting Fair and features a design collaboration with Ma Yansong – the first architect from the Chinese Mainland to win the right to design an international landmark building. As the result of two years’ development, the track light features a 355-degree rotating head and adjustable beam angles of 10, 15 and 25 degrees, flexibly illuminating every detail. Equipped with an intelligent control system, the track light can be operated remotely with effortless scene switches. Architectural lighting fixtures designed by Tino Kwan also makes a Hong Kong debut.Lighting and health are interdependent "Human-centric lighting" will continue to be a key focus in 2025. From lighting solutions that align with circadian rhythms to antibacterial UV-C technology, lighting is becoming a tool for enhancing health. Signify unveils its VitaUp Vitamin D3 Modules by Philips at the fair, offering a safe, controlled source of low-intensity UVB exposure to naturally support healthy vitamin D levels. Designed for long-term and low-intensity use, five-days of exposure delivers the equivalent UVB dose of a 15-minute midday walk two to three times per week in spring or summer. Another highlight is that Jiangsu Insona Communication Technology Co. also brings a smart lighting system that uses a circadian algorithm synchronised with local sunrise and sunset times without requiring network connectivity, thereby supporting the body’s natural biological rhythm. Foshan Electrical and Lighting Co. also sets up an experience zone to launch its Eye-care Ceiling Light, specially designed to meet the needs of the silver market. Tailored for elderly people, the light improves visual clarity by 15%, supports circadian rhythm and boosts lighting efficiency by 12%, reducing eye fatigue.Award-winning designs and global landmark lighting showcased at the twin fairs According to a lighting industry survey conducted by the HKTDC in April, 37% of respondents believe LED lighting has the greatest growth potential. A wide array of LED-innovations are on display, including the Filmbase flying screen developed by Filmbase Tech, a national-level high-tech and Specialised, Refined, Distinctive and Innovative enterprise. This ground-breaking product has set a new Guinness World Record as the world’s largest LED mesh mid-air suspended screen. Hong Kong’s GRE Alpha brings LED drivers and light strings that were used in the lighting show and horticultural system at Gardens by the Bay in Singapore. General Lighting Innovation showcases its Neon Strip which is renowned for its exceptional flexibility, impact resistance and all-weather durability. The latest models allow custom cutting and instant connection on site, enabling versatile installation to suit various spatial designs and creative lighting applications. At the Hong Kong International Outdoor and Tech Light Expo, AGC Lighting Co showcases several outdoor lighting fixtures that have won the German IF Design Award and the Red Dot Design Concept Award. Among them, the UFO High Bay Light features a unique design, enhanced by precision optics and high-efficiency power components. Its integrated system allows for both power and correlated colour temperature (CCT) adjustments in the one fixture.Experts discuss market trendsThe Innovative Lighting Design Forum held today (27 October) at the HKCEC explored two key themes: “City Design.Design City: Lighting Design Bound Up with Daily Life” and “RCEP Opportunities Shining Through Cultural Lighting Design”. Speakers included representatives from celebrated international and local companies, as well as architects and lighting designers, who shared top design cases from various regions and analysed market trends. Tomorrow (28 October), the Connected Lighting Forum will delve into smart living ecosystems and sustainable lighting development. It will also feature the launch ceremony for “Edge Mixed Networking (EMN) Technical Requirements for Smart Buildings”. On the same afternoon, renowned lighting designer Tino Kwan will host a masterclass titled “The Language of Light: From Artistic Design to Everyday Experience” and share design principles for enhancing daily life through light and the impact of light on mood, functionality and spatial characteristics. Additionally, a seminar titled “Illuminating the Cycle: Outdoor Lighting Designs for a Sustainable Future” will be held tomorrow (28 October) at AsiaWorld-Expo, focusing on how outdoor lighting can integrate sustainability concepts.Running concurrently from 28 to 31 October, the Outdoor and Tech Light Expo and Eco Expo Asia at AsiaWorld-Expo, alongside the Autumn Lighting Fair at the Hong Kong Convention and Exhibition Centre (HKCEC), present a dynamic platform for cross-sector business opportunities. Free shuttle bus services will be provided between the HKCEC and AsiaWorld-Expo from 28 to 30 October.Under the EXHIBITION+ hybrid model, exhibitors and buyers can meet online through the Click2Match business matching platform in addition to attending the physical fair. The online fairs run from 20 October to 7 November, facilitating business expansion both online and offline. 27th HKTDC Hong Kong International Lighting Fair (Autumn Edition)10th HKTDC Hong Kong International Outdoor and Tech Light ExpoDate27-30 Oct 2025 (Monday to Thursday)28-31 Oct 2025 (Tuesday to Friday)Opening hours27-29 Oct 2025: 9:30am-7pm30 Oct 2025: 9:30am-4pm28 Oct 2025: 10:30am-6pm29-30 Oct 2025: 10am-6pm31 Oct 2025: 10am-5pmVenueHong Kong Convention and Exhibition CentreAsiaWorld-ExpoPress Registration CounterHall 1C Concourse, HKCEC, or at the HKTDC Media Centre (G/F, HKCEC, 1 Expo Drive, Wan Chai)AsiaWorld-Expo East LobbyMedia CentreHKTDC Media CentreRoom 108, Hall 8 Side Entrance, AsiaWorld-ExpoFair websitehklightingfairae.hktdc.com/tchkotlexpo.hktdc.comPhoto download: http://bit.ly/43F182CThe 27th HKTDC Hong Kong International Lighting Fair (Autumn Edition) opens today, showcasing a wide variety of smart lighting products and solutions.The Hall of Connected Lighting returns, showcasing designs and smart technologies from prominent companies and brands.Under the theme ‘Illuminated Designs for a Smarter Future’, exhibitors at the twin lighting fairs present multiple experiential zones featuring meticulously designed lighting scenes, cutting-edge applications, and technologies, allowing visitors to immerse themselves in a multi-dimensional light and shadow experience at the intersection of art and technology.The Hall of Aurora brings together some 540 notable brands offering high-quality lighting products and technologies.The Innovative Lighting Design Forum took place today and explored two key themes: “City Design.Design City: Lighting Design Bound Up with Daily Life” and “RCEP Opportunities Shining Through Cultural Lighting Design”. Representatives from celebrated international and local companies, as well as architects and lighting designers, shared design works from various regions and analysed market trends.Media enquiriesPlease contact the HKTDC’s Communications & Public Affairs Department:Stanley SoTel: (852) 2584 4049Email: stanley.hp.so@hktdc.orgClayton LauwTel: (852) 2584 4472Email: clayton.y.lauw@hktdc.orgHKTDC Newsroom: http://mediaroom.hktdc.com/enAbout HKTDCThe Hong Kong Trade Development Council (HKTDC) is a statutory body established in 1966 to promote, assist and develop Hong Kong's trade. With over 50 offices globally, including 13 in the Chinese Mainland, the HKTDC promotes Hong Kong as a two-way global investment and business hub. The HKTDC organises international exhibitions, conferences and business missions to create business opportunities for companies, particularly small and medium-sized enterprises (SMEs), in the mainland and international markets. The HKTDC also provides up-to-date market insights and product information via research reports and digital news channels. For more information, please visit: www.hktdc.com/aboutus. Copyright 2025 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com