Author: acn

- 华堂宁(R)全年銷量超400萬盒，同比增長91%，銷售額達4.929億元，同比增長93%，公司全面自主商業化運營成效卓著。- 實現創紀錄盈利，稅前盈利達11.064億元；現金餘額穩健，截至年末達 10.923億元，為持續運營發展奠定堅實基礎。- 毛利率提升至56.9%，銷售開支占比從59.9%優化至33.6%，盈利能力顯著增強。- 华堂宁(R)原價續約新版醫保目錄，2026-2027年維持2025年的價格不變，臨床價值和創新價值再獲認可。- 隨著PTE獲批，中國市場獨佔權獲5年延期至2034年4月，商業確定性進一步提升。- 多格列艾汀（HYHOMSIS(R) ，華領片(R)）獲得香港地區上市批准，加速其面向東南亞的全球擴張進程。- 發佈多項真實世界證據，證實多格列艾汀治療優勢。- 持續拓展血糖穩態治療潛力，啟動多項全新的疾病首創新適應症研究，研究範圍涵蓋糖尿病預防、罕見病、輕度認知障礙及衰弱症領域。上海, 2026年3月27日 - (亞太商訊 via SeaPRwire.com) - 華領醫藥（「公司」，香港聯交所股份代號：2552）宣佈公司及其附屬公司截至2025年12月31日止年度（「報告期」）經審核的綜合業績。報告期內，公司核心產品、全球首創抗糖尿病新藥、葡萄糖激酶激活劑（GKA）华堂宁(R)（多格列艾汀片）實現全方位推進，公司自主商業化團隊於運營首年即實現高效組建和運轉，研發管線持續豐富，財務表現實現歷史性突破，成功邁入盈利新階段，為全球糖尿病治療領域的創新發展注入強勁動力。華領醫藥創始人、CEO陳力博士表示：「2025年是華領醫藥商業化運營中的意義非凡的一年。公司成功完成從研發驅動型組織向商業化驅動型組織的轉型，具備了全球首創新藥、血糖穩態調節劑华堂宁(R)的完全自主商業化運營能力。憑藉強勁的市場執行力與產品競爭力，相較於2024年將商業化業務委託給營銷合作夥伴的階段，公司的銷量與營收實現了近三位數的增長。與此同時，通過推動多格列艾汀在香港的註冊工作，公司在全球市場拓展方面取得了關鍵性進展，我們將向覆蓋7億人口的東南亞地區進行市場佈局。我們持續拓展血糖穩態調控技術的臨床應用場景，積極佈局早期阿爾茨海默病、衰弱症等新適應症領域。針對GCK-MODY及衰弱症開展的疾病首創新藥研發工作，將為華領醫藥未來五年的創新發展劃定全新方向。」業務亮點與運營進展- 商業化全面發力，盈利實現歷史性突破2025年1月1日起，公司正式全面接管华堂宁(R)在中國的商業化工作，獲得全部運營與戰略主導權，公司成功搭建了專業的銷售團隊，覆蓋全國10個銷售區域，專注於產品營銷、醫學事務及商業運營。通過人工智能賦能的數字商業化平台，運營效率與銷售生產力大幅提升，為公司商業化發展注入新活力。受益於國家醫保藥品目錄的持續廣泛覆蓋，华堂宁(R)在二級和三級醫院的處方量顯著增長，患者可及性不斷提高，通過3000多家醫院、社區衛生中心、藥房和線上渠道，惠及超過50萬名患者。報告期內，產品銷量達401.1萬盒，同比增長91%；銷售額達4.929 億元，同比增長93%，在單價保持穩定的情況下，充分印證了市場需求的強勁增長和自主商業化團隊的高效執行能力。盈利能力方面，2025年，公司毛利達到2.804億元，同比增長125%，得益於生產規模擴大及製造工藝優化，公司毛利率從2024年的48.7% 提升至56.9%，增加8.2個百分點；銷售開支僅增長1230萬元至1.655億元，占收入比例優化至33.6%，較2024年的59.9%大幅下降；商業化業務實現約1.149億元盈利（按毛利扣除銷售開支計算）。公司預期仍將持續擴充商業化團隊規模，但商業化運營的盈利趨勢也將持續增長。在2024年底終止與拜耳合作後，多格列艾汀銷售額創歷史新高，報告期內，公司稅前盈利增加至人民幣11.064億。截至2025年末，現金結餘約為人民幣10.923億元，穩健的現金情況為公司持續發展奠定了堅實基礎。- 全球佈局加速推進，核心權益得到強化公司全球化佈局邁出關鍵步伐。2026年2月27日，多格列艾汀（香港地區商品名：MYHOMSIS(R)，華領片(R)）成功獲得香港監管機構的上市批准，公司計劃2026年中正式在香港市場推出該產品，並將進一步向亞洲地區拓展。此外，公司已于2025年向澳門藥監局遞交華領片(R)（MYHOMSIS(R)）的新藥上市申請。公司在知識產權保護方面也再獲進展。2026年2月，中國國家知識產權局批准多格列艾汀專利期限補償（PTE）申請，核心專利保護期延長至2034年4月，新增5年市場獨佔權，為產品長期市場競爭提供有力保障。2025年，多格列艾汀獲中國監管機構認定為國家級創新藥及慢病有效治療藥物，國家醫保局已確認，2026-2027年，华堂宁(R)的國家醫保目錄價格維持不變，公司將持續保障產品的市場競爭力和患者可及性，尤其在二級和三級醫院，加速患者的用藥普及。- 真實世界研究推進，臨床價值獲持續驗證真實世界證據（RWE）研究持續佐證多格列艾汀在葡萄糖依賴性胰島分泌功能改善中的關鍵作用，並顯示其在糖尿病預防、緩解及延緩或預防糖尿病併發症方面的功效。HMM0701已完成入組，共招募380名2型糖尿病患者。2025年6月，在美國ADA年會上發表的中期分析結果顯示，86%的患者同時服用兩種或以上降血糖藥物，41%的患者使用胰島素。經6個月治療後，血糖控制明顯改善，糖化血紅蛋白由8.1%降至7.3%，平均TIR（目標範圍內時間）提升至70%以上。迄今為止的研究顯示，多格列艾汀與其他降糖藥物聯合使用時，患者的餐後血糖水平和β細胞功能均顯著改善。另外，在美國進行的多格列艾汀機制研究（採用雙示蹤劑測量法），為平均確診糖尿病17年的2型糖尿病患者的肝糖原生成提供了科學證據。在該研究中，患者每日服用兩次多格列艾汀，持續6周。結果顯示，多格列艾汀能增加葡萄糖直接流入肝糖原的通量，意味著其有助於恢復肝臟GK功能。結合臨床研究數據顯示，多格列艾汀可改善早期胰島素釋放和GLP-1分泌，恢復2型糖尿病患者的肝臟GK功能，不僅為控制餐後血糖波動提供重要途徑，並在控制糖尿病併發症（如糖尿病腎病變及輕度認知障礙）方面提供獨特契機。HMM0601研究已經完成臨床試驗，共納入2000名受試者，平均患病時間為7.9年，其中超過30%患病時間超過10年。初步結果顯示，多格列艾汀在中國2型糖尿病患者中安全性、耐受性良好。研究中未觀察到新的不良反應，不良反應發生率維持在III期臨床試驗中觀察到的低水平，患者的用藥依從性普遍較高，平均依從率約為95%。在本研究中，80%的受試者已使用一種或多種口服降血糖藥，20%的受試者使用胰島素。多格列艾汀不僅在整體患者群體中展現出良好的療效及安全性，在老年、肥胖及高血糖患者群體中同樣有效，無論作為單藥治療或與二甲雙胍、SGLT-2抑制劑、胰島素及其他藥物聯合使用。頂線結果將於2026年ADA年會上發表。- 臨床研發持續深化，新適應症不斷拓展多格列艾汀用於治療MODY-2患者。中國內地及香港地區醫學專家已獨立開展多格列艾汀用於MODY-2治療的臨床研究及臨床前研究。MODY-2（又稱GCK-MODY）是一種單基因疾病，患者因葡萄糖激酶基因(GCK)存在遺傳缺陷，導致血糖升高及第二時相胰島素釋放顯著減少。在中國，MODY-2患者群體規模約為170萬人。此類患者確診糖尿病時年齡偏小，且由於現有治療藥物療效不佳，這一患者群體存在未被滿足的醫療需求。中國研究人員在針對MODY-2患者的臨床研究中報告指出，對於先前使用二甲雙胍、TZD、DPP-4抑制劑及SGLT-2抑制劑仍無法控制高血糖的MODY-2患者，多格列艾汀能有效將血糖降至正常水平。其他結果顯示，單劑量多格列艾汀可顯著改善這類患者的整體葡萄糖敏感性及第二時相胰島素分泌，表明多格列艾汀具有調節GLP-1分泌的獨特作用機制。基於以上結果，華領醫藥已與國家藥品監督管理局（NMPA）藥品審評中心溝通，將於2026年提交多格列艾汀用於MODY-2患者的IND申請。多格列艾汀用於糖尿病預防。糖尿病預防是華領醫藥的重要研發重點。公司已於香港啟動針對糖尿病前期糖耐量異常（IGT）受試者及早期糖尿病患者的SENSITIZE 3臨床研究。這項雙盲安慰劑對照研究將評估受試者在靜脈葡萄糖耐量試驗及口服葡萄糖耐量試驗下的血糖控制及胰島功能，以更明確界定臨床治療基線及終點指標。我們預計於2026年完成研究後，將在中國及亞太地區探索提交多格列艾汀用於糖尿病預防的IND申請的新機遇。多格列艾汀用於神經退行性疾病。研究顯示，中國老年人的輕度認知障礙患病率約為15.5%，美國則約為22%；該症狀在2型糖尿病患者中也相當常見，發病率達45%。多格列艾汀用於神經退行性疾病的研究已成為公司藥物研發工作的新焦點。通過全基因組關聯分析(GWAS)及孟德爾隨機化（MR）研究，我們發現GK基因激活在預防人類記憶力衰退及認知障礙方面具有重要作用。同時我們也發現，餐後血糖波動與阿茲海默症及失智症密切相關。血糖穩態異常及糖尿病狀況會導致大腦葡萄糖轉運蛋白及胰島素受體表達減少，而低劑量多格列艾汀可預防該功能損傷。我們已確認多格列艾汀在治療輕度認知障礙方面的潛在價值，並將於未來啟動針對該疾病領域的首創療法的相關臨床研究。多格列艾汀用於治療衰弱症。衰弱症是一種與年齡相關的老年綜合症，其特徵為對內外應激因子的耐受性降低。約17%的美國人及11%的亞洲人（50歲以上）患有衰弱症，而處於衰弱症前期者則分別約占此兩個群組的50%及47%。衰弱症並非單一器官疾病，而是多系統內穩態失調所導致的後果。遺傳學證據支持GK激活對降低衰弱症風險具有因果作用。我們計劃於未來啟動臨床研究，以推進多格列艾汀在衰弱症治療領域的應用。聯合用藥用於糖尿病及併發症的治療。臨床與基礎研究結果顯示，多格列艾汀能恢復胰腺在葡萄糖刺激下的胰島素及GLP-1分泌，也可以通過恢復2型糖尿病患者肝臟葡萄糖激酶功能，改善肝臟胰島素敏感性並降低肝臟胰島素抵抗。多格列艾汀與DPP-4抑制劑、SGLT-2抑制劑及GLP-1受體激動劑的聯合使用已證明可有效調節脂質代謝，與抗癌PI3K抑制劑聯合使用的研究也為血糖穩態管理帶來獨特優勢。- 產品管線豐富多元，創新佈局未來增長華領醫藥在核心產品基礎上持續豐富管線佈局。依託多格列艾汀與二甲雙胍聯合用藥在III期臨床試驗和真實世界應用中取得的優異數據，公司加速推進多格列艾汀與二甲雙胍固定複方製劑（FDC）的研發。該製劑為每日兩次給藥方案，適用于單用二甲雙胍血糖控制不佳的2型糖尿病患者，旨在以進一步提升患者的用藥依從性。公司已向NMPA提交IND申請文件。此外，GMP商業化生產工藝也已成功開展，為2027年新藥上市申請的關鍵生物等效性研究做好準備。臨床研究顯示，多格列艾汀與二甲雙胍聯用能夠更好地控制血糖，降低餐後血糖，改善空腹血糖，為優化血糖穩態終點提供了新的臨床價值。第二代GKA的研發取得重要突破。作為肥胖2型糖尿病患者每日一次治療的緩釋新片劑，公司已在美國啟動多格列艾汀多劑量遞增（MAD）研究，以探討第二代GKA在血糖穩態控制方面的療效及新藥的作用機制，首例患者已於2025年12月入組，預計2026年中公佈頂線數據。同時，公司還在探索多格列艾汀與GLP-1受體激動劑、SGLT-2抑制劑等藥物的聯合治療方案。近期，在一項中國的臨床試驗中，研究者報告：多格列艾汀聯合司美格魯肽治療12周，療效顯著優於司美格魯肽單藥治療。聯合治療組在血糖控制、體重相關指標及β細胞功能等多項關鍵指標上均表現更優。財務摘要截至2025年12月31日，- 华堂宁(R)全年銷量約401.1萬盒，相較2024年全年，同比增長91%，實現營收約4.929億元，同比增長93%。- 毛利約人民幣2.804億元，同比增長125%，毛利率提升至56.9%；- 稅前盈利約人民幣11.064億元，較2024年增長542%；- 銀行結餘及現金約人民幣10.923億元，資金狀況穩健；- 總開支約人民幣4.334億。前瞻性聲明本文包含有關華領醫藥以及產品未來預期、計劃和前景的陳述。該等前瞻性陳述僅與本文作出該陳述當日的事件或資料有關，可能因未來發展而出現變動。除法律規定外，於作出前瞻性陳述當日之後，無論是否出現新資料、未來事件或其他情況，我們並無責任更新或公開修改任何前瞻性陳述及預料之外的事件。請仔細閱讀本文並理解，由於各種風險、不確定性或其他法定要求我們的實際未來業績或表現可能與預期有重大差異。關於華領華領醫藥（「本公司」）是一家總部位於中國上海的創新藥物研發和商業化公司，在美國、中國香港設立了公司。華領醫藥專注於未被滿足的醫療需求，為全球患者開發全新療法。華領醫藥彙聚全球醫藥行業高素質人才，融合全球創新技術，依託全球優勢資源，研究開發突破性的技術和產品，引領全球糖尿病醫療創新。公司核心產品华堂宁(R)（多格列艾汀片）以葡萄糖傳感器葡萄糖激酶為靶點，提升2型糖尿病患者的葡萄糖敏感性，改善患者血糖穩態失調。2022年9月30日，华堂宁(R)已獲得中國國家藥品監督管理局（NMPA）的上市批准，用於單獨用藥或者與二甲雙胍聯合用藥，治療成人2型糖尿病。對於腎功能不全患者，無需調整劑量，是一款可用於腎功能損傷的2型糖尿病患者的口服降糖藥物。2026年2月，多格列艾汀（商品名：MYHOMSIS(R)，華領片(R)）獲得中國香港特別行政區政府衛生署藥物辦公室的上市批准。詳情垂詢華領醫藥網址：www.huamedicine.com投資者電郵：ir@huamedicine.com媒體電郵：pr@huamedicine.com新聞免責聲明本材料，如為上下文論述的準確性和完整性，提及在中國上市的產品相關信息的，特別是標識或要求，應遵循中國監管機構批准的相關文件。另外，相關信息不應被解讀為對任何藥物或者診療方案的推薦或者宣傳，亦不應替代任何醫療衛生專業人士的醫療建議，涉及醫療的相關事宜務必諮詢醫療衛生專業人士。 Copyright 2026 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com

HONG KONG, Mar 27, 2026 - (ACN Newswire via SeaPRwire.com) – 26 March, Unisound (09678.HK) announced its audited annual results for the year ended December 31, 2025. As the Company's first annual results announcement since listing, it underscores strong growth momentum and continued improvement in its financial profile.Revenue Mix Continues to Improve, with Faster Growth in H2For the full year of 2025, Unisound achieved total revenue of $175 million, representing a year-on-year (YoY) increase of 29%. Revenue in the second half of the year increased by 33% YoY to $117 million.It is worth noting that the Company's large language model (LLM) business generated a full-year revenue of $88.43 million, surging by over 10 times YoY. In particular, this business contributed approximately $72.49 million in H2 revenue, five times the level recorded in H1, demonstrating a compelling capacity for large-scale commercial application.Losses Narrowed Significantly, Making the Path to Profitability Increasingly ClearAlongside the rapid revenue growth, the Company's losses improved markedly. In the second half of 2025, the Company's net loss narrowed by 84% YoY, and its adjusted loss narrowed by 92% YoY, approaching break-even. This reflects the Company's ongoing improvements in cost control and operational efficiency.Simultaneously, some of the Company's operating metrics saw marked improvement. The adjusted expense ratio declined significantly by 10 percentage points YoY, while selling expenses decreased rather than increased and accounted for only 5.4%, highlighting a clear improvement in cost-to-efficiency ratio. In 2025, revenue per employee reached $365,300, up 25% YoY from $292,900 in 2024. Employee productivity continued to lead the industry, clearly underscoring the Company's core strengths in technology-driven, lean operations.Dual-Engine Strategy Gains Traction, with AI in Healthcare and AI in Daily Life Advancing in TandemIn 2025, driven by both technological breakthroughs and policy tailwinds, global demand for AI continued to rise. Unisound adhered to its "Strong Foundation Model + Deep Application" strategy, continued to strengthen its multimodal technology foundation, and drove the continuous elevation of the global influence of its proprietary large model matrix in fields such as healthcare, speech, and OCR.On the commercialization front, the Company leveraged its AI-native organization to accelerate business execution, and its dual-engine strategy in AI in Healthcare and AI in Daily Life delivered notable results. During the reporting period:The AI in Daily Life business achieved revenue of $140 million, a YoY increase of 30.8%. Among this, the Transportation segment recorded nearly 40% YoY growth. At present, AI agent applications based on the Shanhai large model have been deployed in more than 10 cities, including Qingdao, Ningbo, Shenzhen and Nanning. In addition, cumulative AI chip shipments exceeded 110 million units, further validating the Company's scale capabilities in endpoint AI products.The AI in Healthcare business achieved revenue of $35.38 million, a YoY increase of 22.3%, with average revenue per customer growing by 53.2% YoY. In 2025, over 70% of the hospitals the Company collaborated with were tertiary hospitals, and more than one-third of customers had maintained continuous cooperation for over three years. The medical-record entry and generation products powered by the medical large model delivered a 10-fold YoY increase in full-annual medical record generation at a single campus of a leading Class III hospital. The commercial insurance AI agent platform recorded a 37-fold YoY increase in case processing volume. In deep cooperation with a leading insurance group, the expense control rate was effectively raised to approximately 20%, delivering more than $145 million in incremental cost management compared with traditional review methods, comprehensively empowering insurance institutions to refine their medical risk management operations.Continued R&D Investment Strengthens the Technology MoatTo consolidate its industry-leading position, the Company continued to invest heavily in R&D in 2025. Full-year R&D expenses exceeded $55.09 million, accounting for 75% of the Company's adjusted operating expenses, while R&D personnel accounted for 69% of the total workforce. This sustained investment drove breakthroughs across multiple technology areas. For example, in the MedBench 4.0 evaluation, the Company ranked first place in three technical paradigms: "Medical AI Agent," "Medical Large Language Model," and "Medical Multimodal Large Model," earning a "Triple Crown."Outlook: Deepening the Technological Foundation and Expanding Application BoundariesLooking ahead, Unisound will continue to deepen its "Strong Foundation Model + Deep Application" strategy. On the technological front, the Company will continue to increase strategic investment in foundational large models and strive to maintain a world-class level. On the application front, it will use the large-scale expansion of MaaS (Model-as-a-Service) and AI agents as its core growth engine, driving exponential growth in its AI in Daily Life and AI in Healthcare businesses. Meanwhile, the Company is actively exploring the establishment of a recurring revenue system through models such as API calls and Token-based billing, and regards opportunities in consumer-facing (C-end) products as a second growth curve to further expand its commercialization boundaries.Between Q2 and Q3 2026, Unisound will launch a native AI agent large model for programming and office applications, which is expected to double both intelligence density and token production efficiency. Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

香港, 2026年3月27日 - (亞太商訊 via SeaPRwire.com) - 3月26日，雲知聲（09678.HK）發佈截至2025年12月31日止年度的經審核全年業績，展現上市後首份成績單強勁的增長動能與持續優化的財務結構。營收結構持續優化，下半年增長提速2025年全年，雲知聲實現總營收12.1億元人民幣，同比增長29%。其中，下半年收入同比增長33%，達8.1億元。值得關注的是，公司大模型業務全年收入6.1億元，同比增長超10倍。尤其是下半年，該業務貢獻收入約5億元，為上半年規模的5倍，顯示出強勁的規模化落地能力。虧損大幅收窄，盈利路徑日漸清晰在營收高速增長的同時，公司虧損狀況顯著改善。2025年下半年，公司淨虧損同比收窄84%，經調整後虧損同比收窄92%，接近盈虧平衡點，反映出公司在成本控制與運營效率方面的持續優化。同時，公司的部分經營指標也得到明顯改善。經調整營業費用率較去年同比大幅下降10%，銷售費用不升反降，佔收入比重僅為5.4%，費效比提升明顯。從數據端來看，2025年公司人均產值為252萬元/人，相較24年的202萬元同比增長25%，人均創效能力持續領跑行業，直觀彰顯了公司技術驅動、精益運營的核心優勢。雙輪驅動戰略落地，智慧醫療與智慧生活齊頭並進2025年，在技術突破與政策紅利的雙重驅動下，全球人工智能市場需求持續升溫。雲知聲堅持「強基模+深應用」戰略，持續夯實全模态技術底座，推動自研大模型矩陣在醫療、語音、OCR等領域的全球影響力不斷提升。在商業化層面，公司以AI原生組織推動業務落地，智慧醫療與智慧生活雙輪驅動戰略成效顯著。報告期內：智慧生活業務實現收入9.68億元，同比增長30.8%。其中，智慧交通業務同比增長近40%，目前，已在青島、寧波、深圳、南寧等10餘個城市落地基於山海大模型的智能體應用。此外，AI芯片累計出貨量突破1.1億顆，進一步驗證公司在終端AI產品的規模化能力。智慧醫療業務實現收入2.44億元，同比增長22.3%，客單價同比增長53.2%。2025年，合作的醫院中超70%為三級醫院，且超過三分之一客戶已經連續合作三年以上；而基於醫療大模型的病歷錄入與生成產品已在某頭部三甲醫院單院區實現全年病歷生成同比增長10倍；商業保險智能體平台案件處理量同比增長37倍；與頭部保險集團的深度合作中，控費率水平有效提升至約20%，相較傳統審核方式實現超10億元級別的增量成本管控，全面賦能保險機構在醫療風控領域的精細化運營。持續加碼研發，夯實技術護城河為鞏固行業領先地位，2025年公司持續在技術端大力投入，全年研發費用超3.8億元，佔經調整三費的75%；研發人員佔比達69%。持續的研發投入在多個技術領域取得突破，如在MedBench 4.0評測中，公司一舉斬獲「醫療智能體」「醫療大語言模型」「醫療多模态大模型」三項技術範式第一，榮膺「三冠王」。未來展望：深耕技術底座，拓展應用邊界展望未來，雲知聲將繼續深化「強基模+深應用」戰略。技術層面，公司將持續加大對基座大模型的戰略性投入，力爭保持全球一流水平；應用層面，將以MaaS（模型即服務）與智能體的規模化拓展為核心增長引擎，推動智慧生活與智慧醫療業務的指數級增長。同時，公司正積極探索以API調用、Token計費等模式構建經常性收入體系，並將C端產品機會作為第二增長曲線，進一步拓展商業化邊界。2026年第二季度，雲知聲將推出面向編程和辦公的原生智能體大模型，並預計能實現智能密度和Token生產效率的倍增。 Copyright 2026 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com

香港, 2026年3月27日 - (亞太商訊 via SeaPRwire.com) - 2026年3月26日，心瑋醫療（06609.HK）公佈了2025年業績公告。2025度，公司收入4.08億元，同比增長46.9%，淨利潤8334萬元，較上年度虧損約1362萬元實現重大扭虧為盈。這一轉變主要由於公司在缺血性卒中、出血性卒中及介入通路三大業務板塊均實現了收入的快速增長，同時公司的經營效率進一步提升。2025年，公司的缺血性卒中業務收入同比增長31.8%，主要由於：(1)公司具有差異化競爭優勢的顱內血栓抽吸導管得到臨床的廣泛認可，大腔抽吸及級聯抽吸技術(CATCH)被納入《急性缺血性卒中血管內治療技術中國專家共識2025》，產品進入超過450家醫院使用，收入規模快速提升；(2)成熟產品在納入集采後，銷量快速增長。在出血性腦卒業務中，公司已構建完整動脈瘤治療解決方案。公司的顱內支架（獲NMPA創新醫療器械認定）在首個商業化年度累計進入約500家醫院使用，帶動栓塞彈簧圈的市場份額快速提升。同時，公司的血流導向裝置於2025年獲NMPA批准上市，實現臨床推廣和應用。基於前述原因，公司的出血性卒中業務收入在2025年同比增長223.2%。在介入通路業務中，公司的明星產品血管封堵器累計進入超過1800家醫院使用，年終端醫院臨床使用量超過20萬條，在2025年實現單產品收入過億。與此同時，公司正推動第二代血管封堵器的開發和商業化，以繼續擴大市場份額。公司的毛利率從2024年度的65.4%提升至2025年的70.9%，主要由於高毛利創新產品的收入占比提升，以及公司持續推動的生產工藝改進、供應鏈優化等降本措施的有效實施。不斷完善的產品佈局以及持續的降本增效工作，使公司在面臨激烈的市場競爭情況下，仍能保持優質的產品品質及突出盈利能力。公司在業務規模擴大的同時，費用控制效果顯著，銷售及管理費用率較2024年相比從49.6%降至45.8%。報告期內，公司發生研發費用人民幣4076萬元，主要用於神經介入醫療器械及腦機介面等創新產品的開發。截至目前，公司已取得以下各項進展：(1)在缺血性卒中領域，公司已取得顱內血栓抽吸導管、取栓支架及配套通路產品的註冊證。公司的自膨式顱內藥物洗脫支架已完成對照臨床試驗，註冊申請已獲NMPA受理。根據公開信息查詢結果，目前全球未有類似產品獲批上市，公司在此類產品的研發進度上領先業界。在頸動脈狹窄領域，公司正推動開展頸動脈支架的臨床試驗工作；(2)在出血性卒中領域，公司是獲證最全面的國產公司，實現顱內支架（獲NMPA創新醫療器械認定）、血流導向裝置、栓塞彈簧圈、神經血管封堵球囊導管的完整佈局；(3)同時，公司正積極推進創新產品介入式腦機接口的研發工作。該產品在有效提取大腦信號以用於完成人機交互的同時，保障了手術的安全性和產品長期植入的穩定性，有望在2026年開展首例人體臨床試驗。2025年，公司的海外市場收入較2024年增長101.3%，這主要歸功於公司快速推進的海外產品註冊工作及產品推廣工作。海外市場方面，公司的取栓支架、封堵球囊導管、遠端通路導管以及微導管已取得CE或FDA認證，並在其他13個國家或地區取得56項註冊證書。截至目前，公司還在其他29個國家或地區開展超過130個產品註冊工作，擴展銷售管道，為實現海外銷售的長期目標建立基礎。2025年，公司經營性現金流1.55億元，帳面現金及存款7.86億元，整體資金狀況穩健。依託扎實的財務實力，公司已於2025年完成股份回購3936萬港元，並將持續推進股份回購工作，積極維護全體股東利益。此外，公司計劃於2026年提交A股科創板上市申請，借助登陸境內資本市場進一步提升股東回報水平與股份市場流動性。 Copyright 2026 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com

香港, 2026年3月27日 - (亞太商訊 via SeaPRwire.com) - 2026年3月26日，北京城建設計發展集團股份有限公司（"本公司"或"公司"，簡稱"城建設計"，股票代碼：1599.HK）董事會（"董事會"）欣然公佈本公司及其子公司（合稱"本集團"）截至2025年12月31日止年度（"2025年度"或"報告期"）的經審計業績。2025年，公司面對市場持續下行壓力，緊緊圍繞高質量發展，迎難而上、實幹擔當，聚焦主責主業，推動全產業鏈協同發力，階段性完成了"十四五"規劃主要目標任務，為新征程加快發展積蓄了強勁動能。截至2025年12月31日止年度，本集團實現收入為人民幣75.27億元。本集團實現淨利潤為人民幣5.36億元，同比上漲1.52%。綜合毛利率19.85%，同比上漲1.77%。核心主業與新興領域協同發力，高端諮詢品牌效應顯現設計、勘察及諮詢板塊為本集團的傳統和主營核心業務，報告期內，本集團軌道交通領域中標成都27號線二期、廈漳泉城際鐵路（廈門段）等重點項目；既有線改造市場成效顯著，中標北京、南京、哈爾濱、長春、瀋陽等一批代表性項目，市場份額保持領先；高端諮詢品牌效應持續顯現，成功承擔了香港鐵路標準、北京三期線網技術標準等標杆項目，專業服務能力穩步提升；境外業務紮實推進，在香港、新加坡、安哥拉、哈薩克斯坦、哥倫比亞持續獲取訂 單，新簽合同額突破人民幣1億元；民建、市政設計走特色化發展之路，在居住建築、大型TOD、校園、道路等傳統領域精耕細作，積極向展陳、城市更新、水環境治理領域延伸佈局。截至2025年12月31日止年度，本集團設計、勘察及諮詢板塊業務收入人民幣40.89億元。其中城市軌道交通工程板塊收入人民幣29.38億元，工業與民用建築和市政工程板塊收入人民幣11.51億元。本集團工程承包業務板塊專注於服務城市軌道交通建設項目和相關基礎設施建設項目，2025年，本集團中標北京軌道交通R4線一期北段01標、03標、M101線05標、市郊鐵路東北環線03標等項目，進一步鞏固了北京核心市場，在手工程承包項目主要集中在北京、廣州、重慶、烏魯木齊及青島等城市。截至2025年12月31日止年度，本集團工程承包業務板塊實現收入人民幣34.38億元。新建項目與存量改造雙線發力，中標額突破81億元，在手訂單儲備充足2025年，軌道交通行業面臨市場持續下行、招標規模顯著縮減、行業競爭加劇及宏觀經濟形勢不確定性增強的局面，公司始終全力以赴力爭中標軌道交通新建項目，尤其注重穩固北京區域市場份額。在守住基本盤的同時，積極佈局既有線改造、城市更新、能源、數字化及智慧等其他高潛力板塊，以應對市場變化並提升抗風險能力。截至2025年12月31日，公司中標金額人民幣81.71億元，其中設計、勘察及諮詢業務板塊中標人民幣26.39億元，工程總承包板塊中標人民幣55.32億元。報告期末公司在手合同額為人民幣251.43億元。2026年展望：錨定"十五五"開局，推動高質量發展2026年是"十五五"開局之年，面對深刻變化的市場形勢和艱巨繁重的發展任務，我們要積極把握戰略機遇，主動適應行業發展新格局，以穩中求進為總基調，以推動高質量發展為主題，以改革創新為根本動力，錨定打造"以設計為引領的城市建設綜合服務商"戰略目標，確保"十五五"開好局、起好步。有關城建設計北京城建設計發展集團股份有限公司（股份代碼：1599.HK）是國內第一家以城市軌道交通設計諮詢為引領的H股上市企業。公司前身是北京城建設計研究總院成立於1958年，是為中國首條地鐵北京地鐵1號線的勘察設計而成立。擁有國內設計勘察行業最高資質—綜合甲級資質。作為行業龍頭和市場規範的制定者，公司由成立至今仍保持市場佔有率第一的位置。基本業務涵蓋投融資、勘察設計諮詢、工程總承包、科技產業化、運營管理的城市軌道交通全產業鏈。公司市場覆蓋了全國已批復軌道交通建設規劃城市的80%，業務拓展到了國內近70個城市，在50多個城市擁有分支機構。新聞垂詢：千里國際顧問有限公司fancywang@maxima.hk Copyright 2026 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com

財務摘要人民幣（億元）截至12月31日止12個月變動2025年2024年營業收入1566.111,776.64-11.85%營業利潤28.4265.53-56.64%稅前利潤28.1665.95-57.30%毛利194.95222.47-12.37%毛利率12.45%12.52%-0.07pct淨利潤13.3741.95-68.12%歸屬于母公司股東及其他權益持有者的淨利潤2.2129.72-92.57%經營活動產生的現金流量淨額185.1492.6499.86%每股派息（元/股，含稅）0.1790.176N/A派發現金紅利（含稅）9.399.45-0.60%業績亮點1.經營底盤穩健，高品質發展韌性凸顯：2025年集團實現營業收入人民幣1566.11億元，淨利潤人民幣13.37億元，毛利率維持12.45%，海內外營收結構均衡。2.現金流與財務品質雙改善，抗風險能力顯著增強：經營活動現金流淨額大幅增長99.86%至185.14億元，期末貨幣資金餘額243億元；有息債務規模同比縮減47億元至人民幣344億元、淨利息費用同比下降約7.3億元，財務結構持續優化。3.現金分紅+回購雙管齊下，全力回報投資者：2025年擬每股派現金人民幣0.179元(含稅)，疊加年內推出的H股、A股多輪回購計畫，2025年度公司擬分紅及已回購金額合計達到人民幣18.52億元。4.能源相關業務盈利能力大幅躍升，成為集團重要增長極：海洋工程分部、金融資產管理分部(主要為鑽井租賃)淨利潤合計增長約12.12億，能源化工及液態食品分部增長3.08億。其中，海洋工程分部毛利率大幅提升5.72個百分點至14.83%。海洋工程、能源化工及液態食品在手訂單分別達50.9億美金及297.5億人民幣，部分船廠排產至2030年。5.物流相關業務穩固集團"壓艙石"作用：期內，集裝箱、道路運輸車輛等業務受匯率及週期波動影響，毛利率及盈利有所承壓，但基本盤穩健，行業競爭優勢持續鞏固，集裝箱標準幹箱、冷藏箱、化工罐箱、半掛車等核心產品連續多年保持全球第一。6.關鍵業務取得技術與訂單雙突破，競爭力獲高度認可：高端海工裝備領域，中集來福士攻克海工行業最複雜產品FPSO/FLNG，成為中國唯一一家擁有雙專案EPCI總包能力的企業；模組化資料中心領域，同時為超過300MW的行業客戶提供預製化資料中心的技術與製造交付服務，引領算力基礎設施新變革。香港, 2026年3月26日 - (亞太商訊 via SeaPRwire.com) - 中國國際海運集裝箱（集團）股份有限公司（簡稱"中集集團"或"集團"，股份代號：000039.SZ/02039.HK）欣然公佈截至2025年12月31日止12個月（"期內"）之經審核全年業績。中集集團管理層表示，2025年，全球百年變局加速演進，世界經濟在波折中展現韌性。置身于機遇與挑戰並存的時代洪流，集團緊緊圍繞"構建增長新動能、聚力高品質發展"主基調，不僅穩住經營基本盤，更以前瞻性戰略深化能源業務佈局，取得豐碩成果。2025年全年，集團實現營業收入人民幣1566.1億元，淨利潤達人民幣13.4億，公司經營活動產生的現金流量淨額大幅增長99.9%至185.1億元，資產結構持續優化，抗風險能力持續增強。特別地，為真情回饋廣大投資者，中集集團2025年擬向全體股東每1股份派現金股利人民幣0.179元（含稅），此次合計擬派發現金紅利人民幣9.39億元（含稅）；同時，中集集團於2025年度已實施的股份回購金額累計達9.13億人民幣，兩者合計總額達到18.52億元。主要板塊經營表現（人民幣億元）2025各項指標營業收入占總營收比重毛利占總毛利比重毛利率淨利潤集裝箱製造430.0927.46%57.5529.52%13.38%18.82道路運輸車輛201.7812.88%32.0616.45%15.89%9.27能源、化工液態食品裝備271.9217.36%40.2420.64%14.80%10.40海洋工程179.3811.45%26.6013.65%14.83%10.57物流服務 267.9317.11%16.708.57%6.23%3.64空港與物流裝備、消防與救援設備76.194.86%15.147.76%19.87%2.64以上主要板塊1427.2991.12%188.2996.59%13.19%55.34核心業務表現一、在物流領域集裝箱製造方面: 期內，雖受美國關稅政策擾動與地緣政治衝突等供應鏈負面因素影響，全球商品貿易仍展現出較強韌性，區域內貿易、亞歐及新興市場航線成為增量主力。與此同時，紅海繞行、港口擁堵、航運環保要求及貿易路徑複雜化等因素，降低了集運效率，從底層推升實際需求，全球集裝箱保有量進入新的結構性階段。綜上，2025年集裝箱新箱整體需求仍保持較好水準，高於過去十年均值。報告期內，集團集裝箱製造業務產銷量同比有所回落，符合行業整體預期，但仍舊保持全球第一。其中乾貨集裝箱累計銷量222.49萬TEU（去年同期：343.36萬TEU），同比下降35.2%；冷藏箱累計銷量20.82萬TEU（去年同期：13.86萬TEU），同比增長50.2%。期內，集裝箱板塊實現營業收入430.09億元，淨利潤18.82億元，毛利率略有下降至13.38%。物流服務業務方面: 期內，該業務實現營業收入人民幣267.93億元，同比下降14.64%；淨利潤為人民幣3.64億元，同比下降16.65%，符合行業趨勢變化。中集世聯達主動調整業務架構，整合業務資源，期內海運業務自攬貨量同比增長6%，港口物流業務的二手箱交易、倉儲分撥創歷史新高，行業物流業務聚焦新能源、汽車、工程項目等重點領域鞏固細分優勢。2025年，中集世聯達在中國國際貨運代理協會發佈的"貨代物流企業綜合榜"中連續3年位列前五。道路運輸車輛方面: 期內，中集車輛實現收入人民幣201.78億元，同比下降3.91%；實現淨利潤人民幣9.27億元，同比下降14.29%。國內市場方面，"星鏈計畫"重塑組織運營模式，中國半掛車業務營業收入同比增長14.65%，毛利率同比提升3.3%。海外市場方面，全球南方市場業務延續高品質增長，期內營收規模達30.9億元，同比增長17.7%，銷量同比大幅提升29.1%，毛利率同比提升1.3個百分點。DTB業務銷量和營收穩健增長,上裝產品總計28,570台，整體收入達人民幣31.84億元，同比增長4.97%，核心產品市場佔有率進一步提升。同時，持續積極擴展新能源產品的研與銷力度，全面構建EV-RT生態圈，深度推進純電動頭掛列車的戰略發展。空港與物流裝備、消防與救援設備方面: 得益於優質訂單釋放結轉，期內實現營業收入人民幣76.19億元，同比增長5.92%；實現淨利潤人民幣2.64億元。空港裝備成功交付西安咸陽國際機場、土耳其安塔利亞機場及蘭州機場等智慧登機橋專案，亦憑藉自主研發的創新裝配式固定橋，中標南寧機場二期、杭州機場T2/T4連廊兩大重點專案；物流裝備交付國內化工行業石化煉化專案一體化項目配套自動化立體倉庫；消防與救援設備業務推動國產製造海外突圍，同時重點佈局智慧消防與無人消防車前沿領域。二、在能源領域能源、化工及液態食品裝備業務方面，實現營業收入人民幣271.92億元，同比上升6.31%；淨利潤大幅增長42.15%至人民幣10.40億元。其中，中集安瑞科實現營業收入人民幣263.26億元，同比增長6.3%。具體來看，清潔能源分部水上與陸上業務同步發力，在高壓、低溫等關鍵裝備的市場持續獲得領先份額，同時精准抓住天然氣在水陸交通、發電等領域的應用增長機遇，同時積極開拓特種工業氣體設備在高新科技產業的新興增長空間。2025年，該分部新簽訂單達222.29億元，創歷史新高，其中水上清潔能源相關業務截至2025年底在手訂單超人民幣190億元，造船業務已排產至2028年。報告期內成功投產第二個焦爐氣綜合利用項目——淩鋼一期項目、建成國內首個量產生物甲醇項目並實現投產；化工環境分部市場份額穩居首位，醫療設備部件業務、後市場服務業務保持穩健增長。截至2025年年末的在手訂單同比增長36.27%至12.76億元，為後期發展提供較好保障；液態食品分部盈利能力穩健，毛利率較同期提升至21.7%。海洋工程方面，主要經營主體中集來福士成功實現從"建造主導"向"設計+建造+集成"一體化服務的戰略轉型，國內市場穩居領先，躋身國際海工市場重要新生力量。報告期內實現營業收入人民幣179.38億元，同比增長8.35%；淨盈利人民幣10.57億元，成集團第二大盈利板塊。得益於全球海工市場復蘇，以FPSO/FLNG為代表的高端油氣裝備需求強勁，同時全行業正加速向綠色化與智慧化轉型，新能源裝備訂單保持穩定增長。年內，公司新簽合同訂單12.0億美元，包括12+8條集裝箱支線船、2條海工特種船及其它模組訂單。截止2025年底，海洋工程板塊累計持有在手訂單價值50.9億美元，其中油氣、特種船訂單占比約為7:3，其中龍口基地已排產至2030年。海工資產運營管理業務方面，公司持續發揮現有專案經驗和業務能力，借助優異的海工平臺運營管理能力，提高資產上租率。報告期內，第六代半潛鑽井平臺"仙境煙臺"完成續租簽約；超深水半潛鑽井平臺"藍鯨一號"與國際客戶簽署新租約；半潛式起重/生活平臺"Blue Gretha（原華電中集01）"與國際客戶簽署新租約；其他多座平臺也在通過多種管道積極參與市場招標，尋求資產處置及租賃等業務機會。報告期內，上租半潛鑽井平臺及自升式鑽井平臺的平均日費率均實現同比增長。未來發展和展望集團管理層表示："2026年是‘十五五’規劃開局之年，集團將以全新升級的品牌標誌為起點，緊緊圍繞‘固本強基、開拓創新、提質增效’，以更加積極主動的戰略姿態，在複雜變局中育新機、開新局，努力建設‘高品質的、受人尊敬的世界一流企業’。"關於中國國際海運集裝箱（集團）股份有限公司中集集團是全球領先的物流及能源行業設備及解決方案供應商，產業集群主要涵蓋物流領域及能源行業領域，龍頭市場地位持續鞏固。在物流領域，本集團仍然堅持以集裝箱製造業務為核心，孵化出道路運輸車輛業務、空港與物流裝備/消防與救援設備業務，輔之以物流服務業務及迴圈載具業務提供物流專業領域的產品及服務；在能源行業領域，本集團主要從能源/化工/液態食品裝備業務、海洋工程業務方面開展；同時，本集團也在不斷開發新興產業並擁有服務本集團自身的金融及資產管理業務。作為一家為全球市場服務的多元化跨國產業集團，中集在亞洲、北美、歐洲、澳洲等地區擁有300余家成員企業，共擁有4家上市公司，客戶和銷售網路分佈在全球100多個國家和地區。2025年，本集團業績實現營業收入人民幣1566億元，位列2025《財富》中國500強榜單第154名。在集裝箱標準幹箱、冷藏箱、化工罐箱、半掛車等核心產品領域連續多年保持全球第一。如欲獲得更多資訊，請流覽https://www.cimc.com/。 Copyright 2026 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com

Financial HighlightsRMB 100 millionFor the 12 months ended 31 DecemberChange (%)20252024Revenue1566.111,776.64-11.85% Profit28.4265.53-56.64% Profit before Tax28.1665.95-57.30% Gross Profit194.95222.47-12.37% Gross Profit Margin12.45%12.52%-0.07pct Net Profit13.3741.95-68.12% Net Profit Attributable to Shareholders and Other Equity Holders2.2129.72-92.57% Net cash flows from operating activities 185.1492.6499.86% Dividend per share (RMB/share, tax inclusive)RMB 0.179RMB 0.176N/A Total dividend payout9.399.45-0.60% Performance Highlights1. Solid operating core segments with resilient high-quality development: In 2025, the Group achieved revenue of RMB 156.611 billion, net profit of RMB 1.337 billion, and maintained a gross profit margin of 12.45%, with a balanced domestic and overseas revenue structure.2. Dual improvement in cash flow and financial quality, with significantly enhanced risk resilience: Net cash flows from operating activities increased substantially by 99.86% to RMB 18.514 billion, while the cash and cash equivalents as of the end of the Year reached RMB 24.3 billion; the scale of interest-bearing debt decreased by RMB 4.7 billion year-on-year (“YoY”) to RMB 34.4 billion, and net interest expenses decreased by approximately RMB 730 million YoY, with the financial structure continuing to be optimized.3. Cash dividends and share buybacks implemented in parallel to reward investors: The Group proposes a cash dividend of RMB 0.179 per share (tax inclusive) for 2025. Together with multiple rounds of H-share and A-share buyback plans launched during the Year, the total proposed dividend and completed buybacks for 2025 amounted to RMB 1.852 billion.4. Significant improvement in profitability of energy-related businesses, becoming a key growth driver of the Group: Net profit of the offshore engineering segment and the financial and asset management segment (primarily drilling platform leasing) increased by approximately RMB 1.212 billion in total, while the energy, chemical and liquid food equipment segment increased by RMB 308 million. Among them, the gross profit margin of the offshore engineering segment increased significantly by 5.72 percentage points to 14.83%. Orders on hand for offshore engineering and energy, chemical and liquid food equipment reached US$5.09 billion and RMB 29.75 billion, respectively, with certain shipyards’ production schedules extending to 2030.5. Logistics-related businesses continued to serve as the Group’s “ballast stone”: During the Year, businesses such as container manufacturing and road transportation vehicles were affected by exchange rate fluctuations and cyclical changes, resulting in pressure on gross profit margins and profitability. However, the core segments remained solid, and the Group’s competitive advantages in the industry continued to be consolidated. Core products such as standard dry containers, reefer containers, tank containers and semi-trailers have maintained the world’s No.1 position for many consecutive years.6. Breakthroughs in both technology and orders in key businesses, with competitiveness highly recognised: In the high-end offshore engineering equipment sector, CIMC Raffles successfully developed the most complex products in the offshore industry, including FPSO/FLNG, becoming the only enterprise in China with dual-project EPCI general contracting capabilities; in the modular data center sector, the Group providing technical and manufacturing delivery services of prefabrication data center to industry customers exceeding 300MW, leading new transformation in computing power infrastructure.HONG KONG, Mar 26, 2026 - (ACN Newswire via SeaPRwire.com) – China International Marine Containers (Group) Co., Ltd. (“CIMC Group” or the “Group”, stock code: 000039.SZ/02039.HK) is pleased to announce the audited annual results for the 12 months ended 31 December 2025 (the “Year”).The Group’s management stated, “In 2025, profound global changes unseen in a century accelerated, and the global economy demonstrated resilience amid volatility. Positioned in an era of both opportunities and challenges, the Group closely adhered to the strategic theme of “accelerating the construction of new growth drivers and focusing on promoting high-quality development”. While stabilising its operating fundamentals, the Group further deepened its forward-looking strategic layout in the energy business and achieved fruitful results. For the year of 2025, the Group recorded revenue of RMB 156.61 billion and net profit of RMB 1.34 billion. Cash flows from operating activities increased significantly by 99.9% to RMB 18.51 billion, with the asset structure continuously optimized and risk resilience further enhanced.”In particular, to sincerely reward investors, CIMC Group proposes to distribute a cash dividend of RMB 0.179 per share (tax inclusive) to all shareholders for 2025, amounting to a total proposed cash dividend of RMB 939 million (tax inclusive). Meanwhile, the Group implemented share buybacks totalling RMB 913 million during 2025, bringing the combined total to RMB 1.852 billion.Segments Results (RMB 100 million)2025 Business indicatorsRevenueAs % of the total revenueGross profitAs % of the gross profitGross profit marginNet profitContainer manufacturing430.0927.46%57.5529.52%13.38%18.82Road transportationvehicles201.7812.88%32.0616.45%15.89%9.27Energy, chemical, and liquid food equipment271.9217.36%40.2420.64%14.80%10.40Offshore engineering179.3811.45%26.6013.65%14.83%10.57Logistics services267.9317.11%16.708.57%6.23%3.64Airport facilities and logistics equipment/fire safety and rescue equipment76.194.86%15.147.76%19.87%2.64Total of major segments1427.2991.12%188.2996.59%13.19%55.34Core Business Performance1. In logistics field:In the container manufacturing business, during the Year, despite negative supply chain factors such as U.S. tariff policies and geopolitical conflicts, global merchandise trade demonstrated strong resilience. Intra-regional trade, Asia-Europe routes and emerging market routes became the main drivers of incremental growth. Meanwhile, factors such as detours around the Red Sea, port congestion, environmental requirements in shipping and increasing complexity of trade routes reduced transportation efficiency, structurally boosting underlying demand and pushing the global container fleet into a new structural phase. As a result, overall demand for new containers in 2025 remained at a relatively high level, exceeding the average of the past decade. During the Year, the production and sales volume of the Group’s container manufacturing business declined YoY, in line with overall industry expectations, but the Group maintained its global No.1 position. Accumulated sales volume of dry cargo containers reached 2,224,900 TEUs (2024: 3,433,600 TEUs), representing a YoY decrease of 35.2%. Accumulated sales volume of reefer containers reached 208,200 TEUs (same period last year: 138,600 TEUs), representing a YoY increase of 50.2%. During the Year, the container manufacturing segment recorded revenue of RMB 43.009 billion, net profit of RMB 1.882 billion, and a slight decline in gross profit margin to 13.38%.In the logistics services business, during the Year, the segment recorded revenue of RMB 26.793 billion, representing a YoY decrease of 14.64%, and net profit of RMB 364 million, representing a YoY decrease of 16.65%, in line with industry trends. CIMC Wetrans actively adjusted its business structure and integrated resources. During the Year, self-sourced cargo volume increased by 6% YoY, while second-hand container trading and warehousing distribution in port logistics reached record highs. The industry logistics business focused on key sectors such as new energy, automotive and engineering projects to consolidate its niche advantages. In 2025, CIMC Wetrans ranked among the top five for three consecutive years in the “Comprehensive List of Freight Forwarding and Logistics Enterprises” published by the China International Logistics and Freight Forwarding Association.In the road transport vehicles business, during the Year, CIMC Vehicles recorded revenue of RMB 20.178 billion, representing a YoY decrease of 3.91%, and net profit of RMB 927 million, representing a YoY decrease of 14.29%. In the domestic market, the “Star-Chained Plan” reshaped the organisational and operational model, with revenue from the China semi-trailer business increasing by 14.65% YoY and gross profit margin increasing by 3.3%YoY. In overseas markets, the Global South markets maintained high-quality growth, with revenue reaching RMB 3.09 billion during the Reporting Period, representing a YoY increase of 17.7%, sales volume increasing by 29.1% YoY, and gross profit margin increasing by 1.3 percentage points YoY.The DTB business achieved steady growth in both sales volume and revenue, with a total of 28,570 units of mounted equipment products delivered, generating total revenue of RMB 3.184 billion, representing a YoY increase of 4.97%, with further improvement in market share of core products. Meanwhile, the Group continued to actively expand R&D and sales of new energy products, comprehensively building the EV-RT ecosystem and advancing the strategic development of pure electric tractors and trailers.In the airport facilities and logistics equipment/fire safety and rescue equipment, benefiting from the release and delivery of high-quality orders, the segment recorded revenue of RMB 7.619 billion during the Year, representing a YoY increase of 5.92%, and net profit of RMB 264 million. Airport equipment successfully delivered smart boarding bridges projects for Xi’an Xianyang International Airport, Antalya Airport in Türkiye and Lanzhou Airport, and secured major projects including Phase II of Nanning Airport and corridor projects at Hangzhou Airport T2 and T4 with its independently-developed innovative prefabricated fixed bridge solutions. Logistics equipment delivered automated three-dimensional warehouse systems for supporting the petrochemical and refining integration project in China. The fire safety and rescue equipment business advanced the overseas expansion of domestically manufactured products while focusing on frontier areas such as smart fire safety and unmanned fire trucks.2. In the Energy FieldIn the energy, chemical, and liquid food equipment business, the segment recorded revenue of RMB 27.192 billion, representing a YoY increase of 6.31%, and net profit increased significantly by 42.15% to RMB 1.040 billion. Among which, CIMC Enric recorded revenue of RMB 26.326 billion, representing a y YoY increase of 6.3%.Specifically, the clean energy segment advanced both offshore and onshore businesses, maintaining leading market share in key equipment such as high-pressure and cryogenic equipment, while capturing growth opportunities in natural gas applications in water and land transportation and power generation, and actively expanding into emerging markets for special industrial gas equipment in high-tech industries. In 2025, the segment secured new orders of RMB 22.229 billion, a record high. Among these, orders on hand for offshore clean energy-related business exceeded RMB 19 billion as of the end of 2025, with shipbuilding schedules extending to 2028. During the Year, the second coke oven gas comprehensive utilisation project — Linggang Phase I project — was successfully put into operation, and China’s first domestic mass-production bio-methanol (green methanol) project of CIMC Enric was completed and commenced operation. The chemical and environmental segment maintained its leading market share, while the medical equipment components and after-sales service businesses achieved steady growth. As of the end of 2025, orders on hand increased by 36.27% YoY to RMB 1.276 billion, providing strong support for future development. The liquid food segment maintained stable profitability, with gross profit margin increasing to 21.7% YoY.In the offshore engineering business, the Group’s core operating entity, CIMC Raffles, successfully achieved a strategic transformation from “manufacturing-led” to integrated “design + construction + integration” services, maintaining a leading position in the domestic market and emerging as an important new force in the international offshore engineering market. During the Reporting Period, the segment recorded revenue of RMB 17.938 billion, representing a YoY increase of 8.35%, and net profit of RMB 1.057 billion, becoming the Group’s second-largest profit contributor. Benefiting from the recovery of the global offshore engineering market, demand for high-end oil and gas equipment represented by FPSO/FLNG remained strong, while the industry accelerated its transition toward green and intelligent development, driving steady growth in new energy equipment orders. During the year, the Group secured new contract orders of US$1.20 billion, including 12+8 container feeder vessels, 2 offshore engineering special vessels and other module orders. As of the end of 2025, the accumulated value of orders on hand reached US$5.09 billion, with orders for oil & gas and special vessel accounting for approximately 70% and 30%, respectively. The Longkou base has scheduled production through to 2030.In the offshore engineering asset operation and management business, the Group continued to leverage its existing project experience and business capabilities, enhancing asset utilisation through its strong offshore platform operation and management capabilities. During the Reporting Period, the sixth-generation semi-submersible drilling platform “Deepsea Yantai” completed lease renewal, the ultra-deepwater semi-submersible drilling platform “Blue Whale No.1” signed a new lease with an international client, and the semi-submersible lifting/life platform “Blue Gretha (formerly Huadian CIMC 01)” also secured a new lease with an international client. Other platforms actively participated in market tenders to explore opportunities for asset disposal and leasing. During the Reporting Period, the average daily lease rate of semi-submersible and jack-up drilling platforms both recorded year-on-year increases.Future Development and ProspectsThe Group’s management stated, “The year 2026 marks the beginning of the ‘15th Five-Year Plan’. Starting from a newly upgraded brand identity, the Group will closely focus on ‘consolidating foundations, driving innovation, improving quality and efficiency’, and adopt a more proactive strategic approach to foster new opportunities and open new horizons amid complex changes, striving to build a ‘“becoming a high quality and trustworthy world-class multimodal transport enterprise.”About China International Marine Containers (Group) Co., Ltd.The CIMC Group is a world-leading equipment and solution provider in the logistics and energy industries, with its industry clusters mainly covering the logistics and energy fields, continuously strengthening its leading market position. In the logistics field, the Group continues to adhere to container manufacturing as its core business, based on which it has incubated the road transportation vehicles business and the airport facilities and logistics equipment / fire safety and rescue equipment business, supplemented by the logistics services business and recycled load business, providing products and services in the professional logistics field. In the energy field, the Group is principally engaged in the energy, chemical and liquid food equipment business and the offshore engineering business. Meanwhile, the Group continues to develop emerging industries and possesses financial and asset management businesses that serve the Group itself. As a diversified multinational industrial group serving the global market, CIMC has over 300 member enterprises across Asia, North America, Europe, and Australia, with a total of four listed companies, and customers and sales networks covering more than 100 countries and regions worldwide. In 2025, the Group recorded revenue of RMB 156.6 billion, ranking 154th on the 2025 Fortune 500 China list. The Group has maintained the world’s No.1 position for many consecutive years in core products such as standard dry containers, reefer containers, tank containers and semi-trailers. For more information, please visit http://www.cimc.com/. Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

香港, 2026年3月26日 - (亞太商訊 via SeaPRwire.com) - 3月26日，中國生物製藥有限公司公佈 2025 全年業績。年內實現營業收入318.3 億元（人民幣，下同），按年增長 10.3%；經調整Non-HKFRS歸母淨利潤45.4 億元，按年增長 31.4%，連續四個財報期維持雙位數增長，整體表現明顯優於行業平均水平。集團最核心亮點在於創新產品商業化持續放量。2025 年創新產品收入達152.2 億元，按年大增 26.2%，規模處於行業前列，高增速反映創新轉型成效顯著，亦為業績提供可持續支撐。2023‑2025 年三年間，集團累計獲批創新產品 16 款，其中國藥 1 類創新藥達 7 款，成果轉化效率領先行業，成為帶動業績增長的關鍵動力。年內集團再添 4 款創新藥獲國家藥監局（NMPA）批准上市，包括針對 HER2 肺癌、CDK2/4/6 抑制劑、重組七因子及獲 FDA 批準的鎮痛新藥等具突破性產品。核心品種安羅替尼再增 3 項一線適應症，總數擴至 10 項，進一步鞏固抗血管生成藥物領先地位。在腫瘤、肝病 / 心血管代謝、呼吸 / 自免、外科 / 鎮痛四大核心領域，公司已建立完整產品矩陣，支撐長期穩健增長。董事會主席謝其潤表示，連續四期雙位數增長驗證集團在創新研發、BD 合作及併購整合的長期佈局成效。2026 年是集團全面國際化的新起點，年初重磅對外授權項目成為重要里程碑，為創新管線打開全球估值空間。研發方面，集團維持高強度投入，2025 年研發開支達58.7 億元，按年增長逾 15%，佔收入比重 18.4%，雙雙創歷史新高。目前已搭建小分子、ADC、siRNA、蛋白降解劑等多個核心技術平台，於上海、北京、廣州等地設立研發中心，研發團隊超 2900 人，推進臨床項目超 130 個。透過 AI 技術賦能研發全流程，PCC 發現時間提速超 50%，臨床篩選週期縮短約 30%，研發質效顯著提升。首席執行長謝承潤指出，集團在鞏固本土優勢之餘，堅定推進國際化與數碼化戰略，多項重磅創新資產已具備全球競爭力。2026 年開局表現強勢：1 月以 12 億元收購 siRNA 技術平台赫吉亞；2 月 FIC 新藥羅伐昔替尼獲批，並將全球權益授權予賽諾菲，交易潛在總金額超 15 億美元，開啟國際化第二增長曲線。展望未來三年（2026‑2028），集團創新管線將進入密集收穫期，預計逾 20 款創新藥或新適應症有望上市，涵蓋多個 FIC/BIC 潛力品種。於腫瘤、呼吸、肝病代謝、外科鎮痛領域均有重磅品種推進，包括 CLDN18.2 ADC、雙抗、PDE3/4 抑制劑、pan‑PPAR 激動劑等，管線梯次清晰、儲備充足。整體而言，中國生物製藥已由仿製驅動成功轉向創新驅動，憑藉高研發投入、高效商業化與國際化佈局，進入高質量增長階段。隨著創新產品持續放量、管線逐步兌現，集團長期增長動能充足，在港股藥板塊中具備突出配置價值。 Copyright 2026 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com

Financial Highlights (Audited)(HKD Thousand)Year ended31 December20252024Revenue170,011271,372Gross Profit53,382104,720Profit Attributable to Owners of the Company13,68833,440Basic Earnings per Share (HK cents)0.972.37HONG KONG, Mar 26, 2026 - (ACN Newswire via SeaPRwire.com) - Dynasty Fine Wines Group Limited (“Dynasty” or “the Group”) (Stock Code: 00828), a premier grape winemaker in China, today announced its audited annual results for the year ended 31 December 2025 (“the Year”).In 2025, due to the impact of macroeconomy as well as weak demand in wine consumer market in the PRC, the Group’s sales of medium to high-end products significantly declined, resulting in a 37% year-on-year decrease in revenue to HK$170.0 million. In addition, due to the decline in sales revenue and gross margin, as well as an increase in loss allowances for trade receivables owing to extended repayment from certain distributors, the profit attributable to owners of the Company decreased by 59% year-on-year to approximately HK$13.7 million, although such decrease in profit was already partly offset by a net gain on compensatory surrender recognised during the year. Earnings per share of the Company was HK0.97 cents per Share.With strengthened marketing effort for dry white in coastal region and the launch of new white wine and sparkling wine products, sales of white wine products served as the Group’s primary revenue contributor. Sales of red and white wines products accounted for approximately 39% and 54% of the revenue respectively for the year (2024: approximately 41% and 56% respectively). The gross margin of red wine products and white wine products in 2025 were 25% and 35% respectively (2024: 36% and 41% respectively). The overall gross profit margin decreased to 31% in 2025 (2024: 39%), mainly due to change in product mix with more products with lower prices and margin in response to market dynamics and needs during the year.The Group has been actively pursuing innovation, embracing the “5+4+N” product strategy, with “N” standing for developing various customised products and continuously creating new products to meet the diverse needs of different Chinese consumer groups. During the year, the Group launched a new gift set product, i.e. Dynasty Chinese Zodiac Commemorative Dry Red Wine for the Yi Si Year of Snake, integrating with the Chinese zodiac culture and the leading rise of Chinese-style fashionable products, by presenting the zodiac culture in a youthful visual language to attract potential consumers. In addition, based on its existing high-quality products, the Group continues to introduce new products and promote product upgrades. The Group participated in the 112th China Food & Drinks Fair in March 2025, introducing new products such as Tianyang Tea-flavoured wine series, Dynasty Baifu VSOP brandy, etc., to further improve its product matrix and provide consumers with diverse consumption choices. Breaking through from the constraints of traditional wine, this tea-flavoured wine series, with its core concept of “tea and wine fusion,” has captured market attention with its unique craftsmanship. During the China Food & Drinks Fair, the Group also held wine-tasting events, where the new wines from Dynasty Ningxia Winery won industry praise for their unique flavor and exquisite craftsmanship. In the second half of the year, the Group also introduced new products “Hi” tea-flavoured wine series in response to the market need, which are very suitable for ready-to-drink scenarios among young consumers.In addition to enriching the product matrix, the Group has been closely cooperating with distributors, pressing ahead with its marketing campaign, accelerating the innovation of consumption scenarios, and enhancing and strengthening the wine cultural experience. The Group held its national tour tasting and business events, new products launch ceremonies at various exhibitions and wine fairs, as well as promotion activities for the 20th anniversary of listing in Hong Kong, during which the Group actively promoted its latest product mix that covered all product lines.During the year, two joint venture companies approved by the Group were established in February 2025, for the manufacturing and sales of yellow wine and Chenpi wine and trading of sauce-flavour baijiu products nationwide in the PRC respectively. For the yellow wine project, installation and testing of production equipment of a manufacturing plant with a tank capacity of 3,000 tonnes of yellow wine and special yellow wine – Chenpi wine in Jiangsu is expected to be completed in the second half of 2026. Upon completion of the project, the Group will be able to produce special yellow wine – Dongtai Chenpi Wine which allows the Group to effectively expand product categories, seize development opportunities in the Chinese yellow wine industry. The project expansion aims to effectively implement Dynasty’s strategic plan, further improving the industrial layout, expanding category tracks, tapping into industry potential, creating new performance growth points, and realising Dynasty Group’s transformation into a full category, full industry-chain enterprise. For the sauce-flavour baijiu segment, Dynasty sauce-flavour baijiu products, namely ‘Han’, ‘Tang’, ‘Song’ and ‘Ming’ have been newly launched in the core-market in Tianjin and Shanghai and will be further strategically promoted to other regions in 2026. The sauce-flavour baijiu products satisfy the needs of customer groups with different spending habits and contributing to the Group’s business. In the future, the continuous development and expansion of the sauce-flavour baijiu industry and the improvement of the level of customer groups will inevitably and effectively drive the increase in the sales scale of Dynasty wine and related products, thereby enhancing our industry influence and brand awareness.Regarding online sales, the e-commerce team of the Group comprehensively operates online stores itself on the traditional e-commerce platforms, such as JD.com, Tmall and Pinduoduo for product sales, as well as comprehensive innovation on its brand, product categories, and business systems, procedures and models via interest-based e-commerce platforms, including Rednote, Kuai and TikTok. The Group continues investing resources in a timely manner for improvement of the online sales channels and optimisation of online stores interface so as to capture the change of customer consumption behaviour in the PRC. The Group jointly develops exclusive products with leading e-commerce platforms, and promote AI livestreaming models in various channels to increase brand exposure and livestreaming sales, adopts big data analysis to accurately understand consumer demand, and injects strong momentum into the continued expansion of market scale. To establish an online brand matrix, the Group selected and authorised new online distributors during the year. The Group believes that the online platforms not only serve as business-to-customer trading platforms between the Group and the consumers, but also additional marketing and promotion channels for the brand, which can enhance the overall business potential of the Group.During the year, the Group had boasted brilliant results in major wine appraisal competitions. Among the numerous awards, “Dynasty Jin. Y Brandy XO barrel-aged 12 years” has won the Silver Award, at the 2025 International Wine & Spirit Competition (“IWSC”). The competition is considered the international standard for wine and spirits quality. Dynasty Baifu VSOP Brandy, Golden Dynasty Marselan Dry Red Wine, as well as Tianyang Tea Wine series are also awarded at the “2024 Qingzhuo Awards” in respective categories by China Alcoholic Beverages Association. “Dynasty Mengyuan White wine” has also won the Grand Gold Medal at the France International Wine Awards (“FIWA”) China region, Spring 2025 for its excellent quality. In addition, “Dynasty Inherit series – Dry Red Wine” has garnered the Gold Award at the same competition. These wines stood out from other entries for their elegant aroma, smooth body and round taste, and won the awards at the competitions, showing the charm and strengths of Dynasty wines to the country and the world. Dynasty has won the Silver Medal in the Sparkling Wine/China category, the Silver Medal in the Dry Wine/China category, and the Bronze Medal in the Medium/China category for its Dynasty Tianyang Winery Jasmine Sparkling Wine, Dynasty Inherit Series – Dry Red Wine, and Dynasty Inherit Series – Semi Dry White Wine, respectively, at the 2025 Cathay Global Wine & Spirits Awards Asia (“GWSAA”) (formerly known as the Cathay Hong Kong International Wine & Spirit Competition (“HKIWSC”)). This marks the 15th consecutive year that Dynasty products have won awards at the event, demonstrating industry-wide recognition of Dynasty’s exceptional winemaking skill and quality. In addition, “Dynasty Pinyue VSOP brandy” also won the Gold Medal in the brandy category of 2025 China Fine Wine Challenge.Mr. Wan Shoupeng, Chairman of Dynasty, concluded, “Looking ahead to 2026, the Group will continue to focus on market and consumer demand, reinvent consumption scenarios and promote product quality. At the same time, the Group will continue to innovate marketing strategies to stimulate brand vitality, further expand the market share of Dynasty’s products, strengthen Dynasty’s brand image as a representative of domestic wines, and set a benchmark for the Chinese wine industry, with the aim of bringing Dynasty’s superior wines to more consumers in the PRC. The Group will continue to uphold quality, seize the development trend of low-alcohol and younger consumer markets, and proactively develop new marketing prospects through innovation in products categories and consumption scenarios.”About Dynasty Fine Wines Group LimitedDynasty Fine Wines Group Limited was listed on the Main Board of The Stock Exchange of Hong Kong Limited with the stock code 00828 on 26 January 2005. Founded in 1980, Dynasty is the premier grape winemaker in China. It is principally engaged in the production and sale of grape wine products under its reputable “Dynasty” brand. Dynasty is the first Sino-foreign joint venture wine company in China with Tianjin Food Group Limited and the French grape wine giant, Remy Cointreau, as its current major shareholders. The Group produces and sells more than 100 grape wine product series, and introduces imported wine products, providing high-quality and value-for-money grape wines to the full range of consumer groups in China.For media enquiries:Strategic Financial Relations (China) LimitedMs. Anita Cheung Tel: 2864 4827Ms. Gianna Ye Tel: 2864 4837Ms. Hazel Ye Tel: 2864 4893Ms. Chloe Lyu Tel: 2864 4835Email: sprg-dynasty@sprg.com.hk Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

財務摘要 (經審核)（港幣千元）截至十二月三十一日止年度 2025年2024年收入170,011271,372毛利53,382104,720本公司所有者應佔溢利13,68833,440每股基本盈利 (港仙)0.972.37香港, 2026年3月26日 - (亞太商訊 via SeaPRwire.com) - 中國優質葡萄酒生產商王朝酒業集團有限公司(「王朝」或「集團」)(股份代號：00828)今日公佈截至2025年12月31日止（「年內」）經審核之全年業績。2025年，受宏觀經濟和中國葡萄酒消費市場需求疲弱的情況影響，集團中高檔產品銷售下滑，收入較去年同比減少37%至1.70億港元。另外由於銷售收入及毛利率下降，以及部分經銷商延遲還款導致應收賬款虧損撥備增加，本公司所有者應佔溢利較去年同比減少59%至13.7百萬港元，儘管溢利減少部分已被年內確認的補償交出淨收益所抵消。集團每股基本盈利為每股0.97港仙。隨著集團在沿海地區加大對乾白葡萄酒市場的推廣力度，並推出新款白葡萄酒及起泡酒產品，白葡萄酒產品的銷售已成為集團的主要收入來源。紅葡萄酒及白葡萄酒產品的銷售分別佔集團於年內收入的約39%及54%（2024年：分別為約41%及56%）。於2025年，紅葡萄酒產品及白葡萄酒產品的毛利率分別為25%及35%（2024年：分別為36%及41%）。整體毛利率減少至31%（2024年：39%），主要由於年內因應市場動態及需求調整產品組合併降低銷售價格及利潤率。集團積極求新，聚焦「5+4+N產品戰略」，其中「N」代表集團推出N項需求定制，不斷開拓創新產品，以滿足中國不同類型消費群體的多元化需求。年內，集團推出禮盒新品－王朝乙巳蛇年生肖紀念乾紅葡萄酒，與中國生肖文化相融合，引領「國潮風」，以年輕化的視覺語言呈現生肖文化，吸引潛在消費者。此外，基於其現有的優質產品，集團繼續推出新產品並推進產品升級。集團於2025年3月在第112 屆全國糖酒商品交易會上推出天陽茶酒系列、王朝百馥VSOP白蘭地等新品，以進一步完善其產品矩陣，為消費者提供多元的消費選擇。該系列茶香葡萄酒突破傳統葡萄酒的局限，以「茶酒融合」為核心理念，憑藉獨特的釀造工藝迅速獲得市場目光。在全國糖酒商品交易會期間，集團亦舉辦品酒會，而王朝寧夏酒莊的新品憑藉獨特的風味和精湛的釀造工藝，贏得業界的好評。下半年，集團亦因應市場需求，推出全新產品「嗨」茶風味酒系列，非常適合年輕消費者的即飲場景。除了豐富產品矩陣外，集團與經銷商緊密合作，積極推進市場推廣活動，加速創新消費場景，提升及強化葡萄酒文化體驗。集團於各類展覽及葡萄酒博覽會舉行期間，舉辦了全國巡迴品鑒會及招商活動、新品發佈會以及香港上市20週年推廣活動，期間集團大力推廣其全系列的最新產品組合。年內，集團批准設立的兩間合資公司於2025年2月成立，分別從事黃酒及陳皮酒生產及銷售，以及於全國範圍內買賣醬香型白酒產品。對於黃酒項目，江蘇的一座儲罐容量為3,000 噸黃酒及特種黃酒－陳皮酒的生產設備及安裝及測試預期將於2026年下半年完成建設。於項目完成後，集團將能夠生產特種黃酒－東台陳皮酒，讓集團可有效擴展產品品類，把握中國黃酒行業的發展機遇，進一步優化集團產業佈局，拓展品類版圖，實現王朝向全品類、全產業鏈企業的轉型。對於醬香型白酒領域，王朝醬香型白酒產品，即「漢」、「唐」、「宋」、「明」，已於天津及上海核心市場新推出，並將於2026年進一步戰略推廣至其他地區。醬香型白酒產品滿足不同消費習慣的客戶群體的需求，並為集團業務作出貢獻。未來，醬香型白酒產業的持續發展及擴張及客戶群體水平的提升，必將有效推動王朝葡萄酒及相關產品銷售規模的增長，從而提升行業影響力及品牌知名度。電商銷售方面，集團的電商團隊於傳統電商平台全面運營在線商店銷售產品，例如京東商城、天貓商城及拼多多，以及通過興趣電商平台（包括小紅書app、快手app 及抖音app）全面創新品牌、品類、業務體系、流程和模式。集團繼續為改善網上銷售渠道及時投入資源，優化在線商店界面，以把握中國客戶消費行為的變化，與頭部電商平台共同開發專屬產品，並通過多種渠道推廣人工智能直播模型以提升品牌曝光度及直播銷售額，採用大數據分析以精準洞察消費者需求，為市場規模持續擴大注入強勁動力。為建立線上品牌矩陣，集團於年內甄選及開放新店線上經銷商授權。集團相信線上平台不僅是集團與消費者之間的企業對客戶交易平台，亦是品牌新增的市場推廣及宣傳渠道，從而提升集團的整體業務潛力。年內，集團在大型葡萄酒品鑒大賽中屢獲殊榮。在多個獎項中，「王朝錦邑桶藏12年XO白蘭地」榮獲2025年國際葡萄酒與烈酒大賽（「IWSC」）中的銀獎。該比賽被視為葡萄酒和烈酒質量的國際評價標準。王朝百馥VSOP白蘭地、金王朝馬瑟蘭乾紅葡萄酒以及天陽茶酒系列亦於中國酒業協會舉辦的「二零二四年青酌獎」各類別評選中獲獎。「王朝夢園白葡萄酒」亦以其卓越的酒質榮獲2025年春季FIWA法國國際葡萄酒大獎賽中國區金獎。此外，「王朝傳承系列－乾紅葡萄酒」於同一比賽中榮獲金獎。該等葡萄酒因其酒香優雅、酒體順滑和口感圓潤從眾多參賽作品中脫穎而出，並在比賽中獲得獎項，向國家及世界展示了王朝葡萄酒的魅力和實力。王朝旗下產品「王朝天陽酒莊茉莉葡萄起泡酒」、「王朝傳承乾紅葡萄酒」以及「王朝傳承半乾白葡萄酒」分別於2025年度國泰環球葡萄酒及烈酒大獎亞洲（「GWSAA」）（前稱國泰航空香港國際美酒品評大獎（「HKIWSC」））榮獲中國產區品評組別下氣泡酒、乾型酒銀獎殊榮，以及中國產區品評組別下半乾型酒銅獎殊榮。這是王朝產品連續15年於該獎項中獲得佳績，標誌著王朝在葡萄酒釀造技藝與卓越品質方面再次獲得業界的高度認可。此外，「王朝品悅VSOP白蘭地」在2025年中國優質葡萄酒挑戰賽中榮獲白蘭地類別金獎。王朝主席萬守朋先生總結︰「展望2026年，本集團將繼續以市場及消費者需求為導向，重塑消費情景，提升產品質量。同時，本集團將繼續創新市場營銷策略，激發品牌活力，進一步擴大王朝產品的市場佔有率，加強王朝品牌作為國產葡萄酒代表的形象，並為中國葡萄酒行業樹立標桿，將王朝美酒風尚帶給更多的中國消費者。本集團將繼續秉持品質至上，把握低酒度飲品及年輕消費者市場的發展趨勢，並通過產品品類及消費場景的創新，積極開拓新的市場前景。」關於王朝酒業集團有限公司王朝酒業集團有限公司於2005年1月26日在香港聯合交易所有限公司主板上市，股份代號00828。成立於1980年，王朝為中國優質葡萄酒生產商，主要生產及銷售「王朝」商標的葡萄酒產品，是中國第一家中外合資的釀酒企業，主要股東包括天津食品集團有限公司及法國葡萄酒巨頭人頭馬集團。集團產銷葡萄酒産品系列超過100種，及引入進口葡萄酒產品，為國內各消費層提供高質素及物超所值的葡萄酒。新聞垂詢：縱橫財經公關顧問(中國)有限公司張麗雲小姐 電話：2864 4827葉甘霖小姐 電話：2864 4837葉婉鈴小姐 電話：2864 4893呂昕純小姐 電話：2864 4835電郵：sprg-dynasty@sprg.com.hk Copyright 2026 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com

HONG KONG, Mar 26, 2026 - (ACN Newswire via SeaPRwire.com) - The Census and Statistics Department today released the latest external merchandise trade statistics. In February 2026, the total value of merchandise exports increased by 24.7% year-on-year to $408.8 billion. For the first two months of 2026, the total value of exports of goods amounted to $928.3 billion, marking an increase of 29.6% from the same period of last year.Hong Kong Trade Development Council’s Director of Research Bruce Pang said, over the past few months, Hong Kong’s external trade has continued to exhibit clear growth momentum. Although global geopolitical conditions remain tense, underlying demand from the Chinese Mainland and major overseas markets has remained resilient. We maintain a positive outlook, yet remain cautious in regard to Hong Kong’s trade performance.”HKTDC Media Room: https://mediaroom.hktdc.com/enMedia enquiriesPlease contact the HKTDC’s Communications & Public Affairs Department:Jane CheungTel: (852) 2584 4137Email: jane.mh.cheung@hktdc.org Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

NEW YORK, N.Y., Mar 26, 2026 - (ACN Newswire via SeaPRwire.com) - OpenClawd AI today released a security-focused platform update that adds automated skill vetting, verified installer sourcing, and runtime sandboxing to its managed OpenClaw hosting service. The update responds to two converging threats targeting users of the open-source AI agent formerly known as Clawdbot and Moltbot: a large-scale malware campaign inside the official OpenClaw skill marketplace, and a parallel wave of counterfeit installation packages being promoted through search engine results.The numbers are bad enough on their own. Together, they describe a supply chain that is actively hostile to casual users.One in Eight OpenClaw Skills Is Confirmed MaliciousIndependent security researchers recently completed an audit of the ClawHub skill marketplace — the primary distribution channel for third-party OpenClaw plugins. Out of 2,857 published skills, 341 were confirmed as malicious. That is approximately 12% of the entire marketplace.The findings include:Keyloggers and credential stealers deployed through skills that appear to offer legitimate productivity featuresSilent data exfiltration — one widely-downloaded skill was found to instruct the OpenClaw agent to execute curl commands that sent user data to an external server without any notification or consent promptPrompt injection payloads embedded in skill descriptions, designed to override the agent’s safety guidelines and force execution of unauthorized commandsPlaintext credential exposure — a separate audit found that over 280 additional skills were leaking API keys, tokens, and passwords in their source codeA major cybersecurity firm tested a specific ClawHub skill and published the results: nine security findings, including two critical and five high-severity issues. The skill functioned as what the researchers called “functionally malware.” The most widely-downloaded malicious skill on ClawHub was a cryptocurrency stealer.Fake OpenClaw Installers Are Being Promoted by Search EnginesThe marketplace problem is only half the story. A cybersecurity research team discovered that threat actors have published counterfeit OpenClaw installation packages on open-source code repositories. These fake installers mimic the legitimate OpenClaw setup process but instead deliver a malware packer that disables firewall protections and routes network traffic through compromised systems.The attack chain is straightforward: a user searches for “install OpenClaw” or “Clawdbot download.” An AI-powered search engine returns a result linking to the malicious repository. The user follows the instructions. The malware deploys silently.The researcher who discovered the campaign noted that the person who first reported the threat was a technical professional. “If a fellow IT pro is susceptible to this threat,” he said, “then anyone could be.”“There are now two ways to get compromised before you even run your first OpenClaw command,” said Danny Wilson, spokesperson for OpenClawd. “You can install a fake version of the software, or you can install the real version and then add a skill that steals your data. We built this update so that neither path exists on our platform.”What OpenClawd Ships TodayThis update targets both the supply chain and the runtime:Verified installer sourcing — all OpenClawd instances are provisioned from cryptographically signed OpenClaw releases, pulled directly from the official repository. No third-party install paths. No search engine intermediaries.Skill vetting pipeline — third-party skills go through automated static analysis and behavioral testing before activation. Skills flagged for network exfiltration, prompt injection patterns, or credential exposure are blocked by default.Runtime sandboxing — each skill executes in an isolated environment with explicit permission boundaries. A skill that requests network access to an unexpected endpoint triggers a review before execution.Credential isolation — API keys and tokens are stored in encrypted vaults and never exposed in plaintext to skill code or agent logsAutomatic CVE patching — hosted instances track the latest stable OpenClaw release (currently v2026.3.x), with all known vulnerabilities patched before deploymentOpenClawd does not operate its own skill marketplace. Skills available on hosted instances are drawn from the official ClawHub repository after passing the vetting pipeline described above.OpenClawd is not affiliated with the OpenClaw open-source foundation, OpenAI, Peter Steinberger, or any third-party security research firm cited in this release. It is an independent platform built on the open-source Clawdbot codebase. The open-source project remains free at github.com/openclaw/openclaw.Pricing starts with a free tier. Paid plans include dedicated compute, priority security patching, and uptime monitoring. Deploy a secure OpenClaw instance at https://openclawd.ai.Contact:Email: support@openclawd.ai Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

Development Highlights- During the Year, the Group had 4 innovative products approved for marketing by the NMPA, namely, Saitanxin(R) (Culmerciclib Capsules), Hernexeos(R) (Zongertinib Tablets), Putanning(R) (Meloxicam Injection (II)) and Anqixin(R) (Recombinant Human Coagulation Factor VIIa N01 for Injection).- In 2025, the Group’s sales of innovative products reached RMB 15.22 billion, representing a year-on-year increase of 26.2%. In addition, the Group has established multiple R&D centers in Shanghai, Nanjing, Beijing, Guangzhou, and other cities, and has successfully built diversified innovative technology platforms covering small molecules, protein degraders, siRNA, monoclonal/bispecific antibodies, antibody-drug conjugates (ADC), inhalable formulations, transdermal patches and other fields.- As at 31 December 2025, the Group had a total of 39 innovative oncology drug candidates, 10 innovative liver/cardiometabolic drug candidates, 14 innovative respiratory/autoimmune drug candidates, and 6 innovative surgery/analgesia drug candidates in the process of clinical trial application or above. Of these, 1 innovative oncology drug candidate and 2 innovative surgery/analgesia drug candidates are in the marketing application stage; and 13 innovative oncology drug candidates, 1 innovative liver/cardiometabolic drug candidate, 5 innovative respiratory/autoimmune drug candidates, and 1 innovative surgery/analgesia drug candidate are in Phase III clinical trials. Also, 9 innovative oncology drug candidates, 6 liver/cardiometabolic drug candidates, 5 innovative respiratory/autoimmune drug candidates, and 2 innovative surgery/analgesia drug candidates are in Phase II clinical trials. In addition, the Group had a total of 16 innovative oncology drug candidates, 3 innovative liver/cardiometabolic drug candidates, 4 innovative respiratory/autoimmune drug candidates, and 1 innovative surgery/analgesia drug candidate in Phase I clinical trials.- Focus V(R) (Anlotinib Hydrochloride Capsules) is a novel small molecule multi-target tyrosine kinase inhibitor that has been approved for 10 indications. It has several new indications currently in Phase III clinical studies, including first-line non-squamous non-small cell lung cancer and first-line pancreatic cancer, with plans to gradually submit marketing applications within the next two years.- From 2023 to 2025, the Group obtained marketing approval for 7 national category 1 innovative oncology drugs, namely, Saitanxin(R) (Culmerciclib capsule), Hernexeos(R) (Zongertinib table), Yilishu(R) (Efbemalenograstim alfa Injection), Andewei(R) (Benmelstobart Injection), Anboni(R) (Unecritinib Fumarate Capsules), Anluoqing(R) (Envonalkib Citrate Capsules), and Anfangning(R) (Garsorasib Tablets). It also obtained marketing approval for 4 oncology biosimilars, including Anbeisi(R) (Bevacizumab Injection), Delituo(R) (Rituximab Injection), Saituo(R) (Trastuzumab for Injection), and Paletan(R) (Pertuzumab Injection). The sales volume of these products accelerated rapidly in 2025, and they have become important contributors to the Group’s revenue growth.- Tianqing Ganmei(R) (Magnesium Isoglycyrrhizinate Injection) is the fourth-generation of glycyrrhizic acid preparation that has been approved for 3 indications. During the Year, the Group made efforts to strengthen academic promotion, expanding doctor coverage and gaining recognition from experts through academic conferences at all levels, while vigorously exploring new patients to expand into new markets, and actively promoting retrospective research to provide more academic evidence for its clinical use.- TQC3721 (PDE3/4 inhibitor) is a dual PDE3/4 inhibitor currently undergoing Phase III clinical trials in China for the treatment of moderate to severe chronic obstructive pulmonary disease (COPD). The Group is developing a variety of dosage forms of TQC3721: a suspension for inhalation is in Phase III clinical trials, and an inhaled dry powder formulation is in Phase II clinical trials. The different dosage forms are expected to further enhance patient compliance.- Zepolas(R)/Debaian(R) (Flurbiprofen Cataplasms) is the first domestically produced cataplasms approved for marketing in China, ranking first in the market share of topical analgesia for many years. The Group focuses on the development of highpotential regions, further expanding its market coverage and gradually increasing its production capacity to meet the booming market demand, driving the sustained rapid sales growth of Zepolas/Debaian. The second-generation flurbiprofen patch developed by the Group is expected to be approved for marketing within one year. With formulation enhancements, the second-generation product can significantly improve the transdermal absorption of the drug and enhance the adhesiveness of the plaster, thereby improving patient compliance.HONG KONG, Mar 26, 2026 - (ACN Newswire via SeaPRwire.com) – Sino Biopharmaceutical Limited (“Sino Biopharmaceutical” or the “Company”, together with its subsidiaries, the “Group”) (HKEX stock code:1177), a leading innovation-driven pharmaceutical conglomerate in the PRC, has announced its audited financial results for the year ended 31 December 2025 (the “Year”).During the Year, the Group's revenue increased by approximately 10.3% to approximately RMB31.83 billion. Profit attributable to owners of the parent from continuing operations (as reported) was approximately RMB2.34 billion, a year-on-year increase of approximately 22.0%. Basic earnings per share attributable to owners of the parent from the continuing operations were approximately RMB13.02 cents, an increase of approximately 24.0% over last year. Underlying profit attributable to owners of the parent totaled approximately RMB4.54 billion, a year-on-year increase of approximately 31.4%. The Group’s liquidity remained strong, with cash and bank balances classified as current assets of approximately RMB12.18 billion, bank deposits classified as non-current assets of approximately RMB10.25 billion, wealth management products of approximately RMB10.56 billion in total, and total fund reserves of approximately RMB32.99 billion for the Year.The Board of Directors has recommended a final dividend payment of HK5 cents per share (2024: HK4 cents). Together with an interim dividend of HK5 cents already paid, the total dividend for the year amounts to HK10 cents (2024: HK7 cents).Sales: Innovation-driven growth fuels sustained sales momentumDuring the Year, the Group consistently increased investments to enhance R&D quality and efficiency, which led to a marked strengthening of R&D capabilities, driving sustained sales revenue growth and delivering substantial results. Sales of innovative products increased by 26.2% year-on-year to approximately RMB15.22 billion, accounting for approximately 47.8% of the Group’s revenue. If the sales is categorized by therapy field, sales of oncology drugs increased by 22.8% year-on-year to approximately RMB13.18 billion, accounting for approximately 41.4% of the Group's revenue. Sales of surgical/analgesic medications increased by 12.8% year-on-year to approximately RMB5.03 billion, accounting for approximately 15.8% of the Group's revenue.In the field of oncology, the Group has a comprehensive layout in non-small cell lung cancer (NSCLC), covering the full-line treatment of multiple subtypes. Focus V(R) (Anlotinib Hydrochloride Capsules) has been approved for 10 indications, and several new indications are currently in the marketing application or Phase III clinical trial stage. Its combination therapy has demonstrated superior efficacy in the treatment of lung cancer. From 2023 to 2025, the Group obtained approval for and launched a total of 7 national category 1 innovative oncology drugs and 4 oncology biosimilars. The sales volume of these products accelerated rapidly in 2025, and they have become important contributors to the Group’s revenue growth.In the field of surgery/analgesia, Zepolas(R)/Debaian(R) (Flurbiprofen Cataplasms) have ranked first in market share of topical analgesia for many years. The second-generation flurbiprofen patch is anticipated to receive marketing approval within the year and is expected to strengthen its market leadership through this dosage form upgrade. Meanwhile, Putanning(R) (Meloxicam Injection (II)), China’s first once-daily long-acting analgesic NSAIDs injection, was approved for marketing by the NMPA and the FDA in May 2025 and has been included in the NRDL in 2025. It is expected to become another blockbuster product for the Group in pain management area.R&D: Technology-driven advancements significantly enhance R&D quality and efficiency R&D innovation has always been the key driving force of the Group. The Group has established multiple R&D centers in places including Shanghai, Nanjing, Beijing, and Guangzhou, and has successfully built diversified innovative technology platforms covering such fields as small molecules, protein degraders, siRNA, monoclonal/bispecific antibodies, antibody-drug conjugates (ADC), inhalation formulations, and transdermal patches. For the year ended 31 December 2025, the Group’s total R&D investment amounted to approximately RMB 6.32 billion, accounting for approximately 19.8% of Group revenue.The Group also attaches tremendous importance to the protection of intellectual property rights and actively files patent applications to enhance its core competitiveness. During the Year, the Group filed 1,167 new patent applications and received 273 patent grants. As at the end of the Year, the Group had accumulated 5,724 valid patent applications and obtained 2,120 valid patent grants.Prospects: Focusing on innovation and firmly promoting internationalization strategyLooking ahead, the Group will continue to focus on innovation and remain deeply committed to four core therapeutic areas – oncology, liver / cardiometabolic diseases, respiratory/autoimmune diseases, and surgery/analgesia. It will leverage AI to deeply empower the entire R&D process and continuously strengthen its R&D and innovation capabilities to drive steady business growth. Over the next three years (2026-2028), the Group’s innovation pipeline is expected to experience another wave of explosive growth, with nearly 20 national category 1 innovative drugs expected to be approved for marketing, including multiple blockbuster products with first-in-class (FIC) and best-in-class (BIC) potential. It is expected that by the end of 2028, the total number of innovative products launched by the Group will be around 40, positioning them as the core driver of business growth.At the same time, the Group will firmly advance its internationalization strategy. In February 2026, the Group announced that it had granted Sanofi an exclusive worldwide license to develop, manufacture, and commercialize Rovadicitinib, with the right to receive payments of up to US$1.53 billion, plus tiered royalties of up to double digits based on annual net sales of Rovadicitinib. Going forward, out-licensing will become another important source of revenue for the Group, continuously injecting strong, new momentum into its performance growth and formally launching a second growth curve supported by revenue from internationalization. In addition, the Group remains committed to adhering to the "win-win cooperation" philosophy and is dedicated to building an open and diverse innovation ecosystem. Through in-depth cooperation with the world's leading pharmaceutical companies, biotechnology firms and scientific research institutions, the Group is accelerating the aggregation of high-quality global resources, promoting the co-creation and sharing of innovative outcomes, and continuously strengthening its market leadership. Through the integration of high-quality resources such as LaNova Medicines and Hygieia, the Group has significantly strengthened its R&D capabilities in cutting-edge fields, including tumor immunology and siRNA.Looking ahead, the Group will continue to drive innovation through its dual engines of internal R&D and strategic cooperation, accelerate its development through internationalization, and make steady progress towards its strategic goal of becoming a world-class innovative pharmaceutical company.For detailed information on the Group’s results for the Year, please refer to the official announcements uploaded by the Group to the Hong Kong Stock Exchange website and its official website.About Sino Biopharmaceutical Limited (HKEX:1177)Sino Biopharmaceutical Limited, together with its subsidiaries, is a leading, innovative R&D-driven pharmaceutical group in China. Its business covers the entire industrial chain, including R&D platforms, intelligent manufacturing, and a robust sales system. Its products encompass a wide range of biologics and chemical drugs, with a strong presence in four core therapeutic areas: oncology, liver/cardiometabolic diseases, respiratory/autoimmune diseases, and surgery/analgesia. The company was listed on the Hong Kong Stock Exchange in 2000, was included as a constituent of the MSCI China Index in 2013, became a constituent of the Hang Seng Index in 2018, and was added to the Hang Seng Stock Connect Biotech 50 Index and the Hang Seng China (Hong Kong-listed) 25 Index in 2020. The company has been named among the "Top 50 Global Pharmaceutical Companies" by the authoritative U.S. magazine Pharm Exec for seven consecutive years, and has been recognized as one of the "Top 50 Best Companies in Asia" by Forbes Asia for three consecutive years.For more information, please visit: www.sbpgroup.com Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

重點成果- 年內，集團共有4個創新產品獲NMPA批准上市，分別為賽坦欣(R)（庫莫西利膠囊）、聖赫途(R)（宗艾替尼片）、普坦寧(R)（美洛昔康注射液(II)）和安啟新(R)（注射用重組人凝血因子VIIa N01）。- 2025年，集團創新產品收入達到人民幣152.2億元，同比增長26.2%。此外，集團已在上海、南京、北京、廣州等地建立多個研發中心，並成功構建了涵蓋小分子、蛋白降解劑、siRNA、單抗／雙抗、抗體偶聯藥物（ADC）、吸入製劑、透皮貼劑等領域的多元化創新技術平台。- 截至2025年12月31日，集團共有39個腫瘤領域、10個肝病╱心血管代謝領域、14個呼吸╱自免領域、和6個外科╱鎮痛領域的創新候選藥物處於臨床申請及以上開發階段。其中，1個腫瘤領域、2個外科╱鎮痛領域產品處在上市申請階段；13個腫瘤領域、1個肝病╱心血管代謝領域、5個呼吸╱自免領域、1個外科╱鎮痛領域的創新候選藥物處於臨床III期，9個腫瘤領域、6個肝病╱心血管代謝領域、5個呼吸╱自免領域、2個外科╱鎮痛領域的創新候選藥物處於臨床II期，另有16個腫瘤領域、3個肝病╱心血管代謝領域、4個呼吸╱自免領域、1個外科╱鎮痛領域的創新候選藥物處於臨床I期。- 福可維(R)（鹽酸安羅替尼膠囊）是一款新型小分子多靶點酪氨酸激酶抑制劑，目前已獲批10項適應症，其一線非鱗狀非小細胞肺癌、一線胰腺癌等多項新適應症正在開展III期臨床研究，預計未來兩年將逐步遞交上市申請。- 2023-2025年，集團共有7款腫瘤領域的國家1類創新藥獲批上市，分別為：賽坦欣(R)（庫莫西利膠囊）、聖赫途(R)（宗艾替尼片）、億立舒(R)（艾貝格司亭α注射液）、安得衛(R)（貝莫蘇拜單抗注射液）、安柏尼(R)（富馬酸安奈克替尼膠囊）、安洛晴(R)（枸櫞酸依奉阿克膠囊）和安方寧(R)（格索雷塞片）；以及4款腫瘤領域的生物類似藥獲批上市，分別為：安倍斯(R)（貝伐珠單抗注射液）、得利妥(R)（利妥昔單抗注射液）、賽妥(R)（注射用曲妥珠單抗）和帕樂坦(R)（帕妥珠單抗注射液）。該等產品在2025年快速放量，成為集團收入增長的重要貢獻品種。- 天晴甘美(R)（異甘草酸鎂注射液）是第四代甘草酸製劑，目前已獲批3個適應症。集團年內著力加強學術推廣，透過各層級的學術會議增強了醫生覆蓋和專家認可，同時大力發掘新患者拓展新市場，並積極推進回顧性研究，為其臨床使用提供更多的學術證據。- TQC3721（PDE3／4抑制劑）是一款PDE3／4雙重抑制劑，目前正在中國開展III期臨床試驗，用於治療中重度慢性阻塞性肺病（COPD）。集團正在開發TQC3721的多種劑型：吸入用混懸液位於III期臨床階段，吸入粉霧劑位於II期臨床階段，有望透過多種劑型進一步提升患者的依從性。 - 澤普思(R)／得百安(R)（氟比洛芬凝膠貼膏）是中國首個獲批上市的國產凝膠貼膏，連續多年蟬聯外用鎮痛市場份額第一位。集團聚焦高潛力地區開發，深入拓展市場覆蓋，並逐步擴大產能以滿足市場的旺盛需求，推動澤普思／得百安銷售額持續快速增長。集團開發的第二代氟比洛芬貼劑預計將在年內獲批上市，透過劑型升級，二代產品可顯著提高藥物透皮吸收度，增強貼膏粘附性，從而提升患者的依從性。 香港, 2026年3月26日 - (亞太商訊 via SeaPRwire.com) - 中國領先的創新研發驅動型醫藥集團-中國生物製藥有限公司（「中國生物製藥」或「公司」，連同附屬公司統稱「集團」）（股票編號：1177）公佈截至2025年12月31日止12個月（「年內」）之經審核財務業績。年內，集團收入增長約10.3%至約318.3億元（人民幣，下同）。來自持續經營業務之歸屬於母持有者盈利（財務報表所示）約23.4億元，按年增長約22.0%。來自持續經營業務之歸屬於母公司持有者盈利計算之每股基本盈利約人民幣13.02分，較去年增加約24.0%。歸屬於母公司持有者之基本溢利約45.4億元，按年增長約31.4%。集團流動資金保持充裕，年內有計入流動資產之現金及銀行結餘約121.8億元、計入非流動資產之銀行存款約102.5億元，理財管理產品總額約105.6億元，資金儲備總額約329.9億元。董事會建議派發末期股息每股5港仙（2024年：4港仙），連同已派發中期股息每股5港仙，全年合共派發股息每股10港仙（2024年：7港仙）。銷售：創新引領，銷售動能持續釋放年內，集團持續加大投入以提升研發質效，研發實力顯著增強，驅動銷售收入持續增長，成果豐碩。年內，創新產品之收入同比增加26.2%，達約152.2億元。至於分治療領域，抗腫瘤用藥之收入同比增加22.8%，達約131.8億元，佔集團收入約41.4%。外科／鎮痛用藥之收入同比增加12.8%，達約50.3億元，佔集團收入約15.8%。腫瘤領域，集團全面佈局非小細胞肺癌領域，覆蓋多種分型的全線治療，福可維(R)（鹽酸安羅替尼膠囊）已獲批10項適應症，多項新適應症處於上市申請或III期臨床階段，其聯合療法在肺癌治療中展現出優效。2023年至2025年間，集團共有7款腫瘤領域的國家1類創新藥以及4款腫瘤領域的生物類似藥獲批上市，該等產品在2025年快速放量，成為集團收入增長的重要貢獻品種。於外科╱鎮痛領域，澤普思(R)／得百安(R)（氟比洛芬凝膠貼膏）連續多年蟬聯外用鎮痛市場份額第一位，第二代氟比洛芬貼劑預計將在年內獲批上市，有望透過劑型升級鞏固市場領先地位。同時，中國首款一日一次長效鎮痛NSAIDs注射液普坦寧(R)（美洛昔康注射液（II））已於2025年5月獲得NMPA和FDA的上市批准，並已被新增納入2025年國家醫保藥品目錄，有望成為集團鎮痛領域的又一款重磅產品。研發：技術築基，研發質效顯著提升研發創新始終是集團的核心驅動力，集團目前已在上海、南京、北京、廣州等地建立多個研發中心，並成功構建了涵蓋小分子、蛋白降解劑、siRNA、單抗／雙抗、抗體偶聯藥物（ADC）、吸入製劑、透皮貼劑等領域的多元化創新技術平台。截至二零二五年十二月三十一日止年度，研發總投入約人民幣63.2億元，佔集團收入約19.8%。集團亦重視保護知識產權，積極申報各項專利，以提高核心競爭力。年內，集團提交專利申請1,167項、獲得專利授權273項。截至年末，集團累計有效專利申請達5,724項，累計有效專利授權達2,120項。展望：聚焦創新，堅定推進國際化戰略展望未來，集團將繼續聚焦創新，深耕腫瘤、肝病／心血管代謝、呼吸／自免、外科／鎮痛四大核心治療領域，以AI深度賦能研發全流程，持續強化創新研發能力推動業績穩步增長。預計未來三年（2026-2028年），集團創新管線將迎來新一輪爆發式增長，預計近20款國家1類創新藥有望獲批上市，涵蓋多款具備全球同類首創 (FIC) ／同類最佳 (BIC) 潛力的重磅產品。預計至2028年底，集團上市創新產品總數將達到近40款，成為驅動業績增長的核心引擎。同時，集團堅定推進國際化戰略。2026年2月，集團宣佈授予Sanofi在全球範圍內開發、生產及商業化羅伐昔替尼的獨家許可，並有權獲得最高15.3億美元的付款，以及基於羅伐昔替尼年度淨銷售額的高達雙位數的銷售提成。未來，對外授權合作將成為集團的又一重要收入來源，持續為業績增長注入強勁新動能，正式開啟以國際化收入為支撐的第二增長曲線。此外，集團始終秉持「合作共贏」理念，著力構建開放多元的創新生態體系。透過與全球頂尖藥企、生物科技公司及科研機構的深度合作，集團正加速彙聚全球優質資源，推動創新成果的共創共享，持續鞏固市場領導地位。透過整合禮新醫藥、赫吉亞等優質資源，集團在腫瘤免疫及siRNA等前沿賽道的研發實力顯著增強。未來，集團將繼續以自主研發與戰略合作雙引擎驅動創新，以國際化加速發展，向世界級創新醫藥企業的戰略目標穩步邁進。有關集團本年度詳細業績資料，請參閱集團上載至香港聯合交易所及官網之正式公告。有關中國生物製藥有限公司（股票編號：1177）中國生物製藥，連同其附屬公司，是中國領先的創新研究和研發驅動型醫藥集團，業務覆蓋醫藥研發平台、智慧化生產和強大銷售體系全產業鏈。產品包括多種生物藥和化學藥，在腫瘤、肝病／心血管代謝、呼吸／自免、外科／鎮痛四大治療領域處於優勢地位。公司於2000年在香港聯交所上市，2013年入選MSCI全球標準指數之中國指數成分股；2018年入選恒生指數成分股；2020年入選恒生滬深港通生物科技50指數成分股、恒生中國(香港上市)25指數。中國生物製藥連續七年榮登美國權威雜誌《製藥經理人》發佈的「全球製藥企業TOP50」，連續三年獲評《福布斯》(亞洲) 「亞太最佳公司50強」。有關中國生物製藥的進一步資料，請瀏覽: www.sbpgroup.com Copyright 2026 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com

佛羅里達州西棕櫚灘, 2026年3月26日 - (亞太商訊 via SeaPRwire.com) - 由1890年成立的美國馬球協會（USPA）所授權的官方運動品牌 U.S. Polo Assn.，今日宣布推出全球馬球衫宣傳活動「源自賽場的經典」。這項全球性活動旨在向標誌性的馬球衫致敬，彰顯其純正的運動淵源，以及它如何演變為全球最歷久彌新的時尚經典之一。U.S. Polo Assn. 全球品牌大使、6級美國職業馬球選手尼科·埃斯科巴（Nico Escobar）身著馬球白裝與經典海軍藍 U.S. Polo Assn. 馬球衫，騎乘愛駒觀賽，展現「源自賽場的經典」精神U.S. Polo Assn. 模特兒身著馬球衫，於南卡羅來納州查爾斯頓參與 2026 春夏全球系列攝影「馬球衫：源自賽場的經典」宣傳影像，由 U.S. Polo Assn. 模特兒演繹Polo衫的起源可追溯至馬球場，其設計深受運動動作、競技精神以及這項賦予其名稱的運動所塑造。自問世之初，Polo衫便以實用為本，由追求賽場表現的球員們所穿著。時至今日，U.S. Polo Assn. 不僅將這款歷久不衰的經典視為時尚單品，更視其為源自運動、並由全球數代球員與消費者共同傳承的標誌性象徵。馬球衫是擁有逾百年歷史的最具代表性經典單品之一，以其獨特的運動與時尚融合而著稱。最初採用透氣的平紋針織面料、柔軟的領口及輕量結構，以滿足競技運動的需求；如今已演變為永恆的經典單品，既適合展現休閒優雅，亦是理想的生活休閒服飾。Polo衫的起源可追溯至馬球運動員，其誕生源於這項運動的實際需求。馬球運動員為在比賽中更好地應對高溫、動作與風勢，對長袖棉質襯衫進行了改良。這些以功能性為導向的運動改裝，正是日後Polo衫的雛形。20世紀初，隨著馬球運動日益普及，運動員們協助將這些功能性元素正式化，進一步鞏固了Polo衫與這項運動及其功能性設計之間的連結。多年來，馬球衫已成為全球休閒運動服飾的基石，象徵著學院風、奢華休閒文化與當代運動休閒風，從馬球場到大學校園，再到會議室，皆能無縫融入。數十年來，馬球衫歷經多次獨特的革新，展現出其持久的適應性；這種不斷演進的能力，確保了馬球衫歷久不衰的流行地位與文化意義。作為美國馬球協會（USPA）的官方運動品牌，U.S. Polo Assn. 佔據了馬球衫歷史中獨一無二的地位。USPA 成立於 1890 年，是美國歷史最悠久的體育管理機構之一。「馬球衫的基因深深植根於那項啟發它的鼓舞人心運動，」USPA Global 總裁兼執行長 J. Michael Prince 表示。該公司負責管理並推廣這個價值數十億美元的全球性 U.S. Polo Assn. 品牌。「透過『源自賽場的傳奇』系列，我們致敬這份始於球場的傳承，它持續塑造著全球馬球選手、運動迷及消費者當下的生活、行動與自我表達方式，並將影響未來的世代。」「源自賽場的傳奇」系列透過連結馬球衫與這項運動的淵源，同時彰顯其在現代文化中的地位，進而鞏固這份傳承。「這件馬球衫是專為比賽設計，在球場上確實有其實際用途，但它也是我場下外出用餐或與親友聚會時會穿的服裝，」U.S. Polo Assn. 全球品牌大使、6級美國職業馬球選手尼科·埃斯科巴（Nico Escobar）表示。「我很欣賞 U.S. Polo Assn. 既重視機能表現，也懂得如何讓馬球衫融入日常生活。」「U.S. Polo Assn. 與這項運動的真摯連結，以及它對全球馬球運動的支持，正是我無論在場上或場下都選擇穿著它的原因，」埃斯科巴補充道。全球發佈：「源自賽場的經典」「源自賽場的經典」系列將於2026年春季在全球190個國家同步上市，透過協調一致的多渠道佈局，讓美國馬球協會的馬球衫在消費者接觸這個運動靈感品牌的任何場合都清晰可見。在實體店鋪中，專門的馬球衫展示區——包括品牌標誌性的馬球衫牆、櫥窗陳列及視覺 merchandising 亮點——將透過大膽的色彩故事、清晰的品類劃分，以及以標語為核心的活動標識，全面呈現各類款式。無論是戶外廣告還是平面廣告，現場拍攝的主視覺影像將馬球衫帶回球場，強化其與這項運動的真實連結；而數位與社群媒體的推廣活動，則透過短片內容與全球敘事延展這個故事。這些接觸點共同營造出連貫且沉浸式的呈現，彰顯馬球衫作為真正標誌性單品的特質——它植根於運動，卻也與日常生活息息相關。此外，「源自賽場的經典」活動將配合美國兩項最重要的馬球賽事同步推出——包括享有盛譽的 USPA 金盃®（USPA Gold Cup®），以及全球競爭最激烈的賽事之一「美國公開馬球錦標賽®」（U.S. Open Polo Championship®），該賽事將於 4 月 26 日舉行冠軍決賽。「『源自賽場的經典』旨在擁抱我們的真實本質，並在國際舞台上大膽傳遞這份精神，」全球品牌行銷副總裁史蒂芬妮·科羅亞萊斯（Stefanie Coroalles）表示。「這場全球馬球衫宣傳活動融合了品牌傳承、產品特色與自我表達，展現了馬球衫如何從運動場域無縫融入日常生活。」「此次發布對我們而言是值得驕傲的時刻，它以現代、鮮明且無可辯駁的 U.S. Polo Assn. 風格，將我們的傳承賦予新生，」科羅亞萊斯補充道。產品核心理念：隨心所欲，盡情展現「每一件 U.S. Polo Assn. 馬球衫皆經過精心設計，在風格、舒適度、功能性與純正運動細節之間取得完美平衡，」品牌與產品開發資深副總裁布萊恩·卡米納（Brian Kaminer）表示。「從汲取傳統靈感的剪裁到現代機能面料，我們的 U.S. Polo Assn. 系列展現了馬球衫如何在忠於運動本源的同時，持續演進。」這場全球馬球衫宣傳活動透過五種獨特風格，展現這款經典單品的百變魅力，讓消費者在搭配馬球衫時，能盡情「隨心所欲，盡情展現」。「運動風」系列（Play It Sporty）的每一針每一線都承載著 U.S. Polo Assn. 的傳承。憑藉純正的細節、標誌性的品牌標識以及受運動啟發的元素，這款永恆的剪裁直接連結了品牌起源的馬球運動。官方徽章、經典剪裁與傳統設計細節，共同致敬馬球運動的歷史與品牌深厚的傳承。「Play It Classic」系列專為日常生活的點滴時刻而生。簡約、舒適且易於搭配，是您尋求百搭之選時的首選。這款專為反覆穿著而設計的 polo 衫，無論是休閒、放鬆或稍作打扮的場合，都能完美融入您的日常。「Play It in Motion」系列，專為動態活動打造的高性能POLO衫。採用先進技術面料，具備吸濕排汗的舒適感、透氣性及彈性，全天候隨您的動作靈活伸展。無論是球場上的POLO球員，還是追求動態生活的您，這款設計皆能兼顧耐用性與功能性，同時展現俐落現代的風格。「Play It Bold」系列，是專為自我表達而生的時尚POLO衫。這款作品以自信與風格為核心，為這款經典單品注入個性與自由。無論是隨性穿著或精心搭配，它都展現了當Polo衫由自信塑造、並依個人風格穿出時，其多變的魅力。「Play It Elevated」是為講究精緻的時刻打造的頂級Polo衫。採用高級面料與細膩工藝，呈現出精緻外觀卻不顯拘謹。簡潔的線條與貼合的剪裁，營造出沉穩而自信的風格，完美平衡了舒適與優雅。U.S. Polo Assn. 的季節性馬球衫涵蓋男裝、女裝及童裝系列，提供豐富多樣的面料、質感與色彩選擇——從經典中性色到鮮豔色調一應俱全。全新設計採用立體羅紋、低調圖案及精緻的工藝細節，並飾以品牌標誌性的「雙騎士」標誌——這不僅是正品的保證，更是這項運動的象徵。U.S. Polo Assn. 持續推出符合其全球永續發展計畫「USPA Life」的產品，體現品牌對負責任採購及長期環保倡議的承諾。將於 2027 年春季上市的 USPA Life 馬球衫，以 U.S. Polo Assn. 最具標誌性的款式為基礎，採用經過深思熟慮挑選的優質面料，彰顯品牌致力於改善這款經典單品對全球環境影響的決心。從 100% 優質棉面料到鈕扣與縫線等細節處理，每個環節皆經過精心挑選，在降低環境影響的同時，仍完整保留顧客對 U.S. Polo Assn. 馬球衫所期待的經典外觀、舒適度與品質。U.S. Polo Assn. 的服飾與配件現已於 U.S. Polo Assn. 實體門市及官網 uspoloassnglobal.com 販售。關於 U.S. Polo Assn. 與 USPA GlobalU.S. Polo Assn. 是美國馬球協會（USPA）的官方運動品牌。USPA 成立於 1890 年，是美國規模最大的馬球俱樂部與馬球選手組織。憑藉數十億美元的全球業務規模，以及透過超過 1,200 家 U.S. Polo Assn. 零售店和數千個其他銷售據點的全球分銷網絡，U.S. Polo Assn. 在全球 190 多個國家為男女及兒童提供服飾、配件和鞋類產品。該品牌贊助全球各大馬球賽事，包括每年於棕櫚灘的 NPC 舉辦的「美國公開馬球錦標賽®」（U.S. Open Polo Championship®），此為美國首屈一指的馬球錦標賽。透過與美國 ESPN、歐洲 TNT 和 Eurosport 以及印度 Star Sports 簽訂的歷史性合作協議，由 U.S. Polo Assn. 贊助的多項世界頂級馬球錦標賽現已透過電視轉播，讓全球數百萬體育迷首次得以欣賞這項令人熱血沸騰的運動。根據《License Global》的報導，U.S. Polo Assn. 一直與 NFL、PGA 巡迴賽及一級方程式賽車並列為全球頂尖的運動授權商之一。此外，這個以運動為靈感的品牌更因全球業務成長及運動內容而獲得國際獎項肯定。憑藉其作為全球品牌的巨大成功，U.S. Polo Assn. 曾獲《富比世》、《財星》、《現代零售》及《GQ》等媒體報導，並登上雅虎財經與彭博社等全球眾多知名媒體平台。欲了解更多資訊，請造訪 uspoloassnglobal.com 並追蹤 @uspoloassn。USPA Global 是美國馬球協會（USPA）的子公司，負責管理市值數十億美元的運動品牌 U.S. Polo Assn.。USPA Global 同時管理其子公司 Global Polo，該公司是全球馬球運動內容的領導者。欲了解更多資訊，請造訪 globalpolo.com 或 YouTube 上的 Global Polo 頻道。如需更多資訊，請聯絡：Stacey Kovalsky - 全球公關與傳播副總裁電話 +954.673.1331 - 電子郵件：skovalsky@uspagl.com 凱拉·德雷克（Kaela Drake） - 資深公關與傳播專員電話 +561.530.5300 - 電子郵件：kdrake@uspagl.com 消息來源：U.S. Polo Assn. Copyright 2026 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com

West Palm Beach, FL, Mar 26, 2026 - (ACN Newswire via SeaPRwire.com) - U.S. Polo Assn., the official sports brand of the United States Polo Association (USPA) founded in 1890, today announced the launch of its Global Polo Shirt Campaign, An Icon Born from the Game. The global campaign is a powerful tribute to the iconic polo shirt's authentic sports origins and its evolution into one of the world's most enduring style essentials.U.S. Polo Assn. Global Brand Ambassador, 6-goal American professional polo player Nico Escobar takes in the game atop his equine partner, wearing polo whites and a classic navy U.S. Polo Assn. polo shirt, An Icon Born from the GameU.S. Polo Assn. models in polo shirts at the Spring-Summer 2026 Global Collection Photoshoot in Charleston, South Carolina‘The Polo Shirt: An Icon Born From the Game' campaign imagery featuring U.S. Polo Assn. modelsThe polo shirt's beginning was born on the polo fields, shaped by motion, competition, and the spirit of the game for which it was named. From its earliest days, the polo shirt was designed with purpose, worn by players seeking performance on the polo fields. Today, U.S. Polo Assn. celebrates this timeless favorite, not just as a fashion item, but as an icon born from sport and carried forward through generations of players and consumers all over the world.The polo shirt is one of the most iconic essentials dating back over 100 years, notable for its unique fusion of sport and style. Originally designed with breathable pique knit, a soft collar, and lightweight construction to meet the demands of competitive sports, it has evolved into a timeless essential, suitable for casual elegance and leisurewear.The polo shirt traces its origins to polo players, where it was created out of necessity for the sport. Polo players modified long‑sleeved cotton shirts to better handle heat, movement, and wind while playing. These functional, sport‑driven adaptations represent the earliest form of what would become the polo shirt. In the early 20th century, polo players helped formalize these functional elements as the sport gained popularity, reinforcing the shirt's connection to the sport and its functional design.Over the years, the polo shirt became a cornerstone of casual sportswear around the world, symbolizing preppy style, luxury leisure culture, and contemporary athleisure, seamlessly transitioning from polo fields to college campuses and boardrooms. Its enduring adaptability is demonstrated by distinct reinventions across the decades; the ability to evolve has ensured the polo shirt's lasting relevance and cultural significance.As the official sports brand of the USPA, founded in 1890 and one of the oldest sports governing bodies in the United States, U.S. Polo Assn. occupies an authentic place in the history of the polo shirt."The polo shirt's DNA is deeply rooted in the inspirational sport that inspired it," said J. Michael Prince, President and CEO of USPA Global, the company that manages and markets the multi-billion-dollar, global U.S. Polo Assn. brand. "With An Icon Born from the Game, we're honoring a legacy that began on the field and continues to shape how polo players, sports fans, and consumers all over the world live, move, and express themselves today, and for future generations."An Icon Born from the Game reinforces that legacy by connecting the polo shirt's origins in the sport, while celebrating its place in modern culture."The polo shirt was designed for the game with a real purpose on the field, but it's also what I wear off the field to go out to dinner or hang out with friends and family," said Nico Escobar, U.S. Polo Assn. Global Brand Ambassador, 6-goal American professional polo player. "I love that U.S. Polo Assn. understands both the performance aspect and how the polo shirt fits into everyday life.""U.S. Polo Assn.'s authentic connection to the sport and the way it supports the game of polo around the world is why I wear it - both on the field and off," adds Escobar.Global Launch: An Icon Born from the GameLaunching globally across 190 countries in Spring 2026, An Icon Born from the Game will come to life through a coordinated, multi‑channel presence designed to make the U.S. Polo Assn. polo shirt unmistakably visible wherever consumers engage with the sport-inspired brand. In stores, dedicated polo shirt focus areas, including the brand's iconic polo walls, window displays, and visual merchandising moments, will highlight the full range of styles through bold color stories, clear categorization, and campaign signage anchored by the slogan.Across outdoor and print advertising, hero imagery shot on location brings the polo shirt back to the field, reinforcing its authentic connection to the sport, while digital and social media activations extend the story through short‑form content and global storytelling. Together, these touchpoints create a consistent, immersive expression of the polo shirt as a true icon rooted in sport but relevant to everyday life.Further, An Icon Born from the Game is launching around two of the sport's most important events in the United States - the prestigious USPA Gold Cup® and one of the most competitive tournaments in the world, the U.S. Open Polo Championship®, which concludes with the Championship Final on April 26."An Icon Born from the Game is about owning our truth and telling it boldly on a global scale," said Stefanie Coroalles, Vice President, Global Brand Marketing. "The Global Polo Shirt Campaign brings together heritage, product, and self-expression, showing how the polo shirt moves effortlessly from sport to everyday life.""This launch is a proud moment for us, one that brings our heritage to life in a way that feels modern, visible, and unmistakably U.S. Polo Assn.," adds Coroalles.Product Pillars: Play It Your Way"Every U.S. Polo Assn. polo shirt is designed with intention by balancing style, comfort, function, and authentic sport details," said Brian Kaminer, Senior Vice President, Brand and Product Development. "From heritage-inspired construction to modern performance fabrics, our U.S. Polo Assn. collections reflect how the polo shirt continues to evolve while staying true to its sports roots."The global polo shirt campaign showcases the versatility of the icon through five distinct expressions that give the consumer the opportunity to "Play It Your Way" when styling with the polo shirt.Play It Sporty is the polo shirt that carries the legacy of U.S. Polo Assn. in every stitch. Featuring authentic detailing, iconic branding, and sport-inspired elements, this timeless silhouette connects directly to the game that started it all. Official crests, classic cuts, and traditional design details celebrate the sport of polo's history and the brand's deep-rooted heritage.Play It Classic is the polo shirt for the moments that make up everyday life. Clean, comfortable, and easy to style, it's the go-to option when you want something that always works. Designed to be worn again and again, it fits seamlessly into any routine, whether casual, relaxed, or slightly dressed up.Play It in Motion with the performance polo shirt engineered for action. Advanced technical fabrics deliver moisture-wicking comfort, breathability, and stretch that moves with you throughout the day. Designed for polo players on the field or in life in motion, it balances durability and function with a sharp, modern look.Play It Bold is the fashion polo shirt built for self-expression. Defined by confidence and style, this version brings personality and freedom to a familiar icon. Worn casually or styled with intention, it shows how versatile the polo shirt can be when it's shaped by confidence and worn on an individual's own terms.Play It Elevated is the premium polo shirt made for moments that call for refinement. Crafted with elevated materials and thoughtful detailing, it offers a polished look without feeling formal. Clean lines and a thoughtful fit create a composed yet confident style that balances ease with sophistication.U.S. Polo Assn.'s seasonal polo shirts are offered across men's, women's, and kids' collections in an expansive range of fabrics, finishes, and colors - from classic neutrals to vibrant hues. Updated designs feature textured ribs, subtle patterns, and elevated construction details, finished with the brand's signature Double Horsemen logo - a mark of authenticity and a symbol of the sport.U.S. Polo Assn. continues to incorporate products aligned with its global sustainability program, USPA Life, reflecting the brand's commitment to responsible sourcing and long-term environmental initiatives. The USPA Life Polo Shirt, arriving in stores Spring 2027, builds on U.S. Polo Assn.'s most iconic style, designed with thoughtfully chosen, preferred materials that reflect the brand's commitment to improving the global footprint of this iconic staple. From 100% preferred cotton fabric to the finishing details like buttons and thread, each element has been selected to reduce impact while preserving the classic look, comfort, and quality customers expect from a U.S. Polo Assn. polo shirt.U.S. Polo Assn. apparel and accessories are available in U.S. Polo Assn. stores and online at uspoloassnglobal.com.About U.S. Polo Assn. and USPA GlobalU.S. Polo Assn. is the official sports brand of the United States Polo Association (USPA), the largest association of polo clubs and polo players in the United States, founded in 1890. With a multi-billion-dollar global footprint and worldwide distribution through more than 1,200 U.S. Polo Assn. retail stores as well as thousands of additional points of distribution, U.S. Polo Assn. offers apparel, accessories, and footwear for men, women, and children in more than 190 countries worldwide. The brand sponsors major polo events around the world, including the U.S. Open Polo Championship®, held annually at NPC in The Palm Beaches, the premier polo tournament in the United States. Historic deals with ESPN in the United States, TNT and Eurosport in Europe, and Star Sportsin India now broadcast several of the premier polo championships in the world, sponsored by U.S. Polo Assn., making the thrilling sport accessible to millions of sports fans globally for the very first time.U.S. Polo Assn. has consistently been named one of the top global sports licensors in the world alongside the NFL, PGA Tour, and Formula 1, according to License Global. In addition, the sport-inspired brand is being recognized internationally with awards for global growth and sports content. Due to its tremendous success as a global brand, U.S. Polo Assn. has been featured in Forbes, Fortune, Modern Retail, and GQ as well as on Yahoo Finance and Bloomberg, among many other noteworthy media sources around the world. For more information, visit uspoloassnglobal.com and follow @uspoloassn.USPA Global is a subsidiary of the United States Polo Association (USPA) and manages the multi-billion-dollar sports brand, U.S. Polo Assn. USPA Global also manages the subsidiary, Global Polo, which is the worldwide leader in polo sport content. To learn more, visit globalpolo.com or Global Polo on YouTube.For Additional Information, Contact:Stacey Kovalsky - VP, Global PR and CommunicationsPhone +954.673.1331 - E-mail: skovalsky@uspagl.comKaela Drake - Senior PR and Comms SpecialistPhone +561.530.5300 - E-mail: kdrake@uspagl.comSOURCE: U.S. Polo Assn. Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com

香港, 2026年3月26日 - (亞太商訊 via SeaPRwire.com) - 聚焦於腫瘤治療領域的創新型生物製藥公司──樂普生物科技股份有限公司(「樂普生物」或「公司」，股份代號：2157.HK)公佈2025年全年業績。報告期內，公司業務及收入現強勁增長，首年實現盈利，全球首創EGFR靶向ADC美佑恆®獲批上市，核心產品商業化提速，多項國際授權合作順利推進。於報告期內，樂普生物收入實現顯著增加，總收入約為人民幣934.9百萬元，約為2024年收入的2.5倍。其中在國內商業化方面，普佑恆®（普特利單抗注射液）及美佑恒®（注射用維貝柯妥塔單抗）的收入約人民幣501.0百萬元，同比大幅增加66.8%；在許可業務方面，實現收入約人民幣424.2 百萬元，主要來自MRG007及TCE資產的對外授權。同時，公司首年實現盈利約人民幣261.4百萬元，較2024年大幅增加。經營現金流量持續向好，現金及現金等價物約為人民幣8.53億元，為2024年的兩倍以上。研發開支約人民幣4億元，較2024年同期下降8.5%，在保障核心管線推進的同時，成本控制成效顯現。核心產品商業化提速 兩項國際授權合作順利落地作為一家立足中國、面向全球的聚焦於腫瘤治療領域（尤其是靶向治療及免疫治療）的創新型生物製藥企業，樂普生物致力於通過全面且先進的ADC技術開發平台開發創新型ADC，並旨在開發出優化、創新的藥物，更好地填補癌症患者的臨床需求缺口。公司致力於通過充分整合自主創新能力及戰略合作，持續開發市場差異化產品管線。隨着ADC候選藥物進入商業化階段，公司已建立並正在逐步擴大內部生產能力以滿足業務發展的需求。目前，樂普生物已戰略性佈局了多個腫瘤產品管線。截至公告日期，公司擁有(i)兩種臨床/商業化階段候選藥物；(ii)八種臨床階段候選藥物，包括一種透過合營企業共同開發的藥物；及(iii)五種候選藥物的臨床階段聯合療法。公司有兩種候選藥物已就其靶向適應症獲得上市批准，其他適應症的臨床試驗正在進行中。在八種臨床階段候選藥物中，六種為靶向療法藥物，兩種為免疫治療藥物（分別為一種溶瘤病毒藥物及T細胞激動性抗體）。截至報告期末，通過國內商業化及業務開發活動，樂普生物在研發能力變現方面取得重要里程碑。普佑恆®（普特利單抗注射液）已完成商業化全流程，目前正處於銷售快速增長階段。憑藉這一勢頭，公司旨在優化美佑恆®（注射用維貝柯妥塔單抗）(FIC EGFR-ADC)的商業化策略，以推動更有效的市場滲透及增長。此外，另有兩款產品CMG901及MRG007也通過業務開發活動成功達成授權合作。CMG901的全球權益已授權予AstraZeneca，MRG007的大中華區以外地區權益已授權予ArriVent。多管線产品進入關鍵階段 創新ADC潛力釋放於2025年，樂普生物的全球首創EGFR靶向ADC美佑恆®已在中國獲得上市批准。同時，我們有更多候選藥物進入關鍵臨床階段，且通過開發及優化聯合治療方案實現了治療線數前移。CMG901(CLDN 18.2-ADC)：AstraZeneca於2023年2平台月獲授CMG901 (AZD0901)的研究、開發、註冊、生產及商業化獨家全球許可。AstraZeneca正積極進行CMG901的兩項III期臨床試驗：一項作為晚期/ 轉移性胃或胃食管連接部腺癌的單一療法，另一項作為與卡培他濱（伴有或不伴有rilvegostomig）聯合治療CLDN 18.2陽性和HER2陰性晚期/轉移性胃、胃食管連接部或食管腺癌的一線治療。根據許可協議，聯合試驗中首名患者的給藥已觸發45百萬美元的里程碑付款，該付款由AstraZeneca支付。MRG004A (TF-ADC)：目前正在中國進行治療PDAC的III期臨床試驗。於2025年8月，MRG004A獲國家藥監局CDE授予BTD。PC的Ib期擴展階段良好數據已於2025年ESMO大會上呈現。CG0070（溶瘤病毒）：目前公司的美國合作夥伴CG Oncology正進行CG0070的MRCT III期臨床研究。觀察到的最新良好數據已於第26屆SUO年會上作為LBA以口頭匯報形式呈現。截至2025年12月31日，公司已啟動國內關鍵臨床試驗的患者入組。此外，CG0070於2025年獲國家藥監局CDE授予BTD。MRG001 (CD20-ADC)：公司正在進行一項II期臨床研究，以評估MRG001聯合BTK抑制劑治療DLBCL患者的療效，該研究的良好中期數據已於第67屆ASH年會上呈現。MRG006A (GPC3-ADC)：MRG006A是一款基於新型拓撲異構酶I抑制劑且具有全球FIC潛力的GPC-3靶向ADC候選產品，乃基於Hi-TOPi ADC平台開發。目前正在中國進行HCC的II期臨床試驗。此外，公司獲得FDA的MRG006A IND核准，且該藥物獲FDA授予FTD及ODD認定。I期臨床研究的良好數據已讀出，並計劃於2026年ASCO大會上呈現。MRG007 (CDH17-ADC)：公司與ArriVent正於中國及美國同步進行一項針對不可切除的局部晚期或轉移性實體瘤治療的I期MRCT。於2025年AACR年會上呈現的MRG007的臨床前數據顯示出治療消化道癌的良好臨床潛力。於2025 年1 月，公司與Ar riVent訂立獨家許可協議，據此，公司授予ArriVent在大中華區以外地區開發、製造及商業化MRG007的獨家權利。根據協議條款，公司有資格獲得總計最高達12億美元的首付款及開發、監管及銷售里程碑付款，連同銷售淨額的分級特許權使用費。聯合療法布局：截至2025年12月31日，公司正在進行HNSCC的隨機、開放、多中心III期臨床研究。在美佑恆®與普特利單抗聯合治療方面，公司目前正在進行HNSCC的II期臨床試驗（該試驗已提線至一線治療），其II期臨床試驗的良好數據已於2025年ESMO大會上呈現。公司亦正在歐洲進行針對LA-HNSCC的II期臨床試驗。此外，公司獲得國家藥監局CDE關於在中國開展美佑恆®與普特利單抗聯合療法的IND批准，旨在評估該方案在手術干預前對術前LA-HNSCC患者的療效及安全性。創新平台：公司不斷努力建立和開發新的技術平台，作為公司的創新引擎，同時推動新型創新分子管線的持續進展。公司的研發平台—Hi-TOPi ADC平台及T細胞銜接器平台已成熟並經過驗證。除管線中的在研產品外，公司亦正通過自有研發平台積極開發多特異性抗體IO及多特異性抗體ADC候選藥物。公司計劃於2026年4月的AACR年會上呈現一款雙特異性ADC候選藥物及一款新型免疫腫瘤融合蛋白候選產品的臨床前數據。未來展望：加快後期產品的商業化 加大全球市場拓展力度在藥物研發方面，公司將進一步聚焦於推動下一代ADC藥物及免疫腫瘤雙╱ 三特異性抗體的戰略研發，同時加快後期產品的商業化。此外，公司的核心候選藥物正進入關鍵臨床階段。MRG004A目前正在進行III期臨床試驗的患者入組。CG0070已啟動國內關鍵臨床試驗的患者入組。公司亦將加快推進包括MRG006A及MRG007在內的其他創新候選藥物進入關鍵臨床階段。同時，我們正在不斷探索管線內聯合療法的潛在療效，努力為更廣泛的患者群體帶來更大的臨床效益。在國內商業化方面，公司將繼續集中資源及努力推動商業化進程，專注於提高獲批產品的市場佔有率及銷售表現。公司將採取進一步措施提高這兩款產品的市場可及性，加快各級市場滲透，進一步擴大市場份額。憑藉商業化團隊的專業知識及行業資源，公司將尋求通過市場營銷、學術推廣等各種方式提升品牌形象及市場認知度。同時，公司將根據美佑恆®（注射用維貝柯妥塔單抗）的實際銷售表現優化商業化策略，並利用已全面擴大的營銷及商業化團隊，專注於推動總收入增長。在國際方面，公司將加大在全球市場的拓展力度，堅持不懈地擴大國際網絡，並探索新的業務開發合作機會。公司將繼續致力於在全球範圍內尋找更多戰略合作夥伴，通過合作、授權協議或合營企業等方式開發ADC產品和其他創新候選藥物。 Copyright 2026 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com