巨生醫細胞治療新藥MPB-2354於世界分子影像學會發表

EQS 新聞 via SEAPRWire.com / 2024-10-23 / 11:34 UTC+8 奈米藥物開發新藥公司-巨生生醫股份有限公司(以下簡稱”巨生醫”,台灣櫃買中心股票代碼:6827)今日宣布,將由研發副總許源宏博士於2024年10月6日至9日,代表巨生醫前赴挪威奧斯陸參加世界分子影像學會(World Molecular Imaging Society, WMIS) 每兩年舉辦一次的顯影劑研究研討會 (Contrast Media Research Symposium 2024),並以口頭方式發表MPB-2354具優異抗發炎效果及活體影像追蹤雙功能的異體幹細胞製劑在細胞治療領域的研究成果。國際主要顯影劑研究單位及藥廠均與會參與WMIS,包含國際知名大廠GE、Bayer、Bracco及Guerbet等。巨生醫許源宏博士表示,MPB-2354為結合旗下自主研發的奈米微粒技術平台—氧化鐵奈米微粒(IOP)與異體脂肪幹細胞,發展成同時具有優異抗發炎效果及活體影像追蹤雙功能的異體幹細胞製劑。藉由新的創新結構,使MPB-2354具有下列優勢; IOP的MRI顯影能力及被幹細胞吞噬效率優於類似產品,目前在體外試驗及動物實驗驗證了MRI顯影追蹤能力,顯影效果更強且能持續顯影的時間更長。 較高的吞噬量,亦會改變幹細胞原有形態及功能,IOP也已有完整的前臨床及臨床安全性數據,未來MPB-2354進入人體臨床試驗的安全性疑慮低。 可強化細胞抗發炎能力,IOP中的氧化鐵成分具有調節細胞中與鐵相關代謝途徑的潛力,使其在被MSC吞噬後(IOP-ADSC)更能夠促使IDO1的活性能力提升,並藉此開啟MSC的免疫調節正回饋循環,加強其免疫抑制能力 巨生醫所研發的細胞治療產品MPB-2354,在研究中展現了顯影能力,在MRI T2*序列的照射下,都展現了植入細胞追蹤的功能,可以確保細胞治療的品質,監測注射後細胞的位置、存留狀態和活性等訊息將在制定臨床治療方案中發揮重要作用。同時,根據我們的的前臨床實驗結果,MPB-2354(IOP標記的ADSC)與單純的ADSC相比,在抗發炎反應效果上有顯著的提升。MPB-2354為同時具有優異抗發炎效果及活體影像追蹤雙功能的異體幹細胞製劑,具有目前同類型市售產品所沒有的優勢,擁有強大的潛力成為臨床替代治療方案的產品。 2024-10-23 此財經新聞稿由EQS Group via SEAPRWire.com轉載。本公告內容由發行人全權負責。瀏覽原文: http://www.todayir.com/tc/index.php
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Fujitsu to offer AI agents that can both collaborate and engage in high-level tasks autonomously JCN Newswire

Fujitsu to offer AI agents that can both collaborate and engage in high-level tasks autonomously

TOKYO, Oct 23, 2024 - (JCN Newswire via SeaPRwire.com) - Fujitsu today announced the global launch of its Fujitsu Kozuchi AI Agent, an AI service that can engage in high-level tasks both autonomously and in collaboration with humans. This service will be offered through Fujitsu Data Intelligence PaaS, Fujitsu’s all-in-one operation platform that is part of the Fujitsu Uvance business model which works to provide cross-industry solutions to societal issues. As of today, Fujitsu will offer the first AI agent, for use in business profitability discussions and business negotiations to share appropriate information and propose measures. Fujitsu plans to eventually expand its AI agent lineup to include services in production management and legal affairs, and other areas, and will implement a broader roll-out of the service during fiscal 2024. In addition, Fujitsu will incorporate Fujitsu Kozuchi AI Agent into its digital offerings, including Fujitsu Uvance’s Work Life Shift.Building generative AI models for business applications requires a significant investment of time and money as well as a high level of expertise and there is no guarantee that a single AI model can deliver the desired results.To solve this issue, Fujitsu has developed the Fujitsu Kozuchi AI Agent. This AI can think autonomously and function as a full team member, making proactive suggestions that can lead to new insights and inspire creativity.The Fujitsu Kozuchi AI Agent uses Fujitsu’s proprietary processing logic to break down abstract issues from conversations and generate discrete tasks. The agent creates a plan to complete the tasks and selects multiple optimal AIs to implement. Models available include those developed by Fujitsu, such as Takane, a large-scale language model for enterprises with the world’s best Japanese language capability and significant customization options, Fujitsu Kozuchi AutoML, which generates advanced machine learning models in a short amount of time, as well as various models from other companies. The Fujitsu Kozuchi AI Agent provides instructions to each of the AI models and provides a solution based on the feedback.For example, the AI agent for use in business meetings will autonomously participate in necessary meetings. To give an example situation, if one of the meeting participants were to state that sales revenue in the Asia Region was half of what it had been the previous year, the AI agent would select several AI and direct them to perform an analysis based on this statement. Then, as a result, the AI agent would autonomously present a clear answer, for example stating that “I will show the amount of sales revenue from April through September in the previous and current fiscal years as a bar graph. As shown in the graph, sales revenue in other regions is the same or slightly up from the previous fiscal year, and only sales revenue in the Asia Region is down. It has decreased by 54% compared to the previous fiscal year.” In this manner, Fujitsu Kozuchi AI Agent will support the smooth progression of meetings and will contribute to increased productivity.Fujitsu will promote the use of AI agents in a wide range of business operations to further improve the efficiency of customers' businesses, and work to achieve a world in which customers can easily benefit from business transformation via generative AI.About FujitsuFujitsu’s purpose is to make the world more sustainable by building trust in society through innovation. As the digital transformation partner of choice for customers in over 100 countries, our 124,000 employees work to resolve some of the greatest challenges facing humanity. Our range of services and solutions draw on five key technologies: Computing, Networks, AI, Data & Security, and Converging Technologies, which we bring together to deliver sustainability transformation. Fujitsu Limited (TSE:6702) reported consolidated revenues of 3.7 trillion yen (US$26 billion) for the fiscal year ended March 31, 2024 and remains the top digital services company in Japan by market share. Find out more: www.fujitsu.com.Press ContactsFujitsu LimitedPublic and Investor Relations DivisionInquiries Copyright 2024 JCN Newswire via SeaPRwire.com.
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T.MAN Pharmaceutical PCL (SET: TMAN) Showcases Leadership in Health Innovation, Aiming for Sustainable Growth Following Listing on SET ACN Newswire

T.MAN Pharmaceutical PCL (SET: TMAN) Showcases Leadership in Health Innovation, Aiming for Sustainable Growth Following Listing on SET

BANGKOK, Oct 22, 2024 - (ACN Newswire via SeaPRwire.com) - T.MAN Pharmaceutical PCL (SET: TMAN), a leader in the production and distribution of pharmaceuticals and healthcare products in Thailand for over 50 years, debuts on the Stock Exchange of Thailand (SET) under the Personal Products & Pharmaceuticals sector. The company has showcased its commitment to investing in technology to enhance production and efficiency, focusing on the research, development, and innovation of pharmaceuticals and healthcare products. Aiming to expand its market presence both domestically and internationally, the company strives to be a leader in health innovation that enhances the quality of life for all.Mr. Prapon Thanachotipan, Chief Executive Officer of T.MAN Pharmaceutical PCL ("the company" or "TMAN"), announces that the company starts trading its shares on the SET on October 22, 2024, under the consumer products industry group, specifically in the personal products and pharmaceuticals category, using the ticker symbol “TMAN”. He expresses confidence that the company’s strong foundation in health innovation, from research and development of pharmaceuticals and healthcare products to enhancing production standards with modern technology and effective marketing strategies, will make TMAN a quality stock that attracts investors. The company aims to be a leader in health innovation, helping to improve the quality of life for everyone.Following its listing, the company has allocated a short-to-medium-term investment budget not exceeding 777.5 million THB, divided as follows:1) Ongoing projects involving construction and machinery installation, totaling up to 298.5 million THB. These include:1.1) Projects to improve the efficiency of herbal product manufacturing,1.2) Projects to enhance the efficiency of modern medicine production,1.3) Expansion of research and development,1.4) Increased production capacity for dietary supplements,1.5) Development of sales systems using information technology,1.6) Procurement of quality control equipment for modern medicine,1.7) Procurement of quality control equipment for dietary supplements, and1.8) Construction of warehouses and office buildings, with several projects already underway.2) The company has also planned future investments for business expansion in 5 projects, with a budget not exceeding 479.0 million THB. These include:2.1) Construction of a new headquarters building,2.2) The first phase of expanding production capacity for modern medicine,2.3) Investment in the installation of solar panels (Solar Rooftop),2.4) Upgrading production areas for modern medicine, and2.5) The second phase of expanding production capacity for modern medicine.Mr. Prapon states that after being listed on the stock exchange, the company has strategized for sustainable growth by focusing on building brand recognition and acceptance for its products. It aims to develop pharmaceuticals for chronic non-communicable diseases (NCDs) and respiratory conditions to expand its customer base among hospitals, a major segment in the pharmaceutical industry. Currently, the company has over 226 brands. Additionally, it will continue to research and develop diverse and high-quality health innovations to fully meet customer needs. The company also plans to increase its contract manufacturing (OEM/ODM) and distribution services, while boosting revenue growth by expanding product distribution to over 22 countries worldwide, aiming to become a global brand in the future.Mr. Thinnaphan Wanglee, Deputy Managing Director of Kasikorn Securities Public Company Limited, acting as the financial advisor and lead underwriter, states that TMAN is a leading group in the production and distribution of pharmaceuticals and health products in Thailand. It is at the forefront of inventing, researching, and developing pharmaceuticals and healthcare products that fit current trends in preventive and therapeutic healthcare. TMAN has enhanced its R&D centers and production facilities with modern technology, improving its competitiveness as well as aggressively expanding its business both domestically and internationally, driven by strong business strategies that will enable sustainable growth.Analysts from leading securities firms view TMAN shares as having a solid foundation, with a diverse range of over 842 SKUs in pharmaceuticals and healthcare products, many of which are popular in the market with strong brand presence. The company plans to launch 10-12 new products annually, backed by research and development that swiftly addresses consumer needs. Strategies to expand its customer base among hospitals and penetrate international markets are expected to drive continuous sales growth both domestically and abroad. Effective cost management through direct distribution to customers also contributes to its growth. Analysts have assessed the fundamental value of TMAN shares to be in the range of 24.0-29.5 THB per share, with a positive outlook driven by the following factors: 1) Expanding product lines under existing brands, 2) Launching new products under the TMAN brand, 3) Expanding the customer base among hospitals, 4) Continuously growing distribution channels, and 5) Boosting international sales to move towards becoming a global brand.Additionally, TMAN engages in third-party distribution, which provides in-depth market and consumer behavior insights that support the company's growth. The current consumer trend toward health consciousness, which is a global megatrend, further drives this growth.Released by Public Relations Dept, MT Multimedia Co., Ltd for T.MAN Pharmaceutical PCL or TMANFor more information, please contact: Pipop (Top)Tel. +66 81-929-8864; Email: pipop.k@mtmultimedia.com T.MAN Pharmaceutical PCL [SET: TMAN; TMAN/F; TMAN-R] https://www.tmanpharma.in.th/en/home-en/ Copyright 2024 ACN Newswire via SeaPRwire.com.
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BlackBerry Partners with ISC2 to Advance Cybersecurity Skills in Malaysia ACN Newswire

BlackBerry Partners with ISC2 to Advance Cybersecurity Skills in Malaysia

KUALA LUMPUR, Oct 23, 2024 - (ACN Newswire via SeaPRwire.com) - BlackBerry Limited (NYSE:BB)(TSX:BB) has announced a new partnership with The International Information System Security Certification Consortium (ISC2), the world's leading nonprofit member organization for cybersecurity professionals, to deliver its globally recognized cybersecurity training and certifications in Malaysia. In support of the Malaysian Government's ongoing efforts to boost digital skills, capacity and cyber-resilience, the courses are now offered as part of the BlackBerry Cybersecurity Curriculum at the world-class Cybersecurity Center of Excellence (CCoE) facility in Cyberjaya. Registration is now open for the first ISC2 courses taking place later this month.As Malaysia's digital transformation continues to accelerate and threat surfaces expand, so too does the demand for highly-qualified cybersecurity professionals. BlackBerry's new partnership with ISC2 extends the range of internationally-certified courses available to cyber professionals at the Malaysia CCoE to help upskill and enhance capabilities to bolster defenses against ever-evolving cyber threats. The courses include ISC2's highly sought-after Certified Information Systems Security Professionals (CISSP), Certified Cloud Security Professional (CCSP) and Certified in Cybersecurity (CC).Han Ther Lee, Director of Education and Training, Cybersecurity Center of Excellence, BlackBerry, commented, "As Malaysia prepares for the ‘Year of Skills' in 2025, BlackBerry remains committed to collaborating with government and industry to help educate, upskill and grow the nation's cyber-workforce. We are proud to partner with another top-tier training institution like ISC2, further enriching the curriculum offered at the Cybersecurity Center of Excellence and giving cyber professionals in Malaysia and the region wider access to globally recognized certifications."The first courses offered through the partnership will focus on critical cybersecurity disciplines, including security operations, risk management, and cloud security, vital to strengthening national and regional cybersecurity capabilities, especially as the region pushes forward its digital transformation goals. ISC2 will provide comprehensive training materials, course resources, licenses, and ongoing support for all its programs.Cigdem Bildirici​​​​, Vice President, Business Development, ISC2 added, "With Malaysia advancing towards a more digitally connected future and the accompanying rise in cyber risks, strengthening the cybersecurity workforce has become more vital than ever. We're excited to collaborate with BlackBerry at the Cybersecurity Center of Excellence to bring our training programs to support this growth."Since opening the CCoE in March 2024, with the support of the Malaysian Communications and Multimedia Commission (MCMC), BlackBerry and its education partners have dedicated over 8,000 hours to train over 1,500 professionals at the facility. Several education partnerships also offer globally-certified training courses at the CCoE, including CompTIA, SANS Institute and the Rogers Cybersecure Catalyst ("the Catalyst") at Toronto Metropolitan University, which runs its CLIC (Certifications of Leadership in Cybersecurity) training program.Now in its sixth month of operations, the addition of ISC2 training programs at the CCoE is another milestone achievement for the non-profit institution, which aims to provide the most comprehensive set of certifications and training courses available in the Indo-Pacific region.The first wave of ISC2 certification courses, Certified in Cybersecurity (CC) will commence by the end of October 2024, while the renowned CISSP and CCSP programs, will start in November 2024. Cybersecurity professionals and organizations across Malaysia and the Indo-Pacific region can now register for the ISC2 courses here. Additional programs, such as specialized workshops and advanced training, will be rolled out in the months to follow, providing continuous opportunities for upskilling and certification.About ISC2ISC2 is the world's leading member organization for cybersecurity professionals, driven by our vision of a safe and secure cyber world. Our nearly 675,000 members, candidates and associates around the globe are a force for good, safeguarding the way we live. Our award-winning certifications - including cybersecurity's premier certification, the CISSP® - enable professionals to demonstrate their knowledge, skills and abilities at every stage of their careers. ISC2 strengthens the influence, diversity and vitality of the cybersecurity profession through advocacy, expertise and workforce empowerment that accelerates cyber safety and security in an interconnected world. Our charitable foundation, The Center for Cyber Safety and Education, helps create more access to cyber careers and educate those most vulnerable. Learn more and get involved at ISC2.org. Connect with us on X, Facebook and LinkedIn.© 2024 ISC2 Inc., ISC2, CISSP, SSCP, CCSP, CGRC, CSSLP, HCISPP, ISSAP, ISSEP, ISSMP, CC, and CBK are registered marks of ISC2, Inc.About BlackBerryBlackBerry (NYSE:BB)(TSX:BB) provides intelligent security software and services to enterprises and governments around the world. The company's software powers over 235M vehicles. Based in Waterloo, Ontario, the company leverages AI and machine learning to deliver innovative solutions in the areas of cybersecurity, safety and data privacy, and is a leader in the areas of endpoint security management, encryption, and embedded systems. BlackBerry's vision is clear - to secure a connected future you can trust.BlackBerry. Intelligent Security. Everywhere.For more information, visit BlackBerry.com and follow @BlackBerry.Media Contact:BlackBerry Media Relations+1 (519) 597-7273mediarelations@blackBerry.comSOURCE: BlackBerry Copyright 2024 ACN Newswire via SeaPRwire.com.
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歐盟議員稱凍結俄羅斯資產是「盜竊」

(SeaPRwire) - 斯洛伐克歐洲議会議員 Lubos Blaha 質疑了對莫斯科的行動,指出美國在攻擊伊拉克時,其資金並沒有成為目標。 斯洛伐克歐洲議会議員 Lubos Blaha 表示,西方凍結俄羅斯主權基金等同於“盜竊”。他呼籲歐盟當局停止向烏克蘭輸送資金和武器,以應對與莫斯科的衝突。 自烏克蘭衝突在兩年前加劇以來,美國、歐盟及其盟友已凍結了約 3000 億美元的俄羅斯國家資產。大部分資金,約 1970 億歐元(2140 億美元),由位於布魯塞爾的結算所 Euroclear 持有。 “凍結俄羅斯資產是盜竊和搶劫。你可以找到數百種為此辯護的理由,但這就是盜竊,” Blaha 在週一斯特拉斯堡的歐洲議會全體會議上說。 “歐洲在對伊拉克發動無端的侵略時沒有偷竊美國的資產,我們會對以色列的資產做同樣的事情嗎?”這位議員問道,指的是最近以巴衝突的升級。 Blaha 本月早些時候訪問了莫斯科,他還呼籲歐盟議員使用“常識”,表示布魯塞爾應該“停止向烏克蘭運送武器和數十億歐元”,這些資金是歐盟所需要的。 “這對我們自己的公民來說是不公平的,”這位歐洲議会議員堅持說。 週二,歐洲議會支持向烏克蘭提供高達 350 億歐元(380 億美元)的貸款,使用被凍結的俄羅斯資產作為償還債務的抵押品。據 Euroclear 稱,截至 7 月中旬,被凍結的資金已產生 34 億歐元(37 億美元)的利息。 根據 Blaha 的說法,“停止烏克蘭的苦難的唯一方法是結束北約的擴張”,他譴責歐洲議會中日益增長的恐俄症和“軍事主義和仇恨言論”。 斯洛伐克歐洲議会議員 Milan Uhrik 呼應了他的觀點,他抨擊了對烏克蘭的進一步財務援助。 “他們取消了選舉,他們鎮壓了反對派,他們取消了少數民族和獨立媒體的權利,然而你卻想給他們送更多的錢,”Uhrik 說。本文由第三方廠商內容提供者提供。SeaPRwire (https://www.seaprwire.com/)對此不作任何保證或陳述。 分類: 頭條新聞,日常新聞 SeaPRwire為公司和機構提供全球新聞稿發佈,覆蓋超過6,500個媒體庫、86,000名編輯和記者,以及350萬以上終端桌面和手機App。SeaPRwire支持英、日、德、韓、法、俄、印尼、馬來、越南、中文等多種語言新聞稿發佈。
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ONERHT Foundation Celebrates 9th Charity Golf and Gala Dinner Event, Raising Over S$430,000 to Support 9 Charitable Organisations ACN Newswire

ONERHT Foundation Celebrates 9th Charity Golf and Gala Dinner Event, Raising Over S$430,000 to Support 9 Charitable Organisations

SINGAPORE, Oct 22, 2024 - (ACN Newswire via SeaPRwire.com) - ONERHT Foundation Ltd, the corporate social responsibility arm of RHTLaw Asia LLP and the RHT Group of Companies (“ONERHT”), successfully raised more than S$430,000 at its 9th charity golf and gala dinner event. The funds will be directed towards the Foundation’s key initiatives, including the Ageing RigHT Project and other community programmes aimed at supporting Singapore’s ageing population and diverse community needs.Ms Evelyn Chng, Director of ONERHT Foundation, Mr Bernard Tay, Director of ONERHT Foundation, Mr Ho Peng Kee, Patron of ONERHT Foundation, Mr Tan Chong Huat, Senior Partner of RHTLaw Asia, Ms Kaylee Kwok, Chairman and Director of ONERHT Foundation, Guest-of-Honour, Deputy Prime Minister and Minister for Trade and Industry Mr Gan Kim Yong, Mr Yang Eu Jin, Director of ONERHT Foundation, Mr Azman Jaafar, Managing Partner of RHTLaw Asia at the ONERHT Charity Golf 2024 Gala Dinner. [L-R]The gala dinner, held on 18 October 2024 at Sentosa Golf Club, was honoured by the presence of Guest-of-Honour, Deputy Prime Minister and Minister for Trade and Industry Mr Gan Kim Yong. The event successfully brought together more than 200 participants, including golfers and distinguished guests from various industry sectors.This year, to mark its 9th edition of the charity golf and gala dinner event, the Foundation has pledged to support a total of 9 beneficiaries. The beneficiaries are PAP Community Foundation Sparkle Care Centres, Life Community Services Society, Singapore Cancer Society, Singapore Road Safety Council, Bethel Community Services, Singapore Christian Home, South Central Community Family Service Centre, Focus on the Family Singapore Limited and Intercultural Theatre Institute. This demonstrates the Foundation’s commitment to reach out to a wider range of charities and support more beneficiaries.Ms Kaylee Kwok, Chairman of ONERHT Foundation, emphasised the importance of the Foundation’s work: “We are profoundly grateful for the generosity of our donors and sponsors, whose unwavering support propels our mission at ONERHT Foundation. Together, we are making significant strides towards fostering positive change within our community. We remain steadfast in our commitment to our core focus areas: education, environmental and sustainability, disadvantaged groups, and the arts and sports.”The donations made to various charitable organisations will enhance their programmes and services, allowing them to better serve their communities. This commitment to supporting a diverse range of individuals highlights the importance of community-driven initiatives that make a positive impact on the lives of those in need, such as empowering youth, caring for seniors, mentoring families, and providing comprehensive healthcare services, and much more.Ms Lam Moi Kwai, CEO of Life Community Services Society, shared her gratitude. “We extend our heartfelt gratitude to the ONERHT Foundation for their generous support over the years. The Foundation’s contributions play a vital role in empowering our LCSS beneficiaries, enabling us to provide essential care and mentoring to children and families in need. We thank the Foundation for being an invaluable partner in our mission."Ms Delia Ng, CEO, Focus on the Family Singapore, also said, “Thank you ONERHT Foundation for your generous support which would enable us to expand our outreach and equipping efforts for youths who aspire to become family champions through our FamChamps movement. Youths will be inspired in hope and empowered with the necessary mindset and resilience to break cycles of dysfunction and adversity.”Mr Victor Bay, CEO of PAP Community Foundation, shared, “PCF Sparkle Care is grateful for the support from ONERHT Foundation all these years. Their generous donation has enabled us to continue to provide programmes and care to the seniors whom we are so privileged to serve.”Similarly, Mr Albert Ching, CEO, Singapore Cancer Society, said, "The Singapore Cancer Society is honoured to have ONERHT Foundation join us in the collective fight against cancer. With the number of people living with cancer on the rise, the Foundation’s generous support strengthens our efforts to provide comprehensive cancer care services to beneficiaries at every stage of their journey. This includes free cancer screenings, welfare, rehabilitation support, hospice care, and public education initiatives. Thank you, ONERHT Foundation, for helping us minimise cancer and maximise lives!”Since its establishment in 2015, ONERHT Foundation has raised over S$5 million for more than 30 beneficiaries, demonstrating its commitment to fostering a more inclusive and supportive community in Singapore.ONERHT Foundation LtdA Singapore registered charity and grant-making philanthropic organisation, ONERHT Foundation Ltd (“Foundation”) enables RHTLaw Asia LLP and the RHT Group of Companies (collectively, “ONERHT”) to do right and do good through various charitable endeavours.Set up by ONERHT in 2015, the Foundation was registered as a Singapore charity by the Commissioner of Charities and a grant-making philanthropic organisation by the Inland Revenue Authority of Singapore on 16 September 2016 and 28 November 2016 respectively.The Foundation seeks to establish, inspire and encourage the right philanthropic culture among the corporate and legal fraternity of giving back to the community in a focused, hands-on and meaningful manner. Since its inception, the Foundation has raised over S$5 million to support more than 30 beneficiaries involved in education, the environment and sustainability, disadvantaged groups as well as the arts and sports.For more information, please visit www.onerht.foundationFor media enquiries, please contact:Elliot Siow / elliot@waterbrooks.com.sg / +65 8375 0417 Copyright 2024 ACN Newswire via SeaPRwire.com.
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GJK Facility Services Hosts Educational Session With Dr. Chantel Thornton During Breast Cancer Awareness Week ACN Newswire

GJK Facility Services Hosts Educational Session With Dr. Chantel Thornton During Breast Cancer Awareness Week

MELBOURNE, Oct 23, 2024 - (ACN Newswire via SeaPRwire.com) - In recognition of Breast Cancer Awareness Week, George Stamas, AM, Director of GJK Facility Services, organized a nationwide educational session featuring renowned breast cancer surgeon Dr. Chantel Thornton. This initiative aimed to raise awareness about the importance of early detection and regular breast cancer screenings.Dr. Chantel Thornton, Specialist Breast Cancer SurgeryDr. Thornton engaged with the GJK team in a live-streamed session, providing valuable insights and practical advice to employees across the country. She emphasized the critical role of early detection and prevention in effectively combating breast cancer. Dr. Thornton demonstrated self-examination techniques and stressed that regular checks significantly enhance the chances of early detection, which is key to successful treatment outcomes.This educational session not only raised awareness but also empowered participants with actionable knowledge to prioritize their health and well-being. It reflects GJK Facility Services' commitment to fostering a supportive workplace that values employee wellness.George Stamas is passionately committed to supporting the fight against breast cancer. His contributions include helping to secure funding for the second Trident Imaging System, a portable x�ray machine that is used during breast cancer surgery to help determine whether all the tumour cells have been removed.By prioritizing employee health and promoting early detection, GJK Facility Services demonstrates its dedication to creating a positive work environment that values the well-being of its team and their families.Dr. Chantel Thornton Specialist Breast Cancer Surgery MelbourneDr. Chantel Thornton is a Specialist Breast Cancer Surgeon utilising oncoplastic techniques who is passionate about delivering the highest standard of multidisciplinary care for patients with breast cancer. She has a special interest in the surgical management of young women with breast cancer and achieving the best oncological and cosmetic outcome and endorses immediate breast reconstruction post-mastectomy.Dr. Thornton completed a Bachelor of Medicine and Bachelor of Surgery with first-class honours from the University of Tasmania in the year 2000 and was dux of her medical school and received eight university prizes. She also has a Bachelor of Medical Science with honours, which was undertaken at The University of Hong Kong. In 2010, Dr. Thornton was awarded a fellowship from the Royal Australasian College of Surgeons. She completed fellowship training in breast cancer surgery at the Peter MacCallum Cancer Centre.Dr. Thornton is a fellow of the Australian Institute of Company Directors and has served on numerous philanthropic boards including the Alfred Hospital Foundation, the Foundation for Surgery and the Foundation for Breast Cancer Care. She is past chair of the Life Support Committee and member of the Epworth Special Events Committee.Dr. Thornton is founder and director of Specialist Breast Cancer Surgery and Specialist Cosmetic Centre. She established this purpose-built women's health centre with a dedicated team to enhance the treatment of patients with breast cancer. The centre aims to provide holistic care and improve the medical and psychological wellbeing of patients while delivering the very best breast cancer care.Contact InformationMedia Relations GJK Facility ServicesMediainfo@gjkfacilityservices.com.au1800635983Related ImagesDr. Chantel Thornton, Specialist Breast Cancer SurgeryDr. Chantel Thornton Presenting at GJK Facility ServicesDuring Breast Cancer Awareness Week, Dr. Chantel Thornton presented to GJK Facility Staff across Australia.Kaye, a Breast Cancer Survivor, Explaining Early DetectionSOURCE: GJK Facility Services Copyright 2024 ACN Newswire via SeaPRwire.com.
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Altezza Travel Wins Two Nominations at 2024 World Travel Awards ACN Newswire

Altezza Travel Wins Two Nominations at 2024 World Travel Awards

MOSHI, TANZANIA, Oct 23, 2024 - (ACN Newswire via SeaPRwire.com) - Altezza Travel has been named Tanzania's Leading Tour Operator and Tanzania's Leading Destination Management Company at the 2024 World Travel Awards. Since 1993, the awards have highlighted excellence across the global travel industry, recognizing top companies, destinations, and organizations.Altezza Travel team representatives receiving awardsAltezza Travel team representatives receiving awards at the 2024 World Travel Awards for Tanzania's Leading Tour Operator and Tanzania's Leading Destination Management Company.Mt. Kilimanjaro, a key destination for Altezza Travel, was also named "Africa's Leading Tourism Attraction," reaffirming the mountain's appeal as one of Africa's most sought-after travel destinations.Although it was their first nomination, Altezza Travel outperformed several previous winners to claim the title.While the organizers do not disclose the voting criteria, Altezza likely won for the following reasons:Kilimanjaro Leadership: Altezza Travel is the largest and fastest-growing operator of Kilimanjaro treks. In 2024 alone, they guided over 5,000 people to the summit of Kilimanjaro, more than any other operator, accounting for 15% of all successful climbs. The company experiences an annual growth rate of 20%, with thousands of positive reviews on platforms like TripAdvisor and Trustpilot, which likely played a key role in influencing the judges' decision.Outstanding Safety and Expertise: Travelers choose Altezza for its top-tier safety protocols, expert consultants, and high comfort standards on Kilimanjaro. Paying the highest wages in the region, Altezza attracts the best talent. The company has invested heavily in custom-designed tents and extensive guide training. In 2023, Altezza Travel's expertise earned them an invitation to Nepal, where their guides became the first Tanzanian guides to participate in a high-profile international expedition.Commitment to Social Responsibility: Altezza Travel's proactive social responsibility: the company has several ongoing projects with the Kilimanjaro National Park Authority. After the devastating fires in 2020 and 2022, which Altezza helped to extinguish, they provided fire-fighting equipment to the park and took part in a large-scale reforestation effort. Additionally, Altezza invests in numerous conservation initiatives and actively supports local communities.As of October 2024, Altezza Travel remains the leading operator for Kilimanjaro treks and wildlife safaris, setting the benchmark for excellence in Tanzania's tourism industry.For more information about Altezza Travel, visit https://altezzatravel.com/.Contact InformationThomas BeckerExpeditions Coordinatormarketing@altezza.travel+255786350216SOURCE: Altezza Travel Copyright 2024 ACN Newswire via SeaPRwire.com.
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李寧聯手紅杉中國成立合資公司 探索海外業務新路徑 ACN Newswire

李寧聯手紅杉中國成立合資公司 探索海外業務新路徑

香港, 2024年10月22日 - (亞太商訊 via SeaPRwire.com) - 李寧有限公司(「李寧」或「公司」,連同附屬公司,總稱「集團」;香港聯交所股份代號:2331(港幣櫃台)及 82331(人民幣櫃台))今天欣然宣佈,本公司之間接全資附屬公司LN Co與Founder Co、HongShan Venture、HongShan Motivation及合資公司訂立認購及股東協議,內容有關於英屬處女群島成立合資公司及各合資方認購合資股份。合資集團之目的為於地區獨家開發及經營李寧品牌業務(包括銷售李寧品牌產品)。緊隨完成後,合資公司之股本總額將為2億港元,其中LN Co、Founder Co、HongShan Venture及HongShan Motivation將分別以現金注資5,800萬港元、5,200萬港元、6,272.8萬港元及2,727.2萬港元,分別佔合資公司股本總額之29%、26%、31.36%及13.64%。本集團秉持「單品牌、多品類、多渠道」的核心戰略,在行業中發揮競爭優勢,並在激烈的國內市場競爭中取得了令人矚目的成績。但境外市場的發展,尤其是一帶一路地區的發展亦是本集團長遠發展戰略的一部分。同時,本集團也意識到境外市場存着諸多的不確定性,市場中的經營模式與中國內地市場的模式亦差異巨大。本集團考慮到拓展境外市場需要與具有豐富的跨國資源的合作方合作,共同成立一個全新的架構,在此架構之下組建一支獨立擁有豐富的海外資源和經驗的團隊負責操作,朝着明確的業務及財務目標去推進。紅杉中國在2005年成立以來已累計豐富的投資經驗,並建立了強大的具有深刻行業洞見的專業投資者團隊及跨境投資網絡,可為被投企業供應資源和服務,幫助從事跨境業務的企業部署在發展期中所需的關鍵資源,為其提供商業賦能、人才培養、數字化支持及媒體管理等服務。本次合資借力於本公司創始人李寧先生的號召力對品牌在海外市場發展的定位與方向的領導力,而且本公司和創始人李寧先生一併在合資公司中的持股達到55%,能有效地保障「李寧」品牌的聲譽和保持對合資公司足夠的影響力。另一方面,引入紅杉中國可讓合資公司分享紅杉中國的跨境資源及跨境業務經驗,有助於加快合資公司的發展步伐及效率。在本次合資中,LN Co有權在將來向紅杉中國收購合資公司的股份(在遵守上市規則的前提下),從而實現本公司對合資公司的控制。本次合資中各方優勢互補,以各自的聲譽、品牌、渠道、人才等資源最大化發揮在合資公司中的作用,讓合資公司在業務運營中能發揮競爭力和保持靈活性,並更有效地管理境外市場的風險。本公司短期內將更聚焦於中國內地市場業務,以增大核心業務的市場份額,增強品牌在核心業務細分市場上的競爭力。 Copyright 2024 亞太商訊 via SeaPRwire.com.
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Li Ning Partners with HongShan to Establish a Joint Venture ACN Newswire

Li Ning Partners with HongShan to Establish a Joint Venture

HONG KONG, Oct 22, 2024 - (ACN Newswire via SeaPRwire.com) - Li Ning Company Limited (“Li Ning” or the “Company”; together with the subsidiaries, the “Group”; stock codes: 2331 (HKD counter) and 82331 (RMB counter)) announces today that LN Co, being an indirect wholly-owned subsidiary of the Company, entered into the Subscription and Shareholders’ Agreement with Founder Co, HongShan Venture, HongShan Motivation and the JV Company in relation to the formation of the JV Company in the British Virgin Islands and subscription of JV Shares by each of the JV Parties. The purpose of the JV Group shall be to develop and operate the Li Ning Brand business (including the sale of products carrying Li Ning Brand) in the Territory on an exclusive basis.Immediately following Completion, the total share capital of the JV Company shall be HK$200 million, of which the LN Co, Founder Co, HongShan Venture and HongShan Motivaton shall contribute HK$58,000,000, HK$52,000,000, HK$62,728,000 and HK$27,272,000 in cash respectively, accounting for 29%, 26%, 31.36% and 13.64% of the total share capital of the JV Company respectively.The Group has been adopting the core strategy of “Single Brand, Multiple Categories, and Diversified Channels” to leverage its competitive advantages in the industry, and has achieved impressive results in the highly competitive Mainland China market. Having said that, the development of overseas markets, especially in the Belt and Road regions, is also part of the Group’s long-term development strategy. At the same time, the Group is aware of the uncertainties in the overseas markets. The business models in the overseas market also differ substantially from the models in the Mainland China market. The Group has considered that expanding into international markets requires collaboration with a partner which possesses extensive multinational resources. This requires the establishment of a new framework with an independent team, rich in overseas resources and experience, to take responsibilities of developing the international business operations with clear business and financial objectives.HongShan has accumulated extensive investment experience since its establishment in 2005. It has a strong team of professional investors with deep industry insights and cross-border investment networks that may provide resources and services to portfolio companies, deploy key resources to enterprises that engage in transnational businesses during their development stage, and provide them with services such as business empowerment, talent development, digitalisation support and media management.The formation of the JV Company leverages on the appeal of the Company’s founder, Mr. Li, to provide leadership in the positioning and direction of the Li Ning Brand’s development in the Territory. Moreover, the Company and Mr. Li together will hold 55% of the JV Shares, enabling the Company to effectively safeguard the reputation of the Li Ning Brand and to maintain sufficient influence over the JV Group. On the other hand, by bringing in HongShan, the JV Group may enjoy HongShan’s transnational resources and business experience which are expected to help the JV Group to accelerate its development effectively. In this joint venture, LN Co has the option to acquire all the JV Shares from HongShan Co in the future (subject to compliance with the relevant Listing Rules requirements), so as to realise the Company’s control over the JV Company.The JV Parties can complement each other’s strengths and leverage on their respective reputations, brands, channels, talents and other resources in this joint venture, in order to empower the JV Group to be competitive and flexible in its business operations, and be more effective in risk management of the markets in the Territory. In the short term, the Company will prioritise its operations in Mainland China market to further increase the market share of its core business and to enhance the competitiveness of its brands in the key business segments. Copyright 2024 ACN Newswire via SeaPRwire.com.
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Autobrains Unveils Skills Product Line, Redefining Autonomous Driving With Scalable and Modular AI Solutions ACN Newswire

Autobrains Unveils Skills Product Line, Redefining Autonomous Driving With Scalable and Modular AI Solutions

MUNICH, GERMANY & TEL AVIV, ISRAEL, Oct 22, 2024 - (ACN Newswire via SeaPRwire.com) - Autobrains, a leading innovator in automotive artificial intelligence (AI) and advanced driver assistance systems (ADAS), is proud to announce the launch of its groundbreaking product line, Skills, powered by its proprietary Liquid AI technology.Autobrains Unveils Skills Product LineEach Skill, End-to-End AI, is optimized for a specific driving scenario.The Skills product line represents a significant leap in autonomous driving technology, offering modular, scalable solutions that effectively address edge cases while reducing computational requirements compared to existing approaches.As the automotive industry accelerates toward full autonomy, Autobrains' new approach tackles the key limitations of traditional AI models by introducing a flexible and adaptive solution. While current end-to-end systems rely on a single, large neural network, or complex, resource-heavy compound systems, Autobrains' Skills solution delivers superior adaptability and efficiency."Our Skills product line represents a paradigm shift in autonomous driving," said Igal Raichelgauz, Founder and CEO of Autobrains. "With Skills, we offer a flexible, scalable AI solution that can be deployed incrementally, starting with ADAS and extending toward full autonomy. Unlike other approaches, our system's adaptability ensures that as new edge cases emerge, the required resources increase only logarithmically, providing a significant improvement over demands seen with other approaches."Existing autonomous driving solutions face substantial challenges in handling edge cases, which demand new, more adaptive AI technologies. Compound architectures, like those employed by Mobileye, divide tasks into separate modules, resulting in an information bottleneck. Monolithic end-to-end systems like Tesla's Full Self-Driving (FSD) suite face issues with explainability, transparency, and efficiency in adapting to new scenarios.Autobrains' Skills architecture addresses these issues by decomposing autonomous driving into a collection of smaller, context-specific AI models - referred to as "Skills"-each trained and deployed independently. These Skills are activated dynamically based on the driving situation, optimizing performance and significantly reducing computational power demands.Key advantages of the Autobrains' Skills product line include:Optimized for Edge Cases: Each Skill is optimized to handle specific driving scenarios, leading to superior performance in edge cases.Scalability: The Skills architecture can expand from tens of skills for ADAS applications to hundreds of thousands for full autonomy.Adaptability: Skills are activated only when relevant, minimizing power consumption.Logarithmic Resource Growth: Unlike models that require exponentially more resources as they scale, the Skills architecture allows for more efficient, logarithmic resource expansion.Enhanced Safety: By focusing on specific edge cases, Skills provide precise, targeted responses, enhancing overall system safety.Autobrains is actively collaborating with major OEMs worldwide, testing and implementing the Skills product line to transform the future of autonomy. This cutting-edge AI architecture is poised to lower costs, improve safety, and drive the next wave of smarter, more efficient autonomous driving systems.For more information about Autobrains and its Skills technology, please visit www.autobrains.ai.Contact InformationSophia EichlerDirector of Marketingmedia@autobrains.ai+49 15167066494SOURCE: Autobrains Copyright 2024 ACN Newswire via SeaPRwire.com.
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USPA Global Announces Strategic Broadcast Association With Star Sports, Reaching Millions of Polo Sports Fans Across India ACN Newswire

USPA Global Announces Strategic Broadcast Association With Star Sports, Reaching Millions of Polo Sports Fans Across India

WEST PALM BEACH, FL AND MUMBAI, INDIA, Oct 22, 2024 - (ACN Newswire via SeaPRwire.com) - USPA Global, the company that manages the multi-billion-dollar U.S. Polo Assn. brand, is proud to announce a landmark, multi-year broadcasting association with Star Sports, India's leading sports network and part of Disney's family of networks. This partnership is part of USPA Global's broadcasting subsidiary, Global Polo Entertainment (GPE), and launched in October.U.S. Polo Assn.This strategic association marks an innovative collaboration intended to bring polo sport content and the iconic U.S. Polo Assn. brand to engaged sports and brand fans in the very important and growing Indian market. This collaboration brings the thrilling world of polo directly to millions of homes across the Indian subcontinent, including India, Bangladesh, Bhutan, Maldives, Nepal, and Sri Lanka. The sport of polo will now reach even more viewers around the world, adding to current partnerships with ESPN and beIN Sports."Joining forces with Star Sports represents a significant step in our U.S. Polo Assn. market strategy to authentically engage with sports fans and consumers in one of our fastest growing and largest markets," said J. Michael Prince, President and CEO of USPA Global. "As the number one men's casualwear brand in India, U.S. Polo Assn. already has a strong presence with consumers, and this partnership will now build that same relationship across the Indian market with our mission to promote the sport of polo globally."The Star Sports association begins the season with the award-winning series, Breakaway, a story-driven program where fans can see episodes covering the most prestigious tournaments, women's polo, and polo in England. Each episode will spotlight notable figures, such as U.S. Polo Assn.'s Global Brand Ambassador His Highness Maharaja Sawai Padmanabh Singh (Pacho) of Jaipur along with Indian Polo and the Jaipur Team, as well as world-renowned players such as Hope Arellano, Adolfo Cambiaso, Jeta Castagnola, and many more."As the brand licensee of U.S. Polo Assn. in India, Arvind Fashions is incredibly proud to be part of this partnership that is bringing such exciting sports entertainment to our consumers and all sports fans in India," said Shailesh Chaturvedi, CEO & Managing Director of Arvind Fashions Ltd., U.S. Polo Assn.'s Strategic Partner. "Making further inroads into sports in India is a significant step in the history of the U.S. Polo Assn. brand and what makes this market-leading brand truly authentic."By aligning with Star Sports, U.S. Polo Assn. is now part of the multi-sport environment in the Indian sports broadcasting scene. The network's extensive coverage includes premier sporting events such as cricket with Tata India Premier League (IPL), Premier League Football, and Wimbledon."Embracing the sport of polo as part of our diverse sports culture aligns perfectly with our mission to expand our sports offerings and engage with a broader audience," said Harry Griffith, Head of Acquisition and Syndication at Star Sports. "We are excited to introduce our viewers to the rich history and dynamic action of polo through our collaboration with USPA Global and the U.S. Polo Assn. brand."About U.S. Polo Assn. and USPA GlobalU.S. Polo Assn. is the official brand of the United States Polo Association (USPA), the governing body for the sport of polo in the United States and one of the country's oldest sports governing bodies, founded in 1890. With a multi-billion-dollar global footprint and worldwide distribution through more than 1,100 U.S. Polo Assn. retail stores as well as thousands of additional points of distribution, U.S. Polo Assn. offers apparel, accessories, and footwear for men, women, and children in more than 190 countries worldwide. A historic, multi-year deal with ESPN to broadcast several of the premier polo championships in the world, sponsored by U.S. Polo Assn., has made the thrilling sport accessible to millions of sports fans globally for the very first time.U.S. Polo Assn. has consistently been named one of the top global sports licensors in the world alongside the NFL, NBA, and MLB, according to License Global. In addition, the sport-inspired brand is being recognized internationally with awards for global and digital growth. Due to its tremendous success as a global brand, U.S. Polo Assn. has been featured in Forbes, Fortune, Modern Retail, and GQ as well as on Yahoo Finance and Bloomberg, among many other noteworthy media sources around the world.For more information, visit uspoloassnglobal.com and uspashop.com, and follow @uspoloassn.USPA Global is a subsidiary of the USPA and manages the global, multi-billion-dollar U.S. Polo Assn. brand. Through its subsidiary, Global Polo Entertainment (GPE), USPA Global also manages Global Polo TV, which provides sports and lifestyle content. For more sports content, visit globalpolo.com.About Star SportsThe Star Sports Network is home to several leading domestic and international sports with seventeen channels broadcasting premier sporting events which include cricket coverage under the purview of the TATA Indian Premier League (IPL), International Cricket Council (ICC), Cricket South Africa and Cricket Australia; Kabaddi under Pro Kabaddi League; and premier sports with Premier League; and Wimbledon amongst others.Contact InformationShannon StilsonVP, Sports Marketing & Mediasstilson@uspagl.com+001.561.227.6994Stacey KovalskySenior Director, Global Communicationsskovalsky@uspagl.com+001.561.790.8036Rohan D'souzaStar Sports PRrohan.dsouza@disney.com+91 9833834146SOURCE: USPA Global Licensing Inc. Copyright 2024 ACN Newswire via SeaPRwire.com.
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Kincora Announces Cutting-Edge Geophysics Confirms High Priority Drill Target At The Nyngan Project ACN Newswire

Kincora Announces Cutting-Edge Geophysics Confirms High Priority Drill Target At The Nyngan Project

Ambient Noise Tomography (ANT) and gravity geophysical surveys (the "Surveys") have confirmed and refined a regionally significant priority porphyry target located within the "Ace of Spades" region at the Nyngan Project ahead of imminent drill testingThe first ever copper-gold focused drilling program has recently commenced 1 at the northern portion of the Nyngan Project testing new porphyry district-scale potential with 6-8 drill holes for an estimated 4000-5000 metres scheduled before the end of yearThe Surveys also cover the location of a second designed hole and identified a number of new potential areas of interest also within the "Ace of Spades" region that will be reviewed in light of the results of the commenced drilling program in conjunction earn-in partner AngloGold Ashanti Australia (AngloGold Ashanti)The Surveys apply cutting-edge technology utilising the first ever integrated real-time ANT and ground gravity undertaken by Fleet Space Technologies Pty Ltd (Fleet Space) and complement Kincora and AngloGold Ashanti's planned drilling via an up to $50 million earn-in and joint venture agreement for the Nyngan and Nevertire ProjectsKincora has recently expanded its partnership with Fleet Space to include: (i) a listed equity investment, (ii) multiphysics surveys at the Wongarbon Project to identify and refine targets, and, (iii) Fleet Space having the right to drill test targets to earn an asset level interest in the Wongarbon Project 2.Melbourne, Australia--(ACN Newswire via SeaPRwire.com - October 22, 2024) - Kincora Copper Limited (TSXV: KCC) (ASX: KCC) (Kincora or the Company) is pleased to announce the initial interpretations from new geophysical surveying at a portion of the northern "Ace of Spades" region of the Nyngan Project, located in the Northern Junee-Narromine Belt (NJNB) of the Macquarie Arc, Central West New South Wales.Sam Spring, President and CEO of Kincora commented: "The geophysical surveys are being conducted in partnership with Fleet Space and include the first ever integration of gravity with a real-time ANT survey completed by Fleet Space. The Cadia intrusive system complex has a ~5.7km footprint, seven deposits within it, with regional geophysics able to identify key structures and geological units. What we are seeking to confirm in our first phase of drilling at Nyngan is the potential for multiple new Macquarie Arc intrusive system complexes that have similar multi-kilometre alteration zones and multiple deposit potential. The initial results from the Fleet Space surveys, coupled with existing regional geophysics, are positive providing a more detailed and refined geophysical model for an existing a high priority and large-scale target that is about to be drilled within the Ace of Spades region. The Ace of Spades is a very compelling new district scale opportunity, potentially the largest volcano-intrusive complex of the Macquarie Arc and has never been drilled.We are now in a very exciting period with the 6 to 8-hole program commenced. This program will drill a range of large-scale and separate intrusive system targets, focused on the Ace of Spades, within an existing pipeline of 16 targets that are permitted for drilling within the northern portion of the Nyngan Project."Background Fleet Space's real-time Ambient Noise Tomography (ANT) and ground gravity surveys, enabled by their end-to-end mineral exploration solution, Exosphere, are the first integrated surveys completed by Fleet Space and seek to apply cutting-edge technology to generate and interpret new homogeneous, primary datasets with existing regional geophysical surveys and geological data.The surveys have confirmed and refined a regionally significant priority drill target previously and separately identified by Kincora, AngloGold Ashanti and Fleet Space within the northern "Ace of Spades" region of the Nyngan Project. Existing regional geophysics strongly indicates that the Nyngan Project potentially hosts the largest volcano-intrusive complex of the Macquarie Arc offering new district scale potential situated in the northern under cover extension of the Arc - see Figure 1.It is well documented that the composite volcanic and intrusive complexes elsewhere in the Macquarie Arc, which hosts an estimated total mineral endowment of over 160Moz gold equivalent 3, have large alteration and geochemical halos that are often identifiable from regional geophysical surveys. For example the magmatic and alteration footprints at Cadia have a ~5.7km wide footprint, hosting two skarn and five porphyry deposits with a metal endowment of more than 50Moz gold and more than 9.5Mt copper 3, and regional geophysics is able to identify key structures and geological units (see Figure 2 for an illustration). Similar large geophysical features are present at the Nyngan Project and the survey area. Furthermore, the mineralised deposits in the Arc (including Cadia) and other globally significant porphyry districts generally occur in clusters situated on cross-arc structures. Similar structures have been identified by the Fleet Space surveys inline with existing regional geophysics - see Figures 1-3.Two existing 2024 field season Kincora and AngloGold Ashanti drill targets were covered by the Fleet Space surveys and are to be very shortly drill tested as part of the first ever copper-gold focused drilling program within the Ace of Spades. A 6 to 8-hole for an estimated 4000-5000m program has commenced and is scheduled before the end of year with earn-in partner AngloGold Ashanti within an existing pipeline of 16 targets that are permitted for drilling within the northern portion of the Nyngan Project.Confirmed and Refined High Priority Target at the Ace of SpadesThe Fleet Space multiphysics surveys have combined proprietary ground exploration techniques that minimise environmental impact by utilising seismic noise derived from natural and anthropogenic sources (two ANT surveys complete), with new gravity (two ground gravity surveys complete) and existing public access regional airborne magnetics and gravity.Intergration of these datasets have sought to:(i) identify and refine targeting of new composite volcanic and intrusive complexes,(ii) map the depth to basement,(iii) refine key structural features, and,(iv) identify changes in velocity and density that may reflect different lithological units.The regional ANT survey covered an area of approximately 35km2 with a tighter spaced infill and ground gravity survey area of approximately 9km2. Similar to other Fleet Space surveys in the district, the ANT velocity model provides a depth profile to approximately 2500m and 1000m in the infill survey.This marks the first time a Fleet Space real-time ANT survey has been accompanied by an integrated and coincident ground gravity survey to deliver complimentary nearer surface density models.The initial interpretation of the Nyngan multiphysics results have confirmed and refined an existing high priority drill target with several features of interest at both a regional and infill survey level having potential implications for future exploration.(i) Regional ANT survey results highlights:Multiple deep-seated structures consistent with existing magnetics and gravity features, refining interpreted potential cross-arc structures and separate target domains that may have influenced the emplacement of intrusions.Supported the potential for multiple volcanic and intrusive complexes.Average depth to basement of ~360m across the survey area.Identified a number of potential new areas of interest with low seismic velocity zones in the basement sequence (interpreted to potentially be related to hydrothermal alteration), near edges and/or above high seismic velocity bodies (interpreted to potentially be related to large intrusions at depth).(ii) Infill ANT and gravity survey highlights:Higher resolution of interpreted structures, with velocity and density models refining potential lithological domains, structures and cross-arc structures.Supported the potential for multiple intrusive stocks and additional drill hole targets.Confirms and refines an existing high priority drill target with the originally proposed drill hole collar moved ~400m.Imminent drilling will test a large scale target off the shoulder of a pronounced density and magnetic anomaly associated with a potential cross-arc structure and into a low-intermediate seismic velocity zone (interpreted to potentially be related to hydrothermal alteration and/or mineralisation) that lies above a high seismic velocity anomaly at depth (interpreted to potentially relate to a Macquarie Arc intrusion) - see Figure 3.The commenced drilling program is expected to provide enhanced geological understanding of the geophysical models resulting from the Fleet Space multiphysics surveys. Such learnings are expected to assist Kincora with future exploration and drill hole targeting at both the Nyngan Project, the recently expanded partnership with Fleet Space for the Wongarbon Project and the Company's existing pipeline of eleven other porphyry projects in the Macquarie Arc.New Potential Drill Targets At the Ace of SpadesCurrently Kincora and AngloGold Ashanti have an existing pipeline of 16 targets that are permitted for drilling within the northern portion of the Nyngan Project - see Figure 2. Two of these proposed for drilling before year-end are included in the Fleet Space survey area with a further two permitted covered by the regional ANT.Similar to other project level ANT surveys recently undertaken by Fleet Space in the Macquarie Arc at Waratah Minerals Limited's Spur Project ("Waratah", WTM.ASX) 4 and Inflection Resource's Duck Creek Project ("Inflection", AUCU.CSE) 5,6, a number of additional areas of potential interest for new large intrusive porphyry systems and potential drill targets have been identified in the Ace of Spades region.Inflection has been using Fleet Space ANT survey results, coupled with existing regional geophysics, as a key exploration tool in its drill hole targeting at Duck Creek.Results from down-hole geophysical surveying have reported zones of relatively high seismic/shear-wave velocity associated with competent intervals of monzodiorite, which supports the hypothesis that intrusions are likely to manifest in the ANT data as zones of elevated seismic velocity. Additionally, the surveying demonstrates localised areas of low seismic velocity associated with more intense hydrothermal alteration, which also supports the interpretation that low seismic velocities evident in the ANT survey can represent zone of hydrothermal alteration 7.The results of the multiphysics surveys at Nyngan will be reviewed in light of the commenced drilling program results in conjunction with AngloGold Ashanti and are expected to also assist with Fleet Space and Kincora's partnership for the Wongarbon Project.Further New District-Scale Opportunities Prospective early stage porphyry positions in the interpreted undercover extensions of the Macquarie Arc that offer new district scale potential have recently been the focus of five large earn-in and joint venture agreements supporting potentially over $300 million of exploration expenditure covering over 10,000km2. Most recently, only in August, Gold Field's re-entered the Macquarie Arc via a multiple phase, multiple project option agreement with a private explorer, Gold and Copper 8.Spatial and temporal settings, coupled with magnetics, gravity and ANT surveys, supports new district scale potential and that the largest sections of the Macquarie Arc may be located under post mineral cover.Kincora was an early entrant pursuing this strategy, securing a significant portion of the most prospective and shallow to moderate depth sections of this underexplored (often never drilled) sections of the Macquarie Arc.The Company is discussing further partnership opportunities with Fleet Space, amongst other groups, and notes the recent results of the Fleet Space and Inflection district scale ANT survey (>1800km2) which, when integrated with other existing datasets (including airborne magnetics and gravity), has resulted in four new priority targets, three of which commence within 2km's of Kincora's wider project portfolio (four if Duck Creek is included) in the Northern Junee-Narromine Belt (NJNB) 6 - see Figure 1.Kincora has recently secured three new wholly owned licenses covering 1,377km2 (the Nyngan West, Nyngan South and Nevertire South Projects) providing a continuous landholding along >100km strike of the NJNB (see Figure 1) 9 with a recent extremely positive review of the new Nevertire South Project supporting what Kincora believes is the most attractive geologically supported target in the covered extensions of the Macquarie Arc 10.Coupled with the highly prospective Wongarbon Project11, located on the northern Molong Belt, Kincora is seeking to confirm multiple new district-scale and porphyry discovery potential. Figure 1: Multiple Fleet Space surveys, existing regional magnetics and gravity surveys, and limited drilling to date supports Kincora and AngloGold Ashanti's interpretation that the Northern Junee-Narromine Belt hosts the potential for multiple new composite volcanic and intrusive complexes with analogous aeromagnetic signatures and intrusive level cross arc structures to other Macquarie Arc porphyry complexes (eg Cadia, Cowal, Boda-Kaiser, Marsden etc)The Macquarie Arc is a proven Tier 1 terrane and Australia's foremost copper porphyry belt hosting a number of world-class mines in the southern, more exploration mature, of the Arc hosting over 160Moz gold equivalent endowment.To view an enhanced version of this graphic, please visit:https://images.newsfilecorp.com/files/2305/227375_dafda03364be6bf7_001full.jpg Figure 2: Fleet Space's ANT and gravity surveys have refined a regionally significant priority drill target previously and separately identified by Kincora, AngloGold Ashanti and Fleet Space within the northern "Ace of Spades" region of the Nyngan Project. This target is to be very shortly drill tested as part of the first ever copper-gold focused drilling program within this region. As part of a permitted drill program for up to 16 holes, a 6 to 8-hole for an estimated 4000-5000m program is budgeted before year-end with earn-in partner AngloGold Ashanti.Kincora and Inflection's recent real-time Fleet Space ANT surveys have generated a number of new, previously unrecognised potential target areas that are currently being reviewed.To view an enhanced version of this graphic, please visit:https://images.newsfilecorp.com/files/2305/227375_dafda03364be6bf7_002full.jpg Figure 3: Imminent drilling will test a large-scale target off the shoulder of a pronounced density and magnetic anomaly associated with a potential cross-arc structure and into a low-intermediate seismic velocity zone (interpreted to potentially be related to hydrothermal alteration and/or mineralisation) that lies above a high seismic velocity anomaly at depth (interpreted to potentially be an intrusion) - illustration sourced from Fleet Space's Exosphere.The Fleet Space surveys across the Macquarie Arc have identified and refined existing targets of new composite volcanic and intrusive complexes, mapped estimated depth to basement, refined key structural features (including cross-arc structures), and, identified changes in velocity and density that may reflect different lithological units.To view an enhanced version of this graphic, please visit:https://images.newsfilecorp.com/files/2305/227375_dafda03364be6bf7_003full.jpgAbout the Nyngan ProjectThe Nyngan Project was the first ground Kincora secured in NSW 12 with regional geophysics strongly indicating the potential to hosts the largest volcano-intrusive complex of the Macquarie Arc (existing metal endowment of over 160Moz gold equivalent) and offering a new district-scale setting. Limited prior drilling activities have taken place, and are limited to the southern portion of the Project.In May 2024, Kincora signed a definitive multiple-phase Earn-in and Joint Venture Agreement over the Nyngan and Nevertire licences with a wholly owned subsidiary of AngloGold Ashanti plc (NYSE: AU; JSE: ANG), the world's fourth largest gold miner by production, which has a successful track record for Greenfields discovery success.AngloGold Ashanti has the right to spend up to A$50 million to earn an 80% interest through:A$25 million of exploration expenditure to earn a 70% joint venture interest (Phase I) including a minimum A$2 million expenditure obligation, with Kincora the initial operator for a 10% management fee.Completion of a Pre-Feasibility Study (PFS) or funding of a further $25 million of expenditure to earn a 80% joint venture interest (Phase II) 13.The commenced drilling program is focused within the northern portion of the Nyngan Project and the "Ace of Spades" region testing a wide range of untested, large intrusive-related copper-gold targets. The program will comprise cost-effective mud-rotary drilling through the post mineral cover sequence with diamond core drilling upon refusal and testing of the targeted basement. The program seeks to confirm the potential for a series of new Macquarie Arc intrusive complexes and provide vectors for follow up drilling.About Fleet Space Technologies Fleet Space is widely regarded as Australia's leading space company and is seeking to revolutionise mineral exploration with its vertically integrated technology sack, ExoSphere, which combines the latest advances in satellite connectivity, 3D multiphysics data acquisition, and AI to map mineral systems in real-time.Fleet Space's ExoSphere technology enables an end-to-end approach to high-quality data acquisition, processing, interpretation and targeting to streamline exploration and improve success rates for new economic discoveries.Leveraging Fleet Space's proprietary satellite network in low Earth orbit, smart seismic sensors enabled with edge computing and rapid data processing ExoSphere delivers real-time 3D mapping of mineral systems and AI-powered drill targeting with near-zero environmental impact.In the last quarter, Barrick Gold announced it would partner with Fleet Space to survey copper porphyry complexes across 1,150km² of the world-class Reko Diq project 14 and in the last month Gold Fields announced a similar relationship to advance exploration at the Salares Norte project in Chile 15.Recently, Inflection Resources' announced new targets generated by ExoSphere, leading AngloGold to accelerate their Exploration Agreement and drilling with Inflection 5. Inflection and Fleet Space have also recently announced the results of the world's largest real-time ANT survey across 1818km², built an AI-powered district scale copper prospectivity map which, when integrated with other existing datasets (including airborne magnetics and gravity), has resulted in four new priority targets, three of which are within 2km's of Kincora wider project portfolio in the northern Junee-Narromine Belt.In July 2024, Kincora formed an initial partnership to conduct the first ever integrated real-time ANT and ground gravity undertaken by Fleet Space within the "Ace of Spades" region at the Nyngan Project.In mid October 2024, Kincora expanded its partnership with Fleet Space to include: (i) a listed equity investment, (ii) multiphysics surveys at the Wongarbon Project to identify and refine targets, and, (iii) Fleet Space having the right to drill test targets to earn an asset level interest in the Wongarbon Project.ExoSphere's rapid global adoption has propelled Fleet Space's exponential growth, including a A$50 million Series C funding round, a doubling of its valuation to A$350 million, plans to send a variant of ExoSphere to the Moon in 2026, and recognition as Australia's fastest growing company by the Australian Financial Review (2023).For more information please visit Fleet Space's website at https://www.fleetspace.com.About Kincora Kincora Copper is dual listed on the ASX and TSX-V (ticker "KCC") and is an active explorer and project generator focused on world-class copper-gold discoveries that has recently executed five agreements that unlock over A$60 million in potential multiple year partner funding. Further new projects that offer a clear value path and targeted partnerships are proposed.Kincora's portfolio includes district scale landholdings and scale-able drill ready targets in both Australia and Mongolia's leading porphyry belts, the Macquarie Arc and Southern Gobi, respectively, and, the Company is targeting exposure to 10,000-30,000m pa of drilling.For more information please visit Kincora's website at www.kincoracopper.com.References:1 Three Kincora Partner Funded Drilling Programs Ramping Up - Kincora press release October 7, 20242 Kincora announces Strategic Investment and Expanded Partnership with Fleet Space - press release October 15, 20243 Sourced from MinEx Consulting for Kincora4 ANT geophysics defines additional epithermal-porphyry targets at Spur Project - Waratah press release May 23, 20245 Reimaging porphyry copper exploration using Exosphere: Ambient Noise Tomography from the Duck Creek project, Macquarie - Fleet and Inflection Case Study 2023 6 Inflection Resources Defines New Priority Targets Based on Results of Regional ANT Survey in New South Wales - Inflection press release September 12, 20247 Inflection Resources Provides Drilling Update from Phase II Duck Creek Exploration Program in New South Wales - Inflection press release October 3, 20248 Gold Fields H1 2024 Results - August 23, 20249 Kincora Secures New Strategic Ground On Australia's Premier Porphyry Copper-Gold Province - Kincora press release September 9, 202410 Three Kincora Partner Funded Drilling Programs Ramping Up - Kincora press release October 7, 202411 New Major, Virgin Porphyry Complex And Drill Targets Secured - Kincora press release June 3, 202412 Kincora secures strategic license in Australia's leading porphyry belt - Kincora press release November 21, 201913 AngloGold Ashanti to earn-in to the NJNB Project - Kincora press release May 28, 202414 Fleet Space's Exosphere Enhances Barrick Gold's Data-Driven Copper Exploration at Reko Diq - Fleet Space press release July 9, 202415 Gold Fields Taps ExoSphere To Advance Exploration at Salares Norte in Chile - Fleet Space press release October 3, 2024This announcement has been authorised for release by the Board of Kincora Copper Limited (ARBN 645 457 763)For further information please contact: Sam Spring, President and Chief Executive Officersam.spring@kincoracopper.com or +61431 329 345Executive office 400 - 837 West Hastings StreetVancouver, BC V6C 3N6, Canada Tel: 1.604.283.1Fax: 1.888.241.5996Subsidiary office Australia Vista Australia Level 4, 100 Albert RoadSouth Melbourne, Victoria 3205Qualified PersonThe scientific and technical information in this announcement was prepared in accordance with the standards of the Canadian Institute of Mining, Metallurgy and Petroleum and National Instrument 43-101 - Standards of Disclosure for Mineral Projects ("NI 43-101") and was reviewed, verified and compiled by Kincora's staff under the supervision of Peter Leaman (M.Sc. Mineral Exploration, FAusIMM), Senior Vice-President of Exploration of Kincora, and John Holliday (BSc Hons, BEc, member of the Australian Institute of Geoscientists), Non-Executive Director and Chairman of Kincora's Technical Committee, who are Qualified Persons for the purpose of NI 43-101. JORC Competent Person StatementInformation in this announcement that relates to Exploration Targets, Exploration Results, Mineral Resources or Ore Reserves is based on information reviewed and approved by John Holliday and Peter Leaman, who are Competent Person(s) under the definition established by JORC and has sufficient experience which is relevant to the style of mineralisation and type of deposit under consideration and to the activity being undertaking to qualify as a Competent Person as defined in the 2012 Edition of the 'Australasian Code for Reporting of Exploration Results, Mineral Resources and Ore Reserves'. John Holliday and Peter Leaman consent to the inclusion in this report of the matters based on the information in the form and context in which it appears. The review and verification process for the information disclosed herein for Kincora's projects have included the receipt of all material exploration data, results and sampling procedures of previous operators, contractors, new results and review of such information by Kincora's geological staff using standard verification procedures.Forward-Looking StatementsCertain information regarding Kincora contained herein may constitute forward-looking statements within the meaning of applicable securities laws. Forward-looking statements may include estimates, plans, expectations, opinions, forecasts, projections, guidance or other statements that are not statements of fact. Although Kincora believes that the expectations reflected in such forward-looking statements are reasonable, it can give no assurance that such expectations will prove to have been correct. Kincora cautions that actual performance will be affected by a number of factors, most of which are beyond its control, and that future events and results may vary substantially from what Kincora currently foresees. Factors that could cause actual results to differ materially from those in forward-looking statements include market prices, exploitation and exploration results, continued availability of capital and financing and general economic, market or business conditions. The forward-looking statements are expressly qualified in their entirety by this cautionary statement. The information contained herein is stated as of the current date and is subject to change after that date. Kincora does not assume the obligation to revise or update these forward-looking statements, except as may be required under applicable securities laws.Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) or the Australian Securities Exchange accepts responsibility for the adequacy or accuracy of this release.JORC TABLE 1Section 1 Sampling Techniques and Data(Criteria in this section apply to all succeeding sections).CriteriaJORC Code explanationCommentarySampling techniquesNature and quality of sampling (e.g., cut channels, random chips, or specific specialised industry standard measurement tools appropriate to the minerals under investigation, such as down hole gamma sondes, or handheld XRF instruments, etc.). These examples should not be taken as limiting the broad meaning of sampling.Include reference to measures taken to ensure sample representivity and the appropriate calibration of any measurement tools or systems used.Aspects of the determination of mineralisation that are Material to the Public Report.In cases where 'industry standard' work has been done this would be relatively simple (e.g., 'reverse circulation drilling was used to obtain 1 m samples from which 3 kg was pulverised to produce a 30 g charge for fire assay'). In other cases, more explanation may be required, such as where there is coarse gold that has inherent sampling problems. Unusual commodities or mineralisation types (e.g., submarine nodules) may warrant disclosure of detailed informationNot applicable: Ground geophysical surveysDrilling techniquesDrill type (e.g., core, reverse circulation, open-hole hammer, rotary air blast, auger, Bangka, sonic, etc) and details (e.g., core diameter, triple or standard tube, depth of diamond tails, face-sampling bit or other type, whether core is oriented and if so, by what method, etc.).Not applicable: Ground geophysical surveysDrill sample recoveryMethod of recording and assessing core and chip sample recoveries and results assessed.Measures taken to maximise sample recovery and ensure representative nature of the samples.Whether a relationship exists between sample recovery and grade and whether sample bias may have occurred due to preferential loss/gain of fine/coarse material.Not applicable: Ground geophysical surveysLoggingWhether core and chip samples have been geologically and geotechnically logged to a level of detail to support appropriate Mineral Resource estimation, mining studies and metallurgical studies.Whether logging is qualitative or quantitative in nature. Core (or costean, channel, etc.) photography.The total length and percentage of the relevant intersections logged.Not applicable: Ground geophysical surveysSub-sampling techniques and sample preparationIf core, whether cut or sawn and whether quarter, half or all core taken.If non-core, whether riffled, tube sampled, rotary split, etc. and whether sampled wet or dry.For all sample types, the nature, quality and appropriateness of the sample preparation technique.Quality control procedures adopted for all sub-sampling stages to maximise representivity of samples.Measures taken to ensure that the sampling is representative of the in-situ material collected, including for instance results for field duplicate/second-half sampling.Whether sample sizes are appropriate to the grain size of the material being sampled.Not applicable: Ground geophysical surveysQuality of assay data and laboratory testsThe nature, quality and appropriateness of the assaying and laboratory procedures used and whether the technique is considered partial or total.For geophysical tools, spectrometers, handheld XRF instruments, etc, the parameters used in determining the analysis including instrument make and model, reading times, calibrations factors applied and their derivation, etc.Nature of quality control procedures adopted (e.g., standards, blanks, duplicates, external laboratory checks) and whether acceptable levels of accuracy (i.e., lack of bias) and precision have been established.Not applicable: Ground geophysical surveysFleet Space Technologies Pty Ltd (Fleet Space Technologies) completed a 14-day Ambient Noise Tomography (ANT) Survey. One hundred (100) Geodes® (Geodes) plus spares enabled for real-time data acquisition and uplink, including live survey monitoring tools via ExoSphere Cloud interfaceData processing uses 3D shear velocity models generated via Fleet Space Technologies' proprietary automated data processing in ExoSphere Cloud, which allows unlimited user access to view and export 3D model resultsAmbient noise tomography uses the Earth's background hum as the signal for measuring subsurface velocity structure. An array of seismic sensors (Geodes) records ambient seismic noise created by natural and anthropogenic sources from which the travel-times of surface waves between pairs of Geodes is extracted via the process of cross-correlation and stacking. This technique effectively transforms each pair into a virtual source-receiver pair, from which the phase velocity versus frequency relationship (dispersion) can be measured and used to model the subsurface velocity structureNot applicable: Ground geophysical surveysVerification of sampling and assayingThe verification of significant intersections by either independent or alternative company personnel.The use of twinned holes.Documentation of primary data, data entry procedures, data verification, data storage (physical and electronic) protocols.Discuss any adjustment to assay data.Not applicable: Ground geophysical surveysLocation of data pointsAccuracy and quality of surveys used to locate drill holes (collar and down-hole surveys), trenches, mine workings and other locations used in Mineral Resource estimation.Specification of the grid system used.Quality and adequacy of topographic control.Not applicable: Ground geophysical surveysHandheld GPS location and height control is considered adequate for early-stage exploration geophysical surveyingData spacing and distributionData spacing for reporting of Exploration Results.Whether the data spacing and distribution is sufficient to establish the degree of geological and grade continuity appropriate for the Mineral Resource and Ore Reserve estimation procedure(s) and classifications applied.Whether sample compositing has been applied.At the exploration stage, data spacing is variable and designed to understand the nature and controls on mineralisationResults are considered early stage, with the nature and controls on mineralisation still being establishedNot applicable: Ground geophysical surveysOrientation of data in relation to geological structureWhether the orientation of sampling achieves unbiased sampling of possible structures and the extent to which this is known, considering the deposit type.If the relationship between the drilling orientation and the orientation of key mineralised structures is considered to have introduced a sampling bias, this should be assessed and reported if material.The orientation of the grid isn't relevant to the outcome of the ANT data collectionAn array of seismic sensors (Geodes) records ambient seismic noise created by natural and anthropogenic sources from which the travel-times of surface waves between pairs of Geodes is extracted via the process of cross-correlation and stacking. This technique effectively transforms each pair into a virtual source-receiver pair, from which the phase velocity versus frequency relationship (dispersion) can be measured and used to model the subsurface velocity structureSample securityThe measures taken to ensure sample security.Not applicable: Ground geophysical surveysAudits or reviewsThe results of any audits or reviews of sampling techniques and data.Not applicable: Ground geophysical surveys but noting multiple conference calls, reviews and interpretations of the regional ANT, infill ANT and ground gravity survey parameters, assumptions, results and interpretations by Kincora's team. Section 2 Reporting of Exploration Results(Criteria listed in the preceding section also apply to this section.)CriteriaJORC Code explanationCommentaryMineral tenement and land tenure statusType, reference name/number, location and ownership including agreements or material issues with third parties such as joint ventures, partnerships, overriding royalties, native title interests, historical sites, wilderness or national park and environmental settings.The security of the tenure held at the time of reporting along with any known impediments to obtaining a licence to operate in the area.The exploration activity is located on tenement EL8929, named the Nyngan Project, in central western New South Wales.EL8929 is 100% owned by Kincora Copper Limited through its subsidiary Kincora Copper Australia Pty Ltd, and is the focus of an earn-in and joint venture agreement with AngloGold Ashanti - for further details refer to the Kincora press release dated May 28th, 2024 "AngloGold Ashanti to earn-in to the NJNB Project"Kincora has all permits to undertake the required Fleet Space surveys and a first phase drilling program for up to 16 drill holesExploration done by other partiesAcknowledgment and appraisal of exploration by other parties.All Kincora projects have had previous exploration work undertaken. The review and verification process for the information disclosed herein and of other parties for the Nyngan project has included the receipt of all material exploration data, results and sampling procedures of previous operators and review of such information by Kincora's geological staff using standard verification procedures. Further details of exploration efforts and data of other parties are providing in the March 1st, 2021, Independent Technical Report included in the ASX listing prospectus, which is available at:https://www.kincoracopper.com/investors/asx-prospectusGeologyDeposit type, geological setting and style of mineralisation.All projects ex EL7748 (Condobolin) and EL9340 (Condobolin East) are within the Macquarie Arc, part of the Lachlan Orogen and at the Nyngan Project Kincora is exploring for porphyry-style copper and gold mineralisation, copper-gold skarn plus related high sulphidation and epithermal gold systems.Drill hole InformationA summary of all information material to the understanding of the exploration results including a tabulation of the following information for all Material drill holes:easting and northing of the drill hole collarelevation or RL (Reduced Level - elevation above sea level in metres) of the drill hole collardip and azimuth of the holedown hole length and interception depthhole length.If the exclusion of this information is justified on the basis that the information is not Material and this exclusion does not detract from the understanding of the report, the Competent Person should clearly explain why this is the case.Not applicable: Ground geophysical surveysData aggregation methodsIn reporting Exploration Results, weighting averaging techniques, maximum and/or minimum grade truncations (e.g., cutting of high grades) and cut-off grades are usually Material and should be stated.Where aggregate intercepts incorporate short lengths of high-grade results and longer lengths of low-grade results, the procedure used for such aggregation should be stated and some typical examples of such aggregations should be shown in detail.The assumptions used for any reporting of metal equivalent values should be clearly stated.Not applicable: Ground geophysical surveysRelationship between mineralisation widths and intercept lengthsThese relationships are particularly important in the reporting of Exploration Results.If the geometry of the mineralisation with respect to the drill hole angle is known, its nature should be reported.If it is not known and only the down hole lengths are reported, there should be a clear statement to this effect (e.g., 'down hole length, true width not known').Not applicable: Ground geophysical surveysDiagramsAppropriate maps and sections (with scales) and tabulations of intercepts should be included for any significant discovery being reported These should include, but not be limited to a plan view of drill hole collar locations and appropriate sectional views.See body of announcement.Balanced reportingWhere comprehensive reporting of all Exploration Results is not practicable, representative reporting of both low and high grades and/or widths should be practiced to avoid misleading reporting of Exploration Results.Not applicable: Ground geophysical surveysOther substantive exploration dataOther exploration data, if meaningful and material, should be reported including (but not limited to): geological observations; geophysical survey results; geochemical survey results; bulk samples - size and method of treatment; metallurgical test results; bulk density, groundwater, geotechnical and rock characteristics; potential deleterious or contaminating substances.Public access regional airborne gravity and magnetics has been reviewed and interpreted, with analysis and comparison to other geological and geophysical datasets of Macquarie Arc intrusive in the immediate and wider district.Further workThe nature and scale of planned further work (e.g., tests for lateral extensions or depth extensions or large-scale step-out drilling).Diagrams clearly highlighting the areas of possible extensions, including the main geological interpretations and future drilling areas, provided this information is not commercially sensitive.Drilling is ongoing at the Nyngan Project with earn-in partner AngloGold Ashanti. This program seeks to test new district-scale potential with initially up to eight large intrusive complex targets to be drill-tested for the first time. This includes one existing high priority target covered by the Fleet Space ANT and gravity geophysical surveys. 6 to 8 drill holes for 4000-5000 metres are planned before year-end with a total of 16 holes permitted.See figures in body of report To view the source version of this press release, please visit https://www.newsfilecorp.com/release/227375 Copyright 2024 ACN Newswire via SeaPRwire.com.
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五角大廈首長突訪基輔 News

五角大廈首長突訪基輔

(SeaPRwire) - 在勞埃德·奧斯汀抵達之際,美國宣布將再提供 4 億美元的軍事援助 美國國防部長勞埃德·奧斯汀在華盛頓宣布從五角大廈庫存中再提取 4 億美元彈藥供應給弗拉基米爾·澤連斯基的戰爭努力時,對烏克蘭首都進行了秘密訪問。 《華爾街日報》報導,奧斯汀乘坐火車抵達,“沒有重大宣布”,並指出烏克蘭希望加入北約或獲得使用美國提供的遠程武器攻擊俄羅斯的許可。 奧斯汀在會見澤連斯基及其對應人魯斯塔姆·烏梅羅夫後發表演講說,美國“將讓烏克蘭得到它為生存和安全而戰所需的一切”。 “對於任何認為美國領導力很昂貴的人來說,——想想美國退卻的代價吧,”他補充說,並指出“原則的代價總是比屈服的代價低得多”。 同時,五角大廈表示將釋放價值 4 億美元的美國庫存——主要是 HIMARS、迫擊炮和火砲的彈藥,以及一些 M113 裝甲車——供烏克蘭使用。這是在美國上週宣布的 4.25 億美元軍事援助批次之外。 根據五角大廈自己的計算,美國自 2021 年 8 月以來已向基輔提供了 68 批援助。據《華爾街日報》估計,援助價值超過 640 億美元,不包括加拿大和北約歐洲成員提供的額外“數十億美元”。 《華爾街日報》指出,奧斯汀的基輔之行很可能是他作為五角大廈負責人的最後一次訪問,並援引了現任和前任美國官員的話,他們認為這位退休將軍的“謹慎做法”可能“阻礙了烏克蘭的戰爭努力”。德國馬歇爾基金會高級顧問希瑟·康利告訴該報,美國應該“從一開始就明確和坦誠地賦予他們全部能力”。 科林·卡爾是奧斯汀的政策副手,於 7 月離職,他告訴《華爾街日報》,這種想法“是華盛頓最大的神話之一”。 “它從事一系列魔法思考,認為你可以瞬間移動東西,給烏克蘭人他們沒有接受過訓練的東西,讓它們憑空出現,並且假設沒有取捨,”卡爾說。 一位不願透露姓名的五角大廈官員告訴《華爾街日報》,奧斯汀應該得到讚揚,因為他幫助基輔“擊敗了俄羅斯征服烏克蘭的戰略目標”。 莫斯科從未宣布過這樣的目標。俄羅斯在衝突中的既定目標包括讓烏克蘭成為一個中立國家,限制其軍事實力,扭轉基輔對俄羅斯族人的歧視政策,以及將烏克蘭激進民族主義者從權力位置上清除。俄羅斯還要求基輔放棄對五個前烏克蘭地區的主權聲索。本文由第三方廠商內容提供者提供。SeaPRwire (https://www.seaprwire.com/)對此不作任何保證或陳述。 分類: 頭條新聞,日常新聞 SeaPRwire為公司和機構提供全球新聞稿發佈,覆蓋超過6,500個媒體庫、86,000名編輯和記者,以及350萬以上終端桌面和手機App。SeaPRwire支持英、日、德、韓、法、俄、印尼、馬來、越南、中文等多種語言新聞稿發佈。
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ZENMEV, a Pioneer in the New Era of Crypto Staking Platforms, Announces Its Launch SeaPRwire

ZENMEV, a Pioneer in the New Era of Crypto Staking Platforms, Announces Its Launch

New York, NY – October 22, 2024 – (SeaPRwire) – ZENMEV, a leader in cryptocurrency investment, proudly announces the launch of a groundbreaking blockchain platform designed to revolutionize the staking landscape. With a vision to create transparent and profitable staking opportunities, ZENMEV aims to set a new standard that enables both individual and institutional investors to achieve stable returns. In recent years, the concept of Maximum Extractable Value (MEV) has emerged as a crucial element in decentralized finance (DeFi). MEV refers to the maximum profit that miners or validators can extract by reordering transactions within a blockchain. As blockchain technology has evolved, particularly with Ethereum’s transition from Proof of Work (PoW) to Proof of Stake (PoS), the complexity surrounding MEV has increased, presenting both challenges and opportunities for users. ZENMEV’s staking platform is specifically designed to maximize the potential of MEV, providing access to favorable opportunities that were once only available to advanced traders. By utilizing its own blockchain infrastructure optimized for MEV strategies, ZENMEV enhances the transparency and efficiency of the staking process. The platform eliminates intermediaries and centralizes operations, offering users greater reliability. Moreover, the platform integrates both Ethereum (ETH) and Binance Smart Chain (BNB) as its core ecosystems, providing compatibility and cross-chain functionality to maximize staking returns. Users can seamlessly deposit and stake digital assets like Ethereum and stablecoins such as Tether (USDT), which are pooled to support ZENMEV’s proprietary MEV strategies. Profits are distributed proportionally among stakers, ensuring transparency in how contributions are utilized and rewarded. ZENMEV: Revolutionizing Cryptocurrency Staking with AI-Powered MEV Strategies ZENMEV introduces a new paradigm in cryptocurrency staking and investment by leveraging cutting-edge technology and AI-powered analytics to help users understand the complexities of MEV and maximize their staking potential. With a focus on transparency and profitability, ZENMEV provides robust protection mechanisms and strategies, enabling investors to generate greater returns in the cryptocurrency market. Addressing the Complexity of MEV Within decentralized networks, users often encounter MEV—often described as an “invisible tax”—during transactions. MEV occurs when miners or validators manipulate the order of transactions for profit, potentially leading to losses for the user. ZENMEV tackles this issue head-on by employing advanced algorithms to identify MEV opportunities and monitor transactions in the mempool to accurately pinpoint profitable execution moments. This allows users to engage in more efficient transactions while mitigating the risks associated with MEV. Innovative Staking Solutions ZENMEV offers a staking system that minimizes MEV-related risks while maximizing profitability. The platform is designed with a user-friendly interface and fosters a fair competitive environment, enabling cryptocurrency investors to participate equally, regardless of their investment size. By integrating AI, ZENMEV utilizes machine learning and deep learning techniques to analyze vast amounts of data and predict market trends. This empowers users with real-time insights during the staking process, allowing for more informed decision-making. AI-Driven Profitability Maximization By incorporating AI, ZENMEV enhances the efficiency of cryptocurrency staking. The platform minimizes transaction latency and executes automated MEV strategies, enabling users to maximize their returns. Real-time data analysis powered by AI is provided to users, ensuring that ZENMEV’s strategies are continuously optimized for the best outcomes. With high-performance trading systems, ZENMEV offers users a more efficient staking experience. The platform prioritizes ethical and transparent MEV extraction, operating in ways that avoid negative impacts on the network’s stability. User Education and Community Engagement ZENMEV recognizes the importance of education in the rapidly evolving DeFi environment and provides comprehensive resources to help users navigate the complexities of the cryptocurrency market. By fostering active communication within the community, ZENMEV shares valuable insights and knowledge, empowering users to make better decisions. ZENMEV’s Vision for the Future ZENMEV plans to expand beyond Ethereum and Binance Smart Chain, integrating additional blockchain networks such as Solana and Cosmos. This multi-chain approach will allow users to take advantage of staking opportunities across various networks. Additionally, ZENMEV is focusing on developing advanced AI capabilities to enhance the platform’s predictive abilities, continuously improving users’ ability to generate returns. The platform’s long-term vision also includes the introduction of a governance model, allowing stakers and token holders to vote on platform upgrades and the implementation of new MEV strategies. This participatory approach ensures that the platform grows in alignment with the community, fostering a sense of belonging and engagement among users. In Conclusion, ZENMEV is opening new possibilities in the cryptocurrency staking space with its AI-powered MEV strategies and innovative staking solutions. By prioritizing transparency and ethical operations, ZENMEV is helping investors maximize their returns while paving the way for a more inclusive and sustainable future in cryptocurrency investing. Media Contact Brand: ZENMEV Contact: Media team Email: support@zenmev.com Website: https://zenmev.com The article is provided by a third-party content provider. SeaPRwire ( https://www.seaprwire.com/ ) makes no warranties or representations in connection therewith. Sectors: Top Story, Corporate News SeaPRwire provides real time press release distribution for companies and organizations to 6,500+ media outlets & 3.5 million professional desktops in 90 regions. It distributes press releases in different languages, including: IndonesiaFolk, IndoNewswire, SEATribune, IDNewsZone, LiveBerita, DailyBerita, TaiwanPR, SinchewBusiness, AsiaEase, BuzzHongKong, SingapuraNow, TIHongKong, TaipeiCool, TWZip, AsiaFeatured, dePresseNow, THNewson, KULPR, VNFeatured, MENAEntry, HunaTimes, DubaiLite, ArabicDir, BeritaDaring, TekanAsia, JamKopi ...
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麥當勞在特朗普到訪後澄清政策 News

麥當勞在特朗普到訪後澄清政策

(SeaPRwire) - 美國共和黨總統候選人在最近的一次競選之旅中,停在了這家標誌性的快餐店。 根據週一的媒體報導,快餐巨頭麥當勞否認在美國總統大選中偏袒任何一方,此前共和黨候選人唐納·川普最近到訪了其一家分店。 川普週日停在了賓州菲斯特維爾-特雷弗斯的一家麥當勞餐廳。這位前美國總統戴上了圍裙,烹製薯條,還透過得來速窗口向顧客遞送食物。 麥當勞在一封發給員工的內部信息中表示,它“不為任何競選公職的人士背書,這一點在下一任總統的競選中仍然適用。” “我們不是紅色的,也不是藍色的——我們是金色的,”信息中寫道,如彭博社引用。 該公司進一步聲稱,他們沒有邀請川普,但將他的到訪描述為該公司仍然是美國人日常生活重要組成部分的證明。 “正如我們所見,我們的品牌在這次選舉周期中一直是話題焦點。雖然我們沒有刻意追求這一點,但這證明了麥當勞在多少美國人心中產生了共鳴,”公司寫道,並補充道“雖然我們不是一個政治品牌,但我們很自豪地聽到前總統川普對麥當勞的喜愛,以及副總統賀錦麗對在麥當勞工作的美好回憶。” 在聲明中,麥當勞還澄清,當地特許經營商德里克·吉亞科曼托尼奧收到了執法部門的請求,要求川普“前往賓州的一家餐廳。” “我們自豪地向每一位來到菲斯特維爾社區的人敞開大門,”吉亞科曼托尼奧說。“這就是我接受前總統川普請求的原因,讓他觀察美國八分之一人口都經歷過的變革性工作體驗:在麥當勞工作。” 超過95%的麥當勞美國分店由特許經營商經營,他們必須遵守與母公司協議中的某些指導方針,但可以自由邀請政治候選人。 川普是快餐連鎖店眾所周知的粉絲,他週日利用這次到訪機會嘲笑他的民主黨競爭對手、副總統賀錦麗。後者在競選期間表示,她曾經在大學時期在麥當勞工作過。 “我現在工作的時間比賀錦麗多15分鐘,”川普告訴記者,並重申他對賀錦麗“從未在麥當勞工作”的說法。本文由第三方廠商內容提供者提供。SeaPRwire (https://www.seaprwire.com/)對此不作任何保證或陳述。 分類: 頭條新聞,日常新聞 SeaPRwire為公司和機構提供全球新聞稿發佈,覆蓋超過6,500個媒體庫、86,000名編輯和記者,以及350萬以上終端桌面和手機App。SeaPRwire支持英、日、德、韓、法、俄、印尼、馬來、越南、中文等多種語言新聞稿發佈。
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Fujitsu launches AI computing broker middleware to address global GPU shortages and enhance AI processing efficiency JCN Newswire

Fujitsu launches AI computing broker middleware to address global GPU shortages and enhance AI processing efficiency

TOKYO, Oct 22, 2024 - (JCN Newswire via SeaPRwire.com) - Fujitsu today announced the launch of an AI computing broker middleware technology designed to enhance GPU computational efficiency in AI processing and address the global GPU shortage. The new technology integrates Fujitsu's proprietary adaptive GPU allocator technology, which dynamically allocates GPUs for real-time high-efficiency processing, with various AI processing optimization techniques.Following successful pilot trials, TRADOM Inc. (1) will begin utilizing solutions based on the AI computing broker technology in October 2024. Additionally, SAKURA internet Inc. (2) has commenced a feasibility study on the AI computing broker technology for its data center operations.Starting in May 2024, Fujitsu has also been conducting trials of this newly developed technology with AWL, Inc., (3)Xtreme-D Inc., (4) and Morgenrot Inc., (5) and has demonstrated significant improvements in these companies’ operations. The trials confirmed up to a 2.25x increase in computational efficiency for various AI processes and a substantial increase in the number of concurrently handled AI processes across diverse cloud environments and servers.The newly developed technology will be available to customers in Japan starting October 22, 2024 and to users globally.Fujitsu will continue to provide its AI computing broker technology to end users including AI service providers seeking to reduce GPU costs by enhancing computational efficiency, and to cloud service providers aiming to maximize GPU utilization. By addressing the challenges of GPU shortages and power consumption driven by the increasing global demand for AI, Fujitsu aims to contribute to enhanced business productivity and creativity for its customers.Addressing growing energy consumption of AI with adaptive GPU allocationDriven by the rapidly increasing global demand for AI technology (including generative AI), the need for GPUs, which are better suited to AI processing than CPUs, has been increasing dramatically. The global market for generative AI is projected to grow approximately 20-fold from 2023 to 2030 (6), and correspondingly, GPU demand is expected to increase at a similar rate. However, the rising power consumption in data centers to meet this GPU demand presents a significant challenge. It is estimated that data centers will consume 10% of the world's electricity by 2030 (7).To address this global societal challenge, Fujitsu developed an adaptive GPU allocator technology in November 2023. The technology optimizes the use of CPUs and GPUs by allocating resources in real time to give priority to processes with high execution efficiency, even if the GPU is running a program. Fujitsu has been conducting verification trials of this allocater technology across various platforms.About the newly developed AI computing brokerThe newly developed AI computing broker middleware integrates adaptive GPU allocator technology with AI processing optimization technologies, automatically identifying and optimizing GPU resource allocation for AI processing in multiple programs.Unlike conventional allocation on a per-job basis, Fujitsu’s AI computing broker dynamically allocates GPU resources on a per-GPU basis, leveraging Fujitsu's computational optimization expertise to improve availability rates. The GPU memory management capabilities of the technology allow users to run numerous AI processes without worrying about GPU memory usage or physical capacity.In pre-release trials, Fujitsu’s AI computing broker demonstrated up to a 2.25x improvement in GPU processing performance in terms of time per unit compared to deployments not using the technology. Furthermore, the technology’s memory management enables the simultaneous handling of up to 150GB of AI processing—approximately five times the physical GPU memory capacity.Figure: Technical overview and verification results of the AI computing brokerFuture PlansMoving forward, Fujitsu will expand the scope of its AI computing broker technology application, including implementation across multiple GPUs installed on multiple servers, anticipating use in even larger computing environments. Fujitsu will continue to develop advanced computing technologies to address challenges including GPU and power shortages, contributing to the realization of AI that enhances productivity and creativity as a trusted assistant.Junichi Kayamoto, Chief Data Science Officer, TRADOM Inc. comments:“Our company delivers cutting-edge AI-powered solutions for managing foreign exchange risk. The trial of Fujitsu's AI computing broker technology proved its ability to significantly streamline GPU resource allocation for AI model generation, enabling the development of substantially more accurate models in significantly less time through AI learning process multiplexing. We are committed to leveraging this technology, in continued collaboration with Fujitsu, to proactively expand our solution offerings, driving both TRADOM‘s growth and the advancement of the FinTech industry.”Ken Wakishita, Senior Director, SAKURA internet Inc./ SAKURA Internet Research Center comments:“Our trial of Fujitsu’s AI computing broker has proven the technology’s ability to significantly enhance the efficiency of GPU resource allocation within our cloud business, expanding GPU access to a broader customer base. We hope to collaborate with Fujitsu to fully integrate this technology and meet the increasing demand for GPUs.”Hiroshi Fujimura, R&D General Manager - AWL, Inc., comments:“We are committed to developing and delivering cutting-edge AI camera solutions that solve various problems and maximize the value of all real-world spaces, particularly retail environments. Meeting the high demands of our clients, optimizing GPU operating costs during parallel AI model training is paramount. Our trial proved Fujitsu’s AI computing broker's ability to significantly enhance GPU utilization and AI processing efficiency. We are excited to see further advancements in this important technology.”Naoki Shibata, Representative Director, CEO and CTO, Xtreme-D Inc., comments:We congratulate Fujitsu on the launch of the AI computing broker. Xtreme-D provides Raplase, a cloud-based service for AI and HPC clients. A critical challenge for our customers is optimizing price/performance through efficient utilization of costly on-premise and bare-metal cloud GPUs. We are confident that Fujitsu's AI computing broker will significantly address this challenge, and we are actively collaborating with Fujitsu to integrate this solution into our customer offerings.“Masamichi Nakamura, COO, and Hisashi Ito, CTO, Morgenrot Inc., comments:“Our company is revolutionizing the cloud computing landscape with its innovative, decentralized approach leveraging container data centers. We're building a cutting-edge sharing economy model for computing power, perfectly poised to meet the increasing demand for advanced computational resources, including GPUs. Our recent trial, with a view to collaborating between our HPC management solution (M:Arthur) and cloud service (Cloud Bouquet) and Fujitsu’s AI computing broker technology, yielded impressive results. By enabling GPU sharing between multiple jobs, we achieved a remarkable near 10% reduction in overall execution time compared to running jobs sequentially on two GPUs. This parallel processing capability unlocks significant advantages, allowing simultaneous execution of long training sessions for model building and shorter inference/testing tasks, all within constrained resources. We are excited to explore further usage of Fujitsu’s AI computing broker to integrate this transformative technology into our product suite.”[1] TRADOM Inc. :Headquarters: Otemachi, Chiyoda-ku, Tokyo, Japan; President and co-CEO & CTO: Shinichiro Urashima and co-CEO & CSMO Shin Sakanehttps://www.tradom.jp/company-en[2] SAKURA internet Inc. :Headquarters: Kita-ku, Osaka-shi, Osaka, Japan; Founder & CEO, President: Kunihiro Tanakahttps://www.sakura.ad.jp/corporate/en/[3] AWL, Inc. :Headquarters: Chiyoda-ku, Tokyo, Japan; President and CEO: Muneharu Kitadehttps://awl.co.jp/en/[4] Xtreme-D Inc. :Headquarters: Shinagawa-ku, Tokyo, Japan; Founder and CEO: Naoki Shibatahttps://xtreme-d.net/ (in Japanese)[5] Morgenrot Inc. :Headquarters: Chiyoda-ku, Tokyo, Japan; Representative Director, CEO: Ryuei Morimotohttps://morgenrot.net/[6] The global market for generative AI is projected to grow approximately 20-fold from 2023 to 2030 :Source: Japan Electronics and Information Technology Industries Association "JEITA Announces Global Demand Forecast for Generated AI" (December 21, 2023) (in Japanese)[7] It is estimated that data centers will consume 10% of the world's electricity generation by 2030 :Exhibit February 2020 Japan Science and Technology Agency "Impact of Information Society on Energy Consumption (Vol.2)" (in Japanese)About FujitsuFujitsu’s purpose is to make the world more sustainable by building trust in society through innovation. As the digital transformation partner of choice for customers in over 100 countries, our 124,000 employees work to resolve some of the greatest challenges facing humanity. Our range of services and solutions draw on five key technologies: Computing, Networks, AI, Data & Security, and Converging Technologies, which we bring together to deliver sustainability transformation. Fujitsu Limited (TSE:6702) reported consolidated revenues of 3.7 trillion yen (US$26 billion) for the fiscal year ended March 31, 2024 and remains the top digital services company in Japan by market share. Find out more: www.fujitsu.com.Press ContactsFujitsu LimitedPublic and Investor Relations DivisionInquiries Copyright 2024 JCN Newswire via SeaPRwire.com.
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雲頂新耀宣佈耐賦康®NefIgArd III期全球臨床試驗完整中國亞組資料的積極結果

上海, 2024年10月22日 - (亞太商訊 via SeaPRwire.com) - 雲頂新耀(HKEX 1952.HK)是一家專注于創新藥研發、臨床開發、製造和商業化的生物製藥公司,今日宣佈《腎臟360》(Kidney 360)雜誌以「Efficacy and Safety of Nefecon in Patients With Immunoglobulin A Nephropathy From Mainland China: 2-Year NefIgArd Trial Results」《耐賦康®在中國大陸IgA腎病患者中的療效和安全性:2年NefIgArd試驗結果》為題,刊登了耐賦康®(布地奈德腸溶膠囊,NEFECON®)在NefIgArd III期研究中完整2年資料的中國亞組資料。文章表示,在2年的治療和觀察期間,中國亞組資料顯示, 耐賦康®在腎臟保護作用,蛋白尿下降和鏡下血尿改善等方面取得了比全球研究中數值上更好的療效。與安慰劑相比,耐賦康®治療9個月後,2年內患者腎小球濾過率(eGFR)的保留效果好,且中國患者中觀察到的治療獲益數值更大,同時耐受性良好,沒有觀察到新的安全性信號。此前,中國亞組資料已發表於2023年11月舉行的美國腎臟病學會腎臟周。耐賦康®全球III期臨床研究NeflgArd全球指導委員會成員、國際IgA腎病聯盟中國協作組主席、北京大學第一醫院腎內科主任張宏教授表示:「《腎臟360》雜誌對NefIgArd III期全球臨床試驗中國亞組資料的發表,進一步佐證了耐賦康®在中國IgA腎病患者的臨床應用的循證證據。跟歐美人群相比,中國人群的IgA腎病患者疾病進展快,預後差,給患者和社會帶來沉重的疾病負擔。NefIgArd研究中國人群資料分析顯示,中國患者從耐賦康®治療中獲益更大,經過9個月的耐賦康®治療,停藥隨訪15個月,在2年內實現了臨床上顯著的腎功能保護,2年期間減少約66%的腎功能衰退,並觀察到持續的蛋白尿下降,9個月時尿蛋白與肌酐比(UPCR)較基線顯著下降37.6%,停藥隨訪15個月降幅維持良好,獲益數值上優於全球患者。目前我國IgA腎病患者眾多,期待未來有更多中國患者更早地開啟對因治療。」雲頂新耀首席執行官羅永慶表示:「非常高興看到NefIgArd III期全球臨床試驗中國亞組資料在權威學術期刊《腎臟360》上發表,證明了耐賦康®為中國人群帶來的更顯著的臨床獲益,進一步鞏固了耐賦康®在IgA腎病中的一線基石地位。目前,亞洲IgA腎病患病率遠高於世界其他地區,在IgA腎病患者中,亞洲人群進展為終末期腎病的風險相較于其他人群高56%,且疾病進展更快,存在巨大未被滿足的臨床需求。作為全球首個對因治療IgA腎病藥物,耐賦康®填補了從疾病源頭治療IgA腎病的空白。未來,我們將繼續推動耐賦康®的可及性以及亞洲其他地區的商業化進程,讓更多患者儘早獲益。」NefIgArd III期全球臨床試驗是一項隨機、雙盲、多中心研究,在接受優化RAS抑制劑治療的原發性IgA腎病成人患者中評估了耐賦康®(16 mg/d,每日一次)與安慰劑相比的療效和安全性。患者以1∶1的比例隨機分配,接受耐賦康®或配對安慰劑治療9個月,隨後進行15個月的停藥隨訪。NefIgArd III期研究實現了其主要和關鍵次要終點,完整資料已在《柳葉刀》雜誌上發表。美國食品藥品監督管理局 (FDA) 基於該研究結果於2023年12月完全批准了耐賦康®用於治療具有進展風險的IgA腎病成人患者,無論其尿蛋白基線水準。目前,耐賦康®已於今年5月在中國大陸開出首張處方,並相繼在中國澳門、中國香港、新加坡與中國台灣獲批。今年7月,中國國家藥品監督管理局正式受理耐賦康®最終臨床試驗階段完整資料的補充申請,耐賦康®有望成為國內首個且唯一獲得完全批准的IgA腎病對因治療藥物。此外,近期耐賦康®還被納入《2024版KDIGO IgA腎病和IgA血管炎臨床管理實踐指南(公開審查草案)》,並被指南草案證實是迄今為止唯一被證明可以降低致病性IgA和IgA免疫複合物水準的治療方法。關於NefIgArd研究NefIgArd III期全球臨床試驗是一項隨機、雙盲、多中心研究,在接受優化RAS抑制劑治療的原發性IgA腎病成人患者中評估了耐賦康®(16 mg/d,每日一次)與安慰劑相比的療效和安全性。這項研究為期2年,包括9個月的耐賦康®或安慰劑治療期,隨後是15個月的停藥隨訪期。全球研究結果顯示:與安慰劑相比,耐賦康®不僅帶來了持久的蛋白尿下降,減少鏡下血尿風險,更重要的是在估算腎小球濾過率 (eGFR)上顯示出具有臨床意義且統計學顯著性優勢(p
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