Month: 2025-08

HONG KONG, Aug 14, 2025 - (ACN Newswire via SeaPRwire.com) - Everest Medicines (HKEX 1952.HK, “Everest”) today announced that the Taiwan Food and Drug Administration (TFDA) has officially accepted the New Drug Application (NDA) for VELSIPITY(R) (etrasimod) for the treatment of patients with moderately to severely active ulcerative colitis (UC).Building on prior approvals in Singapore, Hong Kong SAR, and Macao SAR, as well as NDA acceptance in South Korea, this marks significant progress in the commercialization of VELSIPITY(R) across Asia. In December 2024, China’s National Medical Products Administration (NMPA) officially accepted the NDA for VELSIPITY(R).As a next-generation selective S1P receptor modulator, once-daily oral etrasimod demonstrates robust efficacy across multiple endpoints, including clinical remission, mucosal healing, endoscopic normalization and histological remission. Its clinical value has been robustly demonstrated in multiple global Phase III studies, including ELEVATE UC 52, ELEVATE UC 12 and ENLIGHT (ES101002) studies.“The NDA acceptance for VELSIPITY(R) in Taiwan, China marks another key progress in our commercialization pathway across Asia. As the number of UC patients in Asia continues to rise, there remains a significant unmet medical need. In China alone, there were approximately 800,000 patients with UC in 2024, and the number is estimated to reach 1 million by 2030. UC patients face the dual challenges of long-term treatment and maintaining quality of life." said Rogers Yongqing Luo, Chief Executive Officer of Everest Medicines. “This NDA acceptance underscores the clinical value of VELSIPITY(R). We remain committed to accelerating access to this innovative therapy in Mainland China and other Asian markets, supporting long-term disease management while enhancing patients’ quality of life.”The clinical part submitted to TFDA is mainly based on results from the ELEVATE UC Phase 3 registrational program (ELEVATE UC 52 and ELEVATE UC 12) and the ENLIGHT study (ES101002). The ELEVATE UC Phase 3 registrational program evaluated the safety and efficacy of etrasimod 2 mg once-daily on clinical remission in UC patients with moderately to severely active UC who had previously failed or were intolerant to at least one conventional, biologic, or Janus kinase (JAK) inhibitor therapy. Both studies achieved all primary and key secondary efficacy endpoints, with a favorable safety profile consistent with previous studies of etrasimod.The ENLIGHT study (ES101002) conducted by Everest, is a multicenter, randomized, double-blind and placebo-controlled Phase 3 trial of etrasimod in Asian countries, including China Mainland, China Taiwan and South Korea. This is the largest Phase 3 trial of moderately to severely active ulcerative colitis in Asia completed to date, with 340 eligible subjects randomized to treatment with etrasimod or placebo. The results demonstrate that treatment with etrasimod 2 mg resulted in a clinically meaningful and statistically significant improvement in the primary and all secondary endpoints. These findings provide strong evidence supporting the use of etrasimod in adult Asian patients with moderately to severely active ulcerative colitis.As Everest’s third commercialized product, VELSIPITY(R) has been officially approved by the Guangdong Provincial Medical Products Administration for adult patients with moderately to severely active UC. It is now available at medical institutions designated under the Connect Policy in the Greater Bay Area. Additionally, Everest has launched a factory construction project at its Jiashan site to support local production of VELSIPITY(R). Copyright 2025 ACN Newswire via SeaPRwire.com.

HONG KONG, Aug 14, 2025 - (ACN Newswire via SeaPRwire.com) - Yuexiu Real Estate Investment Trust ("Yuexiu REIT", together with Yuexiu REIT Asset Management Limited, collectively known as the “REIT”; stock code: 405) announced its interim results for the six months ended 30 June 2025.Yuexiu REIT Management Team: Chairman and Non-Executive Director Mr. JIANG Guoxiong (center), Executive Director and Chief Executive Officer Ms. OU Haijing (left), and Chief Financial Officer Mr. KWAN Chi Fai (right)2025 Interim Results Highlights:- Overall operation was stable, with total revenue of RMB966 million (corresponding period of 2024: RMB1,034 million).- As at 30 June 2025, the overall occupancy rate of the properties was 82.2% (corresponding period of 2024: 84.0%).- The average financing cost was 3.33%, representing a decrease of 83 basis points from the beginning of the year. Excluding exchange loss, financing expenses decreased by 13.5% year-on-year.- Interim distribution of approximately RMB0.0333 per unit, equivalent to approximately HK$0.0366. This represents an annualized distribution yield of 8.42%.Guangzhou International Finance Center (GZIFC):- Operating revenue of the GZIFC complex was RMB486 million, accounting for 50.3% of the REIT’s total revenue.- Its office building introduced a Fortune Global 500 company, the occupancy rate was 82.6%, and the renewal rate was 70%.- GZIFC Shopping Mall had a high occupancy rate of 96.4% during the period.- Four Seasons Hotel Guangzhou achieved a 1.1-percentage-point year-on-year increase in average occupancy rate with record room revenue for the period, while Ascott Serviced Apartments GZIFC recorded a 1.8-percentage-point rise in average occupancy and similarly reached historic highs in revenue.Yuexiu Financial Tower:- Yuexiu Financial Tower recorded operating revenue of approximately RMB165 million, representing 17.1% of the REIT’s total revenue. The occupancy rate was 82.1%.- The tenant structure continued to improve, with new introduction of quality tenants such as a Fortune Global 500 company and a futures company with a market value exceeding RMB10 billion.Proactive Management of Financing Risk and Effective Stabilization of Financing Cost- With regard to the short-term loan of RMB530 million and the 5-year syndicated loan of HK$2.1 billion, both due in the first half of 2025, and other loans which are due within the year, the Manager in the first half of 2025 renewed the short-term loan of RMB530 million, obtained offshore loan of RMB1.7 billion and issued dim sum bonds of RMB1 billion for the refinancing and early repayment of the maturing loans so as to ensure effective monitor on the liquidity risk.- The Manager introduced a total of RMB3.23 billion in loans in the first half of 2025 to refinance offshore HKD floating rate loans, taking advantage of the relatively low-cost of RMB financing to proactively adjust the financing structure, thereby minimizing the impact of the interest rate market. At the end of the first half of 2025, the financing interest rate exposure of Yuexiu REIT was approximately 14%, narrowing by 12 percentage points from 26% at the beginning of the year; the average financing cost was 3.33%, representing a decrease of 83 basis points from 4.16% at the beginning of the year; the average interest payment rate for the first half of the year was 3.92%, representing a year-on-year decrease of 64 basis points. Excluding the exchange loss, the finance expenses amounted to approximately RMB402 million, representing a year-on-year decrease of 13.5%.- As at the end of June 2025, Yuexiu REIT had RMB financing of approximately RMB14,795 million, accounting for 72% of total financing (corresponding period of 2024: RMB financing of approximately RMB8,404 million, accounting for 41% of total financing).Mr. JIANG Guoxiong, Chairman and Non-Executive Director of Yuexiu REIT, said, "In the first half of 2025, against the backdrop of global trade volatility and slowing economic growth, China's GDP achieved steady growth of 5.3%, yet corporate expansion remained cautious and slow; retail consumption was weak, and average daily rate of hotel and apartment was under pressure. In order to effectively deal with the headwinds in the industry, we took strategic actions to secure market share by renewing leases in advance, investing in asset appreciation projects to enhance product competitiveness, and effectively stabilizing the fundamentals of operations, which effectively supported the revenue of Yuexiu REIT for the Interim Period. Meanwhile, lower financing cost is beneficial to the distributions.”Guangzhou International Finance Center (GZIFC)GZIFC achieved positive growth in both customer flow and conversion rates through product enhancement and operational optimisation, with a newly contracted area of 13,133 sq.m.. The newly launched 4,235 sq.m. of furnished units recorded an absorption cycle of only about 19 days, with an absorption rate close to 90%. Quality tenants introduced include a Fortune Global 500 company, a leading global shipping company, and a renowned Internet-based culture, sports and entertainment company, taking up more than 2,200 sq.m. in aggregate. In addition, the project recorded a renewed leasing area of 9,099 sq.m. and a renewal rate of 70%, retaining quality tenants including two Fortune Global 500 companies and a foreign consulate. GZIFC was selected as one of the Top 30 companies in the “Performance Index - 2025 Commercial Property Operation Performance” by Guandian.GZIFC Shopping Mall actively created digitalized consumption scenarios, advanced the pilot implementation of the local lifestyle platform “YueXiu Club”, which now covers 12 merchants, while attracting customers through multiple channels such as Dianping and UnionPay QuickPass platforms. Newly contracted area and renewed leasing area totaled 5,734 sq.m., with a renewal rate of 97% and the occupancy rate of 96.4%. During the period, it was announced that China Duty Free Group (CDFG) will set up a store in GZIFC Shopping Mall, which will be the first and currently the only downtown duty-free store in Guangzhou and is expected to open in the third quarter.Room revenue of Four Seasons Hotel Guangzhou and revunue of Ascott Serviced Apartments GZIFC reached a record high for the period, respectively. During the period, the average occupancy rate of Four Seasons Hotel Guangzhou reached 80.1%, representing a year-on-year increase of 1.1 percentage points. The average room rate was RMB2,201, similar to the same period last year. The revenue per available room (RevPAR) was RMB1,762, representing a year-on-year increase of 0.7%. The RevPAR competitive index was 111.7, maintaining a leading market position among luxury hotel competitors. The average occupancy rate of Ascott Serviced Apartments GZIFC reached 92.3%, representing a year-on-year increase of 1.8 percentage point and 9.7 percentage points higher than that of serviced apartment competitors. The average room rate was RMB1,128, similar to the same period last year. The RevPAR was RMB1,041, representing a year-on-year growth of 1.5%. The RevPAR competitive index reached 120.0.Yuexiu Financial TowerDuring the period, Yuexiu Financial Tower recorded a newly contracted area of 7,448 sq.m., including a total of 1,500 sq.m. further took up by seven existing tenants looking for expanded area. 7,089 sq.m. of furnished units were launched, with with an absorption cycle of approximately 38 days and an absorption rate of more than 65%. Quality tenants newly introduced include a Fortune Global 500 company and a futures company with a market value of over RMB10 billion. As certain tenants relocated to their own properties, the project recorded a renewed leasing area of 10,303 sq.m. and a renewal rate of 42%, retaining quality tenants with large leasing areas, including Deloitte, one of the Big Four international accounting firms, and a leading integrated asset management company in China.White Horse BuildingDuring the period, White Horse Building introduced supply chain resources from the Pearl River Delta and recorded a newly contracted area of 3,273 sq.m., with full occupancy on the 1st floor. In the first half of 2025, it welcomed a total of 165 procurement delegations, along with nearly 5,000 purchaser visits, including 23 foreign delegations from France, Vietnam and other countries, and facilitated procurement deals worth RMB140 million. By taking advantage of exhibitions such as the Greater Bay Area International Women’s Wear Expo and the Canton Fair, White Horse Building facilitated tenant transactions. It also successfully launched the cross-border e-commerce platform “White Horse Global E-Channel” and set up a series of courses titled “White Horse Business School Marketing Empowerment Camp” to activate new momentum for tenants’ digital operations.Fortune PlazaDuring the period, the project recorded a newly contracted area of 2,354 sq.m., and introduced quality tenants including several healthcare and elderly care subsidiaries of a Fortune Global 500 integrated financial group. The project recorded a renewed leasing area of 2,924 sq.m. and a renewal rate of 76%, retaining quality tenants including a Fortune Global 500 company, and flexibly adjusted units to match their demand for cost efficiency.City Development PlazaDuring the period, the project recorded a newly contracted area of 7,585 sq.m. and introduced a beauty technology company to enhance the ambience of healthcare business in the building. Retention plans were formulated in light of tenants’ pursuit of cost efficiency, aimed at optimizing product standards to meet tenant needs. The project recorded a renewed leasing area of 2,090 sq.m. and a renewal rate of 68%, retaining tenants including the Guangzhou office of a globally-renowned Contract Research Organisation (CRO).Victory PlazaDuring the period, its anchor tenant, Uniqlo, continued to play a flagship role by launching its C-series products, and hosted the first “A Better Life” campaign of Uniqlo in China, along with gigantic Pokémon installations and A Better Life Music Event, from 28 March to 6 April. Customer flow reached a quarterly peak during the events, driving a 7% year-on-year sales growth in April, and contributing to a 0.3% year-on-year sales growth during the Interim Period. By collaborating with tenants engaged in catering services to capitalize on increased sales with the surge in customer flow, the project drove a year-on-year increase of 0.6% in overall sales during the Interim Period.Shanghai Yue Xiu TowerDuring the period, the project recorded a renewed leasing area of 3,798 sq.m., with a renewal rate of 39%, while securing a newly contracted area of 3,933 sq.m., efficiently making up for the units surrendering ahead of lease expiry. By replacing the energy-saving light tubes in the carpark spaces to enhance brightness, the project enhanced both energy efficiency and service standards, thereby improving tenant satisfaction. As at the end of the Interim Period, the occupancy rate of Shanghai Yue Xiu Tower was 87.2%, representing a year-on-year increase of 2.6 percentage points.Wuhan PropertiesDuring the period, Wuhan Yuexiu Fortune Centre recorded a newly contracted area of 12,395 sq.m., and introduced quality tenants including a member of a leading global automobile group and a diversified professional services company. In addition, it recorded a renewed leasing area of 10,884 sq.m. and a renewal rate of 81%, retaining quality tenants with large leasing areas, including a Fortune Global 500 state-owned enterprise. The business solicitation team optimized the customers’ property visiting experience through partial micro-renovation of units, soft furnishing upgrades and creation of AI model rooms to increase the conversion rate of customers.Starry Victoria Shopping Centre recorded a newly contracted area and renewed leasing area totalling 3,894 sq.m. with a renewal rate of 82% during the period. The project successfully introduced several popular food and beverage brands, including the internet-famous brand “Domino’s” on the 1st floor of Hall A, to attract more family customer groups. The project tapped into nighttime consumption by leveraging the unique appeal of “Joy Garden” on the 4th floor, continuously developing initiatives like “Riverside Starry Night” and “Midnight Diner” to stimulate new sales growth drivers.Hangzhou VictoryHangzhou Victory recorded a newly contracted area of 1,974 sq.m. and introduced a tenant to take up an entire floor during the period. In addition, it recorded a renewed leasing area of 6,083 sq.m. and a renewal rate of 64%, retaining quality tenants including a Fortune Global 500 construction engineering company and the Zhejiang branch of a state-owned enterprise in Shanxi Province.ProspectsThe market generally hopes for further interest rate cuts by the US Federal Reserve in the second half of 2025, though the path and extent remain uncertain. On the other hand, 2025 marks the concluding year of China’s “14th Five-Year Plan”, with policies prioritizing stability, including moderately accommodative monetary policies and “trade-in” consumption subsidy policies aimed at expanding domestic demand to stimulate market vitality. Consequently, the Manager expects the RMB interest rate to remain at a relatively low level. With the accelerated development of new quality productive forces and the advancement of supply-side reforms in China, the Manager expects that new industrial momentum will continue to emerge and business environment will improve. The highly anticipated 15th National Games is scheduled to open in Guangzhou in the second half of 2025, which is expected to boost consumption in shopping malls and demand for hotels and apartments.In the second half of 2025, the Manager will keep abreast of economic development trends and dynamically implement proactive, prudent and flexible leasing strategies, keenly seize potential opportunities, and continuously enhance the market competitiveness of asset portfolio. The Manager will continue to review and make reasonable adjustments to its financing structure depending on expectations of market developments, and introduce low-cost RMB financing through various RMB financing channels to seek more favorable financing costs to offset interest rate risks. Additionally, the Manager will carry out relevant asset appreciation projects as planned, with reasonable planning and phased renovation of the guest rooms at Four Seasons Hotel Guangzhou. By focusing on product enhancement, equipment renewal and safety guarantee, the Manager aims to achieve value preservation and appreciation of the properties and ensure the sound operation of the projects.About Yuexiu Real Estate Investment TrustYuexiu Real Estate Investment Trust ("Yuexiu REIT") was listed on the Hong Kong Stock Exchange of Hong Kong Limited on 21 December 2005 and is the first listed real estate investment trust only investing in properties in the People's Republic of China (the "PRC") in the world. The current property portfolio comprises ten high quality properties, namely Guangzhou International Finance Center, White Horse Building, Fortune Plaza, City Development Plaza, Victory Plaza, Yuexiu Financial Tower in Guangzhou, Yuexiu Tower in Shanghai, Wuhan Properties in Wuhan (including Wuhan Yuexiu Fortune Centre and Starry Victoria Shopping Centre), Victory Business Centre in Hangzhou and Yuexiu Building in Hong Kong, with a total area of ownership of approximately 1.184 million sq.m. All properties are located in the central business district of Guangzhou, Shanghai, Wuhan, Hangzhou and Hong Kong respectively. The categories of the properties include Grade-A offices, commercial complexes, retail business, hotel, serviced apartments and professional clothing market etc.For media enquiries:Strategic Financial Relations LimitedVicky LeeTel: +852 2864 4834Email:sprg_yx@sprg.com.hk Phoebe LeungTel: +852 2114 4172 Maggie ZhangTel: +852 2864 4903 Websitehttp://www.sprg.com.hk Copyright 2025 ACN Newswire via SeaPRwire.com.

HONG KONG, Aug 14, 2025 - (ACN Newswire via SeaPRwire.com) - Organised by the Hong Kong Trade Development Council (HKTDC), the five-day (14-18 August) Food Expo, Beauty & Wellness Expo and Home Delights Expo open to the public from today at the Hong Kong Convention and Exhibition Centre. The Food Expo PRO, held concurrently from 14 to 16 August, is open to trade buyers for the first two days and to the public and trade buyers on the final day. For the first time, the Hong Kong International Tea Fair will be open to both industry professionals and the public throughout its three-day duration (14-16 August). The International Conference of the Modernization of Chinese Medicine and Health Products (ICMCM), organised by the Modernized Chinese Medicine International Association (MCMIA) together with the HKTDC and ten scientific research institutions, also take place today and tomorrow (14-15 August).Due to Black Rainstorm Warning Signal, the opening of the fairs was delayed and the first session of the International Conference of the Modernization of Chinese Medicine was livestreamed.The Food Expo, Beauty & Wellness Expo, Home Delights Expo will extend the opening hours to 11pm on 15-17 August. The Food Expo PRO and Hong Kong International Tea Fair will remain open until 6pm today and tomorrow (14 to 15 August) and until 5pm on Saturday (16 August).Margaret Fong, Executive Director of the HKTDC, stated: "The 35th Food Expo celebrates an important milestone this year. The five-in-one mega event plays host to some 1,890 exhibitors from 36 countries and regions, serving as a one-stop destination and a vibrant marketplace for both trade professionals and consumers, where gourmet foods, fine teas, home essentials and beauty products can be found. Meanwhile, Food Expo PRO is dedicated to boosting Hong Kong’s status as a premier business hub for the food industry, not just in Mainland China, but across Asia and the globe. It empowers F&B professionals to explore new opportunities, forge valuable connections, and drive innovation.”Several exhibitors expressed that their special offers will remain unchanged. Among them, Phelix Pun from Ng Fung Hong Limited shared that staff arrived as usual this morning to prepare for the exhibition. They hope that, once the exhibition opens, it will continue to boost their business, with the planned special offers and interactive games proceeding as scheduled. They believe that citizens will continue to turn out enthusiastically to visit and shop.Five themed days create a quality living space1. Shall We Tea' (14 August)Today’s focus is on the variety of Chinese and Western tea beverages. This year, the Hong Kong International Tea Fair opens to the public for all three days for the first time, featuring pavilions from countries and regions such as Fujian, Hubei, Zhejiang, Kenya, and Sri Lanka to promote tea culture. Visitors can sample premium traditional teas like Bai Hao Yin Zhen (Silver Needle tea) (Booth: 5F-F01), one of the finest Chinese white teas, alongside wellness capsule tea (Booth: 5F-F05), and innovative new-style tea beverages from various regions (Booth: 5G-A21). The “Friends of Tea” Zone also offers tea-pairing snacks, tea-infused perfumes and more, offering a blend of traditional and modern tea culture experiences. Visitors can participate in various talks, including "The Legacy and Contemporary Dialogues of Chinese Tea Culture" and "The Beauty of Tea, Where Small Things Reveal Greatness”, as well as activities led by certified water sommeliers and tea masters exploring the diversity of water, decoding the secrets of tea flavours, and delving into the joy of tea appreciation.At the Food Expo, visitors can enjoy premium matcha and hojicha from Kyoto’s century-old Marukyu Koyamaen tea garden, blended with locally made fresh nut butter to create tea-flavoured gelato (Booth: 3B-E10). The Nin Jiom Tea Pairing Lucky Bag (Booth: 1C-A10) includes five functional teas with various health benefits. Additionally, Earl Grey tea infused with bergamot in drip-filter bags (Booth: 1D-A12) offers a refreshing citrus aroma.2. Flavours of Intangible Cultural Heritage (15 August)Despite its small size, Hong Kong boasts over 50 items on its intangible cultural heritage list related to food, showcasing its unique culinary culture. Exhibitors will present tea bags made with 100% Ceylon black tea, ready to brew for an effortless Hong Kong-style milk tea or Yuan Yang (Booth: 5F-F21). Additionally, there’s handmade shrimp paste from Hong Kong’s last remaining licensed salted fish and shrimp paste factory, capturing the authentic flavours of Hong Kong’s fishing village heritage (Booth: 1A-E02).The themed day features a series of activities centered on intangible cultural heritage. At the Home Delights Expo, master artisan Choi Wing-kei will share the story of preserving the traditional craft of floral plaque making, alongside demonstrations of Taiji and Wing Chun martial arts techniques, as well as introductions to the cultural significance of bamboo steamers and bamboo craftsmanship. The Food Expo will showcase demonstrations of making traditional Hakka Sau Fan. The Hong Kong International Tea Fair will host a seminar on "Chiu Chow Kung Fu Tea," exploring the distinctive tea culture of the Chaoshan region.3. Asian Delights (16 August)The day celebrates Asian cuisine and culture, featuring cooking demonstrations of Vietnamese dishes and molecular Thai cuisine, complemented by performances of the traditional Japanese shamisen, K-Pop dance, and a Thai yoga massage experience at the Beauty & Wellness Theatre, immerses visitors in the vibrant essence of Asia.At the Food Expo, the China National Agricultural Pavilion, organised by the Agricultural Trade Promotion Centre, the Ministry of Agriculture and Rural Affairs of Mainland China, will present a thousand agricultural and food products from 13 provinces, such as Korla fragrant pears, Xinjiang safflower seed oil, rainbow trout salmon, Guangdong lychee black tea, Lianzhou mustard greens, Hainan Wuzhishan large-leaf tea, Northeast black soil organic rice, and Yantai apples from the Qilu region.Visitors can explore a range of premium products at the Food Expo PRO. The 100% natural, hand-picked wild pine nut oil from Mongolia (Booth: 5C-G20) is a healthy choice for daily diets. A whisky from Soni Village in Nara Prefecture, renowned for its pristine spring water (Booth: 5B-B06), its smooth taste is perfect for a variety of uses, whether drinking neat, on the rocks, or mixed into a variety of cocktails. The spicy and crispy milk chocolate, made with Sichuan pepper oil, Espelette pepper, and almond paste filling (Booth: 3B-E04), would offer an unforgettable tasting experience.4. Body, Mind, and Soul (17 August)This year, the Beauty & Wellness Expo introduces the new "Scentsation” Zone, featuring over 20 brands showcasing a range of perfumes and aromatherapy products to nurture both mind and body. Making its debut at the expo, Lush (Booth: 3E-D08) presents its popular Deep Sleep Magnesium Massage Bar, designed to enhance sleep quality. In response to the growing opportunities in the silver economy, exhibitors are offering various products and services tailored for seniors. Mannings, participating in the Beauty & Wellness Expo for the first time, will feature a Smart Health Station, offering free health tests to help seniors select the best fit wellness products.The Food Expo, Beauty & Wellness Expo, and Home Delights Expo will host a series of seminars and activities, including hand massage workshops, discussions on the emerging trend of Hong Kong residents seeking cross-border medical care, towel exercise sessions, explorations of ergonomics and the latest treatments for various diseases, and diets to boost immunity. The performance stage will feature various sports demonstrations, such as taekwondo, street dance, and ballroom dancing.5. Taste HK (18 August)In recent years, organic farming has gained popularity, with growing demand for local produce. A cooking demonstration, co-organised by DRAGONS' DEN, the Vegetable Marketing Organization, and the Fish Marketing Organization at the Food Expo, will use local ingredients to create healthy and delicious home-cooked dishes. Additionally, the Home Delights Expo will feature notable products, including a glass-lined insulated handheld cup that won the 2024 Red Dot Product Design Award (Booth: 3F-D20), a water faucet awarded the 2023 Red Dot Design Award (Booth: 3F-B18), and a plug-and-play portable air conditioner that requires no exhaust duct (Booth: 3F-E25).At the Food Expo, visitors can savour a sparkling soda infused with lemon honey, salted plum, and ginger (Booth: 3B-A07), recreating classic Hong Kong flavors. A Kee Wah snack set paired with a cute panda backpack (Booth: 1E-C02) combines iconic treats. At the Food Expo PRO, traditional mooncakes developed by the Hong Kong Polytechnic University’s food team (Booth: 5C-C17) utilise exclusive AkkMore™ fungal fat-replacement technology, blending health with deliciousness.Exploring Halal Products, Coffee, and Food Science OpportunitiesThe 3rd Food Expo PRO and the 35th Food Expo have introduced a Halal food and beverage label since last year to assist exhibitors in expanding into the halal product market. This year, the two expos feature over 120 food suppliers showcasing halal products from around the world, a 20% increase compared to last year. The expo also strengthens collaborations with countries with thriving halal food markets. Group pavilions at the Food Expo PRO include ASEAN countries such as the Philippines, Thailand and Vietnam, enriching the variety of halal exhibits.The Food Expo PRO introduces a new "Coffee Zone" this year, showcasing coffee products, accessories, and machines from various origins. Yunnan Province, China’s leading coffee bean producer, is represented by several Pu’er City companies exhibiting Kunlu Mountain and Jinpaoshan roasted beans and other products. Another highlight, the "Food Science and Technology Zone”, presents alternative and future foods of interest to industry professionals. Today’s Food Tech Symposium explores the development of additive-free foods and clean labeling in Hong Kong. Exhibitors are also targeting the silver economy, showcasing innovative products such as soft-textured mooncakes and cognitive health supplements developed by local exhibitors.21 Prominent Speakers Discuss the Latest Developments in Chinese Medicine (14-15 August)The Modernized Chinese Medicine International Association, together with the HKTDC and ten scientific research institutions, provides industry professionals with the latest insights into Chinese medicine. Themed “The Latest Research Progress in the Prevention and Treatment of Tumors, Inflammation, and Cardiovascular and Cerebrovascular Diseases with Traditional Medicine”, the conference secures 21 prominent speakers, including experts from Hong Kong, Mainland China, and overseas, sharing innovative achievements and trends in the globalisation of Chinese medicine. Conducted in a hybrid format, the conference offers broader opportunities for interaction with speakers. Hong Kong-registered Chinese medicine practitioners can also earn Continuing Medical Education credits by attending the conference.Food Expo Celebrates 35th Edition with Exclusive OffersTo celebrate the 35th Food Expo, free admission tickets are available each day before noon, with 350 each at Halls 3FG and 5FG entrances and redeemable with the designated advertisement. Over 100 promotions are priced at HK$35 or discounted by 65% to tie in with the 35th Food Expo. The “Food Expo 35th Edition – Treasure Hunt” game engages visitors in Hall 3, where they can hunt for ‘treasure’, scan QR codes, answer questions correctly, and redeem gifts. Together with daily lucky draws, prizes are worth over HK$1 million, including kitchenware, furniture, beauty products, gourmet foods, health items; a lucky draw entry is granted for a single transaction of HK$300 or more. The “Smart Bidding” session allows visitors to bid on favourite items starting at 10% of their original price. Visit the “August Happy Buy” promotional website for flash sales and exclusive discounts.Snoopy is celebrating its 75th anniversary this year. The organiser invites visitors to participate in the “Snoopy Hide & Seek” activity at the Home Delights Expo, where they can snap photos with Snoopy and friends for a chance to win special prizes, joining in the festive celebration.Physical ticket sales are unavailable at the venue. E-tickets can be purchased in advance through AlipayHK, Alipay, 01 Space, 7-Eleven, Circle K, Octopus app, or The Club app, or at venue entrances using AlipayHK, Alipay, or Octopus. Discounted “Morning Admission” and “Evening Admission” are offered on select dates.Photo download: http://bit.ly/3Hzud7QThe five exhibitions, including the 35th Food Expo, the 9th Beauty & Wellness Expo, the 11th Home Delights Expo, the 3rd Food Expo PRO, the 16th Hong Kong International Tea Fair, and the International Conference of the Modernization of Chinese Medicine and Health Products, officially opened today.The Food Expo PRO introduces a new "Coffee Zone” this year, showcasing coffee products, accessories, and machines from various originsThe 3rd Food Expo PRO and the 35th Food Expo feature over 120 exhibitors showcasing a variety of halal foods, facilitating procurement for buyersThe Hong Kong International Tea Fair will be open to both industry professionals and the public for the first time, with several regional pavilions, showcasing unique tea cultures and premium tea products from various regions to the public and trade buyersThe Food Expo’s Gourmet Zone features seven themed areas, offering everything from exquisite main courses and craft beverages to delicious dessertsA new “Scentsation” Zone debuts at this year’s Beauty & Wellness Expo and features over 20 perfume and aromatherapy brands, using fragrances to balance the body and mindHome Delights Expo showcases a variety of home tech products, such as Towngas’ steam washing machine with smart stain treatmentOpening dates and times of the exhibitions:DateHKTDC Food Expo PROOpen to trade buyers only: 14-15 August (Thursday to Friday)Open to trade buyers and public: 16 August (Saturday)Hong Kong International Tea FairOpen to trade buyers and public: 14-16 August (Thursday to Saturday)HKTDC Food Expo, HKTDC Beauty & Wellness Expo, HKTDC Home Delights Expo14-18 August (Thursday to Monday)International Conference of the Modernization of Chinese Medicine and Health Products14-15 August (Thursday to Friday)TimeHKTDC Food Expo PRO, Hong Kong International Tea Fair14-15 August: 10:00 am to 6:00 pm16 August: 10:00 am to 5:00 pmHKTDC Food Expo, HKTDC Beauty & Wellness Expo, HKTDC Home Delights Expo14-17 August: 10:00 am to 10:00 pm18 August: 10:00 am to 6:00 pmVenueHong Kong Convention and Exhibition Centre, Wan ChaiAdmission- Food Expo Public Hall, Home Delights Expo, Beauty & Wellness Expo and Hong Kong International Tea Fair 2025 single ticket: HK$30 per person (ticketholders can pay a top-up fee of HK$10 for admission to the Gourmet Zone on the same day)- Food Expo Public Hall and Gourmet Zone, Home Delights Expo, Beauty & Wellness Expo and Hong Kong International Tea Fair 2025 combo tickets: HK$40 per person**HK$36 per person during the pre-sale period from 31 July to 13 August (tickets are available for pre-sale and walk-in at all 7-Eleven and Circle K convenience stores for HK$36 per person.)Remarks: Holders of 16 August single ticket & combo ticket can visit the Food Expo PRO- Morning admission tickets: Entry before noon on 14, 15 and 18 August, Thursday, Friday and Monday, to the Food Expo Public Hall, Home Delights Expo, Beauty & Wellness Expo and Hong Kong International Tea Fair on the same day: HK$10 (pay directly by AlipayHK, Alipay or Octopus card for admission at the hall entrances only)- Night admission tickets: Entry after 6:00 pm on 14 to 17 August, Thursday to Sunday, to the Food Expo Public Hall, Home Delights Expo, Beauty and Wellness Expo on the same day: HK$10 (pay directly by AlipayHK, Alipay or Octopus card for admission at the hall entrances only)- Concessionary price for persons with disabilities: HK$10 (top-up fee for the Gourmet Zone on the same day is HK$10) Note: Persons with disabilities need to present a “Registration Card for Persons with Disabilities”, issued by the Labour and Welfare Bureau (pay directly by AlipayHK, Alipay or Octopus card for admission at the hall entrances only)- Tourist tickets: HK$20 (HK$30 including admission to the Gourmet Zone)Note: Tourists need to present valid travel documents at the fairground to purchase tickets.Free admission is available for children aged three and under and senior citizens aged 65 or above (presenting valid age proof).TicketsE-tickets are available for sale at AlipayHK and Alipay, the 01 Space e-ticketing platform, all 7-11, Circle K convenience stores, Octopus app and The Club app.HKTDC Food Expo PROfoodexpopro.hktdc.comHKTDC Hong Kong International Tea Fairhkteafair.hktdc.comHKTDC Food Expohkfoodexpo.hktdc.comHKTDC Beauty & Wellness Expohkbeautyexpo.hktdc.comHKTDC Home Delights Expohomedelights.hktdc.comThe International Conference of the Modernization of Chinese Medicine (ICMCM)icmcm.hktdc.comAugust Happy Buy websiteecoupon.hktdc.com/food/Media EnquiriesOgilvy Public RelationsRex CheukTel : (852) 5618 9908Email : rex.cheuk@ogilvy.comLeanne PokTel : (852) 9379 9694 Email : leanne.pok@ogilvy.comDaisy LeungTel : (852) 9275 7704Email : daisy.leung@ogilvy.comHKTDC’s Communications and Public Affairs DepartmentStanley SoTel : (852) 2584 4049Email : stanley.hp.so@hktdc.orgSerena CheungTel : (852) 2584 4272Email : serena.hm.cheung@hktdc.orgClayton LauwTel : (852) 2584 4472Email : clayton.y.lauw@hktdc.orgMedia Room: http://mediaroom.hktdc.comAbout HKTDCThe Hong Kong Trade Development Council (HKTDC) is a statutory body established in 1966 to promote, assist and develop Hong Kong’s trade. With over 50 offices globally, including 13 in Mainland China, the HKTDC promotes Hong Kong as a two-way global investment and business hub. The HKTDC organises international exhibitions, conferences and business missions to create business opportunities for companies, particularly small and medium-sized enterprises (SMEs), in the mainland and international markets. The HKTDC also provides up-to-date market insights and product information via research reports and digital news channels. Copyright 2025 ACN Newswire via SeaPRwire.com.

HONG KONG, Aug 15, 2025 - (ACN Newswire via SeaPRwire.com) - Everest Medicines today announced that etrasimod (VELSIPITY(R)) has been included in the ACG Clinical Guideline Update: Ulcerative Colitis in Adults (the “Updated Guidelines”). Etrasimod, an S1P receptor modulator, is recommended for the induction of remission in patients with moderately to severely active UC and for continuation in the maintenance of remission, compared with no treatment after induction of remission. Both recommendations are strong, with a moderate quality of evidence.This milestone underscores the high level of recognition from an internationally respected clinical guideline for the therapeutic value of etrasimod and highlights its potential to address the significant unmet medical needs of UC patients, offering a new treatment option worldwide.The updated guidelines were developed by the American College of Gastroenterology (ACG) including the latest evidence from the past five years. They provide a comprehensive summary of new approaches and advances in the treatment and prevention of complications in UC, with the goal of offering clinicians standardized and evidence-based recommendations to better manage patients with varying degrees of disease severity.The updated guidelines note that, etrasimod is an oral, once-daily, selective sphingosine 1-phosphate (S1P) 1,4,5 receptor modulator for the treatment of moderately to severely active UC. The S1P 1 receptor modulation regulates the trafficking of specific lymphocyte subsets out of the lymph nodes, leaving fewer peripheral immune cells available to traffic to sites of inflammation.The updated guidelines also reference the Phase III ELEVATE UC clinical study for etrasimod (ELEVATE UC 52 and ELEVATE UC 12). Both studies achieved all primary and key secondary efficacy endpoints, with a favorable safety profile consistent with previous studies of etrasimod. Etrasimod has been included in the AGA Living Clinical Practice Guideline on the pharmacological management of moderate-to-severe UC as one of the higher-efficacy medications suggested for first-line use in advanced therapy-naïve patients.Prof. Wu Kaichun at the First Affiliated Hospital of AFMU who is the principal investigator for etrasimod’s Asia clinical trial said “The updated guidelines further emphasize that achieving endoscopic mucosal healing to enable sustained, steroid-free remission is a core treatment goal for patients. This is not only critical for the long-term and safe management of the disease but is also closely tied to improving patients’ quality of life. The strong recommendation of etrasimod for both induction and maintenance therapy in this population reflects the high level of recognition from an internationally authoritative medical authority.”“The inclusion of etrasimod in the 2025 American College of Gastroenterology (ACG) Clinical Guideline for Adult Ulcerative Colitis, with a strong recommendation, is a clear recognition of its clinical efficacy and favorable safety profile. Mucosal healing is a recognized treatment goal in both domestic and international clinical guidelines for UC. Achieving mucosal healing at an early stage can significantly reduce the risk of disease relapse, hospitalization, colectomy, and the development of colorectal cancer.” said Rogers Yongqing Luo, Chief Executive Officer of Everest Medicines. “In Asia, the number of UC patients continues to rise, while treatment options remain limited, highlighting an urgent need for innovative therapies that balance efficacy, safety, and convenience. In China alone, the UC patient population was estimated at approximately 800,000 in 2024 and is projected to reach 1 million by 2030, placing an increasing burden on the healthcare system.”As a key innovative asset in Everest Medicines’ autoimmune disease portfolio, etrasimod’s inclusion in the clinical guidelines underscores its global therapeutic potential as a new treatment option for UC patients across Asia, including in China. We remain committed to accelerating the regulatory approval process for etrasimod in Mainland China, South Korea, and other Asian markets to enhance patient access and help more individuals achieve higher-quality, longer-lasting disease remission.”As a core product of Everest Medicines, etrasimod has been approved in Singapore, Macao SAR, and Hong Kong SAR, and its NDA has been accepted in South Korea. In December 2024, China’s National Medical Products Administration (NMPA) officially accepted the NDA for VELSIPITY(R). As Everest’s third commercialized product, VELSIPITY(R) has been officially approved by the Guangdong Provincial Medical Products Administration for adult patients with moderately to severely active UC. It is now available at medical institutions designated under the Connect Policy in the Greater Bay Area. Additionally, Everest has launched a factory construction project at its Jiashan site to support local production of VELSIPITY(R). Copyright 2025 ACN Newswire via SeaPRwire.com.

Results Highlights:- Revenue reached US$83.6 million, a year-on-year increase of 5.9%.- Sales volume reached 919,000 units, of which 779,000 units were proprietary products, representing a year-on-year increase of 8.6%.- Profit attributable to owners of the company increased by 5.1% year-on-year to US$19.8 million.- Core operating profit amounted to US$15.1 million, an increase of 11.4% year-on-year.- The Board declared a special dividend of HK15 cents per share to mark the Group’s 25th anniversary.- The Group maintained a sound financial position with cash and bank balances of US$237.1 million as of June 30, 2025 to support potential acquisitions and the construction of new manufacturing facilities.- The Group’s high-quality products have gained widespread recognition worldwide, resulting in revenue growth of 14.0% in the APAC market, 17.0% in the EMEA market, and 20.0% in the US market.- The Group acquired a Taiwan-based distributor in the first half of the year. It also plans to establish direct sales teams in Belgium and the Netherlands in the second half of the year, further strengthening direct presence in APAC and EMEA markets.- Leveraging its global commercialization expertise and extensive distribution network, the Group established strategic partnerships with medical device peers, thereby diversifying its product portfolio and generating additional revenue through cross-selling opportunities.HONG KONG, Aug 15, 2025 - (ACN Newswire via SeaPRwire.com) - OrbusNeich Medical Group Holdings Limited (“OrbusNeich” or the “Group”; stock code: 6929), a multinational medical device company specializing in interventional devices for percutaneous coronary intervention (“PCI”) and percutaneous transluminal angioplasty (“PTA”) procedures, today announced its interim results for the six months ended June 30, 2025 (the “Period”), reporting growth in both revenue and net profit despite an uncertain macroeconomic landscape.The Group recorded revenue of US$83.6 million, up 5.9% over the previous year, driven by strong year-on-year growth in the US market, as well as continued contributions from emerging markets in APAC and EMEA. Core operating profit, being profit attributable to the owners of the Company excluding share-based compensation, net tax credit from deferred tax asset in relation to tax losses, and finance income/costs, amounted to US$15.1 million, up by 11.4% year-on-year. Profit attributable to the owners of the Company increased by 5.1% year-on-year to US$19.8 million. Basic earnings per share was US2.40 cents (first half of 2024: US2.28 cents).As of June 30, 2025, the Group maintained a strong financial position with cash and bank balances amounting to US$237.1 million. In light of the Group’s solid financial position and in celebration of the its 25th anniversary, the Board has resolved to declare a special dividend of HK15 cents per ordinary share, demonstrating the Group’s commitment to creating value for its Shareholders. Together with the final dividend of HK10 cents per share for the year ended December 31, 2024 paid on June 16, 2025, Shareholders will receive a total dividend of HK25 cents in 2025.Mr. David Chien, Chairman, Executive Director and Chief Executive Officer of OrbusNeich, said, “Over the past 25 years, we have continuously invested in innovation and global commercial capabilities, establishing OrbusNeich’s reputation and enabling us to navigate different economic cycles. Despite macroeconomic and geopolitical challenges in the first half of 2025, our global deployment proved resilient. Growth in the US market reflected strong demand for our high-quality products, while our extensive sales network successfully captured growth opportunities in the APAC and EMEA regions. We will continue to sharpen our competitive edge by enhancing brand value through our direct sales market presence, excellent sales support, commitment to innovation, and comprehensive PCI and PTA product portfolio, while advancing safer, more effective solutions for physicians and patients and delivering long-term returns to shareholders.”Global Sales Network and Partnerships Boost Revenue GrowthOrbusNeich has built a sales network spanning over 70 countries and regions, including direct teams in 13 locations and a global distributor network, which proven integral to capturing local opportunities and demand worldwide. APAC revenue rose by 14.0% year-on-year to US$27.3 million during the Period, fueled by growth in Indonesia and increasing adoption of Scoreflex TRIO in Singapore and Malaysia. EMEA revenue grew 17.0% to US$22.4 million, driven by strong proprietary balloon product sales in key direct markets (Germany, France, Spain) and distributor markets (the UK, Slovakia, Czech Republic). Despite tariff disruptions, US revenue increased by 20.0% to US$8.0 million, boosted by a notable surge in sales volume of standard and scoring coronary balloons and peripheral balloons, including the high-priced Scoreflex NC balloon. Revenue from the Japan and PRC markets was US$16.1 million and US$9.7 million, respectively.Leveraging its widely-recognized global commercialization expertise, the Group partnered with peers pursuing international expansion to enrich its product portfolio and drive additional revenue streams. Building on the successful collaboration with SonoScape Medical Corp. involving the distribution of intravascular ultrasound (“IVUS”) products in Hong Kong and Macau last year, the Group has entered into a sole and exclusive distribution agreement with this partner to distribute its IVUS products in Singapore and Malaysia. The collaboration now covers four additional direct European markets (France, Germany, Spain, Switzerland) and six other distributor markets across Europe.Performance-Led Innovation Fuels Market Distinction and Portfolio DiversityAs of June 30, 2025, OrbusNeich had obtained more than 250 granted patents and published patent applications in key jurisdictions worldwide, as well as over 55 approved products.During the Period, the Group made progress in terms of product registrations and clinical trials, including:- Sapphire 3’s US trial progressing smoothly, with patient enrollment set to finish in Q4 2025 to support FDA submission for the CTO indication, distinguishing it from other conventional semi-compliant balloons on the market;- Obtained CE Marks for JADE PLUS and Teleport Glide, PMDA approvals for Teleport Glide and Scoreflex QUAD, FDA approvals for the COREPASS Modular Microcatheter, and NMPA approval for the guiding catheter;- Submitted registration applications for Scoreflex TRIO, Sapphire ULTRA, Sapphire NC ULTRA, Sapphire NC 24, JADE PLUS, Teleport XT and Teleport Glide to the NMPA, and applications for the Vascuaid Aspiration Catheter and GCE Large Lumen to the PMDA.Regarding the Group’s robust product pipeline, the Sapphire PTX paclitaxel drug-coated balloon, in the coronary space, is set to begin clinical trials in Japan near the end of 2025. In the peripheral space, the JADE Score balloon is expected to be submitted for PMDA approval in 2026.The joint venture OrbusNeich P&F also made significant progress in the clinical trials of TricValve in the PRC, with the number of participating sites increased to accelerate patient enrollment. In addition, it has been actively promoting TricValve’s entry into hospitals in the Greater Bay Area (“GBA”) through the Hong Kong & Macau Registered Drugs and Medical Devices Access to GBA Program. The first commercial implantation of TricValve in the Mainland of China was completed in July 2025, marking the achievement of an important milestone.Multi-Region Production Bases Mitigate Evolving Geopolitical RisksAs of June 30, 2025, OrbusNeich’s aggregate annual production capacity was approximately 2.1 million balloons and stents, with production facilities in Shenzhen, the PRC; Hoevelaken, the Netherlands; and Weil am Rhein, Germany. Since acquiring eucatech AG in late 2023, the Group has allocated resources to restore its production capabilities, gradually ramping up output during the Period to supply products for both sales and clinical registries.The Group completed the main structure construction of its largest R&D and production facility in Hangzhou, the PRC, in August 2025, with renovation work expected to begin in the second half of the year. The facility is scheduled to commence operations in 2027, adding an annual production capacity of 2.4 million units.Mr. Chien concluded, “We remain optimistic about the second half of 2025 due to strong momentum in emerging markets, successful proprietary product launches, and strategic partnerships. APAC and EMEA will remain our key growth drivers, with plans to transition selected markets from distributor to direct sales models to enhance revenue and market presence. In Europe, we will establish direct sales teams in Belgium and the Netherlands to expand our footprint. The Japanese market will see renewed momentum through new product launches, while in the PRC market, we will capitalize on policy support to expand product coverage and accelerate commercialization. US shipments are expected to speed up amid easing tariff disputes. Backed by OrbusNeich’s diversified portfolio, strong financial position, and economies of scale, we are well positioned to build a resilient, competitive business that delivers sustainable value to stakeholders.”About OrbusNeich Medical Group Holdings LimitedOrbusNeich is a multinational medical device company specializing in interventional devices for percutaneous coronary intervention (PCI) and percutaneous transluminal angioplasty (PTA) procedures. Headquartered in Hong Kong, China, our Group sells its products in more than 70 countries and regions worldwide. It is also actively expanding into structural heart disease. With an in-house R&D team boasting over 20 years of product development expertise, our Group has developed world-leading proprietary technologies.For more information, please visit the Group’s official website: https://orbusneich.com/. Copyright 2025 ACN Newswire via SeaPRwire.com.

RAS AL KHAIMAH CITY, UAE, Aug 14, 2025 - (ACN Newswire via SeaPRwire.com) - Ras Al Khaimah International Corporate Centre (RAK ICC) has announced significant amendments to its Foundations Regulations 2019, which took effect on 31 July 2025. The changes represent one of the most substantial updates to the regime since its introduction, reinforcing the UAE's position as a competitive jurisdiction for wealth structuring and long-term asset protection.RAK ICC Foundations are widely recognized for their flexibility, confidentiality, and legal robustness, making them a preferred choice for high-net-worth individuals, entrepreneurs, and family offices, both within the UAE and internationally. These structures are commonly used for succession planning, family governance, and consolidating diverse assets under a single legal entity.The 2025 amendments introduce stronger legal safeguards and improved governance measures which include:Firewall Provisions - Stronger protection from foreign judgments conflicting with RAK ICC Regulations.Three-Year Statute of Limitations - Limits challenges to establishment or asset transfers to three years.Cause of Action Provisions - Creditor fraud claims are limited to the specific asset involved and only if rendering the founder insolvent.Duress and Officer Protections - Nullifies actions taken under foreign legal coercion, preserving internal governance autonomy of a foundation.Strengthened Arbitration Framework - Disputes can be resolved privately with court-level powers.Private Trustee Foundation Provisions - Clarifies asset segregation and fiduciary integrity for property held in trust by a foundation.Assets held within RAK ICC Foundation will now benefit from enhanced firewall provisions, ensuring that foreign judgments conflicting with UAE law cannot be enforced against them. A new three-year limitation period has been established for challenging the formation of a foundation or the transfer of assets into it, providing greater certainty for founders and beneficiaries. The reforms also tighten creditor protection rules by requiring proof of insolvency in fraudulent transfer claims, with liability capped at the value of the disputed asset to prevent overreach into unrelated holdings.In addition, the updated regulations address governance integrity and operational resilience. Officers of a foundation who receive foreign orders inconsistent with RAK ICC law are obligated to disregard them, thereby safeguarding the autonomy of the foundation's decision-making. The framework now explicitly confirms that assets held in trust by a foundation are legally distinct and separate from foundation property, ensuring clear asset segregation. Dispute resolution has also been strengthened, with arbitration provisions expanded to grant tribunals court-like powers, enabling disputes to be resolved efficiently, confidentially, and in line with international best practices.These changes are part of RAK ICC's broader strategy to maintain a forward-looking legal and regulatory environment that meets global standards while catering to the specific needs of its client base. They reflect the jurisdiction's commitment to supporting sophisticated wealth planning strategies that balance control, privacy, and long-term security.By enhancing its Foundations regime, RAK ICC is cementing its position in the UAE as a trusted partner for those seeking secure, adaptable, and internationally compliant solutions for wealth preservation and intergenerational planning.About RAK ICCRas Al Khaimah International Corporate Centre (RAK ICC) is a corporate registry based in Ras Al Khaimah, United Arab Emirates. The organisation provides international business companies and foundations, typically used for private and business structuring, asset consolidation, and succession planning. To date, RAK ICC has incorporated thousands of international companies and supports multi-billion dirhams in structured assets. It serves high-net-worth individuals, entrepreneurs, and businesses seeking flexible and secure solutions for long-term business and wealth management.For media enquiries, contact us at:Phone: +971 7 207 7177Email: info@rakicc.comWebsite: https://www.rakicc.com/contact-us/SOURCE: RAK ICC Copyright 2025 ACN Newswire via SeaPRwire.com.

HONG KONG, Aug 12, 2025 - (ACN Newswire via SeaPRwire.com) - MMG Limited (“MMG”, stock code: 1208) has today announced its Interim Results with a net profit after tax of US$566.3 million. This represents more than a 600 per cent increase compared to a net profit after tax of US$79.5 million in the first half of 2024.The strong profit growth was primarily driven by increased copper production across all three copper mines, higher market prices for copper, gold, silver and zinc, as well as reduced unit costs at Las Bambas driven by higher copper production.“Over the first half of the year, our business delivered an outstanding operational and financial performance,” said Ivo Zhao, MMG’s CEO. “This result reflects the strength of our portfolio, the capability of our people, and the disciplined execution of our strategy.”Importantly, MMG’s safety performance improved with a total recordable injury frequency (TRIF) of 1.81 per million hours worked in the first half of 2025, an improvement compared to the full-year 2024 TRIF of 2.06. The significant events with energy exchange frequency (SEEEF) for the first half of 2025 remained consistent with the 2024 figure at 0.78 per million hours worked.Operationally, MMG achieved impressive copper sales and significantly improved production across all three of its copper assets, including a strong performance from Las Bambas and the ramp-up at Khoemacau and Kinsevere. Its Australian operations also maintained solid zinc production, despite navigating challenges including weather impacts, equipment reliability and lower grades due to mining sequence.Highlights include:Record first-half results for both EBITDA and EBIT, with EBITDA at US$1,539.9 million, representing a 98 per cent increase compared to the first half of 2024, and EBIT totalling US$1,058.8 million, an increase of 240 per cent over the same period.Net profit after tax was US$566.3 million, including a profit of US$340.0 million attributable to equity holders of the company.A 130 per cent increase in net cash flow from operations, totalling US$1,185.0 million, compared to the first half of 2024. This performance was mainly driven by increased copper sales and higher commodity prices.Balance sheet improvements, with record lows - since the acquisition of Las Bambas - in both net debt and gearing ratio. The Company’s net debt declined by US$903.3 million since the end of 2024, attributed to robust operational cash flow and the early repayment of US$500 million in Khoemacau Joint Venture Group borrowings. Gearing reduced from 41 per cent to 33 per cent over the first half of 2025.Record high total payable copper sales since 2018, reaching 237,651 tonnes in the first half of 2025.Las Bambas produced 210,637 tonnes of copper in copper concentrate in the first half of 2025, marking a 67 per cent increase compared to the same period in 2024. EBITDA reached a record high of US$1,310.5 million, representing a 122 per cent increase compared to the first half of 2024.“MMG’s balance sheet is in great shape – its strongest in 10 years - with debt reduction driven by higher profits and cash generation,” continued Mr Zhao. “Our ambition to become a top 10 global copper producer is within reach and we are well-positioned to achieve this through operational excellence, disciplined capital allocation, and a continued commitment to responsible mining.”Guidance for the year remains unchanged with total production aiming for a high end of 522,000 tonnes of copper and 240,000 tonnes of zinc. Las Bambas is expected to produce up to 400,000 tonnes of copper this year, assuming stable operating conditions and limited external disruptions. MMG is focussed on delivering its cost targets, with Las Bambas and Rosebery favourably adjusting their C1 cost range to reflect improved by-product credits and strong market conditions.The company is working to complete the recent Nickel Brazil acquisition and is confident in the long-term portfolio and growth contribution. MMG remains committed to supporting community development, strong local economies and employment and supplying the critical minerals the world needs for a sustainable future.Read the 2025 Interim Results announcement, watch a short CEO message and download company photos.About MMG Founded in 2009, MMG’s vision is to create a leading international mining company for a low carbon future. The company is headquartered in Melbourne, Australia and Beijing, China and listed on the Hong Kong Stock Exchange (HKEX1208). MMG’s portfolio supports copper, zinc and cobalt production, with soon to be nickel – products that are critical to achieving global decarbonisation and electrification targets. With operations in Australia, Botswana, the Democratic Republic of Congo and Latin America. More info here. Copyright 2025 ACN Newswire via SeaPRwire.com.

香港, 2025年8月15日 - (亞太商訊 via SeaPRwire.com) - 雲頂新耀今日宣布，旗下創新藥艾曲莫德（VELSIPITY(R)，etrasimod）被納入《2025 ACG 臨床指南：成人潰瘍性結腸炎》（下稱「新版指南」），並獲得強烈推薦用於中重度活動性潰瘍性潰瘍性結腸炎（UC）患者的誘導緩解及維持緩解治療（中等質量證據）。新版指南同時建議，對於已通過鞘氨醇-1-磷酸（S1P）受體調節劑實現誘導緩解的患者，繼續使用艾曲莫德以維持緩解（強烈推薦，中等質量證據）。這一重要進展不僅體現了國際權威醫學指南對艾曲莫德臨床價值的高度認可，也進一步彰顯了其在滿足UC患者未被滿足的治療需求方面的潛力，為全球UC患者提供新的治療選擇。此次新版指南由美國胃腸病學會（American College of Gastroenterology，ACG）制定，基於近五年最新循證醫學證據，系統總結了UC治療及並發症預防的新方法與新進展，為臨床醫生提供規範、科學的管理參考，以更好地應對不同程度的UC患者治療需求。新版指南指出，艾曲莫德作為新一代高選擇性S1P受體調節劑，通過將活化的淋巴細胞滯留於淋巴結中，減少其在腸道中的浸潤，從而降低局部炎症反應，並伴隨外周循環淋巴細胞計數下降。艾曲莫德ELEVATE UC III 期注冊研究（ELEVATE UC 52和ELEVATE UC 12）這兩項隨機、雙盲、安慰劑對照研究均達到了所有主要和關鍵次要終點，分別在第12周和第52周顯著改善臨床緩解率，並實現持久的內鏡下深度黏膜愈合。值得注意的是，研究中100%的臨床緩解均為無激素緩解，安全性良好，與既往研究結果一致。指南也特意強調了與其他現有治療不同的是，艾曲莫德 ELEVATE UC III 期注冊研究中納入了潰瘍性直腸炎，且證實了在此類人群中顯著提升了臨床緩解率（治療12周時，43.2% vs 13.6%, p＜0.001）。此前，艾曲莫德還被納入2024年美國胃腸病學協會（AGA）臨床實踐指南, 推薦作為潰瘍性結腸炎的一線治療。艾曲莫德亞太臨床試驗牽頭研究者、世界胃腸病學會司庫、亞太消化病學會副主席、中華醫學會第十屆消化病學分會副主任委員、中國人民解放軍第四軍醫大學附屬西京醫院吳開春教授表示：「新版指南進一步明確，『實現內鏡黏膜愈合以達成持續無激素緩解和避免住院手術』是中重度潰瘍性結腸炎治療的核心目標，這不僅關系到疾病的長期安全管理，也與改善患者生活質量息息相關。此次指南中，艾曲莫德被強烈推薦用於中重度活動性潰瘍性結腸炎的誘導和維持治療，標志著其臨床價值獲得了國際權威學術機構的高度認可，也為臨床實踐提供了全新的治療選擇。」雲頂新耀首席執行官羅永慶表示：「艾曲莫德此次獲新版指南強烈推薦用於中重度活動性潰瘍性結腸炎的誘導和維持治療，充分體現了其卓越的臨床療效和良好安全性，進一步確立了其作為一線治療新選擇的重要地位。新版指南明確將實現內鏡黏膜愈合作為治療中重度活動性潰瘍性結腸炎的核心目標，印證了黏膜愈合為國內外指南一致認定的重要終點，可顯著降低疾病複發、住院、結直腸切除及結直腸癌風險。值得一提的是，指南特別強調了艾曲莫德在潰瘍性直腸炎患者中同樣可顯著提升臨床緩解率。在亞洲，潰瘍性結腸炎患者人數持續上升，以中國為例，2024年中國的潰瘍性結腸炎患者數量約為80萬人，預計到2030年將達100萬人，現有臨床治療選擇有限，迫切需要兼顧療效、安全性與便利性的創新方案。我們將加速艾曲莫德的商業化進程，助力更多患者長期維持安全有效的疾病緩解，並提升生活質量。」作為雲頂新耀在自身免疫疾病領域布局的核心創新產品，艾曲莫德（維適平(R)）的新藥上市申請已於2024年12月獲中國國家藥品監督管理局正式受理，預計今年年底或明年年初獲批。艾曲莫德已在新加坡、中國澳門和中國香港獲批，其新藥上市許可申請也已在韓國和中國台灣地區獲正式受理。艾曲莫德已被納入粵港澳大灣區內地9市臨床急需進口港澳藥品醫療器械目錄（2024年），在大灣區先行使用，成為雲頂新耀第三款商業化新藥。雲頂新耀已於2025年3月啟動艾曲莫德在嘉善工廠的本地化生產建設項目，支持其在大中華區及其他亞洲市場的供應及商業化落地。 Copyright 2025 亞太商訊 via SeaPRwire.com.

業績亮點：- 收入達83.6百萬美元，同比增長5.9%。- 銷量達919,000件，其中779,000件為自有產品，同比增長8.6%。- 公司擁有人應佔利潤同比上升5.1%至19.8百萬美元。- 核心經營利潤達15.1百萬美元，同比增長11.4%。- 為慶祝集團成立25週年，董事會宣派特別股息每股15港仙。- 財務狀況穩健，截至2025年6月30日，現金及銀行結餘達237.1百萬美元，支持潛在收購及新生產設施建設。- 優質產品獲全球廣泛認可，帶動亞太地區市場收入按年增長14.0%，歐洲、中東及非洲市場增長17.0%，及美國市場增長20.0%。- 於上半年收購一家台灣經銷商，並計劃下半年於比利時及荷蘭設立直銷團隊，進一步加強在亞太地區及歐洲、中東及非洲市場的影響力。- 集團善用全球商業化專長及龐大銷售網絡，與醫療器械同業建立戰略合作，藉此豐富產品組合，並透過交叉銷售創造額外收入。香港, 2025年8月15日 - (亞太商訊 via SeaPRwire.com) - 專營經皮冠狀動脈介入治療（PCI）及經皮腔內血管成形術（PTA）手術介入器械的全球醫療器械製造公司業聚醫療集團控股有限公司（「業聚醫療」或「集團」；股份代號：6929）今天宣佈截至2025年6月30日止六個月(「報告期」)的中期業績。儘管宏觀經濟環境未見明朗，集團的收入及純利仍雙雙錄得增長。美國市場增長強勁，加上亞太地區及歐洲、中東與非洲地區新興市場的持續貢獻，推動集團收入達到83.6百萬美元，較去年同期上升5.9%。核心經營利潤（自本公司擁有人應佔利潤撇除以股份為基礎的薪酬開支、與稅務虧損相關的遞延稅項資產的稅務抵免淨額及融資收入╱成本）為15.1百萬美元，同比增長11.4%。公司擁有人應佔利潤同比上升5.1%至19.8百萬美元。每股基本盈利為2.40美仙（2024年上半年：2.28美仙）。截至2025年6月30日，集團財務狀況保持穩健，現金及銀行結餘達237.1百萬美元。鑑於集團的財務狀況穩健，以及為慶祝成立25週年，董事會議決宣派特別現金股息每股普通股15港仙，彰顯集團致力為股東創造價值。連同截至2024年12月31日止年度之末期股息每股10港仙（已於2025年6月16日派付），股東於2025年合共獲派股息每股25港仙。業聚醫療董事長、執行董事兼首席執行官錢永勛先生表示：「過去25年，我們持續投資於創新及全球商業化能力，除了為業聚醫療建立了聲譽，也助我們在不同的經濟週期中破浪前行。儘管2025年上半年面臨宏觀經濟及地緣政治的雙重挑戰，我們的全球佈局仍展現韌性。美國市場增長印證了市場對我們的優質產品需求殷切，而我們亦透過龐大的銷售網絡，成功把握了亞太地區及歐洲、非洲及中東地區的增長機遇。我們將繼續透過直銷市場覆蓋、卓越的銷售支援、對創新的投入，以及全面的PCI和PTA產品組合提升品牌價值，從而強化競爭優勢，為醫生及患者提供更安全有效治療方案的同時，也為股東創造長遠回報。」全球銷售網絡及合作夥伴關係推動收入增長業聚醫療已建立覆蓋逾70個國家及地區的銷售網絡，在13個地區設立直銷團隊並建立全球經銷商網絡，成為把握各地機遇、回應當地需求的重要一環。期內，受惠於印尼市場增長，以及Scoreflex TRIO 在新加坡及馬來西亞獲更廣泛採用，亞太地區收入同比上升14.0%至27.3百萬美元。歐洲、中東及非洲市場方面，德國、法國及西班牙等直銷市場及包括英國、斯洛伐克及捷克共和國在內的分銷市場的自有球囊類產品銷售表現強勁，帶動該區收入上升17.0%至22.4百萬美元。儘管受關稅因素影響，美國市場收入仍同比上升20.0%至8.0百萬美元，主要受冠脈的普通及刻痕球囊，包括高價產品Scoreflex NC球囊，以及外周球囊銷量顯著上升所推動。而日本及中國境內市場的收入分別為16.1百萬美元及9.7百萬美元。憑藉其廣受認可的全球商業化能力，集團與立志走向國際巿場的同業合作，藉此豐富產品組合並開拓額外收入來源。繼去年與深圳開立生物醫療科技股份有限公司成功展開合作，在香港及澳門分銷血管內超聲產品後，集團與該夥伴再度簽訂獨家分銷協議，在新加坡及馬來西亞分銷相關產品。至目前為止，合作範圍已進一步擴展至集團旗下位於歐洲的4個直銷市場，包括法國、德國、西班牙及瑞士，及其他6個分銷市場。性能主導的多元化創新產品組合，提升市場差異化水平截至2025年6月30日，業聚醫療在全球主要司法管轄區擁有逾250項授權專利及已公佈專利申請，及逾55款獲批產品。期內，集團產品註冊及臨床試驗繼續取得進展，包括：- Sapphire 3的美國臨床試驗進展順利，預期於2025年第四季度完成病人入組，以支持該產品的FDA納入CTO適應症，從而與市場上其他傳統半順應性球囊形成差異化；- JADE PLUS及Teleport Glide獲得CE標誌、Teleport Glide及Scoreflex QUAD獲得PMDA批准、COREPASS模組化微導管獲得FDA批准、導引導管獲得國家藥監局批准；- 就Scoreflex TRIO、Sapphire ULTRA、Sapphire NC ULTRA、Sapphire NC 24、JADE PLUS、Teleport XT及Teleport Glide向國家藥監局提交註冊申請，並就Vascuaid抽吸導管及大管腔延長導管向PMDA提交註冊申請。集團擁有龐大的產品管線。在冠狀動脈領域，Sapphire PTX紫杉醇藥物塗層球囊大約於2025年底在日本展開臨床研究；外周方面，JADE Score球囊則預期於2026年向PMDA提交註冊申請。合資企業業聚培福在中國境內展開的TricValve臨床試驗亦取得重大進展，參與醫院數量上升，加快了病人入組進度。此外，業聚培福亦正透過「港澳註冊藥品及醫療器械進入大灣區計劃」，積極推動大灣區各大醫院採用TricValve。TricValve於2025年7月完成首次在中國境內進行的商業化植入手術，達到重要的里程碑。多區域生產基地緩解地緣政治風險截至2025年6月30日，業聚醫療於中國深圳、荷蘭荷佛拉肯，以及德國萊茵河畔魏爾設有生產基地，總年產能約為210萬件球囊及支架。自2023年底收購eucatech AG以來，集團已投入資源恢復其生產能力，期內產量逐步提升，以供應銷售及臨床註冊所需產品。2025年8月，集團完成位於中國杭州、旗下最大研發及生產基地的主體結構建設，裝修工程預期於下半年展開。該基地計劃於2027年投產，屆時將新增年產能240萬件。錢先生總結說：「有見於新興市場的強勁勢頭、自研產品陸續成功推出巿場，以及已建立的戰略合作，我們對2025年下半年前景保持樂觀。除了亞太地區及歐洲、中東及非洲將繼續擔當主要的增長引擎，我們亦計劃將部分市場由分銷模式轉為直銷模式，以強化當地營收能力及市場滲透。歐洲市場將透過於比利時及荷蘭設立直銷團隊加強市場影響力；日本市場則藉新產品上市重拾增長動力；而在中國境內市場，我們則把握政策支持，擴大產品覆蓋並加速商業化進程。隨著關稅爭端緩和，美國市場的產品交付亦有望加快。憑藉業聚醫療多元化的產品組合、穩健的財務狀況及規模經濟效益，我們具備優勢構建具韌性及競爭力的業務體系，為持份者創造可持續的價值。」關於業聚醫療集團控股有限公司業聚醫療是一家全球醫療器械製造公司，專門生產用於經皮冠狀動脈介入治療（PCI）及經皮腔內血管成形術（PTA）的介入器械。本集團總部位於中國香港，產品銷往全球超過70個國家和地區。集團亦積極將業務擴展至結構性心臟病領域。憑借擁有逾20年產品開發經驗的內部研發團隊，本集團已開發出世界領先的專有技術。如需瞭解更多詳情，請訪問集團官網：https://orbusneich.com/ Copyright 2025 亞太商訊 via SeaPRwire.com.

香港, 2025年8月15日 - (亞太商訊 via SeaPRwire.com) - 近日，中國電子信息行業聯合會公佈最新一批獲頒數據管理能力成熟度（簡稱「DCMM」）等級証書企業名單，廣發証券獲評最高等級五級（優化級）認証，成為行業首家獲評最高等級的証券公司，標誌著公司在數據管理和應用方面達到國內領先水平，為行業數據管理能力建設樹立標杆。《數據管理能力成熟度評估模型》（GB/T 36073-2018）是中國數據管理領域正式發佈的首個國家標準。該認証從數據戰略、數據治理、數據架構、數據應用等多個維度，全面評估企業的數據管理能力。其中，五級（優化級）作為最高等級，標誌著企業的數據管理已形成行業最佳實踐，具備強大的示範引領作用。一直以來，廣發証券高度重視數據管理能力的建設與提升，將數據視為企業核心資產。公司構建了「戰略引領、全員參與、跨部門協同、全生命週期管理」的數據管理體系。通過制定清晰的數據戰略規劃，完善數據治理組織架構與制度流程，強化數據安全與合規管理，持續提升數據質量與應用效能，公司實現了數據管理從「規範」到「優化」的跨越式發展，為業務創新、客戶服務升級及風險管理提供了強有力的數據支撐。廣發証券副總經理、首席信息官辛治運表示：「公司將以此次獲得DCMM五級認証為新的起點，持續深化數據管理能力建設，進一步完善數據治理長效機制，推動數據技術與業務場景的深度融合，並以此為契機，不斷提升服務實體經濟的質效，為証券行業的數據管理創新與發展貢獻更多力量。」 Copyright 2025 亞太商訊 via SeaPRwire.com.