Month: 2024-08

香港, 2024年8月30日 - (亞太商訊 via SeaPRwire.com) — 2024年8月28日，復星國際（HKEX: 0656）公佈2024年中期業績。報告期內，總收入保持增長，達人民幣978.4億元；產業運營利潤保持增長，達人民幣34.7億元，歸母淨利潤為人民幣7.2億元。復星國際董事長郭廣昌在29日上午的業績發佈會上表示，「上半年，儘管宏觀環境充滿挑戰，我們堅定執行聚焦主業戰略，圍繞形成優勢的產業賽道，打造行業數一數二的好公司、好產品，總體來看卓有成效。我們將持續聚焦創新、聚焦全球化，同時注重輕資產運營，以具備競爭優勢的核心能力驅動長遠發展。」今年以來，國內經濟恢復不穩固，國際市場持續波動，讓包括復星在內的中國企業面臨諸多挑戰。復星持續推進戰略聚焦，以核心能力驅動企業發展，實現核心產業提質增效，資產底盤保持穩健。分析人士認為，從復星中期業績報告釋放的信息來看，復星聚焦家庭消費核心產業，先人一步推進創新和全球化，這一戰略持續為復星夯實業務底盤，帶來可預期的穩定贏利；同時，這兩年復星積極推進輕資產運營，優化資產組合，持續降低桿杆，現金儲備充裕，財務安全墊日漸厚實，有望推動市場對復星的價值進行重估。全球化和創新「先人一步」，打造「數一數二」的企業和產品 今年上半年，復星四大核心子公司——復星醫藥、豫園股份、復星葡萄牙保險、復星旅文，總收入達人民幣721.7億元，佔集團總收入的比重達到74%。復星聚焦主業的效果進一步顯現，其在醫藥、旅遊、消費、保險等核心產業賽道的優勢持續提升。在上述核心賽道，通過多年努力，復星已打造出多個在行業排名前列的「數一數二」的企業和產品。例如，復星醫藥位列中國醫藥工業百強第二名，今年上半年也連續第三年入選全球藥企管線規模前二十強；復宏漢霖是首個在港股贏利的中國創新生物製藥公司，旗下多款自主開發的單抗生物類似藥，引領中國生物醫藥行業快速發展，首款重磅產品漢利康是首個獲批上市的國產生物類似藥；復星葡萄牙保險在葡萄牙保險市場市佔率保持第一，在全球葡語區保險市場居前列；智造板塊的翌耀科技是全球領先的自動化和數字化企業。此外在快樂業務板塊，復星旅文旗下Club Med是精緻「一價全包」度假的全球領導者；三亞亞特蘭蒂斯是國內領先的高端綜合度假旅遊目的地，推動海南旅遊進入3.0時代；豫園旗下老廟黃金，是中華老字號，更是享譽全國的珠寶品牌。這些在各自行業「數一數二」的企業和產品，幫助復星持續鞏固在相關產業的領導地位。對復星而言，穩健贏利的增長來自兩個方面，一是創新，一是全球化。在當前國內經濟「內捲」的大環境下，「出海」成為企業界的「必答題」。但復星早在2007年便啟動全球化征程，在海外摸爬滾打17年，今天已成為植根中國的標杆性的全球化企業之一、在全球超過35個國家和地區擁有深度產業佈局。17年出海征程裡，復星捕獲了很多成功的項目，也遇過很多挑戰，最重要的意義在於鍛造了國內企業稀缺的全球化能力，並在全球打通不同市場、不同業態和資源，實現了全球佈局、全球運營和全球發展，全球化深度運營能力持續提升。有一組數據非常能闡釋情況，2024年上半年，集團海外收入達人民幣458.7億元，同比增長4%，佔總收入的比重上升至47%，近半收入來自海外，這在中國企業中並不多見。更重要的是，復星在全球化過程中積極推進旗下企業生態賦能與協同，旗下海內外成員企業在全球化研發、業務拓展、運營及投融資等方面取得多項進展。上半年，復星旗下企業的生物藥出海再獲突破。復星旗下的復宏漢霖，自主開發的漢曲優獲得美國食品藥品監督管理局批准上市，成為在中國、歐盟、美國獲批的「中國籍」單抗生物類似藥；中國首個生物類似藥漢利康獲得秘魯藥監局批准上市，成為繼漢曲優和漢斯狀後，復宏漢霖第三款海外獲批上市的自研藥品。再如復星旅文Club Med地中海俱樂部在全球運營67家度假村，2024年上半年營業額再創新高，達人民幣88.9億元，同比增長10.3%。其中，歐非中東及美洲區持續增長，亞太區復蘇顯著。2024年5月，Club Med 在阿曼簽約中東首個度假村。復星葡萄牙保險，從葡萄牙出發積極拓展海外市場，今年上半年取得葡萄牙境內和國際業務雙增長，海外業績佔比進一步提升，國際業務錄得總保費歐元8.85億元，佔比超過30%；國際業務淨利潤約歐元0.51億元，佔比超過40%。復星旗下全球領先的自動化和數字化企業翌耀科技，也在靜悄悄推進海外拓展，2024年上半年海外新增訂單達到人民幣39.9億元，其中美國市場訂單大幅增加，新增訂單達到人民幣7.5億元，同比增長超過一倍。創新同樣是復星長期積累並始終堅持的核心能力。報告期內，復星持續深化科技與創新能力，創新投入達人民幣35億元；全球視野下的整合式創新模式更加成熟，一批突破性成果正持續為復星帶來穩健贏利，成為復星的增長動力。從創新藥研發方面來看，復星醫藥共有4個產品共9項適應症獲批上市，4個產品共9項適應症進入上市前審批/關鍵臨床階段，9項產品（按適應症計算）獲批開展臨床試驗。復宏漢霖自主研發並生產的創新生物藥不斷取得突破性進展，全球首個一線治療小細胞肺癌的抗PD-1單抗漢斯狀已獲批4項適應症，累計惠及患者超7.5萬，對外授權覆蓋美國、歐洲、東南亞、中東和北非等70多個國家和地區。此外，新一代口服血小板生成素受體激動劑（TPO-RA）蘇可欣新適應症也獲得國家藥監局批准。尖端醫療器械及創新療法的佈局也取得新進展。2024年6月，直觀復星總部產業基地在上海啟用，是直觀醫療在亞太地區最大的研發、生產和培訓一體化基地，達芬奇手術機器人國產化顯著提速。直觀復星Ion支氣管導航操作控制系統也於2024年3月通過國家藥監局批准，並於7月上市。 「輕資產運營」打法成型，價值重估可期得益於業務面的堅實支撐，復星財務面也持續改善。報告期內，復星持續優化資產組合，降低桿杆，財務狀況保持穩健。截至報告期末，集團調整後總債務佔總資本比率為50.2%，維持了2020年以來的下降趨勢；調整後NAV為每股港幣17.4元，顯示當前復星國際股價被嚴重低估。復星也在積極夯實財務安全墊，保持充裕的現金儲備。這次報告期內，復星國際現金、銀行結餘及定期存款達到人民幣1095.5億元，較2023年底增加人民幣約171億元。上市17年來，累計分紅港幣256億元，分紅率逐漸提升，近五年分紅率在20%及以上。就在 2024年6月，國際評級機構標普也充分肯定復星財務戰略成效，確認評級展望為「穩定」。在通過持續的創新和全球化實現穩定贏利的同時，復星面對新的市場環境，也繼續推進「瘦身健體」，陸續退出一些非核心產業，同時積極推進「輕資產運營」，打法也逐漸成型。2024年5月，復星出售德國私人銀行HAL 99.74%股份，引起市場關注，交易完成後，復星將不再持有HAL股份，但全額保留HAFS基金服務業務，以輕資產運營模式，管理約千億歐元資產。在文旅賽道，復星的輕資產運營模式成效顯著，Club Med、三亞亞特蘭蒂斯、太倉阿爾卑斯等IP成為國內旅遊行業標杆。報告期內，Club Med採用租賃及管理模式的度假村佔比為85%，自持度假村佔比降至15%。2024年4月，復星旅文在麗江地中海國際度假區打造的全新IP——阿美澤雪山營地對外開放後，迅速火爆「出圈」，帶動度假區內Club Med麗江度假村與麗江地中海棠岸度假酒店入住率顯著提升。2024年6月，復星旅文還攜手太倉市政府共同打造一站式冰雪主題旅遊度假目的地太倉阿爾卑斯國際度假區二期。該項目總投資超人民幣50億元，由太倉市政府平台出資打造，由復星旅文運營管理。此前復星旅文對阿爾卑斯雪世界的成功運營，為二期項目提供了信心和動力，該項目有望打造多項「世界雪場之最」。與此同時，復星攜手合作夥伴打造了一批產業基金，深度佈局優勢產業。2024年3月，復星醫藥依託在生物醫藥領域的領先優勢，聯手深圳市引導基金等其他七方投資人，共同出資設立人民幣50億元生物醫藥產業基金，募集資金全部投資於生物醫藥、細胞和基因等領域。復星醫藥旗下復健資本通過深圳市公開遴選中標，獨家管理該基金。4月，深圳市政府與復星簽署戰略合作框架協議，雙方集聚優質創新資源，進一步加強在生物醫藥、文體旅遊、時尚消費等領域的合作。也是在2024年4月，復星創富聯合武創投、武漢基金，設立人民幣30億元產業基金，首期規模人民幣11億元。這是湖北省設立人民幣200億元政府引導基金以來，第一隻出資的市場化基金，主要聚焦新一代信息技術、雙碳、智能製造、大消費四大賽道。面對當前的市場環境，可以預計，未來復星仍將積極推進輕資產運營，持續擴大「朋友圈」，加強與各方深度合作，通過優勢互補，實現共贏。多位市場分析人士認為，復星通過創新和全球化的核心戰略，推動業務實現持續穩定盈利，通過退出非核心產業、輕資產運營，持續降債等措施，保持財務面的穩健，有望推動市場對復星的價值重估。郭廣昌認為，未來投資者會更加看重核心產業增長和現金流的穩健，「一次性的資產出售都是短期的，核心業務的成長，才是企業穩健贏利的核心因素」，復星希望打造一個聚焦核心產業的家庭消費產業集團，產業的發展和贏利更可預期。無論是集團層面還是每一塊業務，都要給客戶、投資人提供風險可控、能穩健成長的企業價值。 Copyright 2024 亞太商訊 via SeaPRwire.com.

香港, 2024年8月30日 - (亞太商訊 via SeaPRwire.com) — 2024年，資産荒已成共識，投資者夢寐以求尋找不怕火煉的“真金”。受此影響，具有業績高確定性和高股息的資産價值凸顯。銀河證券策略首席分析師楊超指出，當前，投資者對于現金回報的重視程度日益提升，促使上市公司更積極地采取措施，主動提升分紅頻次與分紅力度。Choice數據顯示，截至8月29日，已有超百家港股上市公司披露中期分紅計劃，包括中國移動（0941.HK）、中國聯通（0762.HK）、九龍倉置業（1997.HK）、中教控股（0839.HK）、李寧（2331.HK）、朝雲集團（6601.HK）等各領域頭部公司。不過，持續高額分紅幷非易事。當前有中期分紅計劃的公司中，“中字頭”港股公司的實力不言而喻，而其他公布派息計劃公司也有一個共同特點，就是構建了有强大核心競爭力的行業優勢。比如九龍倉置業兩個重要商場保持穩定，業績就能穿越地産周期；比如李寧在跑步、籃球和健身三大核心專業品類上保持了科技創新；朝雲集團則以技術創新功效性産品，以履帶式爆品矩陣保持高質量可持續穩利潤發展。由此可見，能長期保持高比例派息的公司，全因其具備同業不可複製的優勢，下面就以朝雲集團為例詳作分析。一、爆品矩陣做“壓艙石”上市公司能够實施持續的高額派息，同行業內保持强競爭力，擁有良好財務狀况和盈利能力的體現。朝雲集團已連續3個半年度業績期營收純利均有雙位數的增長。8月26日發布的財報顯示，2024年H1，公司營收12.49億元（人民幣，下同），同比增長10.3%；純利1.76億元，同比增長29.6%；公司資金儲備充裕，現金、現金等價物及各項銀行存款總額為人民幣26.65億元，中期保持40%的高額派息。“履帶式爆品矩陣”是朝雲集團業績增長的核心驅動力，內在邏輯是公司産品創新能力持續增强。朝雲集團持續進行産品開發和升級，打造了多款强功效性、成分健康、體驗感好、顔值高的大單品，實現産品結構優化幷提升高利潤率産品占比。根據NielsenIQ零售市場數據，朝雲集團的殺蟲驅蚊産品連續十年（2015年－2024年）在中國同類産品中的綜合市場份額排名第一。在新爆品和高複購驅動下，今年上半年，家居護理産品類別收入11.64億元，同比增長11.5%。可以預見，隨著健康與品質生活理念的普及，高品質産品將持續推動朝雲集團業績高質量可持續穩利潤增長。與此同時，公司還憑藉前瞻性市場布局和資源整合能力，從家居護理和個人護理領域向高潜力的寵物護理領域擴張，用强者恒强的邏輯書寫新的篇章。二、“它經濟”的新增長極成了以家清品類作為基本盤且保持穩利潤、可持續發展的朝雲集團，在寵物賽道的布局上也被市場視爲未來增長的重要勢能。而從這份中報看，公司逐漸將這股勢能成功轉化為動能。朝雲集團通過打造人寵互動休閑娛樂的治愈系消費新場所，主打購物中心及生活社區消費業態。公司旗下擁有爪爪喵星球及米樂乖乖寵物生活館兩大實體寵物店品牌，自去年3月開始，展開火速開店模式，截至今年6月30日，已在全國6大城市開設46家門店，遍布深圳、上海、成都、杭州、蘇州、重慶等地。同時，為更符合當下年輕消費群體的審美需求，在集團品牌團隊的支持下，成功完成了寵物門店改造，品牌形象更加突出，更易于被消費者接受，提升了年輕消費群體的覆蓋率。據瞭解，改造後門店收入同比增長233%。中金公司發布研報指出，朝雲集團寵物賽道雙位數擴容可期。公司拓展寵物實體服務業態，成功建立寵物業務護城河。寵物業務與家居清潔、個人護理兩大業務板塊交相輝映，打造了朝雲集團高質量穩增長的多引擎。三、發展潜力兌現，多品牌多品類布局成就全渠道高增長受益于核心業務板塊的成長，朝雲集團實現了新電商渠道高質量穩利潤發展和綫下渠道提質擴容的幷行。今年上半年，綫下實現營收8.43億元，同比增長6.5%；綫上實現營業收入4.06億元，同比增長18.9%。這也說明朝雲集團全渠道發展戰略正在兌現潜力。尤為值得關注的是，公司新電商渠道增勢亮眼。以抖音為例，朝雲集團打造了 “超威驅蚊小綠瓶”等億元單品，長期占據平臺品類各榜單首位，新電商增幅達到300%。未來，以多品牌多品類全渠道的長期增長為方向，朝雲集團有望成為消費品板塊獨特的Alpha。四、業績增速與派息“雙高”，港股投資者的“夢中情司”？綜合上述分析，在消費品板塊衆多公司中，朝雲集團構築起好技術、好産品、好渠道的業務壁壘，形成了同行難以複製的競爭優勢。這一優勢保證了朝雲集團能同時實現高增長、穩利潤和持續高額派息。因此，公司契合了成長投資和價值投資兩種市場風格的特點，完美符合巴菲特曾提出的“成長和價值本是同根生”。我們預計，朝雲集團投資者有望獲得較强的收益確定性。一方面，港股高股息資産長期效益顯著，根據《證券市場周刊》統計，配置港股高股息資産隨著時間的拉長獲得投資回報的概率呈現規律性和顯著性；另一方面，港股市場深度調整後，估值水平已處于歷史相對低位，朝雲集團亦形成“估值窪地”，資産性價比愈發凸顯。可以預見，隨著業績高增長與高派息策略延續，像朝雲集團這樣持續高派息的公司將繼續領跑行業。 Copyright 2024 亞太商訊 via SeaPRwire.com.

- 全球首創新藥雙功能葡萄糖激酶激活劑（GKA）多格列艾汀（商品名：華堂寧®）于2023年底成功納入《國家基本醫療保險、工傷保險和生育保險藥品目錄》（“國家醫保藥品目錄”）。華領醫藥與商業化合作夥伴拜耳以及80家一級經銷商共同推動多格列艾汀的商業化，開始進入中國31個省級醫藥市場。- 2024年1月1日新版“國家醫保藥品目錄”正式執行，2024年上半年，多格列艾汀的銷售量顯著增加。截至2024年6月30日，共銷售84.6萬盒，實現銷售收入人民幣1.027億元，相比2023年6月30日，同比增長46%。- 得益于政府支持創新藥品的市場准入政策，多格列艾汀加速進入上海、北京和天津等地醫院。截至2024年6月30日，已有2100多家醫院和2900多家藥店開始了多格列艾汀的處方銷售。多格列艾汀在醫院、藥店和網絡藥店銷售的比例分別為72%、20%和8%。- 2024年上半年，公司毛利約為4780萬元，毛利率為46.5%。截至2024年6月30日，公司銀行結餘及現金約13.388億元，相比2023年6月30日，同比增長51.9%。- 多格列艾汀的生産能力繼續擴大，預計2024年産能將達到300萬盒以上，公司已經與合作夥伴建立了更大産能的新工藝，正在接受生産許可部門的監管審查。- 上市後臨床研究加速進行，其中HMM0601研究已入組1368例患者，該研究旨在通過收集2000例2型糖尿病患者1年的臨床安全性數據來評估多格列艾汀的長期安全性。HMM0701研究已入組102例患者，該研究是一項前瞻性真實世界研究，旨在探索多格列艾汀在改善血糖穩態、認知功能和糖尿病緩解方面的臨床獲益。自2022年10月上市銷售以來，過去20個月約有10萬名患者使用多格列艾汀，藥物安全性良好。- 公司與中國香港臨床研究人員合作開展了兩項孟德爾隨機化研究，結果顯示，激活葡萄糖激酶（GK）在降低心血管疾病風險和血脂异常風險方面具有長期獲益性，研究結果已經發表在《心血管糖尿病學》雜志上。公司將携手商業化合作夥伴進一步探索多格列艾汀更加廣泛的臨床適應症。香港, 2024年8月30日 - (亞太商訊 via SeaPRwire.com) — 華領醫藥（“公司”，香港聯交所股份代號：2552）宣布公司及其附屬公司截至2024年6月30日止，6個月（“報告期”）未經審核的綜合業績，以及公司上半年業務進展和未來業務展望。華領醫藥創始人、首席執行官陳力博士表示：“2024年上半年是華領醫藥商業化進程的又一個里程碑。多格列艾汀成功納入國家醫保藥品目錄，大大提升了患者用藥的可及性和可負擔性。在國家和各級政府全鏈條支持生物醫藥産業發展的背景下，在公司與商業化夥伴和生産夥伴的共同努力下，多格列艾汀正迅速提升産能，加速進入全國各地的醫院和藥房，以惠及更多患者。隨著用藥人數的持續增長，多格列艾汀的安全性得到了良好的驗證，其經濟效益和社會效益也大幅提升，為公司未來發展注入了信心。通過銷售擴張和優化運營，我們希望能够在2025年實現公司盈利。目前，華領醫藥還正在全球範圍內開展多格列艾汀的基礎研究和臨床研究，希望不斷拓展多格列艾汀的適應症和適用人群，探索更加廣泛的疾病應用領域，造福不同的患者人群。”臨床研究和公司運營進展摘要- 進入國家醫保藥品目錄後，多格列艾汀速進入醫院和藥店，尤其在上海、北京、天津等城市，政府推出了支持創新藥進入市場的政策。截至2024年上半年，多格列艾汀已經進入全國2100多家醫院。- 上半年，多格列艾汀實現銷售收入人民幣1.027億元，預計在2024年下半年將繼續增長。基于進入醫保建立的新基礎，公司正不斷與合作夥伴密切協作，優化多格列艾汀的生産流程，提高生産效率，從而擴大産能幷降低生産成本。- 公司繼續在約80家醫院開展上市後真實世界研究，增進瞭解多格列艾汀對于2型糖尿病及其幷發症（如記憶力减退、糖尿病腎病）患者的獲益。除此之外，通過與中國香港的臨床研究夥伴的合作，我們使用孟德爾隨機化(MR)研究發現激活GK可以降低心血管疾病和血脂异常風險，有助于公司通過多格列艾汀進一步瞭解GK激活的更多獲益，幷探索多格列艾汀新的適應症。孟德爾隨機化是一種統計方法，利用遺傳變异體來研究暴露（如治療）對結果（如疾病）的因果效應。MR的獨特優勢在于它比傳統的觀察性研究更不容易受到混雜因素和時間相關偏倚的影響，因此在循證醫學中，當隨機對照試驗不可實施時，MR被視為最高循證醫學證據。- 公司正在積極推進針對2型糖尿病患者的上市後真實世界研究，包括在中國內地的HMM0601研究和HMM0701研究，以及在中國香港的HMM0123研究。在這些研究中，公司正不斷積累多格列艾汀單獨用藥，以及多格列艾汀與二甲雙胍、DPP-4抑制劑、SGLT-2抑制劑、GLP-1RA和胰島素等聯合用藥的臨床數據，以優化血糖穩態治療的臨床證據，幷且為多格列艾汀拓展在糖尿病預防和緩解等方面的適應症提供新的證據。- 公司正在持續豐富藥物開發管綫，尤其是固定複方製劑的開發。多格列艾汀-二甲雙胍固定複方劑量已經進入生産工藝驗證階段，公司預計將于2028年推出2型糖尿病治療的新藥。未來，公司將開發更多的多格列艾汀固定複方製劑新藥用于糖尿病及其幷發症，如肥胖、糖尿病腎病等的個性化治療。- 為了進一步發揮多格列艾汀在修復伴有肥胖的糖尿病患者的GLP-1分泌方面的獨特優勢，公司在美國啓動了第二代GKA的1期臨床研究。目前，試驗進展順利，在3組2型糖尿病患者中完成了劑量遞增。公司預計在2024年第四季度發布頂綫數據，以支持未來的藥物開發。- 在2024年美國糖尿病協會（ADA）科學年會上，公司報告了多項基礎研究和臨床研究進展。一項研究顯示，多格列艾汀聯合SGLT-2抑制劑可以改善血糖控制，聯用效果優于兩者單獨用藥，幷且提示多格列艾汀有望在新的適應症中發揮作用，用于與SGLT-2抑制劑恩格列淨等慢性腎病治療藥物聯合用藥，治療中晚期糖尿病腎病患者。- 公司正在使用孟德爾隨機化研究的框架探索多格列艾汀更多的藥物使用機會，如腎病、神經病變相關疾病、眼部相關疾病、認知障礙和癌症等。公司將進一步利用動物研究驗證更多可能的機遇。- 公司將持續優化蛋白變構調節技術，幷積極擴展應用領域，推進負向變構調節劑在GK和GPCR蛋白上的應用。目前葡萄糖激負向變構調節劑已經進入臨床前藥物候選階段，作為先天性高胰島素血症和潜在的血脂异常症的臨床候選藥物。公司將繼續推進mGLUR5 NAM項目在帕金森病（PDLID）、脆性X染色體綜合征(FXS)和藥物成癮中的臨床潜力。財務摘要截至2024年6月30日止，- 公司銀行結餘及現金約13.388億元- 銷售收入約為人民幣1.027億元，共銷售84.6萬盒華堂寧®- 其他收入約為5510萬元，其中拜耳里程碑收益攤銷約4780萬元- 開支總額約2.459億元，其中研發開支約1.198億元前瞻性聲明本文包含有關華領醫藥以及産品未來預期、計劃和前景的陳述。該等前瞻性陳述僅與本文作出該陳述當日的事件或資料有關，可能因未來發展而出現變動。除法律規定外，于作出前瞻性陳述當日之後，無論是否出現新資料、未來事件或其他情况，我們幷無責任更新或公開修改任何前瞻性陳述及預料之外的事件。請仔細閱讀本文幷理解，由于各種風險、不確定性或其他法定要求我們的實際未來業績或表現可能與預期有重大差异。關于華領華領醫藥是一家總部位于中國上海的創新藥物研發和商業化公司，在美國、中國香港設立了公司。華領醫藥專注于未被滿足的醫療需求，為全球患者開發全新療法。華領醫藥彙聚全球醫藥行業高素質人才，融合全球創新技術，依托全球優勢資源，研究開發突破性的技術和産品，引領全球糖尿病醫療創新。公司核心産品華堂寧®（多格列艾汀片）以葡萄糖傳感器葡萄糖激酶為靶點，提升2型糖尿病患者的葡萄糖敏感性，改善患者血糖穩態失調。2022年9月30日，華堂寧®已獲得中國國家藥品監督管理局（NMPA）的上市批准，用于單獨用藥或者與二甲雙胍聯合用藥，治療成人2型糖尿病。對于腎功能不全患者，無需調整劑量，是一款可用于不同程度的腎功能損傷（包括未進行透析的終末期腎損）的2型糖尿病患者的口服降糖藥物。華領醫藥將與領軍企業拜耳共同推動華堂寧®在中國的商業化推廣，以造福糖尿病患者及其家庭。詳情垂詢華領醫藥網址：www.huamedicine.com投資者電郵：ir@huamedicine.com媒體電郵：pr@huamedicine.com新聞免責聲明本材料，如爲上下文論述的準確性和完整性，提及在中國上市的産品相關信息的，特別是標識或要求，應遵循中國監管機構批准的相關文件。另外，相關信息不應被解讀爲對任何藥物或者診療方案的推薦或者宣傳，亦不應替代任何醫療衛生專業人士的醫療建議，涉及醫療的相關事宜務必諮詢醫療衛生專業人士。 Copyright 2024 亞太商訊 via SeaPRwire.com.

- Dorzagliatin (trade name: HuaTangNing, world's first dual-acting glucokinase activator (GKA), successfully entered China’s National Reimbursement Drug List for Basic Medical Insurance, Work-related Injury Insurance and Maternity Insurance (the “NRDL”) at the end of 2023. Hua Medicine worked with sales promotion partner Bayer Healthcare Company Limited (“Bayer”) and 80 Tier 1 distributors to begin the pharmaceutical market entry in 31 municipalities and provinces in China.- The new NRDL became effective on January 1, 2024. In the first half of 2024, the sales volume of dorzagliatin increased significantly. As of June 30, 2024, sales of HuaTangNing reached 846,000 packs with a sales revenue of RMB102.7 million. The sales revenue increased by 46%, compared with the six months ended June 30, 2023.- Dorzagliatin experienced a fast entry into hospitals, especially in Shanghai, Beijing, Tianjin where the government policies support market entry for novel new drugs. By the end of June 30, 2024, dorzagliatin was prescribed in over 2,100 hospitals and over 2,900 pharmacies. Dorzagliatin was sold principally through hospitals (approximately 72% of total sales), with the remainder of sales through pharmacies (20%) and internet drug stores (8%).- Gross profit in the first half of 2024 is RMB47.8 million, representing a gross profit margin of 46.5%. Bank balances and cash position increased by 51.9% to approximately RMB1,338.8 million for the six months ended June 30, 2024, compared with the six months ended June 30, 2023.- Dorzagliatin manufacturing capacity continues to expand, with the expectation to reach 3 million packs in 2024. New processes for larger capacity have been established with our partners and are under regulatory review for production permit.- Post marketing clinical studies proceeded at an accelerated rate, in which HMM0601 enrolled 1,368 patients and HMM0701 enrolled 102 patients. HMM0601 is designed to evaluate the long-term safety of dorzagliatin by collecting 1-year clinical safety data in 2,000 T2D patients and HMM0701 is a prospective real-world study to explore dorzagliatin’s clinical beneficial effects on the improvement of glucose homeostasis, cognitive function and diabetes remission. A good drug safety profile for dorzagliatin has been observed since its commercial launch in October 2022 – a time span of over 20 months and approximately 100,000 patient exposure.- Two Mendelian randomization studies conducted by our collaborating Hong Kong-based clinical investigators, and published in Cardiovascular Diabetology showed that glucokinase activation can lead to long term benefits in reduction of risks in cardiovascular diseases and dyslipidaemia. New clinical indications shall be further explored with our commercialization partner.HONG KONG, Aug 30, 2024 - (ACN Newswire via SeaPRwire.com) - Hua Medicine (the "Company", HKEx: 2552) today announces the unaudited consolidated results of the Company and its subsidiaries for the six months ended June 30, 2024 (the "Reporting Period"), and the Company’s business progress for the first half of the year and business outlook.Dr. Li Chen, the founder and CEO of Hua Medicine, said, “The first half of 2024 marks a milestone for the commercialization efforts of Hua Medicine. Dorzagliatin's successful inclusion in China’s National Reimbursement Drug List has significantly improved patient accessibility and affordability. Against the backdrop of comprehensive support from the national and local governments for the development of the biopharmaceutical industry, and with the joint efforts of the Company, commercial partners, and production partners, the production capacity of dorzagliatin is rapidly increasing, accelerating its entry into hospitals and pharmacies nationwide to benefit more patients. With the continued growth in the number of users, the safety of dorzagliatin has been well validated, and its economic and social benefits have also greatly increased, instilling confidence in the Company's future development. Through sales expansion and operational optimization, we hope to achieve profitability for the Company by 2025. Currently, Hua Medicine is also conducting basic and clinical research on dorzagliatin globally, aiming to continuously expand its indications and target populations, explore new disease areas, and promote human health and well-being.”Progress of Clinical Research and Company Operations- During the first reporting period under the NRDL, dorzagliatin experienced a fast entry into hospital and pharmacies, especially in Shanghai, Beijing, Tianjin where the government policies support market entry for novel new drugs. The number of hospitals prescribing dorzagliatin exceeded 2,100 in the first half of 2024.- Revenue of dorzagliatin reached RMB102.7 million in the first half of 2024 and is expected to continue to grow in the second half of 2024. As we build off our new foundation under the NRDL, we plan to leverage our well-established partnerships to enhance the dorzagliatin manufacturing process, which is expected to lead to efficiencies, expanded capacity and reduction of cost of goods.- We continued our post marketing clinical studies at approximately 80 hospitals to better understand the benefits dorzagliatin provides to patients with Type 2 diabetes and T2D complications, such as memory loss and diabetes kidney disease. Through our collaboration with our clinical research partners in Hong Kong, we have discovered that glucokinase (GK) activation may bring the benefits of reduction of risks in cardiovascular disease, and dyslipidemia. These results (applying the Mendelian Randomization (MR) methodology) certainly expand our understanding of the benefits of GK activation through dorzagliatin and for uncovering new indications of dorzagliatin in the future. Mendelian Randomization (MR) is a statistical method that uses genetic variants to investigate the causal effects of exposures (e.g., treatments) on outcomes (e.g., diseases). Its unique advantage lies in its reduced susceptibility to confounding and time-related biases compared with observational studies, which is achieved by leveraging the random allocation of genetic variants at conception. In evidence-based medicine, the credibility of evidence from MR is considered to be among the highest, second only to that of randomized controlled trials.- We have advanced our post-marketing real world evidence (RWE) studies HMM0601 and HMM0701 in T2D patients in China, and HMM0123 in Hong Kong, China. In these studies, we are collecting evidence in medical practices for optimization of glucose homeostasis either through dorzagliatin alone or in combination with standard care T2D medications such as metformin, DPP-IV inhibitors, SGLT-2 inhibitors, GLP-1RA and insulin. These results create new evidence for dorzagliatin in the expansion of its indication in diabetes prevention and remission.- We are continuing our drug development pipeline with focus on the fixed dose combination (FDC) of new drug candidates. The new drug Dorzagliatin-Metformin FDC entered manufacturing process validation and our plan is to launch this new medicine for Type 2 diabetes in 2028. Additional new FDC drugs with dorzagliatin will be developed for T2D patients, tailored specifically to address T2D patients with associated complications such as obesity and diabetes kidney disease.- To further leverage the unique advantage of dorzagliatin in restoring GLP-1 secretion in patients with diabetes and obesity, Hua Medicine initiated its Phase I study in the United States with our 2nd generation GKA. The trial has been proceeding smoothly and has already completed dose escalation in three cohorts of T2D patients in the United States. The topline data is expected to be available in the fourth quarter of 2024, supporting future drug development.- At the American Diabetes Association (ADA) Annual Meeting 2024, Hua Medicine reported new scientific data supporting the combination of dorzagliatin with a SGLT-2 inhibitor which led to improvement in glycaemic control. Combination of dorzagliatin with chronic kidney disease (CKD) medicine, such as SGLT-2 inhibitor, empagliflozin, in mid to late stage diabetes kidney disease patients, offers new opportunity to expand dorzagliatin’s indication.- We are exploring more drug repurposing opportunities for dorzagliatin using MR framework, such as renal diseases, neuropathy related diseases, eye related diseases, cognitive disorders, and cancers. Animal studies shall be further performed to validate the promising findings.- We are continuing to optimize our protein allosteric modulation technology (PAMT) and expansion from positive allosteric modulator (PAM), such as GK positive allosteric modulator dorzagliatin, to negative allosteric modulator (NAM) in kinase and G-protein-coupled receptors (GPCR) proteins. The GK NAM program advanced to the pre-clinical candidate (PCC) selection stage and final optimization of the PCC to clinical candidate for congenital hyperinsulinism (CHI), and potentially for dyslipidaemia. We continue to advance mGLUR5 NAM program for its clinical potential in Parkinson’s disease (PDLID), Fragile X syndrome (FXS), and drug addiction.Financial highlightsAs of June 30, 2024,- Bank balances and cash position was approximately RMB1,338.8 million.- Total revenue generated by the Company was approximately RMB102.7 million, reflecting sales of approximately 846,000 packs of HuaTangNing .- Total other income was approximately RMB55.1 million, of which approximately RMB47.8 million was attributable to the amortization of Bayer milestone income.- Total expenditures was approximately RMB245.9 million, of which approximately RMB119.8 million was attributable to research and development expenses.Forward-looking StatementThis article contains the statements regarding the future expectations, plans and prospects for Hua Medicine and the investigational product. The forward-looking statements made in this article relate only to the events or information as of the date on which the statements are made in this article. Except as required by law, we undertake no obligation to update or revise publicly any forward-looking statements, whether as a result of new information, future events or otherwise, after the date on which the statements are made or to reflect the occurrence of unanticipated events. You should read this article completely and with the understanding that our actual future results or performance may be materially different from what we expect as a result of various risks, uncertainties, or other legal requirements.About Hua MedicineHua Medicine is an innovative drug development and commercialization company based in Shanghai, China, with companies in the United States and Hong Kong. Hua Medicine focuses on developing novel therapies for patients with unmet medical needs worldwide. Based on global resources, Hua Medicine teams up with global high-calibre people to develop breakthrough technologies and products, which contribute to innovation in diabetes care. Hua Medicine's cornerstone product HuaTangNing (dorzagliatin tablets), targets the glucose sensor glucokinase, restores glucose sensitivity in T2D patients, and stabilizes imbalances in blood glucose levels in patients. HuaTangNing was approved by the National Medical Products Administration (NMPA) of China on September 30th, 2022. It can be used alone or in combination with metformin on hydrochloride-tolerated T2D patients. For patients with chronic kidney disease (CKD), no dose adjustment is required. It is an oral hypoglycemic drug that can be used for patients with Type 2 diabetes with varying degrees of renal function impairment (including end-stage renal impairment without dialysis). Hua Medicine partnered with Bayer, a leading global pharmaceutical company, to commercialize HuaTangNing in China, benefiting diabetic patients and their families.For more informationHua MedicineWebsite: www.huamedicine.comInvestorsE-mail: ir@huamedicine.comMediaE-mail: pr@huamedicine.comDisclaimerFor the accuracy and completeness of the context, references to information related to products launched in China, especially label or requirements, should follow the relevant documents approved by the Chinese regulatory authorities.The above information should not be interpreted as a recommendation or promotion of any drug or treatment regimen, nor should it substitute for the medical advice of any healthcare professional. Please consult a healthcare professional for any matters related to medical treatment. Copyright 2024 ACN Newswire via SeaPRwire.com.

香港, 2024年8月29日 - (亞太商訊 via SeaPRwire.com) — 碧瑤綠色集團有限公司（「碧瑤」或「集團」；股份代號：01397.HK）欣然宣佈截至2024年6月30日止六個月（「期內」）之未經審核之中期業績。期內，集團收益約12.9億港元，較去年增加約16.6%，主要由於集團清潔、廢物處理及回收業務持續增長所致。期內溢利約為25.8百萬港元，較去年同期增加約18.5%。整體毛利增加約12.4%至約97.1百萬港元。業務回顧及展望2024年上半年，集團成功獲得共14.8億港元新合約，成功將集團的手頭合約由2023年12月31日約44.3億港元增加約3.8%至約46.0億港元（截至2024年6月30日），為2024年下半年及日後年度，迎來可觀的收益增長。清潔作為集團的核心業務，繼續於期內錄得增長，收益較去年同期增加20.1%至約10.3億港元，佔集團總收益約80.2%。清潔業務毛利增加7.6%，至約66.4百萬港元，主要由於集團與香港特區政府（「政府」）各部門及不同機構的新清潔服務合約所致。集團為政府轄下的街道清潔服務版圖，覆蓋全香港共七區，服務人口約280萬，標誌碧瑤於香港清潔服務市場的領導地位。集團為食物環境衞生署管理政府場地清潔服務版圖，覆蓋全港七區。另外，集團亦為政府多區轄下的街市及康樂場地提供清潔服務，覆蓋全港各大區，其他清潔場地亦遍及各大醫院、政府診所、香港國際機場、學校、屋苑及私人機構等眾多不同場景，顯示集團的專業服務廣受認可。廢物管理及回收方面，期內收益錄得增長，同比增加約7.4%至約1.47億港元，佔集團總收益約11.4%。廢物管理回收業務的毛利增加約60.7%，至約19.2百萬港元，主要由於「塑膠回收先導計劃」進入收成期，以及相關政府合約增加回收點及收入所致。集團期內為政府轄下的五區提供廢物收集服務，服務人口約160萬，亦為香港數千個回收點（包括塑膠、玻璃樽、金屬、廢紙及廚餘），連同公共場所及學校的回收箱，提供收集服務。期內，集團繼續為環境保護署（「環保署」）的「塑膠回收先導計劃」服務合約，為香港多區提供塑膠收集服務。此外，集團亦為香港眾多環保署轄下的「綠在區區」回收環保站、智能回收機及不同機構提供回收服務，負責香港多區的玻璃容器收集及處理，以及廚餘收集服務。綠色科技業務方面，集團結合多項先進的智能數碼科技和物聯網技術，推出了智能回收系統。透過一站式管理及大數據分析平台，即時了解回收機的情況，並可根據回收量，靈活調配運輸，減少物流成本和不必要的碳排放。集團現時為環保署提供智能回收機，以及為私人屋苑提供智能廚餘回收機。目前智能回收機及智能廚餘回收機已遍及香港不同角落，每日24小時為市民提供便捷的回收體驗，並有助提升香港整體回收量。政府現正積極透過回收基金和環境及自然保育基金，向私人屋苑提供全面的財務支援，作安裝廚餘回收機之用。在政府大力宣傳所創造的市場需求下，預計為集團廚餘回收機以及相關智能科技業務，帶來龐大商機。隨著市場對智能回收的需求日漸上升，集團計劃把握智慧城市發展的契機，致力擴大智能回收機及智能廚餘回收機的市場份額。此外，政府積極推展「塑膠飲料容器及紙包飲品盒生產者責任計劃」，計劃今年將條例法案提交立法會審議，預計2025年推出。貫徹「污染者自付」的原則和「環保責任」的理念，相信有助大幅增加塑膠飲料容器及紙包飲品盒的回收率。受益於該計劃，預計將直接拉動碧瑤回收量，為集團多年來於回收服務建設的投資及競爭壁壘，提供吸引回報。期內，集團與怡和機器有限公司合作位於香港屯門環保園的生物炭工廠已試營運，通過熱解技術將園林廢料轉化為高質量生物炭以作各種應用，從而達到「轉廢為材」的目的。香港在綠色和可持續金融的領域緊貼國際趨勢，加速朝着國際綠色金融中心的方向邁進。為配合可持續發展的需求，集團將可持續發展概念注入核心業務和營運範疇，致力為客戶提供一站式及多元化綠色環境服務及可持續採購方案。未來，碧瑤將投放更多資源在人力培訓及綠色採購。同時，集團透過提供廢物審計服務，提供廢物成份數據，協助企業客戶了解產出廢物的可回收量，實現可持續發展的目標。園藝方面，集團為啟德體育園、中西區海濱長廊及屯門震寰路寵物共享公園提供園藝工程。集團園藝服務的客戶廣泛，涵蓋大型私人住宅、政府處所、學校、商場、酒店、機場、香港科學園、香港科技大學及嶺南大學等。蟲害管理方面，集團期內繼續為黃大仙區及大埔區提供蟲害管理服務。此外，集團分別為古物古蹟辦事處轄下29個古蹟及華人廟宇委員會轄下24間廟宇，提供白蟻防治及監測服務。政府正全速發展北部都會區，預計眾多公營房屋陸續落成，其中古洞北以及粉嶺北新發展區的公共屋邨，預計於2026年開始陸續入伙。北部都會區全面發展後，可提供約50萬個新增房屋單位，相信為集團多個核心業務帶來契機。碧瑤主席吳永康先生指：「政府高度重視環境議題，碧瑤主要業務與民生息息相關，屬社會剛性需求，不受經濟環境影響。即使在經濟疲弱下，集團核心業務依然持續增長。儘管期內垃圾徵費暫緩推行，但政府明顯加大力度通過回收商，增加各類回收點，例如加設夜間廚餘回收流動點，方便市民進行回收，不論質和量均有提升，直接拉動集團的回收業務，帶來增長動力。所以，暫緩推行垃圾徵費不單對集團回收業務沒有構成負面影響，反而業務有所增長。長遠而言，減廢回收有助實現政府中「零廢堆填」的目標，有利集團回收及綠色科技業務的發展。」展望未來，集團在致力提高各核心業務的市場份額的同時，積極於香港及以外地區擴張。同時因應集團的發展，適時尋找潛在的併購、合營、或新業務項目，加速未來業務增長，為股東締造可觀及長遠回報。有關集團2024年度中期業績公告詳情，請瀏覽以下網址：http://www.baguio.com.hk/zh-HK/Investor%20Relations/Announcements%20and%20Notices ~ 完 ~碧瑤綠色集團簡介：碧瑤綠色集團（股份代號：01397.HK）成立於 1980 年，為香港最大的綜合環境服務集團之一，提供環衞保潔、資源回收、循環再造、廢物管理、綠色科技、有機肥料及動物飼料生產、園藝綠化工程及害蟲防治等。集團為不同領域的客戶提供服務，包括政府部門、各大機構及跨國企業。集團努力不懈地提升環境、社會及管治(ESG)的表現，以推進集團的可持續發展，以實現將香港推動成為更清潔、更綠色、更健康城市的願景。 Copyright 2024 亞太商訊 via SeaPRwire.com.

香港, 2024年8月29日 - (亞太商訊 via SeaPRwire.com) — 康希諾生物今日披露了2024年上半年業績報告，營收達到3.03億元，其中流腦結合疫苗家族再度展現强勁增長動力，尤其是ACYW135群腦膜炎球菌多糖結合疫苗（CRM197載體）（以下簡稱“MCV4”）曼海欣®作爲亞洲首個腦膜炎球菌四價結合疫苗産品，不僅填補了市場空白，更爲我國嬰幼兒流腦疾病預防樹立了新標杆。康希諾生物兩款流腦疫苗于2024年上半年實現營業收入約2.623億元，較去年同期顯著增長約18%，同時虧損大幅收窄。MCV4不僅在嬰幼兒市場備受矚目，其擴齡臨床試驗也正穩步推進，旨在覆蓋4周歲及以上兒童及成人群體，進一步擴展使用範圍，滿足更廣泛人群的接種需求。同時，康希諾生物緊跟全球研發步伐，與多家國際頂尖研究機構深化合作，不斷推動産品創新和技術突破，幷加速産業化技術轉移和商業化布局。依托新冠疫苗海外商業化的成功經驗，MCV4疫苗的國際市場拓展已蓄勢待發，以東南亞、中東、北非、南美爲主要目標區域，推動注册和商業化工作。此外，國際市場拓展經驗以及與相關方建立的戰略合作關係，也將助力康希諾生物的13價肺炎結合疫苗、組分百白破疫苗組合等産品在海外市場的准入與商業化。同時，公司也在以WHO PQ認證爲方向進行前期準備和籌劃工作，探索國際組織采購産品的可行性；對于全球創新類産品，也會積極探討于發達國家准入的可行性。在營銷策略上，康希諾生物采用了高效精准的商業化模式，依托自主銷售團隊爲核心，結合專業推廣商的力量，迅速將營銷網絡下沉至縣級地區，實現營銷網絡的全面覆蓋。公司堅持以專業學術和客戶需求爲導向，通過深入調研和終端服務，確保産品精准觸達目標群體，同時有效控制銷售費用，實現集約化運營。截至目前，康希諾生物建立了體系完備的商業運營中心以開展國內外的營銷工作，流腦結合疫苗完成了30個省份的准入工作，全面打開了國內市場。流腦結合疫苗的成功商業化也爲即將獲批的13價肺炎結合疫苗打下堅實基礎，目前該産品正在按計劃進行臨床和生産現場檢查。康希諾生物在降本增效方面也取得了顯著成效，銷售費用和管理費用較同期均有下降，分別降低了約13%和39%，顯示出公司運營效率的不斷提升。總體來看，康希諾生物正穩步向集研發、生産、商業化于一體的全能型Biopharma公司邁進。隨著MCV4商業化的成功和13價肺炎結合疫苗等新産品的逐步獲批上市，公司業績有望持續增長。公司管理層對公司前景充滿信心，幷已通過增持公司股份的實際行動表達了堅定支持。 Copyright 2024 亞太商訊 via SeaPRwire.com.

HONG KONG, Aug 29, 2024 - (ACN Newswire via SeaPRwire.com) - Baguio Green Group Limited (‘‘Baguio’’ or the ‘‘Group’’, Stock Code: 01397.HK) is pleased to announce its unaudited interim results for the six months ended 30 June 2024 (the Period”).During the Period, the Group’s revenue amounted to approximately HK$1,291.1 million, representing an increase of approximately 16.6% as compared to the same period last year, mainly due to the continued increase in revenue in the cleaning segment together with the waste management and recycling segment. Profit for the Period amounted to approximately HK$25.8 million, representing an increase of approximately 18.5% as compared to the same period last year. The overall gross profit increased by approximately 12.4% to approximately HK$97.1 million.Business Overview and ProspectsIn the first half of 2024, new contracts awarded to the Group amounted to a total of HK$1.48 billion. As a result, the Group’s contracts on hand reached approximately HK$4.60 billion (as of 30 June 2024), representing an increase of approximately 3.8% from approximately HK$4.43 billion as of 31 December 2023, providing strong revenue growth in the second half of 2024 and subsequent years.The Group’s core business, cleaning services, recorded growth during the Period. Revenue from cleaning services increased by 20.1% to approximately HK$1,034.9 million, accounting for approximately 80.2% of the Group’s total revenue. Gross profit of the cleaning business increased by 7.6% to approximately HK$66.4 million, mainly due to the Group’s new cleaning service contracts with various HKSAR Government (the “Government”) departments and different institutions.The Group’s Government-related street cleaning services cover a total of seven districts, serving a population of approximately 2.8 million, marking Baguio’s leading position in the Hong Kong cleaning services market. The Group’s Government venue cleaning services for the Food and Environmental Hygiene Department cover seven districts in Hong Kong. In addition, the Group also provided Government market related cleaning services and leisure venues cleaning services, covering several districts in Hong Kong, as well as other cleaning sites such as hospitals, Government clinics, Hong Kong International Airport, schools, housing estates and private institutions, demonstrating that the Group’s professional services are widely recognised.Waste management and recycling business recorded growth in revenue during the Period which increased by approximately 7.4% to approximately HK$147.3 million, accounting for approximately 11.4% of the Group’s total revenue. Gross profit of the waste management and recycling business increased by approximately 60.7% to approximately HK$19.2 million, mainly due to the “Plastic Recycling Pilot Scheme” entered the harvest period and the related contracts with the Government increased the recycling spots and revenue. During the Period, the Group provided Government-related waste collection services to five districts, serving a population of approximately 1.6 million, and provided collection services for thousands of recycling spots (including plastic, glass bottles, metals, waste paper and food waste) across Hong Kong, and collection services for recycling bins in public places and schools. During the Period, the Group provided Baguio continued to provide plastic collection services for several districts under the Environment Protection Department (“EPD”) Plastic Recycling Pilot Scheme contract. Baguio also provides collection services for Recycling Stations of “GREEN@COMMUNITY”, introduced by the EPD and smart recycling machines, and other institutions in Hong Kong. In addition, the Group also provides the Government with glass bottles collection and management services and food waste collection services in several districts in Hong Kong.Regarding green technology business, the Group launched a smart recycling system through combination of a number of advanced smart digital technologies and Internet of Things technologies. Through a one-stop management and big data analytics platform, the Group can monitor the real-time situation of the recycling machines, and flexibly deploy transportation according to the amount of recyclables, reducing logistics costs and unnecessary carbon emissions. The Group currently provides smart recycling machines to the EPD and smart food waste recycling machines to private housing estates. At present, smart recycling machines and smart food waste recycling machines are now available in different places of Hong Kong, providing the public with a convenient recycling experience 24 hours a day, and helping to increase the overall recycling volume in Hong Kong. The Government is proactively offering financial aids for private housing estates to install food waste recycling machines through the Recycling Fund and the Environment and Conservation Fund. Under the expected market demand created by the strong advocacy of the Government, it is believed that the Group’s food waste recycling machines and related smart technology business will bring huge business opportunities. With the increasing market demand for smart recycling, the Group plans to seize the opportunity of smart city development, striving to expand the market share of smart recycling machines and smart food waste recycling machines.In addition, the Government is actively promoting the “Producer Responsibility Scheme on Plastic Beverage Containers and Beverage Cartons”, and plans to table the bill to the Legislative Council for scrutiny this year with a view to introducing it in 2025. Enshrining the principle of “Polluter Pays” and the vision of “Eco-responsibility”, the recycling rate of plastic beverage containers and beverage cartons is expected to have a significant increase. The scheme is expected to directly drive the growth of Baguio’s recycling business and create solid returns from our investment in recycling facilities which creates a strong entry barrier to the competition.In partnership with Jardine Engineering Corporation Limited, the Pilot Biochar Production Plant at the EcoPark in Tuen Mun was commenced trial operation during the Period. By converting yard waste into high-quality biochar with pyrolysis technology for various applications, the production plant effectively “turns waste into useful resources”.Hong Kong has made concerted effort to keep pace with international trends in the field of green and sustainable finance, accelerating its progress towards becoming an international green finance hub. To meet the needs of sustainable development, the Group has incorporated sustainability insights into its core businesses and operations and is committed to providing customers with one-stop and diversified green environmental services and sustainable procurement solutions. In the future, Baguio will invest more resources in personnel training and green procurement. Meanwhile, through the provision of waste audit services, the Group provides waste constituent data to help corporate customers understand the amount of generated waste that can be recycled and achieve sustainable development goals.As for the landscaping business, the Group provided landscaping services for the Kai Tak Sports Park, the Central and Western District Promenade and the Inclusive Park for Pets at Tsun Wen Road in Tuen Mun. In addition, the Group provides landscaping services for a wide range of clients, including large private residences, Government premises, schools, shopping malls, hotels, airports, Hong Kong Science Park, Hong Kong University of Science and Technology and Lingnan University, etc.For pest management business, the Group continued to provide pest management services in Wong Tai Sin and Tai Po districts during the Period. In addition, the Group provided termite control and monitoring services to 29 monuments under the Antiquities and Monuments Office and 24 temples under the Chinese Temples Committee respectively.The Government is developing the Northern Metropolis at full speed and a number of public housing estates are scheduled for completion in phases. In particular, intake of tenants at the public housing estates in northern Kwu Tung North and Fanling North New Development Area will commence progressively from 2026. The Northern Metropolis will provide about 500,000 new housing units after fully developed, which is believed to bring opportunities to the Group’s core businesses.Mr. Ng Wing Hong, Chairman of Baguio, commented, “The Government demonstrates a strong commitment to environmental agenda. Baguio’s core businesses are closely related to the livelihood of the general public and are not affected by the economic environment. Despite the presence of economic headwinds, the Group’s core business continues to demonstrate a growth trajectory.While the implementation of the Waste Charging was postponed during the Period, the Government has significantly increased its efforts to increase various types of recycling spots through recyclers. For example, the addition of night mobile food waste recycling spots to facilitate citizens’ recycling, with improvement in terms of quality and quantity, which directly brings growth impetus to the Group’s recycling business. Therefore, the postponement of Waste Charging has no adverse impact on the Group’s recycling business, and on the contrary, results in an increase in business. In the long run, waste reduction and recycling will help achieve the Government’s goal of “Zero Landfill”, and benefit the development of the Group’s recycling and green technology businesses.”Looking forward, the Group will continue to increase the market share of its core businesses and proactively engage in expansion in Hong Kong and beyond. Meanwhile, in line with the development of the Group, it will actively explore potential mergers and acquisitions, joint ventures or new business projects to accelerate future business growth and deliver substantial and long-term returns to shareholders.For details of the Group's 2024 interim results announcement, please visit the following website:http://www.baguio.com.hk/en-US/Investor%20Relations/Announcements%20and%20Notices- End -About Baguio Green GroupEstablished in 1980, Baguio Green Group (Stock code: 01397.HK) is one of Hong Kong’s largest integrated environmental services groups. It provides a full spectrum of professional services including professional cleaning, waste collection & recycling, waste management, green technology, organic fertilizer and animal feed production, horticulture & landscaping, and pest control. It serves a wide range of customers in various sectors including Government departments, statutory organizations and multinational corporations. Fully committed to ESG, the Group works relentlessly to advance sustainable development and create a cleaner, greener, healthier city. Copyright 2024 ACN Newswire via SeaPRwire.com.

HONG KONG, Aug 29, 2024 - (ACN Newswire via SeaPRwire.com) - CanSino Biologics Inc. (CanSinoBIO) today disclosed its performance report for the first half of 2024, with revenue reaching 303 million yuan, while losses were substantially reduced. The meningococcal conjugate vaccines demonstrated robust growth, particularly the Group ACYW135 Meningococcal Conjugate Vaccine (CRM197), known as MCV4 or Menhycia®. As the first quadrivalent meningococcal conjugate vaccine product in Asia, it not only fills the market gap, but also provides a better choice for the prevention of meningococcal disease in Chinese infants and young children. In the first half of 2024, CanSinoBIO's two meningococcal vaccines generated approximately 263 million yuan in revenue, marking a significant increase of around 18% compared to last year.In addition, CanSinoBIO is making strides in clinical trials for expanding the age group of MCV4, aiming to cover children aged four and above, as well as adults. This initiative seeks to broaden vaccination coverage to meet the needs of a wider population. Concurrently, the company is advancing the international market expansion of the MCV4, leveraging its successful overseas commercialization experience with its COVID-19 vaccine. CanSinoBIO is deepening collaborations with leading international research institutions, focusing on registration and commercialization in Southeast Asia, the Middle East, North Africa, and South America. It indicates that the company is accelerating the commercial layout in the global market.Moreover, the market expansion experiences and strategic partnerships will support to expand the reach of its PCV13i [13-valent pneumococcal conjugate vaccine (CRM197, TT Vector)] and DTcP (diphtheria, tetanus and acellular pertussis) components vaccine franchise in global markets. The company is also planning and preparing for WHO PQ certification, exploring the feasibility of international organizations. For global innovative products, CanSinoBIO will actively explore the possibility of accessing developed countries.In terms of commercialization strategy, CanSinoBIO has adopted an efficient and precise model, relying on its direct sales team and leveraging professional promoters to rapidly extend its marketing network to the county-level areas. The company adheres to a professional academic and customer-oriented approach, ensuring that products reach target groups through in-depth research and terminal services. This approach helps control sales expenses and achieves intensive operations. To date, CanSinoBIO has established a well-structured commercial operation center for both domestic and international markets. The MCV4 has been approved in 30 provinces in China, comprehensively opening up the domestic market. The successful commercialization of MCV4 has laid a solid foundation for the upcoming PCV13i, which is currently undergoing clinical and manufacturing site inspections as planned.CanSinoBIO has also made significant progress in cost reduction and efficiency improvement, with sales and administrative expenses decreasing by approximately 13% and 39% compared to the same period last year, respectively, reflecting ongoing improvements in operational efficiency.Overall, CanSinoBIO has integrated R&D, production, and commercialization, gradually transforming into a biopharmaceutical company. With the successful commercialization of MCV4 and the upcoming approval and launch of new products like PCV13i, CanSinoBIO's performance is expected to continue growing. The company’s management team is confident on the company's prospects and has demonstrated strong support through increasing shareholdings. Copyright 2024 ACN Newswire via SeaPRwire.com.